What's in a name? Which is it — COVID-19 or coronavirus?…

Ever wonder why there are no Thai fast food places?…

Growing up, Luke Parker played sports.…

The Inlander is a community newspaper covering news, politics, events, happy hour, everything that's happening today, things to do on the weekend, in Spokane, Coeur d'Alene, the greater Inland Northwest and beyond.

[IMAGE-1] Crystal Bertholic has been a leader in the region's craft cocktail revival since the beginning. Before she got her start shaking, stirring and straining mixed drinks, Bertholic was steaming milk and roasting coffee; then pouring craft beers.…

[IMAGE-1] The days of Post Falls being merely an exit you point out to your restless kids to assure them you're almost to Coeur d'Alene are over. In the next 20 years, the little town is projected to explode to 100,000 people.…

[IMAGE-1] Visiting Spokane Valley is a little like when a child visits their grandparents' place: At first you don't understand why you're there, but after you leave with new toys, clothes and a full stomach, you can't wait to go back. And the Spokane Valley Mall has all of that.…

The Showcase celebrity golf tournament attracts big-time athletes and pop stars each year.…

[IMAGE-1] It's not surprising the most popular destinations for Inlander readers in North Spokane involve shopping — NorthTown Mall and the Garland District were the top vote-getters in this year's poll — but looking at the overall results, one quickly realizes the region north of the river has a lot going on. Riverside State Park and the Little Spokane River were popular picks, too, along with Mt. Spokane Ski & Snowboard Park; clearly people love to get outside up north in between their trips to Bon Bon or Buffalo Wild Wings.…

[IMAGE-1] Midtown Coeur d'Alene. The pedestrian-friendly strip of restaurants and shops that runs north-south along Fourth Street in between Garden and Harrison avenues.…

For people who love playing, a day on the worst possible golf course is better than any day not swinging the clubs.…

[IMAGE-1] The people were unequivocal: The South Perry District and Manito Park are the most popular reasons to visit the South Hill, and for good reason. Manito Park is sprawling and beautiful, with 78 acres of native and cultivated landscape and 20 acres of botanical gardens.…

One great thing about seeing "oldies" acts on tour is the vivid reminder you get that groups in the old days really knew how to serve their fans. Take the Commodores, for example, a group with a 52-year-history that swung by Northern Quest Resort & Casino Thursday night.…

Erin Haskell Gourde isn't afraid to mix it up a little.…

Every serious pinball player remembers their first machine.…

Mosey on up to the bar at Lil Sumthin' Saloon for a sip of Southern hospitality by way of Texas, and a samplin' of some old-fashioned country vibes.…

Don't be caught empty-handed (or empty-hearted) this Valentine's Day, coming up Friday, Feb. 14.…

While its main goal is to introduce the humble breakfast taco to more Spokane eaters, owners of the new quick food stop Taco Vado say breakfast burritos have actually been its bestselling menu item since opening about a month ago.…

Tool's music is not only not for everyone, it's such a challenging polyglot of oft-derided musical styles that it risks not being for anyone. And yet, the quartet's blend of prog-rock, art-rock, metal and performance art has become a genre unto itself over the course of 30 years, and it's a genre that has proved remarkably commercial.…

A little more than a year ago, local French-inspired bakery miFlavour moved into a building on East Sprague Avenue after two years in a shared commercial kitchen.…

ProPublica’s health reporter Caroline Chen explains what the conversation around asymptomatic coronavirus carriers is missing, and what we need to understand if we’re going to beat this nefarious virus together. By Caroline Chen, ProPublica In the early days of the coronavirus outbreak in the U.S., around the last week of February, I joked to a colleague that maybe now, finally, people would learn how to wash their hands properly.…

The Cannabis Issue In a normal year, cannabis stores would be cashing in this April.…

By Michael D. Shear and Sarah Mervosh WASHINGTON — President Donald Trump on Friday openly encouraged right-wing protests of social distancing restrictions in states with stay-at-home orders, a day after announcing guidelines for how the nation’s governors should carry out an orderly reopening of their communities on their own timetables.…

New TV ads that started airing on morning shows throughout the Spokane region are aimed at grocery shoppers, but they're not hawking deals on cabbage or Cap'n Crunch.…

