ut The Flutist By www.thecollectionshop.com Published On :: 6/1/2005 The Flutist by John Holyfield is a(n) Limited Edition. The Edition is Limited to Limited Edition to 1500 pcs Full Article
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ut Beauty and the Beast LIMITED EDITION CANVAS By www.thecollectionshop.com Published On :: 7/16/2010 Beauty and the Beast LIMITED EDITION CANVAS by Scott Gustafson is a(n) Limited Edition. The Edition is Limited to Limited Edition of 75 pcs Full Article
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ut aarch64-linux-gnu-binutils 2.38-1 armv7h By parabolagnulinux.org Published On :: Fri, 15 Jul 2022 09:04:36 +0000 A set of programs to assemble and manipulate binary and object files for the aarch64 target Full Article Libre-Testing armv7h
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ut Canadian Blood Services discovery research lab contributes to new knowledge on neutrophils By www.blood.ca Published On :: Thu, 29 Aug 2024 14:37:37 +0000 Canadian Blood Services discovery research lab contributes to new knowledge on neutrophils Plasma Transfusion Blood Thursday, August 29, 2024 Abby Wolfe Dr. Donald R. Branch’s work as a discovery scientist at Canadian Blood Services focuses on immunotherapy, seeking to further enhance understanding of the cellular and molecular mechanisms involved in autoimmune diseases. Based in Toronto, Dr. Branch’s laboratory develops models of rheumatoid arthritis, Alzheimer’s disease, immune thrombocytopenia (ITP) and multiple sclerosis in mice. These models are particularly useful in examining how cells affected by these conditions respond to current therapeutic agents like intravenous immunoglobulin – a blood product made from human plasma commonly known as IVIg – and investigating potential alternative therapeutics. Over the years, Dr. Branch’s lab research findings have included the discovery of a special reagent that makes identification of antibodies easier by “zapping" autoantibodies, answers around unexpected side effects of IVIg therapy, and insights around recipients’ responses to bone marrow transplantation. It has also earned him numerous awards and accolades, including four from AABB, the Association for the Advancement of Blood & Biotherapies. Dr. Don Branch, Canadian Blood Services senior scientist New knowledge about neutrophils Recently, contributions from Dr. Branch’s lab helped a U.K.-based team of researchers discover new information about how neutrophil function and activity is regulated. Neutrophils are a type of white blood cell that are part of the body’s normal immune response. A person’s neutrophil levels may be affected by infections as well as chronic or acute illnesses. Patients who have very low neutrophil counts and/or persistent infections may receive a boost to their neutrophil levels via granulocyte transfusion therapy. However, in some diseases, overactivation of neutrophils can also create an inflammatory environment and harm healthy tissue. The research has been published in the high-impact scientific journal, Nature. This publication has filled a gap in knowledge about the mechanisms involved in maintaining balance between neutrophils’ infection-fighting power and inflammation-causing potential. As Dr. Branch describes: “This research by Dr. Brown and team shows that the myeloid inhibitory C-type lectin enzyme, which is known as MICL, controls neutrophil activity in rheumatoid arthritis. It is likely that MICL also regulates neutrophil activity in general. This suggests that if therapeutics can be designed to target MICL, they may be useful in controlling inflammation and infection. It is a fundamental finding that will change our understanding of the biology of neutrophils.” Discovery research, like the study to which Don and Ruqayyah contributed, is essential to improving patient care in the long run. New biomedical insights are essential to crafting new drugs and new therapeutic approaches in a rational way. Dr. William (Bill) Sheffield, Canadian Blood Services senior scientist and associate director of research Discovery research expertise leads to new collaboration The special mouse model that Dr. Branch’s lab uses is known as K/BxN. In this model, two mouse populations are selectively bred to produce offspring whose genetic material carry an antibody that destroys bone cartilage. An arthritis-causing serum containing this