for

2014 Evidence-Based Guideline for the Management of High Blood Pressure in Adults: Report From the Panel Members Appointed to the Eighth Joint National Committee (JNC 8)

Interview with Paul A. James, MD, author of 2014 Evidence-Based Guideline for the Management of High Blood Pressure in Adults: Report From the Panel Members Appointed to the Eighth Joint National Committee (JNC 8)




for

Cognitive Behavioral Therapy Plus Amitriptyline for Chronic Migraine in Children and Adolescents

Interview with Scott W. Powers, PhD, author of Cognitive Behavioral Therapy Plus Amitriptyline for Chronic Migraine in Children and Adolescents




for

Long-term Drug Treatment for Obesity: A Systematic and Clinical Review

Interview with Susan Z. Yanovski, MD, author of Long-term Drug Treatment for Obesity: A Systematic and Clinical Review




for

Associations of Housing Mobility Interventions for Children in High-Poverty Neighborhoods With Subsequent Mental Disorders During Adolescence

Interview with Ronald C. Kessler, PhD, author of Associations of Housing Mobility Interventions for Children in High-Poverty Neighborhoods With Subsequent Mental Disorders During Adolescence




for

Comparison of 2 Transvaginal Surgical Approaches and Perioperative Behavioral Therapy for Apical Vaginal Prolapse

Interview with Matthew D. Barber, MD, MHS, author of Comparison of 2 Transvaginal Surgical Approaches and Perioperative Behavioral Therapy for Apical Vaginal Prolapse




for

Screening for Prostate Cancer With the Prostate-Specific Antigen Test: A Review of Current Evidence

Interview with Michael J. Barry, MD, author of Screening for Prostate Cancer With the Prostate-Specific Antigen Test: A Review of Current Evidence




for

Web-Based Alcohol Screening and Brief Intervention for University Students: A Randomized Trial

Interview with Nicholas J. Horton, ScD, author of Web-Based Alcohol Screening and Brief Intervention for University Students: A Randomized Trial




for

Door-to-Needle Times for Tissue Plasminogen Activator Administration and Clinical Outcomes in Acute Ischemic Stroke Before and After a Quality Improvement Initiative

Interview with Gregg C. Fonarow, MD, author of Door-to-Needle Times for Tissue Plasminogen Activator Administration and Clinical Outcomes in Acute Ischemic Stroke Before and After a Quality Improvement Initiative




for

Association Between Intensification of Metformin Treatment With Insulin vs Sulfonylureas and Cardiovascular Events and All-Cause Mortality Among Patients With Diabetes

Interview with Christianne L. Roumie, MD, MPH, author of Association Between Intensification of Metformin Treatment With Insulin vs Sulfonylureas and Cardiovascular Events and All-Cause Mortality Among Patients With Diabetes




for

Nonmyeloablative HLA-Matched Sibling Allogeneic Hematopoietic Stem Cell Transplantation for Severe Sickle Cell Phenotype

Interview with John F. Tisdale, MD, author of Nonmyeloablative HLA-Matched Sibling Allogeneic Hematopoietic Stem Cell Transplantation for Severe Sickle Cell Phenotype




for

Sofosbuvir and Ribavirin for Hepatitis C in Patients With HIV Coinfection

Interview with Mark S. Sulkowski, MD, author of Sofosbuvir and Ribavirin for Hepatitis C in Patients With HIV Coinfection




for

Screening and Brief Intervention for Drug Use in Primary Care

Interview with Richard Saitz, MD, MPH, author of Screening and Brief Intervention for Drug Use in Primary Care




for

Collaborative Care for Adolescents With Depression in Primary Care

Interview with Laura P. Richardson, MD, MPH, author of Collaborative Care for Adolescents With Depression in Primary Care




for

Use of and Mortality After Bilateral Mastectomy Compared With Other Surgical Treatments for Breast Cancer in California, 1998-2011

