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COVID-19 the focus, but Pfizer isn't ignoring other vaccine R&D as its pens new deal

Pfizer and partner BioNTech are right in the middle of one of the most important vaccine trials in the world right now, but that doesn’t mean the Big Pharma is taking its eyes off the inoculation ball elsewhere.




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BioMarin pens gene therapy pact with little-known Swiss biotech

BioMarin Pharmaceutical is boosting its early-stage pipeline by penning a deal with Swiss startup Dinaqor.




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Oberland Capital nabs $1.05B raise for late-stage plays, handing out cash for royalties

Come on in, the water’s warm. After billions already raised by VC firms since the advent of the pandemic for life science companies, Oberland Capital has tossed more than $1 billion into the pot.




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COVID-19: Lilly ramps up to beat the virus with neutralizing antibodies as scientists raise worries

Eli Lilly has teamed with China’s Junshi Biosciences in the U.S., marking the company's second COVID-19 pact to develop neutralizing antibodies against the virus. It promises to be a faster approach than designing a new small-molecule drug would be, but getting from idea to an effective product may not be so simple.




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FDA delays decision on approval of Bristol Myers' CAR-T

The FDA has delayed its decision on whether to approve Bristol Myers Squibb’s CAR-T cell therapy by three months. Bristol Myers attributed the delay to its submission of additional information upon the request of the FDA.




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GSK taps experimental arthritis antibody to calm the cytokine storm hitting COVID-19 patients

GlaxoSmithKline is hard at work with partner Sanofi in getting a vaccine tested for COVID-19, but this morning it said it was now also entering the race to treat patients already hit with the disease.




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Essential oils marketers added to list of coronavirus claims offenders

Some producers of essential oils have thrown their hats into the coronavirus claims ring, according to recent warning letters from the US Food and Drug Administration and the Federal Trade Commission.




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No difference found in caffeine's effects on exercise power among 'fast' or 'slow' metabolizers

A recent study looking at the effects of caffeine on brief, high intensity exercise found the substance improved performance, regardless of genetic variations in how subjects metabolized caffeine.




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UNPA’s Israelsen: ‘We’ve had a good six weeks, but consumers have used some of their last spending power to buy supplements’

While dietary supplement sales have surged in recent months, the extent of the economic damage caused by the novel coronavirus and COVID-19 could lead to some very tough quarters as families and businesses start to run out of money.




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CRN’s Mister: ‘This could be a sea change for the industry as consumers take more interest in their health’

Consumers are turning to dietary supplements in record numbers, but the industry must deliver on the results the products are promising if the industry is to convert them to long term customers, says Steve Mister.




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Bifido probiotic may enhance effects of exercise and boost training results: Study

Combining exercise with a bacterial strain isolated from an Olympic weightlifting gold medalist may synergistically increase endurance compared to training or the probiotic alone, suggests data from a mouse study.




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Supporting Biotech Development in Madison

As part of our follow up to our recent Biotech in Wisconsin Meetup about professional development skills, we are asking folks to fill out this poll.




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We All Need a Risk Framework

I recently read “The Most Important Thing Illuminated: Uncommon Sense for the Thoughtful Investor” by Howard Marks, Chairman and cofounder of Oaktree Capital Management. While I’m not an investor, Juan Serrate (@JPZaragoza1) brought the book to my attention during a Twittersation about risk. In my job developing a discovery into an actual drug, I think

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What is the optimal biotech burn rate?

Ethan Perlstein, founder of Perlstein Lab, asked a question on Twitter and got some great answers from David Grainger, partner at Index Ventures and Katrine Bosley, CEO of Editas Medicine. (You can read the whole thread by clicking through.) @LifeSciVC @sciencescanner @ksbosley @scientre what's the burn rate distribution of biotech NewCos in for the first year of

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Precision in Oncology: Using the Macro and Micro

Last week, the New York Times had a nice piece “A Faster Way to Try Many Drugs on Many Cancers” on basket clinical trials, which matches patients to a therapy based on the genetics of their tumor as opposed to the site of their primary tumor. This type of trial feeds into the current excitement about precision

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Blood: Underappreciated Resource in the Health/Disease?

