The Toronto Police Services Board unanimously approved a new five-year hiring plan for the force on Tuesday.

Brampton has reached a tentative deal with nearly 1,200 city workers who have been on strike since last week, according to Mayor Patrick Brown and the union.

Macroeconomic risks for grains and oilseeds include China's growth and FX rates.

The high cost of pet care can be an unfair burden to place on your family when you’re gone. Experts say you should set aside cash pet care expenses, and make sure you have a trusted beneficiary in your will.

At 101-years-old, Chase is one of a dwindling number of living veterans in the city who served in the second world war as a member of the Royal Canadian Air Force. 

Sgt. Harman Dhaliwal, who is from Calgary, says he's proud to be a part of the growing exhibit that highlights the relationship between the Sikh faith and military service.

A new course offered to nursing students at the University of Calgary is shining a light on the impacts of colonization on the health experiences of Indigenous peoples.

Some Ukrainians living in Calgary say they're even more worried for their friends and family back home in light of Donald Trump's election win.

Calgarians who contributed to peacekeeping missions around the world reflected on the country's contributions to this work, highlighting the country's mission in Cyprus, which started 60 years ago.

The provincial government is seeking contractors to restore hundreds of kilometres of land where fireguards were created during the 2023 wildfire season.

The Calgary-based team beat Hamilton Forge FC in a 2-1 nail-biter at home on Saturday, in front of a sold-out crowd of over 7,000 fans at Spruce Meadows.

New rebuilding regulations in Jasper have been approved, but roadblocks — including the sheer number of people that are needed for construction — are popping up.

After Canada Post workers gave a 72-hour notice to strike early Tuesday, some Calgary business owners are worried about what this means for holiday season sales. 

Eyare died of injuries she sustained while moving between back of house spaces, Wilder Institute director of animal care, health and welfare, Colleen Baird said Tuesday.

Charlottetown-born curler Brett Gallant says competing in the Olympics will be a dream come true for him and his fiancée, Jocelyn Peterman, even if COVID-19 protocols will make it difficult for them to see each other.

After COVID-19 challenges forced the cancellation of Canada's mixed doubles trials, several top curlers are anxiously waiting to learn whether they will be chosen to represent the country in the discipline at the Beijing Games.

The cancellation of the mixed doubles curling trials has generated a wide variety of emotions among players — illuminating a handful of issues, particularly about scheduling and the selection process as a whole.

Kamloops, B.C., has been selected as the host city of the 2023 Scotties Tournament of Hearts.

It's not a complete surprise that curling and other sports have been cancelled because of the COVID-19 pandemic, but it doesn't make it any easier on teams that had their hopes of representing Northern Ontario at a national curling level dashed.

The OCA's decision Friday to announce that Rachel Homan's team would only represent the province at the national championship if the skip wasn't picked for the Olympic mixed doubles team generated criticism from some corners and confusion from others.

Laura Walker made a game-winning draw Sunday afternoon to win the Alberta women's curling playdowns and secure a berth in the upcoming national championship.

It’s official — Team Galusha will be representing the N.W.T. at the 2022 Scotties Tournament of Hearts in Thunder Bay later this month.

The oft-discussed wild-card setup at the national championships took centre stage again Monday with the release of updated rankings that appeared to determine the play-in game matchup at the Scotties Tournament of Hearts.

Rachel Homan and John Morris join That Curling Show fresh off the news they have been chosen to represent Canada in mixed doubles curling at the Beijing Olympics.

Curling Canada, with the assistance of Own the Podium and the Canadian Olympic Committee, announced Rachel Homan and John Morris as the mixed doubles team for Canada competing at the Beijing Olympics.

Now that all of Canada's Olympic curling teams are finally set, CBC Sports' daily newsletter takes a look at the three tournaments.

Rachel Homan and John Morris weren't the only ones celebrating after their selection to wear the Maple Leaf in mixed doubles curling competition at the Beijing Olympics. The nomination also cleared the path for Team Hollie Duncan to represent Ontario at the national championship.