Interview with Allison W. Kurian, MD, MSc, author of Use of and Mortality After Bilateral Mastectomy Compared With Other Surgical Treatments for Breast Cancer in California, 1998-2011




for

Effect of Enhanced Information, Values Clarification, and Removal of Financial Barriers on Use of Prenatal Genetic Testing

Interview with Miriam Kuppermann, PhD, MPH, author of Effect of Enhanced Information, Values Clarification, and Removal of Financial Barriers on Use of Prenatal Genetic Testing




for

Effect of a Postdischarge Virtual Ward on Readmission or Death for High-Risk Patients

Interview with Irfan A. Dhalla, MD, MSc, author of Effect of a Postdischarge Virtual Ward on Readmission or Death for High-Risk Patients




for

Acupuncture for Chronic Knee Pain: A Randomized Clinical Trial

Interview with Kim L. Bennell, PhD, author of Acupuncture for Chronic Knee Pain: A Randomized Clinical Trial




for

For-Profit Status and Clinical and Economic Outcomes

Interview with Ashish K. Jha, MD, MPH, author of Association Between Hospital Conversions to For-Profit Status and Clinical and Economic Outcomes




for

Frozen Fecal Microbiota for C difficile Infection

Interview with Ilan Youngster, MD, MMSc, author of Oral, Capsulized, Frozen Fecal Microbiota Transplantation for Relapsing Clostridium difficile Infection




for

Medical Liability and Reform

Interview with Michelle M. Mello, JD, PhD, MPhil, author of The Medical Liability Climate and Prospects for Reform




for

Resident Duty Hour Reforms and Patient Outcomes

Interview with Mitesh S. Patel, MD, MBA, MS, author of Association of the 2011 ACGME Resident Duty Hour Reforms With Mortality and Readmissions Among Hospitalized Medicare Patients




for

Hematopoietic Stem Cell Transplantation for Multiple Sclerosis

Interview with Richard K. Burt, MD, author of Association of Nonmyeloablative Hematopoietic Stem Cell Transplantation With Neurological Disability in Patients With Relapsing-Remitting Multiple Sclerosis




for

MR/Ultrasound Fusion Biopsy for Prostate Cancer

Interview with Peter A. Pinto, MD, author of Comparison of MR/Ultrasound Fusion-Guided Biopsy With Ultrasound-Guided Biopsy for the Diagnosis of Prostate Cancer




for

Varenicline for Smoking Cessation Through Smoking Reduction

Interview with Jon O. Ebbert, MD, MSc, author of Effect of Varenicline on Smoking Cessation Through Smoking Reduction




for

Corticosteroids for Severe Community-Acquired Pneumonia

Interview with Antoni Torres, MD, PhD, author of Effect of Corticosteroids on Treatment Failure Among Hospitalized Patients With Severe Community-Acquired Pneumonia and High Inflammatory Response: A Randomized Clinical Trial




for

Folic Acid for Stroke Prevention in Hypertension

Interview with Xiaobin Wang, MD, ScD, author of Efficacy of Folic Acid Therapy in Primary Prevention of Stroke Among Adults With Hypertension in China: The CSPPT Randomized Clinical Trial




for

Early Imaging for Back Pain in Older Adults

Interview with Jeffrey G. Jarvik, MD, MPH, author of Association of Early Imaging for Back Pain With Clinical Outcomes in Older Adults




for

Oral Insulin and Immune Responses in Children at Risk for Diabetes

Interview with Ezio Bonifacio, PhD, author of Effects of High-Dose Oral Insulin on Immune Responses in Children at High Risk for Type 1 Diabetes: The Pre-POINT Randomized Clinical Trial




for

ED-Initiated Treatment for Opioid Dependence

Interview with Gail D'Onofrio, MD, MS, author of Emergency Department-Initiated Buprenorphine/Naloxone Treatment for Opioid Dependence: A Randomized Clinical Trial