Alternative title: Pitching a VC on Disruption of Blood Testing You may have seen some recent editorials about the necessary frequency of blood tests for healthy individuals, many of them prompted by a series of tweets from Mark Cuban: Although there are certainly potential dangers in expecting any and all test results to be immediately

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Haitian Doctor Says This Is The Worst Epidemic He's Faced

A major health agency fears a humanitarian crisis. Migrant workers are returning home from the hard-hit Dominican Republic. Medical equipment is in short supply. And social distancing is improbable.




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Anti-Vaccination Activists Join Stay-At-Home Order Protesters

Among those rallying against state shutdown orders are anti-vaccination activists. They see these protests as a way to form political alliances that promote their movement.




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Tracking The Pandemic: How Quickly Is The Coronavirus Spreading State By State?

View our map and graphics to see where COVID-19 is hitting hardest in the U.S., which state outbreaks are growing the fastest and which are leveling off.




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Day Three Notes – JP Morgan Healthcare Conference, San Francisco

Yesterday’s conference sessions surfaced interesting questions and approaches regarding the post-acute sector, bundled payment, emergency medicine and anesthesia. Post-Acute Focus: With more and more focus on the need to rationalize and re-organize the post-acute sector, we have seen multiple industry leaders start to evolve their strategies.  I blogged yesterday about AccentCare’s interesting strategy in the...… Continue Reading




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Brexit is a fact – now deal with it

Following the European Parliament’s vote, the Council has now also agreed to the Brexit with its decision on the conclusion of the withdrawal agreement on behalf of the EU. The EU Parliamentarians sang off the UK members and celebrated that they never have to speak to Nigel Farage again. UK EU civil servants are clearing […]




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Commission working on proposal to postpone MDR date of application for one year

After a statement on a press conference today by Stefan De keersmaecker that had many people very excited quickly, the official announcement came later in the afternoon: Here is what I think about this development. Work on a proposal ongoing The Commission announced that ‘work on a proposal to postpone the date of application’. This tells […]




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Andy Serkis (and maybe Gollum?) will read 'The Hobbit' for coronavirus charities

Andy Serkis, who plays Gollum in the "Lord of the Rings" films, announced that he will livestream a reading of J.R.R. Tolkien's "The Hobbit" on Friday.




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U.N. nearly triples its coronavirus fundraising goal to $6.7 billion

The U.N. triples its fundraising target for fighting the coronavirus, even as President Trump plans to freeze U.S. aid to its principal health agency.




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Editorial: L.A.'s trails and parks are reopening. C'mon, people, don't screw it up this time

For goodness sake, if you're going to hike, wear a mask.




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San Francisco will allow certain businesses to reopen beginning May 18

San Francisco will allow certain businesses to reopen beginning May 18 as it eases its stay-at-home orders. But officials warn that they will keep track to make coronavirus infections don't spike.




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Judge grants request to delay start of prison sentence for former Rep. Duncan Hunter

A federal judge found that the uncertainty surrounding the COVID-19 pandemic was good cause for the delay.




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Letters to the Editor: Old Americans shouldn't have to prove their value to combat ageism

The idea that old people are worth something because they contribute significantly to society puts us on a slippery slope.




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Column: No, wearing a mask isn't for libs. It's for people who don't want to die

The daft showdown over coronavirus masks wouldn't matter if we didn't live in the political tinderbox that is Trump's America.




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How to get legally married during the coronavirus crisis

Marriage, like many aspects of life, has changed. Here's what you need to know about getting a license and the rest of a process that was already complicated.




