Team Homan's decision to part ways with Lisa Weagle dramatically changed the look of one of the country's top rinks and put the all-star lead at the top of curling's free agent list.

The men's curling world championship in Glasgow was cancelled Saturday morning to prevent the spread of COVID-19. Brad Gushue and his rink from Newfoundland and Labrador was going to represent Canada after winning the Brier.

The University of Alberta Pandas defeated the UNB Reds 10-2 in the U Sports women's curling final, while the Laurier Golden Hawks topped the Dalhousie Tigers 8-5 for the men's curling title in Portage la Prairie, Manitoba on Sunday.

The Kevin Koe curling team has split with second Colton Flasch after being eliminated from the recent men's national championship in Kingston, Ont., in a tiebreaker game. Flasch joined the foursome in 2018.

The bonspiel took place in Edmonton March 11-14, starting the same day COVID-19 was declared a global pandemic.

The World Curling Federation announced Thursday it is proposing to the International Olympic Committee that the 2021 world curling championships will determine which countries will book their tickets to Beijing 2022.

The time was right for Lisa Weagle to join forces with Olympic champion Jennifer Jones. Jones told CBC Sports' Anastasia Bucsis that the latest addition to her five-person rink "was like the clouds parted and the sun came out."

Will he, given his obsession with the economy?

Just in time for Easter, the story of a blind state leader who is giving up his office to join the Jesuits.

Join our Facebook live on Thursday at noon with Dr. Roselyn Wilson a psychiatrist at St. Joseph’s Healthcare Hamilton’s Youth Wellness Centre. She'll talk with us about how COVID-19 is heightening anxiety in some young people. We'll talk about how to help the young people in your life through the pandemic.

Flattening the curve has been so successful and two areas around Hamilton — Brant and Haldimand-Norfolk — haven't had a new case of COVID-19 in three days, and Burlington has only had two.

The province says no one has to tell others if they get COVID-19. The same goes for businesses or landlords, should employees or tenants get sick. But should you tell?

Front-line nurses from the West 5th campus use a special van to meet patients with mental health problems — primarily those living with schizophrenia— and treat them by doing their blood work.

Fears that COVID-19 would spread at the Hamilton-Wentworth Detention Centre appear not to have materialized — at least not yet.

Two additional men have been charged with first-degree murder in the death of a 17-year-old Brampton boy shot and killed on New Year's Eve.

Curbside pickups offer a bit of hope after months of being shuttered by COVID-19, but while retailers are happy to start getting back to business some are raising questions of fairness and access to opportunity.

The COVID-19 pandemic may be keeping families physically distant, but that doesn't mean you can't show someone you care.

Flurries or rain showers are in the forecast for Hamilton on Friday, Environment Canada says.

A search warrant executed by Hamilton police vice and drugs officers at an address in the city’s east end has resulted in the arrest of a couple and multiple charges, police said in a Friday release.

Hamilton Conservation Authority is re-opening the Hamilton-to-Branford Rail Trail, while the city announced the reopening of the Hamilton Waterfront Trail, between Confederation Park and the Burlington Lift Bridge.

Normal life is slowly resuming as the city of Hamilton begins to relax tight measures set in place because of COVID-19. Mayor Fred Eisenberger said now it's up to the public to help the city move in the right direction by continuing to stay two metres apart from each other and be cautious.

The general field of quantitative biology has advanced significantly on the back of recent improvements in both sequencing technology and proteomics methods. The development of high-throughput, short-read sequencing has revolutionized RNA-based expression studies, while improvements in proteomics methods have enabled quantitative studies to attain better resolution. Here we introduce methods to undertake global analyses of gene expression through RNA and protein quantification in Xenopus embryos and tissues.

Quantifying RNA is an important and necessary step before most RNA analysis techniques. Methods for quantifying RNA can be classified into two categories: ultraviolet (UV) spectrophotometric methods, which are based on the absorption spectra of the purine and pyrimidine bases; and fluorescent dye-based methods, which measure the fluorescence intensity of dyes that selectively fluoresce when bound to nucleic acids. If the RNA sample is pure (i.e., without significant amounts of contaminants such as proteins, phenol, agarose, or other nucleic acids), UV spectrophotometric measurement of the amount of UV irradiation absorbed by the bases is simple and accurate. However, if the sample contains significant quantities of impurities or if the concentration of RNA is very low, it is better to use fluorescent dye-based methods. An overview of spectrophotometric and fluorescent dye-based RNA quantification methods is given here, as are several options for storing purified RNA preparations. Proper storage of RNA samples is important; it can help minimize RNase contamination and consequent sample degradation.

The Xenopus oocyte is a unique model system, allowing both the study of complex biological processes within a cellular context through expression of exogenous mRNAs and proteins, and the study of the cell, molecular, and developmental biology of the oocyte itself. During oogenesis, Xenopus oocytes grow dramatically in size, with a mature oocyte having a diameter of ~1.3 mm, and become highly polarized, localizing many mRNAs and proteins. Thus, the mature oocyte is a repository of maternal mRNAs and proteins that will direct early embryogenesis prior to zygotic genome transcription. Importantly, the Xenopus oocyte also has the capacity to translate exogenous microinjected RNAs, which has enabled breakthroughs in a wide range of areas including cell biology, developmental biology, molecular biology, and physiology. This introduction outlines how Xenopus oocytes can be used to study a variety of important biological questions.

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