at Host initiated state control of remote client in communications system By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A system and method for low-cost, fault tolerant, EMI robust data communications, particularly for an EV environment. A data communications method, including a) enabling a transmission of a wake signal from a host to a remote client through an isolator disposed at the remote client when the wake signal is asserted from the host at a host-portion of the isolator concurrent with a periodic enablement of a client-portion of the isolator by the remote client; and thereafter b) transmitting the wake signal from the host to the remote client through the isolator; c) controlling enablement of the client-portion responsive to the wake signal transmitted through the isolator; and thereafter d) disabling the transmission by deassertion of the wake signal at the host. Full Article
at Method and apparatus for power-efficiency management in a virtualized cluster system By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A method and apparatus for power-efficiency management in a virtualized cluster system. The virtualized cluster system includes a front-end physical host and at least one back-end physical host, and each of the at least one back-end physical host comprises at least one virtual machine and a virtual machine manager. Flow characteristics of the virtualized cluster system are detected at a regular time cycle, then a power-efficiency management policy is generated for each of the at least one back-end physical host based on the detected flow characteristics, and finally the power-efficiency management policies are performed. The method can detect the real-time flow characteristics of the virtualized cluster system and make the power-efficiency management policies thereupon to control the power consumption of the system and perform admission control on the whole flow, thereby realizing optimal power saving while meeting the quality of service requirements. Full Article
at Power shifting in multicore platforms by varying SMT levels By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT Power consumption in a microprocessor platform is managed by setting a peak power level for power consumed by a multi-core microprocessor platform executing multi-threaded applications. The multi-core microprocessor platform contains a plurality of physical cores, and each physical core is configurable into a plurality of logical cores. A simultaneous multithreading level in at least one physical core is adjusted by changing the number of logical cores on that physical core in response to a power consumption level of the multi-core microprocessor platform exceeding the peak power level. Performance and power data based on simultaneous multi-threading levels are used in selecting the physical core to be adjusted. Full Article
at Methods and apparatuses for controlling the temperature of a data processing system By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT Methods and apparatuses to manage working states of a data processing system. At least one embodiment of the present invention includes a data processing system with one or more sensors (e.g., physical sensors such as tachometer and thermistors, and logical sensors such as CPU load) for fine grain control of one or more components (e.g., processor, fan, hard drive, optical drive) of the system for working conditions that balance various goals (e.g., user preferences, performance, power consumption, thermal constraints, acoustic noise). In one example, the clock frequency and core voltage for a processor are actively managed to balance performance and power consumption (heat generation) without a significant latency. In one example, the speed of a cooling fan is actively managed to balance cooling effort and noise (and/or power consumption). Full Article
at Multi-cluster processing system and method of operating the same By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A multi-cluster processing system and a method of operating a multi-cluster processing system are provided. The multi-cluster processing system includes: a first cluster including a plurality of first-type cores: a second cluster including a plurality of second-type cores; and a control unit configured to monitor loads of the first-type cores and the second-type cores, wherein when utilization of at least one of enabled first-type cores exceeds a predetermined threshold utilization of each of the first-type cores, the control unit enables at least one of disabled first-type cores in a first mode, and the control unit enables at least one of the disabled second-type cores and disables the first cluster in a second mode, wherein an amount of computation per unit of time of each of the second-type cores is greater than an amount of computation per unit of time of each of the first-type cores. Full Article
