Join us for our per- and polyfluoroalkyl substances webinar on Best Environmental Practices (BEP) for Textiles

This paper reviews and compares five case studies on quantification and economic valuation of benefits in cost-benefit analyses (CBAs) of regulating phthalates, mercury, PFOA (perfluoro-octanic acid) and its salts, NMP (1 methyl-2-pyrroloidine) and formaldehyde. The case studies had all been carried out as part of the SACAME project, and the purpose of the present paper is to draw out cross-cutting findings from these studies.

This document aims to assist government and industry assessors involved in the registration of microbial pesticides in the determination of whether microbial pesticides could be associated with known or as yet uncharacterised ‘new’ secondary metabolites. A background document that was also published as Annex to the main document aims to provide clarity on issues and terminology related to microbial secondary metabolites.

This document outlines various approaches and methodologies for the assessment of risks from combined exposures to multiple chemicals. The document draws from approaches and experience in the regulatory context, and presents elements to consider in the assessment.

The OECD releases a video tutorial on how to find GHS information in eChemPortal through the substance search and how to search by GHS classification. Currently 11 databases provide GHS information, independent of whether the classifications have undergone a review by a regulatory body or intergovernmental organisation or are based on self-classifications by the producers or importers.

The first report is a synthesis from a Workshop on Approaches to Support Substitution and Alternatives Assessment, which discussed approaches used to support alternative assessments and substitution. The second report is a Cross Country Analysis of Approaches to Support Alternatives Assessment and Substitution of Chemicals of Concern that describes a list of approaches developed across countries and by different stakeholders.

Today, OECD Council adopted the Recommendation on Countering the Illegal Trade of Pesticides to strengthen cooperation between countries and inspectors and identify illegal pesticides throughout their lifecycle with a Best Practice Guidance.

This report outlines the customisation opportunities for IUCLID version 6. It also gives an overview of what IUCLID offers to regulatory bodies and industry as a key application to record, store, maintain and exchange data on chemicals. IUCLID is used in a variety of countries and regulatory contexts, therefore the report describes to which extent it is customisable to facilitate the management of chemical data across these contexts.

On 11 February 2019, the OECD organised a webinar to learn and discuss new methodologies on liver models for induction, clearance and toxicity. The speakers presented the benefits compared to existing methods in place, the types of chemicals tested, the results obtained, the transferability and economic aspects for routine testing, and any known limitation to the technologies and their applications.

Nanomaterials have unique physical and chemical features. OECD's Decision Framework and Guiding Principles tools fill data gaps in the hazard characterisation by identifying the most useful parameters and best available methods for a given type of nanomaterial.

GHSTS is a standardised set of technical specifications for assembling electronic files for pesticide registration in a predefined manner. Once assembled according to the GHSTS, the dossier files can be transferred from a business to a regulatory authority and can be used in a regulatory process. Version 2.0 includes improved lifecycle management of documents over a series of submissions for one pesticide (or other) regulatory action.

Policy instruments can be applied to improve the sustainability of plastics, including regulations, market-based instruments, information and voluntary tools. The report reviews the use of these instruments, provides good practice examples, such as product taxes and charges, eco-design standards, extended producer responsibility and environmental product labels, as well as discussing opportunities for their future applications.

The purpose of this document is to give guidance to Receiving Authorities on the evaluation of the GLP compliance status of nonclinical safety studies submitted for regulatory purposes. This guidance does not address the scientific evaluation and interpretation of the submitted data or the risk assessment based on these data.

On Thursday 26 September 2019, the OECD discussed "Finding Alternatives to Per- and Polyfluoroalkyl Substances of Concern: A Difficult and Continuing Challenge" with the participation of W.L. Gore & Associates, Inc. Presenters shared efforts, successes and challenges in eliminating per and polyfluorinated chemicals of environmental concern from the life cycle of consumer products.

On 27 September 2019, Anne Gourmelon of the Environment Directorate presented an overview of the various alternative test methods developed as OECD Test Guidelines and relevant guidance material to address eye irritation and serious eye damage for hazard classification of chemicals.

A major fruit crop of temperate regions, APPLE is consumed worldwide as fresh fruit, juice and other food products. This consensus document provides science-based key insights for the regulatory assessment of the environmental safety of genetically-engineered products: taxonomy, reproductive biology, genetics, hybridisation and introgression, and ecology.

This document is intended to provide universal Guiding Principles that should be considered when developing or augmenting systematic approaches to Weight of Evidence (WoE) for chemical evaluation and Key Elements to formulating a systematic approach to WoE. The ultimate goal is to facilitate that regulators follow a consistent, clear and transparent delivery of evidence using the Principles and Elements described in this document.

United States recorded 1347318 Coronavirus Cases since the epidemic began, according to the World Health Organization (WHO). In addition, United States reported 78616 Coronavirus Deaths. This page includes a chart with historical data for the United States Coronavirus Cases.

United States recorded 80040 Coronavirus Deaths since the epidemic began, according to the World Health Organization (WHO). In addition, United States reported 1347318 Coronavirus Cases. This page includes a chart with historical data for the United States Coronavirus Deaths.

United States recorded 238080 Coronavirus Recovered since the epidemic began, according to the World Health Organization (WHO). In addition, United States reported 80040 Coronavirus Deaths. This page includes a chart with historical data for the United States Coronavirus Recovered.

Victor Erice is one of those rare film directors who show time passing apparently at its own pace

Three recent decisions have brought this issue into focus – and all three are lamentable and incoherent

There are profound reasons for studying the languages, literature and civilisations of the Greeks and Romans

This is about reminding ourselves that we are animals, not adjuncts to computer terminals

‘There is a unique beauty to this time of year. Everything looks ghostly in the dense, opaque air’

Feelings of shame, unlike other emotions, are difficult to hide

Perhaps a lot of rugby has always been prosaic but I struggle to recall such a dearth of poetry

The taming of the Tea Party leaves the GOP short on the ideological message the voters like

The defenestration of Cantor sends a message to the cosy world of party bigwigs and donors

People seem to resign themselves to innovations they considered dubious at the outset

Elected rulers use heavy-handed authority to prevent being toppled by swings in opinion

A website’s faults do not absolve it from dealing fairly with users

From abortion to gay rights, he is unorthodox on Republican ‘values’, writes Christopher Caldwell

Whatever his short-term plans, Trump wants a radical tightening of US border policy

Sadoun: “This is how I work: I go fast, I take risk, I learn, I correct if it’s not good”

The deal with Luxottica, worth €50bn, makes up for missed opportunities

How the former banker stumbled into the top job eight years ago — and never left

The sports marketing and agency boss explains why the City of Angels is ready to play host

How the ride-hailing chief’s good-guy image is paying off

The entertainment boss runs his online streaming company like a champion sports team

The travel company CEO sees voice search as the next opportunity for growth

The son of a towering industry figure is building his own empire

After a stormy summer, the chief is shaking up the world’s biggest shipping company

How the property dynamo went from a milk round to becoming a self-made billionaire

The man who invented China’s Singles Day eyes opportunity offline

Europe’s biggest activist investor shakes up management teams to unlock hidden value

Can the sports car maker compete with Tesla as it moves into its territory?

In an industry obsessed with algorithms, the media boss is focusing on quality

The Japanese trading house trusts its history of investment to create new lines of business

In a male-dominated industry, the executive says she has not been held back