than Far Fewer Than Twenty-Four Things - Thing Three By johnfinnemore.blogspot.com Published On :: Sun, 03 Dec 2023 23:50:00 +0000 Alt Text. A blue man with a long neck appears sceptical about something. Full Article
than More Things Than None - One of Them By johnfinnemore.blogspot.com Published On :: Tue, 19 Dec 2023 23:55:00 +0000 Alt text: poire à la éléphant Full Article
than Right now, the Sun is far more active than predicted – and small satellites are paying the price - The Conversation By news.google.com Published On :: Tue, 12 Nov 2024 03:03:00 GMT Right now, the Sun is far more active than predicted – and small satellites are paying the price The ConversationUnpredictable Solar Activity Sends Satellites Plummeting to Earth ScienceAlert Full Article
than Wages growth slows faster than expected but still exceeds inflation - ABC News By news.google.com Published On :: Wed, 13 Nov 2024 00:47:47 GMT Wages growth slows faster than expected but still exceeds inflation ABC NewsReal wages are growing at highest rate since 2020. But it’s unlikely to last Sydney Morning HeraldSBS On the Money: Wages growth slows but real wages turn positive SBS News Full Article
than Kanguva Box Office Day 1 Advance Sales: 568% Higher Than Suriya’s Last Release ET In USA, Selling 5,460 Tix/Hr In India! - Koimoi By news.google.com Published On :: Tue, 12 Nov 2024 12:24:51 GMT Kanguva Box Office Day 1 Advance Sales: 568% Higher Than Suriya’s Last Release ET In USA, Selling 5,460 Tix/Hr In India! KoimoiKanguva morning show: Tamilians miffed as other states get earlier shows for Suriya, Bobby Deol's film Hindustan Times5 Reasons To Watch Suriya and Bobby Deol Starrer 'Kanguva' In Theatres Zee NewsKanguva’s second half to be very crisp 123teluguKanguva advance booking: Suriya's film earns over Rs 4 crore ahead of release India Today Full Article
than THANK GOD IT'S FRIDAY By cheezburger.com Published On :: Wed, 25 Jul 2012 18:00:00 -0700 THANK GOD IT'S FRIDAY bye mom. Gonna psend the weekend over with some college friends Full Article hilarious mom
than As today’s homes burn faster than ever, this year’s Fire Prevention Week campaign presents critical home escape planning and practice messages By www.nfpa.org Published On :: 27 Sep2017 19:37:24 GMT Knowing that today’s homes burn faster than ever, the National Fire Protection Association (NFPA) announced “Every Second Counts: Plan Two Ways Out” as the official theme for this year’s Fire Prevention Week campaign, October 8-14, 2017. Experts say you may have as little as two minutes (or even less) to safely escape a typical home fire from the time the smoke alarm sounds. Full Article
than Big business is better than you think (rooftops) By biztoc.com Published On :: Wed, 13 Nov 2024 06:18:35 GMT We characterize optimal product market policy in an unequal economy in which firm ownership is concentrated and markups increase with firm market shares. We study the problem of a utilitarian regulator who designs revenue-neutral interventions in the product market. We show that optimal policy… Full Article
than teardown: the SSD module is proprietary but replaceable, modular front ports, and the M4 Pro model has a beefier cooling rig than the M4 model By biztoc.com Published On :: Wed, 13 Nov 2024 06:40:32 GMT It shouldn’t be a big story that a desktop computer has upgradeable internal storage, but with Apple’s cute new 2024 Mac mini, that’s exactly where we are. It’s possible to pop the SSD out after removing a screw, and then switch in a bigger one. We didn’t run into the software blocks we saw in the… Full Article
than Ford is slashing the working hours of some of its German factory employees amid what it calls a 'significantly lower than expected' demand for its EVs By biztoc.com Published On :: Wed, 13 Nov 2024 07:01:53 GMT Ford is getting its workers in Cologne, Germany, to work fewer hours. The carmaker said a "lower than expected demand for electric vehicles" brought on the shift. The carmaker has more than 4,000 employees at its Cologne plant. Ford is slashing the work hours of its manufacturing plant workers in… Full Article
than Stamford Bridge: More than a Stadium By www.chelseafcblog.com Published On :: Sat, 27 Jan 2024 16:01:58 +0000 Welcome to the heart and soul of Chelsea Football Club – Stamford Bridge. This revered stadium stands not only as.. The post Stamford Bridge: More than a Stadium appeared first on Chelsea FC Blog. Full Article Feature