at Image forming apparatus, system-on-chip (SoC) unit, and driving method thereof By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT An image forming apparatus is connected to a host device including first and second power domains which are separately supplied with power and includes first and second memories to be disposed in the second power domain, a main controller disposed in the first power domain and to perform a control operation using the first memory in a normal mode, and a sub-controller disposed in the second power domain and perform a control operation using the second memory in a power-saving mode, where when the normal mode is changed to the power-saving mode a power supply to the first power domain is shut off, the first memory operates in a self-refresh mode, and the main controller copies central processing unit (CPU) context information into a context storage unit, and when the power-saving mode is changed to the normal mode, the main controller is booted using the CPU context information stored in the context storage unit. Full Article
at Methods, systems, apparatuses, and computer-readable media for waking a SLIMbus without toggle signal By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT Arrangements for restarting data transmission on a serial low-power inter-chip media bus (SLIMbus) are presented. A clock signal may be provided in an active mode to a component communicatively coupled with the SLIMbus. Immediately prior to the clock signal in the active mode being provided, the clock signal may have been in a paused mode. While the clock signal was in the paused mode at least until the clock signal is provided in the active mode, the data line may have been inactive (e.g., a toggle on the data line may not have been present). Frame synchronization data for a frame may be transmitted. The frame synchronization data for the frame, as received by the component, may not match expected frame synchronization data. Payload data may be transmitted as part of the frame to the component, wherein the payload data is expected to be read properly by the component. Full Article
at Identification and management of unsafe optimizations By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT Techniques for implementing identification and management of unsafe optimizations are disclosed. A method of the disclosure includes receiving, by a managed runtime environment (MRE) executed by a processing device, a notice of misprediction of optimized code, the misprediction occurring during a runtime of the optimized code, determining, by the MRE, whether a local misprediction counter (LMC) associated with a code region of the optimized code causing the misprediction exceeds a local misprediction threshold (LMT) value, and when the LMC exceeds the LMT value, compiling, by the MRE, native code of the optimized code to generate a new version of the optimized code, wherein the code region in the new version of the optimized code is not optimized. Full Article
at Method for operating invisible system services on android platform By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A method for operating an invisible system service on Android platform is disclosed. The method for operating system services on Android platform includes selectively registering a created system service in a context manager according to a type of the created system service, where the type of the system service comprises a first type for permitting access from an outside and a second type for not permitting access from the outside, and the selectively registering comprises registering in the context manager the created system service belonging to the first type and not registering in the context manager the created system service belonging to the second type. Full Article
at Method and apparatus for rejecting untrusted network By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A method of accessing a communication system and a communication device for performing the same are disclosed. The method includes transmitting, by a communication device to a node of a communication system through a communication link between the communication device and the node, a request to negotiate basic capabilities for communicating with the node, receiving, by the communication device from the node, a response to the request to negotiate basic capabilities, and, transmitting, by the communication device to the node, a request to disconnect the communication link, when the response to the request to negotiate basic capabilities indicates that the node does not support authentication. Full Article
at Contactless authentication of optical disk drives By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT An optical disc drive (ODD) includes a radio-frequency identification (RFID) reader. The reader includes a circuit and a coil antenna which has a rotational symmetry with respect to a rotation axis of a motor, shaft and turntable of the ODD. The coil antenna can be secured to a wall of a housing of the ODD or around the motor and/or shaft. The reader can read an RFID tag on an optical disc. The RFID tag includes a circuit and a coil antenna which has a rotational symmetry with respect to the disc. As a result, the RFID tag can be read while the disc is rotating. A magnetic insulating material such as a ferrite polymer composite film is used to magnetically insulate the coil antenna. An authentication code can be read from the RFID tag to control access to content of the optical disc. Full Article
