Optimizing differential expression analysis for proteomics data via high-performing rules and ensemble inference  Nature.com

EXCRETE workflow enables deep proteomics of the microbial extracellular environment | Communications Biology  Nature.com

Automated single-cell proteomics providing sufficient proteome depth to study complex biology beyond cell type classifications  Nature.com

Serum proteomics reveal APOE-ε4 -dependent and APOE-ε4 -independent protein signatures in Alzheimer’s disease  Nature.com

quantms: a cloud-based pipeline for quantitative proteomics enables the reanalysis of public proteomics data  Nature.com

Proteomic signatures improve risk prediction for common and rare diseases  Nature.com

A multi-species benchmark for training and validating mass spectrometry proteomics machine learning models  Nature.com

Spatial proteomics identifies JAKi as treatment for a lethal skin disease  Nature.com

Proteomic scores and dietary patterns  Nature.com

An Inflection Point in High-Throughput Proteomics with Orbitrap Astral: Analysis of Biofluids, Cells, and Tissues  ACS Publications

Spatial proteomics of single cells and organelles on tissue slides using filter-aided expansion proteomics  Nature.com

Deep Plasma Proteomics with Data-Independent Acquisition: Clinical Study Protocol Optimization with a COVID-19 Cohort  ACS Publications

Application of Proteomics in Cancer: Recent Trends and Approaches for Biomarkers Discovery  Frontiers

Seer Showcases Deep Proteomics Capabilities, Announces Co-Marketing Deal with Thermo Fisher Scientific  Genetic Engineering & Biotechnology News

Proteomic analysis of the combined effects of cannabigerol and 3- O -ethyl ascorbic acid on kinase-dependent signalling in UVB-irradiated human keratinocytes  Nature.com

As part of its continued efforts to enhance the security of riders and our employees, the Chicago Transit Authority (CTA) today announced the pilot implementation of a proactive Artificial Intelligence (AI)-based technology that leverages existing security cameras to specifically monitor for and alert security officials to only brandished firearms.

Investments in regional transit service would create 13-times the return in value in household and travel times savings, according to new research made public today at the Chicago Transit Board of Directors’ monthly meeting.

CTA is the best travel option to get around town. Customers can save money by purchasing an unlimited rides pass, either the 1-Day ($5) – far more economical and convenient than the price of gas and parking - or the 3-Day ($15) pass – a real budget-saving move.

Overnight Work Construction lot east of 5343 N. Broadway (Jewel-Osco) for Material Delivery & Crane Lifts.

As part of ongoing efforts to provide riders with a modern transit riding experience, the Chicago Transit Authority (CTA) today announced the awarding of project stipends of $55,000 each for two vendors selected to provide digital bus stop sign solutions for testing under the new Innovation Studio.

Notice is hereby given that the Chicago Transit Authority (CTA) Board desires public comment before it considers an ordinance to adopt the Proposed 2025-2029 Capital Program of Projects, 2025 Operating Budget and Program and the Financial Plan for 2026 and 2027.

Choose CTA as the best transit option to get around the city. Customers can save money by purchasing an unlimited rides pass, either the 1-Day ($5) – far more economical and convenient than the price of gas and parking - or the 3-Day ($15) pass – a real budget-saving move.

(Mon, Feb 19 2024 to TBD) The west entrance to the Harlem (O’Hare branch) Blue Line station on Higgins Avenue and the adjacent Park and Ride lot will temporarily close.

(Fri, Jul 28 2023 10:00 PM to TBD) West platform at Wilson is temporarily closed. Board/exit all trains on the east platform.

(Fri, Jul 28 2023 10:00 PM to TBD) The temporary Argyle station on Argyle St is closed and a new temp Argyle station open 1-2 blks north, with staffed entrances on Foster Ave and Winona St.

(Fri, Jul 28 2023 10:00 PM to TBD) Temp Bryn Mawr stn entrances on B'way & Bryn Mawr Av closed; new temp Bryn Mawr stn open 75ft east of old stn under viaduct. Only 95th-bnd srvc at new temp stn.