than It's Going To Be A Very Special Jesse Watters Thanksgiving By crooksandliars.com Published On :: Tue, 12 Nov 2024 11:04:00 +0000 Jesse Watters' mother, Anne Purvis, was a child psychologist. His dad, Stephen Hapgood Watters, was a teacher. Both parents came from a long line of achievers, and sent him to Penn Charter, a very liberal private Quaker school here in Philadelphia. Despite his accomplished parents and his education, look how he turned out. Every time he shows up on Twitter, I comment, "Your mother only talks to you so she can see her grandchildren." Sounds like I was right, because Jesse's mother has disinvited him from the family Thanksgiving this year. Something about "scheduling." But she told him he could come the next day for leftovers. He said no thanks, he would be at Best Buy. Understand, this isn't just a difference of opinion. Jesse Watters is a horrible person who lies and distorts in ways that harm our country. Time for karma, Jesse, you nasty piece of work. Guess you thought you got away with it, huh? After all, you're rich and famous! Well, your own family doesn't want to be around you on the holiday that's all about family. And your mom's bitten her tongue long enough.read more Full Article Jesse Watters Thanksgiving
than It's Worse Than We Thought! By cheezburger.com Published On :: Mon, 07 Nov 2011 23:28:42 -0800 We're gonna need a bigger hankie! Full Article funny Photo
than Scientific Replication is Harder Than YouThink -and Can Be Hilarious By www.neatorama.com Published On :: Mon, 11 Nov 2024 06:08:19 -0800 Science experiments are not considered completely valid unless they can be replicated. Replicating an experiment is pretty much impossible unless you've been steeped in the various factors of scientific theory. And even if you are thoroughly trained in those factors, it's easy to lose track when you're doing a casual experiment at home. That goes double when your aim is to debunk something that you find obviously wrong. Sage the Bad Naturalist jumped into such a debunking experiment with both feet, and then got entangled in them. She spent an entire year trying to replicate a dubious TikTok, which turned into an embarrassing adventure in how not to do science. But negative results are still results, and the goal of science is always to learn something. She bravely admits all the things she did wrong, because scientists have to have humility to be accepted. What's funniest is how many things went wrong, and how they all piled up to the end. What she ended up with is an amusing and rather charming video on the dangers of throwing your heart (and time) into debunking something you saw on the internet. -via Metafilter Full Article
than Our ancestor Lucy may have used tools more than 3 million years ago By www.livescience.com Published On :: Tue, 12 Nov 2024 17:29:35 +0000 An analysis looking at the hand bones of australopithecines, apes and humans reveals that tool use likely evolved before the Homo genus arose. Full Article Archaeology
than Wk3/4: Better late than dead By www.aquarionics.com Published On :: Sun, 24 Jan 2021 22:52:18 +0000 The difficulty of this weeknotes things is that entire weeks can go by without anything interesting happening. That’s… Full Article Uncategorized
than Election Officials Are Prepared for a Lot More Than You Might Think By catless.ncl.ac.uk Published On :: Full Article
than October 2024 Membership Drive: Thanks for your Support By archiveofourown.org Published On :: Mon, 21 Oct 2024 00:01:34 +0000 The Organization for Transformative Works's October membership drive is over and we are delighted to say that we are finishing with a total of $214,698.86 raised. We are particularly pleased that 6020 donors chose to either take up or renew OTW membership with their donation, far exceeding our goal of 4,500 members.These donations came from 6,955 people in 86 countries: thank you to every single one of you, as well as to all of you who posted and shared the news about the drive! The OTW would not exist without its users all around the world, and your continued support for us is our absolute pride and joy! We are so glad to know that our ongoing mission to support, protect, and provide access to the history of