at Variable domain resource data security for data processing systems By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT The variable domain data access control system and method described herein use the same variable domain to describe a data security model and a variable domain data model, such as a product configuration model. A variable domain is a set of resource data that can be described using a logical relationship data structure. The variable domain utilizes logical relationship expressions, such as a Boolean logic language, to define resource data in terms of parts, rules and/or attributes, and any other property that can be accessed for viewing, manipulation, or other purposes. The data security model represents an access control list (ACL) that includes security attributes as resource data and uses the same data structure and logical relationship expressions as an associated variable domain data model. An application, such as a configuration engine, can be used to create controlled access to the variable domain data model using the data security model. Full Article
at Apparatus for controlling processor execution in a secure environment By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT Various embodiments described herein relate to apparatus for executing software in a secure computing environment. A secure processor can be used and configured to request a context swap from a first context to a second context when switching execution from a first portion of software to a second portion of software. A context manager, which can be in communication with the secure processor, can be configured to receive and initiate a requested context swap. A trust vector verifier, which can be in communication with the secure processor and the context manager, can be configured to load a trust vector descriptor upon command from a context manager. Full Article
at Method of processing data to enable external storage thereof with minimized risk of information leakage By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A method is provided to process data so that the data can be externally stored with minimized risk of information leakage. A framework (virtual execution framework) based on virtual machines (VMs) is utilized as a substitute for a trusted institution. Encryption of consolidated data can reduce risk of information leakage and enhance security. Since the virtual execution framework can control connection and direction of communication, financial institutions are allowed to apply encryption to data on their own, which makes the data further appropriate for external storage. By allowing financial institutions to apply their own decryption, it is possible to prevent one of two financial institutions from retrieving externally stored data into the external execution framework without intervention of the other. Additionally, associated acting subjects can be provided with freedom depending on the degree of information leakage risk. Full Article
at System, method, and device for delivering communications and storing and delivering data By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A system, method, and device includes a platform data storage that stores a wrap that secures an executable controller and executable sensors. The wrap is verified, optionally through a downloaded authentication driver. After verifying the wrap, the wrap is opened and a sister of the executable controller is installed into the platform memory to cooperate with the executable controller. Additionally or alternatively, the authentication driver may cooperate with the executable controller. The executable controller allows the platform processor to access data secured in a vault and/or verify the platform to create a connection to a connection server. Full Article
at Secured wireless access system and related method By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT The disclosure is directed to a system and method for establishing a secured wireless connection allowing the exchange of information between a wireless device and aircraft equipment. The secured wireless access system may require a user controlling the wireless device to interact with an onboard interface to initiate a connection. The user may be further required to enter a randomly generated security passcode to pair the mobile device to the aircraft equipment. Further security measures may be implemented, such as tiered user access levels restricting certain equipment and/or information based upon a user identity of the user requesting access. Full Article
at Apparatus and method for managing power of an electronic appliance By www.freepatentsonline.com Published On :: Tue, 21 Jul 2015 08:00:00 EDT There is provided a power management apparatus including: a managed appliance registering unit carrying out authentication on an electronic appliance connected to a power network and registering an electronic appliance for which the authentication has succeeded as a managed appliance, a control unit controlling operation of the managed appliance and supplying of power to the managed appliance, a managed appliance information acquiring unit acquiring, from the managed appliance, as managed appliance information, at least any of appliance information including identification information that is unique to the electronic appliance, information indicating an operation state of the electronic appliance, information indicating an usage state of the electronic appliance and power information of the electronic appliance, and an appliance state judging unit judging a state of the managed appliance based on the managed appliance information acquired by the managed appliance information acquiring unit. Full Article