At around 5:30 pm on Thursday, there were two camps of people set up in Coeur d'Alene Park in Browne's Addition.…

Yesterday, Spokane Mayor Nadine Woodward and other local leaders urged Gov. Jay Inslee to allow Spokane County to open on a different schedule than the rest of the state.  Inslee, however, wouldn't budge.…

When Washington Gov. Jay Inslee solemnly looked into the camera on Friday, May 1, he wasn't ready to declare victory yet.…

Last week, the New York Times dropped a terrifying story: Asian Giant Hornets, or "murder hornets" as more J. Jonah Jameson-esque researchers like to call them, have been identified in Western Washington. These insects can grow up to 2 inches long, can rip the heads off an entire hive of honeybees in a matter of hours, and have dagger-like stingers that pierce beekeeper suits to deliver a sting that sears like molten acid.…

The present invention relates to a compound of formula A, wherein R is alkyl. Compound A may be used as an intermediate in the preparation of O-desmethyl venlafaxine or a salt thereof, and the present invention provides such a preparation, as well as a process for preparing the compound of formula A.

Novel indansulfamide derivatives or a pharmaceutically acceptable salt thereof such as N-[(1S)-2,2,5,7-tetrafluoro-2,3-dihydro-1H-inden-1-yl]sulfamide, N-[(1S)-2,2,4,7-tetrafluoro-2,3-dihydro-1H-inden-1-yl]sulfamide, (+)-N-(2,2,4,6,7-pentafluoro-2,3-dihydro-1H-inden-1-yl)sulfamide, have an action of improving Seizure Severity Index (Score) in mice kindling model. Thus the compounds or the salt thereof are expected as a drug for treating epilepsy.

A nonmetallic compound having an ionic bond with a halide ion is used as a catalyst for living radical polymerization. Even if a radical initiator is not used, a monomer can be subjected to a radical polymerization to obtain a polymer having narrow molecular weight distribution. The cost of the living radical polymerization can be remarkably reduced, and it is made possible to prevent adverse effects of using a radical initiator (such as side reactions). The present invention is significantly more environmentally friendly and economically excellent than conventional living radical polymerization methods, due to advantages such as low toxicity of the catalyst, low amount of the catalyst necessary, high solubility of the catalyst, mild reaction conditions, and no coloration/no odor, etc. The catalyst can be applied to various monomers and enables synthesis of high molecular weight polymers.

A library of macrocyclic compounds of the formula (I) where part (A) is a bivalent radical, a —(CH2)y— bivalent radical or a covalent bond;where part (B) is a bivalent radical, a —(CH2)z— bivalent radical, or a covalent bond;where part (C) is a bivalent radical, a —(CH2)t— bivalent radical, or a covalent bond; andwhere part (T) is a —Y-L-Z— radical wherein Y is CH2 or CO, Z is NH or O and L is a bivalent radical. These compounds are useful for carrying out screening assays or as intermediates for the synthesis of other compounds of pharmaceutical interest. A process for the preparation of these compounds in a combinatorial manner, is also disclosed.

The invention concerns a new process for the preparation of crystalline form of agomelatine from a solution of agomelatine in a solvent, characterized in that the agomelatine is crystallized by instantaneous precipitation from said solution, at a temperature equal to or below −10° C.

A process for reductive amination of aliphatic cyanoaldehydes to aliphatic diamines comprising (1) providing a mixture of 1,3-cyanocyclohexane carboxaldehyde and/or 1,4-cyanocyclohexane carboxaldehyde; (2) contacting said mixture with a metal carbonate based solid bed or a weak base anion exchange resin bed at a temperature from 15 to 40 ° C. for a period of at least 1 minute; (3) thereby treating said mixture, wherein said treated mixture has a pH in the range of 6 to 9; (4) feeding said treated mixture, hydrogen, and ammonia into a continuous reductive amination reactor system; (6) contacting said treated mixture, hydrogen, and ammonia with each other in the presence of one or more heterogeneous metal based catalyst systems at a temperature from 80 ° C. to 160 ° C. and a pressure from 700 to 3500 psig; (7) thereby producing one or more cycloaliphatic diamines is provided.