destructive antibody can then be obtained from the mice for use as a reagent in research. This process is termed “serum-transfer arthritis” and has been used by many investigators in the study of treatments that may alleviate the condition. Knowledge of Dr. Branch’s lab’s expertise in this area prompted a connection to the team of researchers at the Universities of Exeter and Aberdeen in the U.K. for this study. Says Dr. Branch, “In 2021, I supported a successful application to Canadian Blood Services’ Blood Efficiency Accelerator Program (BEAP) by Dr. Maria Fernandes, a researcher from Héma-Québec who works with neutrophils. Through this collaboration, Dr. Fernandes was aware that I work on rheumatoid arthritis with K/BxN mice, and she also knew that Dr. Gordon Brown in the U.K. was looking to collaborate with a researcher in this area for some planned neutrophil research. My lab, which included postdoctoral fellow Dr. Ruqayyah Almizraq at the time, contributed to Dr. Brown’s research by providing the sera from our K/BxN mice. With this sera, Dr. Brown and his collaborators were able to induce rheumatoid arthritis and show that it could be resolved by removing the inhibition of a specific enzyme.” Science that is never boring The Branch lab is currently using these same mouse models to investigate whether a recombinant protein called IgG1 Fc hexamer could be an effective replacement for IVIg in the treatment of autoimmune conditions like rheumatoid arthritis and ITP. While early results are promising, continued work is needed. In fact, back in 2018, Dr. Branch was asked in a previous R.E.D. blog post to describe what he found to be the most exciting part of science. Reflecting on the same question now, he reiterates that his response still rings true after 50 years in the field: The most exciting part of science is that when you do good science, you get more questions than you get answers, which means it is never boring. There is no end to imagination; new ideas, theories, experiments and discoveries occur often and provide a level of excitement to which many other professions cannot attest. Dr. Donald (Don) Branch, Canadian Blood Services senior scientist Canadian Blood Services – Driving world-class innovation Through discovery, development and applied research, Canadian Blood Services drives world-class innovation in blood transfusion, cellular therapy and transplantation—bringing clarity and insight to an increasingly complex healthcare future. Our dedicated research team and extended network of partners engage in exploratory and applied research to create new knowledge, inform and enhance best practices, contribute to the development of new services and technologies, and build capacity through training and collaboration. Find out more about our research impact. The opinions reflected in this post are those of the author and do not necessarily reflect the opinions of Canadian Blood Services nor do they reflect the views of Health Canada or any other funding agency. Related blog posts Senior scientist wins prestigious award for discovering a ‘gold standard’ reagent used in transfusion medicine Tuesday, March 28, 2023 Aldis Brennan Dr. Donald Branch, Canadian Blood Services senior scientist, has received the Dale A. Smith Memorial Award for his discovery of the ZZAP reagent. This award, from the Association for the Advancement of Blood & Biotherapies (AABB), recognizes the application of technology to the practice of transfusion medicine or biotherapies. Transfusion Blood Read full story, Senior scientist wins prestigious award for discovering a ‘gold standard’ reagent used in transfusion medicine Interactive lab tour helps undergraduate students learn from Canadian Blood Services senior scientist and team Thursday, March 16, 2023 Beth Binnington, Senior Research Assistant Students from the Undergraduate Pathology Alliance at Western University posed insightful questions to researchers during an interactive visit to the research laboratory of Dr. Donald Branch, Canadian Blood Services senior scientist in February 2023. Plasma Transfusion Blood Read full story, Interactive lab tour helps undergraduate students learn from Canadian Blood Services senior scientist and team Meet the researcher: Dr. Donald Branch Wednesday, February 28, 2018 Dr. Kendra Hodgkinson For this instalment of “Meet the researcher”, we met with Dr. Donald Branch, a scientist at Canadian Blood Services who studies infectious diseases and immunology. How long have you been with Canadian Blood Services? I started with the Canadian Red Cross at the Edmonton Blood Centre in December 1985... Plasma Transfusion Blood Read full story, Meet the researcher: Dr. Donald Branch Full Article