at Data transform method and data transformer By www.freepatentsonline.com Published On :: Tue, 18 Aug 2015 08:00:00 EDT A data transform method and a data transformer. The method includes: importing a data transform rule; acquiring from the data transform rule a source data definition, a destination data definition and a data transform rule definition; predicting resource energy consumption parameters of a data transform node server according to the source data definition, the destination data definition and the data transform rule definition; and deploying a resource energy consumption optimization policy of the data transform node server according to the predicted resource energy consumption parameters of the data transform node server. Full Article
at Computer system for storing and retrieval of encrypted data items, client computer, computer program product and computer-implemented method By www.freepatentsonline.com Published On :: Tue, 22 Sep 2015 08:00:00 EDT A system is disclosed comprising multiple sets of client computers each client computer having installed thereon an application program The application program comprising client computer specific log-in information, a database system coupled to the set of client computers via a network. The database system having a log-in component for logging-in the client computers, and being partitioned into multiple relational databases each one of which is assigned to one set of the sets of client computers. Each database further storing encrypted data items, each data item being encrypted with one of the user or user-group specific cryptographic keys, the key identifier of the cryptographic key with which one of the data items is encrypted being stored in the database as an attribute of the one of the encrypted data items. The log-in component comprising assignment information indicative of the assignment of the databases to the set of client computers. Full Article
at Biometric attribute anomaly detection system with adjusting notifications By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A system, methods and server for monitoring health and safety of individuals in a population and sending alert notifications when exceptions are detected include comparing biometric data obtained from the individuals to a biometric model generated for the individual through computer-learning methods. Biometric data may be gathered by wireless biometric sensor devices which transmit biometric data to receiver devices, which relay the biometric data to a server. The biometric model may be maintained in the server and include nominal and threshold biometric parameters for each individual based on biometric sensor data gathered or analyzed over a period of time. An alert may be issued by the server when an individual's biometric data is outside a threshold in the biometric model. The transmitted alert may depend upon the nature of the exception, user settings and past notification experience. Alerts may be escalated when not answered within defined durations. Full Article
at Diagnostic radio frequency identification sensors and applications thereof By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT An integrated passive wireless chip diagnostic sensor system is described that can be interrogated remotely with a wireless device such as a modified cell phone incorporating multi-protocol RFID reader capabilities (such as the emerging Gen-2 standard) or Bluetooth, providing universal easy to use, low cost and immediate quantitative analyses, geolocation and sensor networking capabilities to users of the technology. The present invention can be integrated into various diagnostic platforms and is applicable for use with low power sensors such as thin films, MEMS, electrochemical, thermal, resistive, nano or microfluidic sensor technologies. Applications of the present invention include on-the-spot medical and self-diagnostics on smart skin patches, Point-of-Care (POC) analyses, food diagnostics, pathogen detection, disease-specific wireless biomarker detection, remote structural stresses detection and sensor networks for industrial or Homeland Security using low cost wireless devices such as modified cell phones. Full Article
at Method and system for determining treatments by modifying patient-specific geometrical models By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT Systems and methods are disclosed for evaluating cardiovascular treatment options for a patient. One method includes creating a three-dimensional model representing a portion of the patient's heart based on patient-specific data regarding a geometry of the patient's heart or vasculature; and for a plurality of treatment options for the patient's heart or vasculature, modifying at least one of the three-dimensional model and a reduced order model based on the three-dimensional model. The method also includes determining, for each of the plurality of treatment options, a value of a blood flow characteristic, by solving at least one of the modified three-dimensional model and the modified reduced order model; and identifying one of the plurality of treatment options that solves a function of at least one of: the determined blood flow characteristics of the patient's heart or vasculature, and one or more costs of each of the plurality of treatment options. Full Article