A compound represented by Formula 1 below and an organic light-emitting device including an organic layer containing the compound of Formula 1: wherein R1 to R4, X and Y, a and b, and m and n are defined as in the specification.

Provided are an anti-static and anti-microbial surface treatment agent including a quaternary ammonium salt compound as an active ingredient and a method of preventing a polymer fiber from developing static electricity by using the surface treatment agent. The quaternary ammonium salt compound has excellent anti-static and anti-microbial effects for the prevention or improvement of static electricity in a polymer fiber. Accordingly, the quaternary ammonium salt compound is suitable for use as a fabric softener, or an anti-static agent, and also, provides anti-microbial effects to a polymer fiber.

Disclosed is a process for preparing an aryloxyalkylene amine compound via an aminoethylation reaction comprising: a) reacting an aromatic hydroxyl compound in the presence of a basic catalyst with a 2-oxazolidinone compound of the formula II to form an intermediate reaction product; wherein R3 is selected from the group consisting of hydrogen or lower alkyl having 1 to 6 carbon atoms, R4 is selected from the group consisting of hydrogen, straight or branched chain alkyl having from one to six carbon atoms, phenyl, alkaryl, or arylalkyl; and b) reacting the intermediate product of step a) with a polyalkylene polyamine.

A process for conversion of aliphatic bicyclic amines to aliphatic diamines including contacting one or more bicyclic amines selected from the group consisting of 3-azabicyclo[3.3.1]nonane and azabicyclo[3.3.1]non-2-ene with ammonia and hydrogen, and alcohols in the presence of heterogeneous metal based catalyst systems, a metal selected from the group consisting of Co, Ni, Ru, Fe, Cu, Re, Pd, and their oxides at a temperature from 140° C. to 200° C. and a pressure from 1540 to 1735 psig for at least one hour reactor systems; forming a product mixture comprising aliphatic diamine(s), bicyclic amine(s), ammonia, hydrogen, and alcohol(s); removing said product mixture from the reactor system; removing at least some of the ammonia, hydrogen, water, alcohols, bicyclic amines from said product mixture; thereby separating the aliphatic diamines from said product mixture.

Borazine derivatives are used in the manufacture of electronic devices, in particular electroluminescent and semiconductor devices. More specifically, stable borazine derivatives include boron atoms substituted by aryl groups used in one or more layers of an electroluminescent or a semiconductor device, in particular in the emissive layer of organic light-emitting devices (OLED).

Techniques for evaluation and/or retraining of a classification model built using labeled training data. In some aspects, a classification model having a first set of weights is retrained by using unlabeled input to reweight the labeled training data to have a second set of weights, and by retraining the classification model using the labeled training data weighted according to the second set of weights. In some aspects, a classification model is evaluated by building a similarity model that represents similarities between unlabeled input and the labeled training data and using the similarity model to evaluate the labeled training data to identify a subset of the plurality of items of labeled training data that is more similar to the unlabeled input than a remainder of the labeled training data.

A system and method that facilitates urban traffic state detection based on support vector machine (SVM) and multilayer perceptron (MLP) classifiers is provided. Moreover, the SVM and MLP classifiers are fused into a cascaded two-tier classifier that improves the accuracy of the traffic state classification. To further improve the accuracy, the cascaded two-tier classifier (e.g., MLP-SVM), a single SVM classifier and a single MLP classifier are fused to determine a final decision for a traffic state. In addition, fusion strategies are employed during training and implementation phases to compensate for data acquisition and classification errors caused by noise and/or outliers.

A computer-implemented method is provided for statistical data learning under privacy constraints. The method includes: receiving, by a processor, a plurality of pieces of statistical information relating to a statistical object and aggregating, by the processor, the plurality of pieces of statistical information so as to provide an estimation of the statistical object. Each piece of statistical information includes an uncertainty variable, the uncertainty variable being a value determined from a function having a predetermined mean. The number of pieces of statistical information aggregated is proportional to the reliability of the estimation of the statistical object.