fanworks and fan culture continues to resonate with the people that matter most of all: the fans themselves.If you were intending to donate or join and haven't yet done so, don't worry! The OTW accepts donations year-round, and you can always choose to become a member with a donation of US$10 or more. Memberships run for one calendar year from the date of your donation. If you donate now, you'll be able to vote in next year's OTW Board election, which will take place in August 2025. Our exclusive thank-you gifts are also available whenever you donate! The Organization for Transformative Works is the non-profit parent organization of multiple projects including Archive of Our Own, Fanlore, Open Doors, Transformative Works and Cultures, and OTW Legal Advocacy. We are a fan-run, entirely donor-supported organization staffed by volunteers. Find out more about us on our website. Full Article
than University Holiday - Thanksgiving By www.princeton.edu Published On :: Thu, 28 Nov 2024 00:00:00 -0500 Full Article
than Community Thanksgiving Service By www.princeton.edu Published On :: Mon, 25 Nov 2024 19:00:00 -0500 All are welcome to this treasured annual community gathering, the Interfaith Thanksgiving Worship Service, in the University Chapel. Sponsored by Princeton University’s Office of Religious Life and the Princeton Clergy Association. Full Article
than 5 Times More Than 1BN People Watched the Same Event By www.star2.org Published On :: Sun, 29 Jan 2023 07:23:23 +0000 For most of us, even understanding what one billion really means is quite mind-boggling. Once you start getting to numbers that big it becomes hard to comprehend what the number really means and how that relates to real life. As such, the thought of 1 billion people all sitting at home at the same time ... Read more The post 5 Times More Than 1BN People Watched the Same Event appeared first on Star Two. Full Article Entertainment Barak Obama’s Inauguration Event Live 8 Live Aid Live in Berli Live music events Prince Harry
than Thanking God in the darkest times By www.womenoftheelca.org Published On :: Mon, 11 Nov 2024 07:00:57 +0000 “Now thank we all our God, with hearts and hands and voices, who wondrous things has done, in whom this Read More The post Thanking God in the darkest times appeared first on Women of the ELCA. Full Article Daily Grace
than Jonathan Swift By encyclopedia2.thefreedictionary.com Published On :: Tue, 12 Nov 2024 05:00:00 GMT There's none so blind as they that won't see. Full Article
than Thank You For Being With Us! By www.rssground.com Published On :: Thu, 22 Nov 2018 11:23:09 +0000 From the very first days, RSS Ground was built based on our users’ needs, suggestions and requests. Our users is our main driving force, the core of RSS Ground. And for the majority of our users, it’s a Thanksgiving this week. We always prepare a gift for Thanksgiving and this year we will continue this […] The post Thank You For Being With Us! appeared first on RSSground.com. Full Article RSS Ground News
than Thank You, Dear Friends! By www.rssground.com Published On :: Thu, 28 Nov 2019 16:35:22 +0000 We sincerely thank you for your contribution to the development of the service. We appreciate your feedback and cooperation. The post Thank You, Dear Friends! appeared first on RSSground.com. Full Article RSS Ground News change log new features service updates thanksgiving2019
than Happy Thanksgiving 2020 By www.rssground.com Published On :: Thu, 26 Nov 2020 08:56:02 +0000 Here comes another year of giving thanks to all our dear customers! Happy Thanksgiving to everyone celebrating. May you enjoy this wonderful occasion and have lots of fun in the whole year ahead. We will do our best to keep RSS Ground on the highest level and continue developing it according to your needs. Thank […] The post Happy Thanksgiving 2020 appeared first on RSSground.com. Full Article RSS Ground News holiday Thanksgiving
than Happy Thanksgiving and Black Friday Deal By www.rssground.com Published On :: Tue, 23 Nov 2021 18:44:18 +0000 We are taking this opportunity to say Thank You! We can’t express how much we appreciate you being a part of RSS Ground family. We hope our unique tools will continue to be useful to you for years to come. We usually never do this, but this time we would like to show our token […] The post Happy Thanksgiving and Black Friday Deal appeared first on RSSground.com. Full Article RSS Ground News Black Friday Deal discount Happy Holidays