at Automatic detection and correction of magnetic resonance imaging data By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT Systems and methods for processing magnetic resonance imaging (MRI) data are provided. A method includes receiving MRI data comprising a plurality of k-space points and deriving a plurality of image data sets based on the MRI data, each of the plurality of MRI image sets obtained by zeroing a different one of the plurality of k-space points. The method further includes computing image space metric values for each of the plurality of image data sets and adjusting a portion of the MRI data associated with ones of the image space metric values that fail to meet a threshold value to yield adjusted MRI data. Full Article
at System and method for automatic detection of a plurality of SPO2 time series pattern types By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT The disclosed embodiments relate to pulse oximetry. An exemplary pulse oximeter comprises a probe that is adapted to be attached to a body part of a patient to create a signal indicative of an oxygen saturation of blood of the patient, and a processor that is adapted to receive the signal produced by the probe, to calculate an SPO2 value based on the signal, to detect a plurality of pattern types of SPO2 indicative of pathophysiologic events, and to produce an output indicative of a detected one of the plurality of pattern types. Full Article
at MRI-guided localization and/or lead placement systems, related methods, devices and computer program products By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT MRI compatible localization and/or guidance systems for facilitating placement of an interventional therapy and/or device in vivo include: (a) a mount adapted for fixation to a patient; (b) a targeting cannula with a lumen configured to attach to the mount so as to be able to controllably translate in at least three dimensions; and (c) an elongate probe configured to snugly slidably advance and retract in the targeting cannula lumen, the elongate probe comprising at least one of a stimulation or recording electrode. In operation, the targeting cannula can be aligned with a first trajectory and positionally adjusted to provide a desired internal access path to a target location with a corresponding trajectory for the elongate probe. Automated systems for determining an MR scan plane associated with a trajectory and for determining mount adjustments are also described. Full Article
at Magnetic resonance imaging apparatus and magnetic resonance imaging method By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A magnetic resonance imaging apparatus includes an acoustic control unit and an image data acquisition unit. The acoustic control unit applies a gradient magnetic field for controlling a sound in synchronization with a signal representing a respiratory body motion. The image data acquisition unit acquires imaging data by subsequently imaging to control the sound and generate image data based on the imaging data. Full Article
at Biopsy marker with in situ-generated imaging properties By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT An intracorporeal marker, for marking a site within living tissue of a host, includes an outer body portion of biodegradable material. An inner body portion is located in the outer body portion. The inner body portion includes biological material that becomes calcified in the living tissue of the host over time. An agent interacts with the biological material to promote calcification of the biological material of the inner body portion in the living tissue of the host. Full Article
at Lymphatic pressure-measuring system and method for controlling same By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT The present invention has an object to measure lymphatic pressure with more safety and ease at lower cost. To achieve this, a lymphatic pressure-measuring system 1 includes: a manchette 11 fitted on a vital observation portion; a measurement unit 13 that measures and outputs pressure of the manchette 11; an infrared camera 21 that detects fluorescence emitted from fluorescent dye previously injected into a lymph vessel in the vital observation portion; and an image processing device 22 that generates and displays an image showing a position of the fluorescent dye in the lymph vessel based on a detection result of the infrared camera 21. The infrared camera 21 repeats the detection while the pressure of the manchette 11 decreases from first pressure to block a lymph flow in the vital observation portion to second pressure at restart of the lymph flow. The measurement unit 13 repeats the measurement during the period. Full Article