A modeling framework for evaluating the impact of weather conditions on farming and harvest operations applies real-time, field-level weather data and forecasts of meteorological and climatological conditions together with user-provided and/or observed feedback of a present state of a harvest-related condition to agronomic models and to generate a plurality of harvest advisory outputs for precision agriculture. A harvest advisory model simulates and predicts the impacts of this weather information and user-provided and/or observed feedback in one or more physical, empirical, or artificial intelligence models of precision agriculture to analyze crops, plants, soils, and resulting agricultural commodities, and provides harvest advisory outputs to a diagnostic support tool for users to enhance farming and harvest decision-making, whether by providing pre-, post-, or in situ-harvest operations and crop analyzes.

A spiking neuron-based working memory device is provided. The spiking neuron-based working memory device includes an input interface configured to convert input spike signals into respective burst signals having predetermined forms, and output a sequence of the burst signals, the burst signals corresponding to the input spike signals in a burst structure, and two or more memory elements (MEs) configured to sequentially store features respectively corresponding to the outputted sequence of the burst signals, each of the MEs continuously outputting spike signals respectively corresponding to the stored features.

Methods, apparatuses and articles of manufacture for use in a mobile device to determine whether a dynamic user profile is to transition from a first state to a second state based, at least in part, on one or more sensed indicators. The dynamic user profile may be indicative of one or more current inferable user behavior contexts for a user co-located with the mobile device. The mobile device may transition a dynamic user profile from a first state to a second state, in response to a determination that the dynamic user profile is to transition from the first state to the second state, and operatively affect one or more functions performed, at least in part, by the mobile device based, at least in part, on the transition of the dynamic user profile to the second state.

A method for performing relational analysis of parsed input is employed to create a visual map of knowledge information. A title, header or subject line for an input item of information is parsed into syntactical components of at least a subject component and any predicate component(s) relationally linked as topic and subtopics. A search of topics and subtopics is carried out for each parsed component. If a match is found, then the parsed component is taken as a chosen topic/subtopic label. If no match is found, then the parsed component is formatted as a new entry in the knowledge map. A translation function for translating topics and subtopics from an original language into one or more target languages is enabled by user request or indicated user preference for display on a generated visual map of knowledge information.

In embodiments of the present invention improved capabilities are described for a computer program product embodied in a computer readable medium that, when executing on one or more computers, helps determine an unknown user's preferences through the use of internet based social interactive graphical representations on a computer facility by performing the steps of (1) ascertaining preferences of a plurality of users who are part of an internet based social interactive construct, wherein the plurality of users become a plurality of known users; (2) determining the internet based social interactive graphical representation for the plurality of known users; and (3) inferring the preferences of an unknown user present in the internet based social interactive graphical representation of the plurality of known users based on the interrelationships between the unknown user and the plurality of known users within the graphical representation.

A method, system and computer program product for generating answers to questions. In one embodiment, the method comprises receiving an input query, decomposing the input query into a plurality of different subqueries, and conducting a search in one or more data sources to identify at least one candidate answer to each of the subqueries. A ranking function is applied to each of the candidate answers to determine a ranking for each of these candidate answers; and for each of the subqueries, one of the candidate answers to the subquery is selected based on this ranking. A logical synthesis component is applied to synthesize a candidate answer for the input query from the selected the candidate answers to the subqueries. In one embodiment, the procedure applied by the logical synthesis component to synthesize the candidate answer for the input query is determined from the input query.

A computer-implemented method for classifying documents for data loss prevention may include 1) identifying training documents for a machine learning classifier configured for data loss prevention, 2) performing a semantic analysis on training documents to identify topics within the set training documents, 3) applying a similarity metric to the topics to identify at least one unrelated topic with a similarity to the other topics within the plurality of topics, as determined by the similarity metric, that falls below a similarity threshold, 4) identifying, based on the semantic analysis, at least one irrelevant training document within the set of training documents in which a predominance of the unrelated topic is above a predominance threshold, and 5) excluding the irrelevant training document from the set of training documents based on the predominance of the unrelated topic within the irrelevant training document. Various other methods, systems, and computer-readable media are also disclosed.

An apparatus for recognizing a representative user behavior includes a unit-data extracting unit configured to extract at least one unit data from sensor data, a feature-information extracting unit configured to extract feature information from each of the at least one unit data, a unit-behavior recognizing unit configured to recognize a respective unit behavior for each of the at least one unit data based on the feature information, and a representative-behavior recognizing unit configured to recognize at least one representative behavior based on the respective unit behavior recognized for each of the at least one unit data.