than Happy Thanksgiving! By www.rssground.com Published On :: Thu, 24 Nov 2022 14:34:51 +0000 Traditionally, end of November is the time to be thankful, a time to remember and to embrace those who enrich our lives. Thanks to your active participation in our development process we continue to grow RSS Ground service. This year we have added several powerful tools based on your feedback: Telegram Feeds and automated Poster, […] The post Happy Thanksgiving! appeared first on RSSground.com. Full Article RSS Ground News Thanksgiving upcoming updates vote
than A Time for Gratitude: Wishing Our Beloved RSS Ground Community a Happy Thanksgiving! By www.rssground.com Published On :: Wed, 22 Nov 2023 22:16:25 +0000 Dear RSS Ground Family, As the golden leaves of autumn usher in a season of warmth and gratitude, we pause to reflect on the journey we’ve shared. Thanksgiving isn’t just a holiday—it’s a heartfelt reminder of the importance of connection, community, and the spirit of giving thanks. Today, we extend our deepest appreciation to you, […] The post A Time for Gratitude: Wishing Our Beloved RSS Ground Community a Happy Thanksgiving! appeared first on RSSground.com. Full Article RSS Ground News
than Đức nói với Bộ trưởng Lương Tam Quang: 'Không được tái diễn vụ việc tương tự Trịnh Xuân Thanh' By www.bbc.com Published On :: Fri, 08 Nov 2024 23:47:46 GMT Các quan chức an ninh Đức nói với Bộ trưởng Công an Lương Tam Quang rằng những vụ việc như vụ bắt cóc Trịnh Xuân Thanh "không được tái diễn". Full Article
than Ông Trump sẽ thực hiện cuộc thanh trừng trong Bộ Quốc phòng Mỹ? By www.bbc.com Published On :: Tue, 12 Nov 2024 03:40:29 GMT Các quan chức Bộ Quốc phòng Mỹ lo lắng Tổng thống đắc cử Donald Trump sẽ thực hiện cuộc thanh trừng bên trong bộ này. Full Article
than New Thermal Material Provides 72% Better Cooling Than Conventional Paste By hardware.slashdot.org Published On :: 2024-11-13T01:30:00+00:00 "Researchers at the University of Texas have unveiled a new thermal interface material that could revolutionize cooling, outperforming top liquid metal solutions by up to 72% in heat dissipation," writes Slashdot reader jjslash. "This breakthrough not only improves energy efficiency but also enables higher-density data center setups, cutting cooling costs and energy usage significantly." TechSpot reports: Thanks to a mechanochemically engineered combination of the liquid metal alloy Galinstan and ceramic aluminum nitride, this thermal interface material, or TIM, outperformed the best commercial liquid metal cooling products by a staggering 56-72% in lab tests. It allowed dissipation of up to 2,760 watts of heat from just a 16 square centimeter area. The material pulls this off by bridging the gap between the theoretical heat transfer limits of these materials and what's achieved in real products. Through mechanochemistry, the liquid metal and ceramic ingredients are mixed in an extremely controlled way, creating gradient interfaces that heat can flow across much more easily. Beyond just being better at cooling, the researchers claim that the higher performance reduces the energy needed to run cooling pumps and fans by up to 65%. It also unlocks the ability to cram more heat-generating processors into the same space without overheating issues. [...] As for how you can get your hands on the material: it's yet to make it out of the labs. The UT team has so far only tested it successfully at small scales but is now working on producing larger batches to put through real-world trials with data center partners. The material has been detailed in a paper published in the journal Nature Nanotechnology. Read more of this story at Slashdot. Full Article
than Trump is far, far, far better than Harris on corporate taxes By quinhillyer.com Published On :: Tue, 29 Oct 2024 00:40:42 +0000 (Official Washington Examiner editorial, October 28) On corporate tax rates, former President Donald Trump’s position is demonstrably superior to Vice President Kamala Harris’s demagoguery. As part of her tiresome schtick […] The post Trump is far, far, far better than Harris on corporate taxes appeared first on Quin Hillyer. Full Article National Politics