at Heart rate correction system and methods for the detection of cardiac events By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A device for detecting a cardiac event is disclosed. Detection of an event is based on a test applied to a parameter whose value varies according to heart rate. Both the parameter value and heart rate (RR interval) are filtered with an exponential average filter. From these filtered values, the average change in the parameter and the RR interval are also computed with an exponential average filter. Before computing the average change in the parameter, large changes in the parameter over short times, which may be caused by body position shifts, are attenuated are removed, so that the average change represents an average of small/smooth changes in the parameter's value that are characteristic of acute ischemia, one of the cardiac events that may be detected. The test to detect the cardiac event depends on the heart rate, the difference between the parameter's value and its upper and lower normal values, and its average change over time, adjusted for heart rate changes. The upper and lower normal parameter values as a function of heart rate are determined from long term stored data of the filtered RR values and parameter values. Hysteeresis related data and transitory deviations from normal (e.g. vasospasm related data) are excluded from the computation of normal upper and lower parameter bounds. Full Article
at Method and system for facilitating remote medical diagnosis and consultation By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A system for facilitating remote medical diagnosis and consultation of heart disease for a patient, the system comprising: a diagnostic device for performing Electrocardiography on the patient, a network device in communication with the diagnostic device via wired or wireless communication links, a software program pre-installed in the network device, a server located remotely, wherein during operation, the patient activates the diagnostic device which will perform Electrocardiography on the patient, the diagnostic device receives diagnostic data and transmits the diagnostic data to the network device, the software program transmit the diagnostic data to over a network to a server which a physician have access to, and based on the diagnostic data gathered by the server and some additional medical data, the physician can review the patient's health condition and offer an appropriate feedback and diagnosis for the patient. Full Article
at Biometric monitoring device with heart rate measurement activated by a single user-gesture By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A biometric monitoring device measuring various biometric information is provided that allows the person to take and/or display a heart rate reading by a simple user interaction with the device, e.g., by simply touching a heart rate sensor surface area or moving the device in a defined motion pattern. Some embodiments of this disclosure provide biometric monitoring devices that allow a person to get a quick heart rate reading without removing the device or interrupting their other activities. Some embodiments provide heart rate monitoring with other desirable features such as feedback on data acquisition status. Full Article
at Apparatus and method for measuring physiological signal quality By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT An apparatus and method for determining a signal quality of an input signal representing a repetitious phenomena derived from at least one sensor connected to a patient is provided. A detector receives the input signal and determines data representing the repetitious phenomena from the input signal for use in determining at least one patient parameter. A measurement processor is electrically coupled to the detector that determines a first signal quality value by identifying at least one feature of the repetitious phenomena data and compares the at least one feature of a first set of the determined repetitious phenomena data with a second set of the determined repetitious phenomena data to determine a feature variability value and using the feature variability value to determine a stability value representative of the quality of the input signal. Full Article
at Apparatus and method for monitoring and treatment of brain disorders By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A method and system for treating brain disorders comprises detecting activity of a first target area of the brain via a first implanted sensor and determining the presence of target brain activity by analyzing the detected brain activity in combination with treating the user based upon the determined presence of target brain activity by supplying a first therapeutic agent to the first target area via a first implanted fluid delivery member including at least one distal opening adjacent to the first target area. In addition, the system may be used as well for testing the effectiveness of drugs. Full Article
at Method and apparatus for eliminating loading and electrode polarization effects in impedance measurements for tissues and electrolytes By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A device and method for accurately characterizing tissue impedance employs multiple electrodes at a plurality of separation distances to cancel the effects of front end loading leakage currents and electrode polarization to improve the accuracy of sensitive impedance measurements used to identify cancerous tissues. These measurements may be automated over a range of frequencies. Full Article