(Tue, Oct 10 2023 to TBD) #1 buses will no longer start or end their trips at Union Station (Adams/Canal). Trips begin/end at Desplaines/Harrison. Boarding at Union Station is unchanged.

(Tue, Oct 10 2023 to TBD) #121 buses will no longer board on Jackson west of Canal (Stop A). Board buses in the Union Station Transit Center, just south of the current stop, at Stop C.

(Tue, Jul 2 2024 9:00 AM to TBD) The WB #152 stop on the SW corner at Addison/Lincoln will be temp discontinued. For WB svc, board/exit at Addison/Paulina or the Addison Brown Line station.

(Fri, Jun 28 2024 11:00 AM to TBD) The WB #77 stop on the NW corner at Racine/Belmont will be temporarily discontinued. For WB #77 svc, board/exit at Lakewood or Seminary.

(Mon, Oct 28 2024 9:00 AM to TBD) The WB #20 bus stop on the northeast corner on Madison/Western will be eliminated. A new WB bus stop will be added on the northwest corner at Maddison/Western.

(Sun, May 16 2021 12:01 AM to TBD) Eastbound and westbound 81 Lawrence bus stops at the closed Lawrence Red Line station are temporarily discontinued.

(Sun, May 16 2021 12:01 AM to TBD) 81 Lawrence: Westbound stop temporarily added on northwest corner at Wilson/Clark. Eastbound stop temporarily added on southwest corner at Wilson/Clark.

(Mon, Mar 25 2024 9:00 AM to TBD) The SB #22 and #24 bus stop on the SW corner at Clark/Lake will be temporarily discontinued.

(Wed, Dec 27 2023 9:00 AM to Fri, Nov 29 2024) The EB #12, #18, and #N62 bus stop at 327 W Roosevelt will be temporarily discontinued. For EB svc, use either Roosevelt/Delano or Roosevelt/Canal.

Even if you don't own stocks, there are a lot of reasons to care about investing. We meet some of the folks left out of the stock market who deploy sophisticated economic thinking, even creating their own alternate financial systems. Our professors help us understand how consumption smoothing and life-cycle hypothesis apply to personal finance. And we meet the creator of the 401(k). | Watch this Tik Tok to learn more and subscribe to our weekly newsletter here.

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It's Stacey vs Greg in a face off on the future of the office. Each takes a side, armed with studies, historical examples, theories on efficiency and happiness and from their closet studios, they bring their indicators for the future of the office. | Subscribe to our weekly newsletter here. And our daily podcast The Indicator hosted by Stacey here.

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COVID-19 prompted the quickest vaccine development in history. An inside look at how the government and pharmaceutical companies joined forces to make it happen.

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Nick and Robert head to the world's largest Christmas tree auction with $1,000 and a truck. And get schooled in the tree market. | Subscribe to our weekly newsletter here.

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While on the brink of extinction in the 1970s, manatees found sanctuary in the warm waters of Florida power plants. Now, they're hooked on fossil fuels. | Subscribe to our weekly newsletter here.

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We got our hands on the long-lost "Inflation" song, and now it's time to put it out into the world. So, we started a record label, and we're diving into the music business to try and make a hit.

This is part two of the Planet Money Records series. Here's part one and part three.

Update: We now have merch! We released a line of Inflation song gear — including a limited edition vinyl record; a colorful, neon hoodie; and 70s-inspired stickers. You can find it here: n.pr/shopplanetmoney.

Listen to "Inflation" on Apple Music, Spotify, YouTube Music, Tidal, Amazon Music & Pandora.

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Monopoly is one of the best-selling board games in history.

The game's staying power may in part be because of strong American lore — the idea that anyone, with just a little bit of cash, can rise from rags to riches. Mary Pilon, author of The Monopolists: Obsession, Fury, and the Scandal Behind the World's Favorite Board Game.
But there's another origin story – a very different one that promotes a very different image of capitalism. (And with two sets of starkly different rules.) That story shows how a critique of capitalism grew from a seed of an idea in a rebellious young woman's mind into a game legendary for its celebration of wealth at all costs.