ut How Ancient and Modern Predators Cope with Worn-Out Teeth By scienceblog.com Published On :: Mon, 11 Nov 2024 15:02:42 +0000 Full Article Life & Non-humans
ut Computer Models Reveal Solar Polar Vortices for First Time By scienceblog.com Published On :: Mon, 11 Nov 2024 21:22:27 +0000 Full Article Space
ut Tiny but Mighty: New Printhead Could Speed Up 3D-Printed Organ Development By scienceblog.com Published On :: Tue, 12 Nov 2024 14:35:35 +0000 Full Article Health Technology
ut Air Pollution During Pregnancy and Early Childhood Linked to Increased Autism Risk By scienceblog.com Published On :: Tue, 12 Nov 2024 14:42:28 +0000 Full Article Brain & Behavior Earth Energy & Environment
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ut Scientists Design First Practical Light-Amplifying Crystal That Could Revolutionize Medical Sensors By scienceblog.com Published On :: Tue, 12 Nov 2024 17:50:14 +0000 Full Article Physics & Mathematics Technology
ut Utilizing MapleSim to Improve Assisted Living Devices By www.maplesoft.com Published On :: Tue, 15 Nov 2016 05:00:00 Z A research team from York University have been working on developing more practical and streamlined devices to assist humans with everyday movements, such as standing and sitting. The objective was to determine if energy could be regenerated in prosthetic devices during these movements, similar to the way in which hybrid electric vehicles recover waste heat from braking and convert it into useable energy. Full Article
ut Resolución y construcción de polígonos hiperbólicos convexos y autointersectantes By www.maplesoft.com Published On :: Sat, 25 Sep 2021 04:00:00 Z The worksheet shows a procedure for the resolution and construction of convex and self-intersecting hyperbolic polygons, given 2p-3 data of the sides and angles of the polygon. Full Article
ut State Department Approves $4.9 Billion Sale of E-7 Aircraft To South Korea By www.defensedaily.com Published On :: Tue, 05 Nov 2024 21:24:05 +0000 The State Department approved a potential Foreign Military Sale of $4.92 billion in Boeing [BA] E-7 Wedgetail Airborne Early Warning and Control Aircraft to South Korea. The Defense Security Cooperation […] Full Article International highlights international South Korea
ut Commerce Dept. Seeks Input on Changes to Space Export Controls By www.defensedaily.com Published On :: Wed, 06 Nov 2024 21:40:18 +0000 The U.S. government recently released four rulemakings on space export control designed to strengthen private sector space activity and improve international collaboration. The Department of Commerce and Department of State released four space export control […] Full Article Space highlights
ut Saab Pitches Autonomous Control System For Naval Vessels By www.defensedaily.com Published On :: Wed, 06 Nov 2024 21:41:00 +0000 Sweden’s Saab pitched a new autonomous control system to be used for naval vessels during the Euronaval expo in Paris this month. The company said this new system, Autonomous Ocean […] Full Article International Unmanned Systems autonomy international unmanned systems
ut US Launched Minuteman III ICBM With Three Test Warheads By www.defensedaily.com Published On :: Thu, 07 Nov 2024 17:26:59 +0000 The U.S. Space Force tested the intercontinental ballistic missile’s ability to strike targets with multiple warheads in a Minuteman III launch Tuesday at Vandenberg Space Force Base, Calif. According to […] Full Article Nuclear Modernization
ut Autonomous KC-135 Flight Testing May Begin Next Year By www.defensedaily.com Published On :: Tue, 12 Nov 2024 21:10:32 +0000 Flight testing of an autonomous KC-135 Stratotanker may begin next year. Boston’s Merlin Labs, Inc. and the U.S. Air Force’s 6th Air Refueling Wing at MacDill AFB, Fla., have been testing […] Full Article Advanced / Transformational Technology Air Force Business/Financial Unmanned Systems
ut Jan 25 - SUTLF 2025: Collaborative and Cooperative Learning By www.eltcalendar.com Published On :: Mon, 04 Nov 2024 12:56:59 GMT NanKyu JALT (NanKyu Chapter of the Japan Association for Language Teaching). January 25 (Sat), 9:00-18:00 in Kumamoto. Edward Rubesch. Full Article