than Corruption review finds 'red flags' in more than 130 Covid contracts By www.bbc.com Published On :: Mon, 09 Sep 2024 00:04:10 GMT An anti-corruption charity finds significant concerns in £15.3bn worth of contracts awarded during the pandemic. Full Article
than Why Norris wants Silverstone win more than any other By www.bbc.com Published On :: Thu, 04 Jul 2024 17:02:56 GMT McLaren’s Lando Norris explains why he wants to win the British Grand Prix more than any other race in Formula 1. Full Article
than velocityconf: @rkustner Congrats, thank you, and good luck! By twitter.com Published On :: Wed, 15 May 2013 17:02:38 +0000 velocityconf: @rkustner Congrats, thank you, and good luck! Full Article
than velocityconf: What Is the Risk That Amazon Will Go Down (Again)? http://t.co/DgnfQynjcM Thank you @bergstrom_johan for the awesome #velocityconf post. By twitter.com Published On :: Thu, 30 May 2013 19:02:44 +0000 velocityconf: What Is the Risk That Amazon Will Go Down (Again)? http://t.co/DgnfQynjcM Thank you @bergstrom_johan for the awesome #velocityconf post. Full Article
than My Faith in Nerds: Stronger Than Any Gelatinous Cube By www.43folders.com Published On :: Fri, 10 Sep 2010 20:01:57 +0000 dConstruct 2010: Merlin Mann - "Kerning, Orgasms & Those Goddamned Japanese Toothpicks" (NSFW) ME - Kerning, Orgasms And Those Goddamned Japanese Toothpicks on Huffduffer Download the audio | Huffduff it Let's be honest. I don't go...mmmm...places very often. I sit in this chair. I go to the Safeway with my daughter. Sometimes, I take the train downtown to get a haircut. I check the mail. But, by and large, like most nerds, I'm without question, a bit of a shut-in. Which makes it more than a little ironic that my first trip off the North American continent brought me all the way to Brighton, England's wonderful dConstruct Conference. Which wonderful conference placed me inside a very royal complex, alone on a very large stage, 90 seconds after being informed I'd better be entertaining, because I'd be conducting my oration on the same spot where, a scant 36 years earlier, ABBA had become international stars by singing an up-tempo number about giving up. So, y'know. No pressure. Commanded to this location by two of my web heroes, I was told I could speak about whatever I wanted. So, wow, to quote the ladies of ABBA, how could I ever refuse? Thus, I stood on that stage for over 35 minutes, rambling to 800 talented, creative people about Dungeons & Dragons, japanese toothpicks, torrenting Photoshop, as well as what I used to find myself doing after a long evening of shooting mutants in Stargate.1 But, mostly? Yes. Mostly, I stood on a stage thousands of miles from the chair from which I barely move, and I told a lot of really smart people that they were nerds. I also told them they should get out more. I swear: it made sense at the time. Some Serious Talent My talk about the challenges and opportunities of being a giant nerd seemed well received. Honestly, I'm very happy with how it turned out. But--oh, brother--was I ever up against some heavy hitters. Serious Lou Gehrig shit. I'll leave it to other, more eloquent folks to tell you what a wonderful day this was. But I will very much suggest you learn this for yourself by listening to the audio of the fantastic talks. Because every one of them is a corker. Additionally, like I said, Tom Coates put on one of the loveliest slide decks it's ever been my pleasure to see (56MB PDF). Great speakers, great hosts, wonderful attendees (who aren't above buying a yank a pint [thanks, everybody]). And, Thanks, dConstruct I have to admit, I'm kind of over conferences as a thing, which makes it even more crazy when I go to one, and it blows me out of the water with the care and quality of the event, the speakers, and the attendees. dConstruct was absolutely one of those blown-out-of-the-water events. (photo: happy.apple) As I learned over and over again--yes, like me--these folks are nerds. But, brother are they ever talented nerds who care and care. Which I just love so much. I'll take a nerdy bunch of fontdorks and cellists over a splashy mega-conference full of VC pitches and skanks pushing free Red Bull anytime. Anytime. dConstruct was simply a top-notch operation from end-to-end, and I'm insanely grateful that I was invited to participate. Thanks, Clearleft. And, you, the