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An Orange County cafe opened in defiance of Newsom. Now it's the center of stay-at-home resistance

When it opened last week for the first time since mid-March, Nomads Canteen in San Clemente quickly filled with customers eager to get out of the house and return to some sense of normalcy amid the COVID-19 pandemic.




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Column: The cruise ship industry is sinking. I'm OK with that

Norwegian Cruise Line says it's in danger of going out of business. Maybe that's not the worst thing for an industry of floating petri dishes.




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At protests, mostly white crowds show how pandemic has widened racial and political divisions

Coronavirus pandemic widens racial and political divisions




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Mystery syndrome similar to Kawasaki disease linked to coronavirus at Children's Hospital Los Angeles

Doctors have recently identified a condition called pediatric inflammatory multi-system syndrome among children who have tested positive for antibodies against COVID-19.




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Season Interrupted: Middlebury-bound Riley Griffis can hang in the deep end

Loyola swimming star Riley Griffis quickly read the reality of life outside the pool: 'The time away has shown it's something I need to function."




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All 10 family members in this house got COVID-19. Their patriarch didn't survive

The Ramirezes never thought the coronavirus would get them. They took every precaution, but the virus still found its way into their home. Over the course of days, each member of the 10-person household became infected. Three were hospitalized. And one, the family patriarch, died.




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Coronavirus testing has come to skid row. But what happens when infected patients disappear?

Even as Mayor Eric Garcetti has extended testing to everyone in L.A. County, doing the same for homeless people has proved to be far more challenging.




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How coronavirus — a 'rich man's disease' — infected the poor

Many countries saw the coronavirus as a "rich man's disease" imported by overseas travelers. It has since hit marginalized groups the hardest.




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Coronavirus is making expectant parents anxious. This doula wants to help

Carson Meyer, daughter of an NBCUniversal executive and sister of jewelry designer Jennifer Meyer, is reaching parents-to-be virtually in the COVID-19 age.




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Pour one out for 2020 grads. It'll be hard to find a job in this market

The coronavirus outbreak makes finding jobs more difficult for everyone. College seniors face unique career challenges.




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L.A. traffic is starting to pick up again, and travel speeds are slowing down

California reopening: Traffic volume is steadily creeping up, and travel times are getting longer.




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What's open and closed this busy weekend: Beaches, parks and trails in Southern California

City and county trails reopen this weekend. Almost every day, the rules change in the beaches and parks of Southern California. Here's the latest.




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Column: America's tolerance for mass murder is the coronavirus' best friend

The America that condones mass murder of children is allowing the coronavirus to spread.




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3 more inmates die at Chino prison as coronavirus infections continue to spread

Three more inmates died of coronavirus and the number who are infected has more than doubled at the California state prison in Chino, officials said.




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Coronavirus death toll rises to 71 in Orange County

In the past week, Orange County has announced 21 deaths linked to COVID-19, pushing the total since the pandemic began to 71.




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'Chinese virus' and other COVID-19 racism have designers, stylists of Asian heritage pushing back

Enough is enough, says a growing number of creatives from the fashion industry, including designer Kimora Lee Simmons, stylist Jeanne Yang and designer Prabal Gurung.




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'It's not what this town is about': Seal Beach's Main Street struggles to come back

It is an "eerie" day in Seal Beach as businesses struggle to come back and crowds stay away.




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News Analysis: Is the coronavirus crisis reason to worry about how other nations view U.S. leadership?

U.S. leadership, or the lack thereof, in the time of coronavirus




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Commissioner Adam Silver tells NBA players that resuming the season remains fluid

Adam Silver told NBA players that a return to the court is up in the air but that games could be held in Las Vegas or Orlando, likely without fans.




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Group calls for social distancing, more testing during coronavirus counter-protest in Huntington Beach

Three members of the group Indivisible OC 48 staged an hourlong protest to bring attention to the people who are following Gov. Gavin Newsom's stay-at-home orders during the COVID-19 pandemic.