This episode was made in collaboration with NPR's Throughline. For more about the origin story of Monopoly, listen to their original episode Do Not Pass Go.

This episode was produced by Emma Peaslee, mastered by Natasha Branch, and edited by Jess Jiang.

The Throughline episode was produced by Rund Abdelfatah, Ramtin Arablouei, Lawrence Wu, Laine Kaplan-Levenson, Julie Caine, Victor Yvellez, Anya Steinberg, Yolanda Sangweni, Casey Miner, Cristina Kim, Devin Katayama, and Amiri Tulloch. It was fact-checked by Kevin Volkl and mixed by Josh Newell.

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Predicting the future of the economy is always a dicey proposition. That is especially true after more than three years of pandemic-related economic weirdness. No one quite knows what will happen next.

Will the Fed be able to pull off a soft landing and bring down inflation without causing either a recession or a big jump in unemployment? Or will we end up with a hard landing, in which inflation comes down, but at the price of the country's economic health? Or, a third possibility, will the Fed not successfully bring inflation down at all?

On today's show, three economic experts explain what they look for when trying to make predictions about what might come next for the U.S. economy. And how those indicators lead them to very different conclusions. We will also consult a tarot card reader...to see if her reading of the future can help us know which outcome is the most likely.

This episode was hosted by Keith Romer, Sarah Gonzalez, and Jeff Guo. It was produced by Sam Yellowhorse Kesler and edited by Jess Jiang. It was engineered by Kwesi Lee with help from Maggie Luthar and fact-checked by Sierra Juarez. Alex Goldmark is our Executive Producer.

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How do you get the best deal? How do you know you're getting the best deal? Whether you're talking down the price of a car or talking up your salary, you don't have to be a jerk to get what you want. Negotiations can be win-win – if you know what to ask for and how to grow the pie.

We have three stories in today's episode about how to negotiate tactically. First, a hostage negotiator tries to buy a car. Will he get far? Then, one man's encounter at the airline ticket booth may inform how you respond to your next job offer. Finally, how to avoid a food fight and make a deal that benefits everybody.

We'll learn about something called BATNA, or best alternative to a negotiated agreement, which can tell you when to stand firm and when to walk away. We'll find out how to shift our thinking about what success can look like in a negotiation, and shift your counterpart's thinking too.

Come learn the techniques of expert negotiators in the penultimate episode of Planet Money Summer School, MBA edition. Next week: Graduation! So, you have one week to negotiate the cost of your cap and gown.

Our Summer School series is hosted by Robert Smith and produced by Max Freedman. Our project manager is Julia Carney. This episode was edited by our executive producer, Alex Goldmark, and engineered by James Willetts. The show was fact-checked by Sierra Juarez.

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When a group of amateur investors rallied around the stock for GameStop back in 2021, the story blew up the internet. News outlets around the world, including us here at Planet Money, rushed in to explain why the stock for this retail video game company was suddenly skyrocketing, at times by as much as 1700% in value, and what that meant for the rest of us.

When movie producer Aaron Ryder saw the GameStop story — an army of scrappy underdogs, banding together to strike back against a financial system they felt was rigged against them — he knew it had the makings for a great movie. The only problem: so did a bunch of other movie producers and Hollywood studios. So Aaron found himself in the middle of a fast and furious race to make the first Game Stop movie.

On today's show, one producer's quest to claim the hottest ticket in Tinseltown and the whole hidden machinery dedicated to turning a news story into box office gold. You'll never read the word 'based on a true story' the same way again.

Today's episode was reported and hosted by Alexi Horowitz-Ghazi. It was produced by Willa Rubin, edited by Jess Jiang, engineered by James Willetts, and fact-checked by Cooper Katz McKim and James Sneed. Alex Goldmark is our executive producer.

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Ba-dee-yah! Say do you remember? Ba-dee-yah! Questions in September!

That's right - it's time for Listener Questions!

Every so often, we like to hear from listeners about what's on their minds, and we try to get to the bottom of their economic mysteries. On today's show, we have questions like:

Why is September historically the worst month for the stock market?
How did the Bass Pro Shops hat get so popular in Ecuador?
Are casinos banks?
What is the Federal Reserve's new plan to make bank transfers faster?