reader? If you get the chance next time, go. Heck, I might even leave this chair and go there, myself. Maybe. I suppose when Dr. Who's over, I could just let these 20-sided dice decide for me. Lemme see...what's my Armor Class and Hit Points...? Listen for Yourself2 dConstruct Podcast MARTY NEUMEIER - The Designful Company The Designful Company on Huffduffer Download the audio | Huffduff it BRENDAN DAWES - Boil, Simmer, Reduce Boil, Simmer, Reduce on Huffduffer Download the audio | Huffduff it DAVID MCCANDLESS - Information Is Beautiful Information Is Beautiful on Huffduffer Download the audio | Huffduff it SAMANTHA WARREN - The Power and Beauty of Typography The Power and Beauty of Typography on Huffduffer Download the audio | Huffduff it JOHN GRUBER - The Auteur Theory Of Design The Auteur Theory Of Design on Huffduffer Download the audio | Huffduff it HANNAH DONOVAN - Jam Session: What Improvisation Can Teach Us About Design Jam Session: What Improvisation Can Teach Us About Design on Huffduffer Download the audio | Huffduff it JAMES BRIDLE - The Value Of Ruins The Value Of Ruins on Huffduffer Download the audio | Huffduff it TOM COATES - Everything The Network Touches Everything The Network Touches on Huffduffer Download the audio | Huffduff it Kerning, Orgasms And Those Goddamned Japanese Toothpicks ME - Kerning, Orgasms And Those Goddamned Japanese Toothpicks on Huffduffer Download the audio | Huffduff it Hint: Number Three. ↩ Code for these was stolen wholesale from the dConstruct site. Jeremy, et al - don't hesitate to tell me if that's a problem.Srsly. ↩ ”My Faith in Nerds: Stronger Than Any Gelatinous Cube” was written by Merlin Mann for 43Folders.com and was originally posted on September 10, 2010. Except as noted, it's ©2010 Merlin Mann and licensed for reuse under CC BY-NC-ND 3.0. "Why a footer?" Full Article dConstruct Geeks Knowledge Workers Nerds Speaking
than The REAL Harm Done By Calling Everyone You Don’t Like ‘Hitler’ Is BIGGER Than Lefties Think By clashdaily.com Published On :: Tue, 05 Nov 2024 11:18:25 +0000 There's a reason Hitler holds a special place of disgrace in public memory. He combined the ambition and destruction of Attila The Hun with the personal malice of a serial killer. The post The REAL Harm Done By Calling Everyone You Don’t Like ‘Hitler’ Is BIGGER Than Lefties Think appeared first on Clash Daily. Full Article Videos
than Trump Scores Three Big Wins Less Than One Day After The Election By clashdaily.com Published On :: Thu, 07 Nov 2024 10:00:34 +0000 While the rest of us were busy cheering (or crying) about the election results, the world kept turning and events continued to unfold at home and around the world. The post Trump Scores Three Big Wins Less Than One Day After The Election appeared first on Clash Daily. Full Article News Clash
than Fired FEMA Worker Reveals Discrimination Against Trump Supporters Was Even Worse Than First Reported By www.westernjournal.com Published On :: Tue, 12 Nov 2024 20:39:18 +0000 Just because you’re paranoid, it doesn’t mean you’re wrong. And for any supporters of President-elect Donald Trump who feel that they’ve been unfairly targeted by the government, but were summarily […] The post Fired FEMA Worker Reveals Discrimination Against Trump Supporters Was Even Worse Than First Reported appeared first on The Western Journal. Full Article Commentary Donald Trump Federal Emergency Management Agency Florida Liberalism Liberals Natural disasters North Carolina Republicans South Carolina Viral
than Preparation of fatty acid methyl esters and dimethylacetals from lipids with boron fluoride--methanol By www.jlr.org Published On :: 1964-10-01 William R. MorrisonOct 1, 1964; 5:600-608Articles Full Article
than Coronavirus and trade war pushing China to focus on fixing economy rather than leading world order By www.chathamhouse.org Published On :: Wed, 10 Jun 2020 08:49:06 +0000 Source The South China Morning Post URL https://www.scmp.com/comment/opinion/article/3087713/coronavirus-and-trade-war-p... Release date 08 June 2020 Expert Dr Yu Jie In the news type Op-ed Hide date on homepage Full Article
than The Election Proved Something Painful About Gen Z. It’s Worse Than We Thought. By www.yahoo.com Published On :: 2024-11-12T20:00:00Z Full Article