ut SUTLF 2025: Collaborative and Cooperative Learning By www.nankyujalt.org Published On :: Sun, 13 Oct 2024 05:30:58 GMT NanKyu JALT (NanKyu Chapter of the Japan Association for Language Teaching). January 25 (Sat) 2025, at SILC Building, Sojo University, Kumamoto. Full Article
ut HN10 - The Mouth and Oropharynx By www.instantanatomy.net Published On :: Mon, 29 Aug 2022 00:11:15 +0000 The tenth in our series on the head and neck describes the Mouth and Oropharynx. See our website for accompanying diagrams Full Article
ut Kastalon Rolls Out New Website By www.achrnews.com Published On :: Mon, 24 Apr 2017 07:30:00 -0400 Kastalon announced the rollout of its new website at www.kastalon.com. The new site offers a look at the company’s extensive lines of standard products, including rollers, pads, bumpers, and sleeves for various uses in materials handling, metals producing and processing, as well as other market applications. Full Article
ut Regal Debuts Progressive New Website By www.achrnews.com Published On :: Tue, 18 Jul 2017 07:30:00 -0400 Regal Beloit Corp. announced it has launched a new, responsive website platform with significant upgrades, additional product features, and a focus on industry solutions. The company’s approach to convert each of its brand-specific domains to the new company-wide platform will occur in phases, starting with the Marathon® Motors North American site. Full Article
ut Regal Debuts Progressive New Website for Marathon Motors By www.achrnews.com Published On :: Wed, 16 Aug 2017 07:30:00 -0400 Regal Beloit Corp. announced it has launched a new Marathon® Motors website for the North American region. The new website contains significant upgrades and additional product features as part of the company’s phased approach to convert all brand-specific domains to the new company-wide platform. Full Article
ut How to Future-Proof HVAC Systems to Meet Efficiency and Carbon Emission Goals By www.achrnews.com Published On :: Fri, 01 Oct 2021 07:00:00 -0400 The major drivers of future-proofed HVAC systems are efficiency, resiliency, electrification, and grid-interactivity. Full Article
ut Department of Energy Seeks to Cut Cost of Enhanced Geothermal Systems By www.achrnews.com Published On :: Wed, 07 Dec 2022 11:00:00 -0500 The DOE aims to build upon current Enhanced Geothermal Shots by accelerating research, development, and demonstrations within enhanced geothermal systems, to tap into and better understand resources while significantly reducing the cost of EGS. Full Article
ut Decarbonization and the Future of HVAC By www.achrnews.com Published On :: Sat, 25 Feb 2023 07:00:00 -0500 At the AHR Expo in Atlanta, Georgia, a panel of experts explored the current state of decarbonization in America, as well as discussed the challenges, opportunities, and solutions that lie ahead. Full Article
ut Misconceptions about Sustainability-Based HVAC Work May Be Hindering Your Ability to Grow By www.achrnews.com Published On :: Fri, 14 Jun 2024 07:00:00 -0400 While implementing new technology may seem like a daunting task, seasoned technicians could find it’s not all that different than the work they are already doing. Full Article
ut Automation Components Inc.: Low Differential Pressure Transmitter By www.achrnews.com Published On :: Wed, 01 Apr 2015 10:00:00 -0400 ACI’s compact sized, A/MLP Series Pressure Transmitter is designed specifically for panel mount, duct and OEM installations. Pressure ranges from +/- 0.5 inch to +/- 20 inches of water column. Full Article
ut Global Plasma Solutions: Air Purification System By www.achrnews.com Published On :: Mon, 27 Jun 2016 07:00:00 -0400 The GPS-iClean is the world’s first self-cleaning, no-maintenance air purification system that can reduce particles, control odors, kill pathogens, and even save energy by reducing ventilation air requirements. Full Article
ut Rapid Growth Puts Contractor on Inc. 5000 List By www.achrnews.com Published On :: Wed, 12 Sep 2018 09:00:00 -0400 Ken Goodrich, CEO of Goettl Air Conditioning, acquired the company in 2013 and has since rapidly expanded its operations to include Tucson, Arizona; Phoenix; Las Vegas; and Southern California. This rapid expansion has been a primary factor in why the company has grown its employee count from less than 100 to more than 417 and increased revenues by five-fold. Full Article