at 3D ultrasound system for intuitive displaying to check abnormality of object and method for operating 3D ultrasound system By www.freepatentsonline.com Published On :: Tue, 02 Jun 2015 08:00:00 EDT Provided are a three-dimensional (3D) ultrasound system and a method for operating the 3D ultrasound system, which are capable of intuitively displaying the abnormality of an object by determining a grade by comparing measurement data obtained by measuring ultrasound data relating to the object and displaying the measurement data in a different way based on the determined grade. Full Article
at Information processing for a body motion signal By www.freepatentsonline.com Published On :: Tue, 09 Jun 2015 08:00:00 EDT An information processing method includes the following steps: applying a pattern matching process on the body motion signal information, and extracting rhythm cycle candidate waves which are rhythm cycle candidates related to the rhythmic motion; performing −1 or more times integration on the body motion signal information to obtain a motion trajectory, and performing coarse-graining on the motion trajectory to produce an auxiliary wave; superimposing the rhythm cycle candidate waves which are extracted in the process of extracting the cycle candidate waves, on the obtained auxiliary wave, and selecting a cycle of a rhythm cycle candidate wave which has a peak in the auxiliary wave, as a true cycle; and finally obtaining a result of the processing. Full Article
at Magnetic configuration and timing scheme for transcranial magnetic stimulation By www.freepatentsonline.com Published On :: Tue, 30 Jun 2015 08:00:00 EDT Transcranial magnetic stimulation (TMS) is a remarkable tool for probing the brain. However, it is still unclear why specific regions in the cortex are excitable by TMS while others are not. This invention provides methods and tools for the design of efficient magnetic stimulators. Such stimulators can excite neuronal networks that were not sensitive to stimulation until now. Stimulation can be carried out both in-vitro and in-vivo. Novel systems and techniques of this invention will enable both treatment and diagnostics by stimulating regions of the brain or neuronal assemblies that were previously unaffected by TMS. Full Article
at Apparatus for indicating locus of an ultrasonic probe, ultrasonic diagnostic apparatus By www.freepatentsonline.com Published On :: Tue, 21 Jul 2015 08:00:00 EDT An apparatus and method for indicating locus of an ultrasonic probe configured to transmit and receive ultrasonic waves toward a part of a subject wherein a position or movement of the ultrasonic probe is detected, and a locus of the ultrasonic probe on an image of the part of the subject is indicated according to the detected position or movement. Full Article
at Apparatus and methods for determining a plurality of local calibration factors for an image By www.freepatentsonline.com Published On :: Tue, 29 Sep 2015 08:00:00 EDT Apparatus and methods are described including acquiring a first set of extraluminal images of a lumen, using an extraluminal imaging device. At least one of the first set of images is designated as a roadmap image. While an endoluminal device is being moved through the lumen, a second set of extraluminal images is acquired. A plurality of features that are visible within images belonging to the second set of extraluminal images are identified. In response to the identified features in the images belonging to the second set of extraluminal images, a plurality of local calibration factors associated with respective portions of the roadmap image are determined. Other applications are also described. Full Article
at Amino acid derivatives and absorbable polymers therefrom By www.freepatentsonline.com Published On :: Tue, 21 Apr 2015 08:00:00 EDT The present invention relates to the discovery of new class of hydrolysable amino acid derivatives and absorbable polyester amides, polyamides, polyepoxides, polyureas and polyurethanes prepared therefrom. The resultant absorbable polymers are useful for drug delivery, tissue engineering, tissue adhesives, adhesion prevention, bone wax formulations, medical device coatings, stents, stent coatings, highly porous foams, reticulated foams, wound care, cardiovascular applications, orthopedic devices, surface modifying agents and other implantable medical devices. In addition, these absorbable polymers should have a controlled degradation profile. Full Article
at Processes for the preparation of fesoterodine By www.freepatentsonline.com Published On :: Tue, 21 Apr 2015 08:00:00 EDT The invention relates to improved process for the preparation of fesoterodine and its pharmaceutically acceptable salt, specifically fesoterodine fumarate of formula (1). The invention relates to solid state forms of a novel salt of fesoterodine and process for the preparation thereof. The invention also relates to highly pure fesoterodine fumarate substantially free of impurity X at RRT 1.37. The invention also provides solid particles of pure fesoterodine fumarate wherein 90 volume-percent of the particles (D90) have a size of higher than 200 microns. Full Article
at Chemically amplified resist composition and patterning process By www.freepatentsonline.com Published On :: Tue, 28 Apr 2015 08:00:00 EDT A chemically amplified resist composition comprising a base polymer and an amine quencher in the form of a β-alanine, γ-aminobutyric acid, 5-aminovaleric acid, 6-aminocaproic acid, 7-aminoheptanoic acid. 8-aminooctanoic acid or 9-aminononanoic acid derivative having an unsubstituted carboxyl group has a high contrast of alkaline dissolution in rate before and after exposure and forms a pattern of good profile at a high resolution, minimal roughness and wide DOF. Full Article