than Kinetic Analysis and Metabolism of Poly(Adenosine Diphosphate-Ribose) Polymerase-1-Targeted 18F-Fluorthanatrace PET in Breast Cancer By jnm.snmjournals.org Published On :: 2024-10-30T08:04:15-07:00 Visual Abstract Full Article
than Update on LIPID MAPS classification, nomenclature, and shorthand notation for MS-derived lipid structures By www.jlr.org Published On :: 2020-12-01 Gerhard LiebischDec 1, 2020; 61:1539-1555Special Report Full Article
than Problem Notes for SAS®9 - 46544: Store layout view has some areas displayed with black fill rather than gray in SAS® Retail Space Management By Published On :: Wed, 26 Aug 2020 16:14:45 EST In SAS Retail Space Management, it should be possible to click on any location object, then Show Properties, and change the location fill color. This can be done on the gray-filled objects. However, w Full Article RTLSPCMGT+SAS+Retail+Space+Management
than US adults are more likely to have poor health than those in 10 similar countries, survey finds By www.bmj.com Published On :: Wednesday, November 16, 2016 - 22:00 Full Article
than Tetracosahexaenoylethanolamide, a novel N-acylethanolamide, is elevated in ischemia and increases neuronal output [Research Articles] By www.jlr.org Published On :: 2020-11-01T00:05:43-07:00 N-acylethanolamines (NAEs) are endogenous lipid-signaling molecules derived from fatty acids that regulate numerous biological functions, including in the brain. Interestingly, NAEs are elevated in the absence of fatty acid amide hydrolase (FAAH) and following CO2-induced ischemia/hypercapnia, suggesting a neuroprotective response. Tetracosahexaenoic acid (THA) is a product and precursor to DHA; however, the NAE product, tetracosahexaenoylethanolamide (THEA), has never been reported. Presently, THEA was chemically synthesized as an authentic standard to confirm THEA presence in biological tissues. Whole brains were collected and analyzed for unesterified THA, total THA, and THEA in wild-type and FAAH-KO mice that were euthanized by either head-focused microwave fixation, CO2 + microwave, or CO2 only. PPAR activity by transient transfection assay and ex vivo neuronal output in medium spiny neurons (MSNs) of the nucleus accumbens by patch clamp electrophysiology were determined following THEA exposure. THEA in the wild-type mice was nearly doubled (P < 0.05) following ischemia/hypercapnia (CO2 euthanization) and up to 12 times higher (P < 0.001) in the FAAH-KO compared with wild-type. THEA did not increase (P > 0.05) transcriptional activity of PPARs relative to control, but 100 nM of THEA increased (P < 0.001) neuronal output in MSNs of the nucleus accumbens. Here were identify a novel NAE, THEA, in the brain that is elevated upon ischemia/hypercapnia and by KO of the FAAH enzyme. While THEA did not activate PPAR, it augmented the excitability of MSNs in the nucleus accumbens. Overall, our results suggest that THEA is a novel NAE that is produced in the brain upon ischemia/hypercapnia and regulates neuronal excitation. Full Article
than Update on LIPID MAPS classification, nomenclature, and shorthand notation for MS-derived lipid structures [Special Reports] By www.jlr.org Published On :: 2020-12-01T00:05:39-08:00 A comprehensive and standardized system to report lipid structures analyzed by MS is essential for the communication and storage of lipidomics data. Herein, an update on both the LIPID MAPS classification system and shorthand notation of lipid structures is presented for lipid categories Fatty Acyls (FA), Glycerolipids (GL), Glycerophospholipids (GP), Sphingolipids (SP), and Sterols (ST). With its major changes, i.e., annotation of ring double bond equivalents and number of oxygens, the updated shorthand notation facilitates reporting of newly delineated oxygenated lipid species as well. For standardized reporting in lipidomics, the hierarchical architecture of shorthand notation reflects the diverse structural resolution powers provided by mass spectrometric assays. Moreover, shorthand notation is expanded beyond mammalian phyla to lipids from plant and yeast phyla. Finally, annotation of atoms is included for the use of stable isotope-labeled compounds in metabolic labeling experiments or as internal standards. This update on lipid classification, nomenclature, and shorthand annotation for lipid mass spectra is considered a standard for lipid data presentation. Full Article