Today's show was hosted by Sarah Gonzalez and produced by James Sneed. The audio engineer for this episode was Josephine Nyounai. It was fact checked by Sierra Juarez and edited by Dave Blanchard. Alex Goldmark is our executive producer.

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*Note: This episode originally ran in 2020*

'Tis the season for Americans to head out in droves and bring home a freshly-cut Christmas tree. But decorative evergreens don't just magically show up on corner lots, waiting to find a home in your living room. There are a bunch of fascinating steps that determine exactly how many Christmas trees get sold, and how expensive they are.

Today on the show, we visit the world's largest auction of Christmas trees — and then see how much green New Yorkers are willing to throw down for some greenery. It's a story where snow-dusted Yuletide dreams meet the hard reality of supply and demand. We've got market theory, a thousand dollars in cash, and a "decent sized truck"... anything could happen.

This episode was produced by James Sneed. It was edited by Bryant Urstadt. It was engineered by Gilly Moon. Alex Goldmark is Planet Money's executive producer.

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When you think of a potato, one state probably comes to mind: Idaho. But for much of American history, Maine was home to the nation's largest potato crop.

That status had changed by the 1970s, with the West growing more and more of the nation's potatoes. But Maine still had one distinct advantage: A privileged position in the commodities market. The New York Mercantile Exchange, one of the largest such marketplaces in the country, exclusively dealt in Maine potatoes. And two deep-pocketed Western potato kingpins weren't happy about it.

So the Westerners waged what's now called the Maine Potato War of 1976. Their battlefield was the futures market: A special type of marketplace, made up of hordes of screaming traders, where potatoes can be bought and sold before they're even planted.

The Westerners did something so bold – and so unexpected – that it brought not only the potato market, but the entire New York commodities exchange, to its knees.

Today on the show, how a war waged through futures contracts influenced the kind of potatoes we eat.

This episode was hosted by Dylan Sloan and Nick Fountain. This episode was produced by Sam Yellowhorse Kesler with help from Emma Peaslee. It was edited by Molly Messick, engineered by Valentina Rodríguez Sánchez, and fact checked by Sierra Juarez. Our executive producer is Alex Goldmark.

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On today's episode, we have three big economic ideas for your consideration – ideas that could potentially improve the economy and make us more efficient.

First, what if we ban left turns on roads? Then, what if we gave every new baby ... a trust fund? And lastly, what if we completely got rid of U.S. congressional districts?

That's all on today's episode.

This show was hosted by Sarah Gonzalez. It was produced by Willa Rubin and Emma Peaslee with help from Sam Yellowhorse Kesler. It was edited by Dave Blanchard and engineered by Robert Rodriguez. It was fact-checked by Sierra Juarez. Alex Goldmark is Planet Money's executive producer.

Help support Planet Money and get bonus episodes by subscribing to Planet Money+ in Apple Podcasts or at plus.npr.org/planetmoney.

Always free at these links: Apple Podcasts, Spotify, Google Podcasts, the NPR app or anywhere you get podcasts.

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The Genco Picardy is not an American ship. It doesn't pay U.S. taxes, none of its crew are U.S. nationals, and when it sailed through the Red Sea last month, it wasn't carrying cargo to or from an American port.

But when the Houthis, a tribal militant group from Yemen, attacked the ship, the crew called the U.S. Navy. That same day, the Navy fired missiles at Houthi sites.

On today's show: How did protecting the safe passage of other countries' ships in the Red Sea become a job for the U.S. military? It goes back to an idea called Freedom of the Seas, an idea that started out as an abstract pipe dream when it was coined in the early 1600s – but has become a pillar of the global economy.

This episode was hosted by Alex Mayyasi and Nick Fountain. It was produced by Sam Yellowhorse Kesler, edited by Molly Messick, fact-checked by Sierra Juarez, and engineered by Valentina Rodríguez Sánchez, with help from Maggie Luthar. Alex Goldmark is Planet Money's executive producer.

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