for

Nontoxigenic Clostridium difficile for Prevention of Recurrent Infection

Interview with Dale N. Gerding, MD, author of Administration of Spores of Nontoxigenic Clostridium difficile Strain M3 for Prevention of Recurrent C difficile Infection: A Randomized Clinical Trial




for

DCV/ASV/BCV for HCV Infection With Cirrhosis

Interview with Andrew J. Muir, MD, author of Daclatasvir in Combination With Asunaprevir and Beclabuvir for Hepatitis C Virus Genotype 1 Infection With Compensated Cirrhosis




for

Oral Steroids for Acute Sciatica Due to Herniated Lumbar Disk

Interview with Harley Goldberg, DO, author of Oral Steroids for Acute Radiculopathy Due to a Herniated Lumbar Disk: A Randomized Clinical Trial




for

Outcomes for ACOs vs Traditional Medicare Fee for Service

Interview with Patrick H. Conway, MD, MSc, author of Association of Pioneer Accountable Care Organizations vs Traditional Medicare Fee for Service With Spending, Utilization, and Patient Experience




for

Why the Americans With Disabilities Act Matters for Genetics

Interview with Ellen Wright Clayton, MD, JD , author of Why the Americans With Disabilities Act Matters for Genetics




for

Antibiotics vs Appendectomy for Uncomplicated Appendicitis Treatment

JAMA Topic Review: Edward Livingston, MD, FACS, AGAF, Deputy Editor of JAMA, explores how the study by Paulina Salminen, MD, PhD, supports treating appendicitis without surgery




for

Medical Marijuana for Treatment of Chronic Pain and Other Problems

Interview with Kevin P. Hill, MD, MHS, author of Medical Marijuana for Treatment of Chronic Pain and Other Medical and Psychiatric Problems: A Clinical Review, and Deepak Cyril D'Souza, MBBS, MD, author of Medical Marijuana: Is the Cart Before the Horse?




for

Mortality, Hospitalizations, and Expenditures for the Medicare Population

Interview with Harlan M. Krumholz, MD, SM, author of Mortality, Hospitalizations, and Expenditures for the Medicare Population Aged 65 Years or Older, 1999-2013




for

Mindfulness-Based Stress Reduction for PTSD Among Veterans

Interview with Melissa A. Polusny, PhD, author of Mindfulness-Based Stress Reduction for Posttraumatic Stress Disorder Among Veterans: A Randomized Clinical Trial




for

Referrals From Dialysis Facilities for Kidney Transplantation

Interview with Rachel E. Patzer, PhD, MPH, author of Variation in Dialysis Facility Referral for Kidney Transplantation Among Patients With End-Stage Renal Disease in Georgia. This population epidemiology study uses United States Renal Data System data to characterize dialysis facility–level referral for kidney transplant evaluation in Georgia, the US state with the lowest transplantation rates, and patient and facility factors associated with referral and waitlisting.








for

For Patients: Prostate Cancer Screening

Edward H. Livingston, MD, Deputy Editor of Clinical Reviews and Education and Jon Tilburt, MD, from the Mayo Clinic explain prostate cancer screening. For more information, read the JAMA Patient Page on this topic.




for

Metformin for Adolescents With Type 1 Diabetes

Interview with Ingrid M. Libman, MD, PhD, author of Effect of Metformin Added to Insulin on Glycemic Control Among Overweight/Obese Adolescents With Type 1 Diabetes







for

Antibiotic Therapy for Community-Acquired Pneumonia in Adults

Community acquired pneumonia accounts for 600,000 hospital admissions a year. Many patients with this disease are quite ill and have a very high mortality. To save lives, the appropriate antibiotics should be given in a timely basis, but it is not clear what the best antibiotics are and how long they should be given. In this podcast we interview the author of a JAMA review on community acquired pneumonia, Dr Jonathan Lee, author of Antibiotic Therapy for Adults Hospitalized With Community-Acquired Pneumonia, who performed a systematic review of the literature to determine the best way to treat community acquired pneumonia.