at Patterning process and resist composition By www.freepatentsonline.com Published On :: Tue, 28 Apr 2015 08:00:00 EDT A negative pattern is formed by coating a resist composition comprising a polymer comprising recurring units having a tertiary ester type acid labile group having a plurality of methyl or ethyl groups on alicycle and an acid generator onto a substrate, prebaking, exposing to high-energy radiation, baking, and developing in an organic solvent developer so that the unexposed region of resist film is dissolved away and the exposed region of resist film is not dissolved. The resist composition exhibits a high dissolution contrast during organic solvent development and forms a fine hole or trench pattern of dimensional uniformity. Full Article
at Phenylcarbamate compound and muscle relaxant containing the same By www.freepatentsonline.com Published On :: Tue, 28 Apr 2015 08:00:00 EDT A novel phenylcarbamate compound and a pharmaceutical composition containing the same are provided. More specifically, a novel phenylcarbamate compound, a composition for muscle relaxation containing the phenylcarbamate compound as an active ingredient, and a method of muscle relaxation comprising administering a therapeutically effective amount of the phenylcarbamate compound, are provided. Full Article
at Feed additive for animals of P-thymol, salt derivative or ester derivative thereof By www.freepatentsonline.com Published On :: Tue, 28 Apr 2015 08:00:00 EDT A feed additive includes at least one of p-thymol, a salt derivative and an ester derivative thereof for animals. Full Article
at 5-aminolevulinic acid derivatives, methods for their preparation and uses thereof By www.freepatentsonline.com Published On :: Tue, 28 Apr 2015 08:00:00 EDT The present invention provides drug conjugates comprising 5-aminolevulinic acid (ALA), an aldehyde and a carboxylic acid that may function as a histone deacetylase inhibitor (HDACI). These conjugates may serve as co-drugs which release a plurality of active species in vivo. The novel drug conjugates may be used, for the treatment or prevention of cancer in PDT-dependent and/or PDT-independent (nonPDT) treatments, as well as for cosmetic uses. In addition the present invention provides novel uses for both the novel and known compounds. According to some embodiments, the present invention provides drug conjugates (co-drugs) comprising (i) ALA, (ii) an aldehyde and (iii) a carboxylic acid that may function as a histone deacetylase inhibitor (HDACO for the treatment of anemia and/or for the induction of erythropoiesis. Full Article
at Process for the preparation of the monomer pentabromobenzyl acrylate and polymerization thereof By www.freepatentsonline.com Published On :: Tue, 28 Apr 2015 08:00:00 EDT The invention relates to a process for preparing pentabromobenzyl acrylate through the reaction of pentahalobenzyl halide with a salt of acrylic acid in water-immiscible solvent, wherein said salt is in aqueous form and the reaction is carried out in the presence of a phase transfer catalyst. A process for polymerizing the pentabromobenzyl acrylate in halogenated aromatic solvent and the poly (pentabromobenzyl acrylate) obtained are also disclosed. Full Article
at Process for functionalization of unsaturated compounds By www.freepatentsonline.com Published On :: Tue, 28 Apr 2015 08:00:00 EDT The present invention relates to a process for synthesizing a multifunctional compound, including the reaction of a compound of formula (II) with atmospheric or molecular oxygen, in the presence of at least one aldehyde of formula (III), and optionally in the presence of at least one catalyst or at least one radical initiator; wherein: R10, R20, R30, R40, R50, L2, R60, R7, R8, and R9 are as described in the claims. The invention also relates to the use of these compounds as monomers for the preparation of polyurethane. The invention also relates to the use of these compounds as monomers of polymers or of biopolymers. Full Article
at Method for the production of 2-octyl acrylate by means of transesterification By www.freepatentsonline.com Published On :: Tue, 28 Apr 2015 08:00:00 EDT The invention relates to the production of 2-octylacrylate of high purity and in good yield using ethyl titanate in solution in 2-octanol or 2-octyl titanate as a transesterification catalyst. Full Article
at Bis-acylated hydroxylamine derivatives By www.freepatentsonline.com Published On :: Tue, 28 Apr 2015 08:00:00 EDT The invention provides certain bis-acylated hydroxylamine derivative compounds, pharmaceutical compositions and kits comprising such compounds, and methods of using such compounds or pharmaceutical compositions. In particular, the invention provides methods of using such compounds or pharmaceutical compositions for treating, preventing, or delaying the onset and/or develop of a disease or condition. In some embodiments, the disease or condition is selected from cardiovascular diseases, ischemia, reperfusion injury, cancerous disease, pulmonary hypertension and conditions responsive to nitroxyl therapy. Full Article