As some qualifying events in curling get cancelled, organizers in this region and across the country are starting to have to choose teams based on a ranking system to determine who gets to compete.

Newly announced mixed doubles duo Rachel Homan and John Morris, skips Jennifer Jones and Brad Gushue, and broadcasters Mike Harris, Joanne Courtney and Bruce Rainnie all break down a busy week in curling news.

Canadian curler Kaitlyn Lawes looks back on her Olympic gold in mixed doubles at PyeongChang 2018, reflects on her disappointment in not qualifying with Team Jones in 2018, and her mentality heading into Beijing 2022, looking to add to her two Olympic gold medals.

Curling Canada says the Scotties Tournament of Hearts in Thunder Bay, Ont., will operate under Ontario's current public health measures and an approved framework from the office of the chief medical officer.

CME Group, the world's leading derivatives marketplace, today announced its new CBL Australian Carbon Credit Unit (ACCU) futures have launched and are available for trading. A total of five...

Record revenue of $1.6 billion Record quarterly ADV of 28.3 million contracts - the second consecutive quarter of volume, open interest growth across every asset class CHICAGO, Oct. 23, 2024...

CME Group, the world's leading derivatives marketplace, today announced its new Spodumene CIF China (Fastmarkets) futures have launched and are available for trading. A total of 29 contracts...

CME Group, the world's leading derivatives marketplace, today announced it has received approval from the National Futures Association (NFA) to establish a futures commission merchant (FCM). "We...

CME Group, the world's leading derivatives marketplace, today announced that open interest in its global benchmark Henry Hub futures contract reached a record 1.73 million contracts on October 30,...

Record October ADV for interest rate, energy, metals and agricultural products Record October ADV across U.S. Treasury and SOFR complexes All-time record monthly ADV in U.S. Treasury options and...

Farmer sentiment saw an unexpected surge in October ahead of the upcoming U.S. election, according to the latest Purdue University/CME Group Ag Economy Barometer. The index rose to 115, marking a...

CME Group, the world's leading derivatives marketplace, today declared a fourth-quarter dividend of $1.15 per share. The dividend is payable December 27, 2024, to shareholders of record as of...

Indiana University took first place, with the rest of the top five from outside the United States Record participation from nearly 570 teams across 24 countries CHICAGO, Nov. 7, 2024 /PRNewswire/...

Chief Financial Officer Lynne Fitzpatrick Appointed to President and CFO Chief Operating Officer Julie Holzrichter to Step Down and Assume Advisory Role Suzanne Sprague to Succeed Holzrichter CHICAGO,

Mosquitoes transmit deadly pathogens from person to person as they obtain the blood meal that is essential for their life cycle. Female mosquitoes of many species are unable to reproduce without consuming protein that they obtain from blood. This developmental stage makes them highly efficient disease vectors of deadly pathogens. They can transmit pathogens between members of the same species and different species that can provide a route for evolving zoonotic viruses to jump from animals to humans. One possible way to develop novel strategies to combat pathogen transmission by mosquitoes is to study the sensory systems that drive mosquito reproductive behaviors, in particular the neural architecture and circuits of mosquito sensory afferent neurons, the central circuits that process sensory information, and the downstream circuits that drive reproductive behaviors. The study of mosquito neuroanatomy and circuitry also benefits basic neuroscience, allowing for comparative neuroanatomy in insect species, which has great value in the current model species-heavy landscape of neuroscience. Here, we introduce two important techniques that are used to study neuroanatomy and neural circuitry—namely, immunofluorescent labeling and neural tracing. We describe how to apply these approaches to study mosquito neuroanatomy and describe considerations for researchers using the techniques.

A researcher may have many reasons for wanting to establish new laboratory colonies from field-collected mosquitoes. In particular, the ability to study the diversity found within and among natural populations in a controlled laboratory environment opens up a wide range of possibilities for understanding how and why burdens of vector-borne disease vary over space and time. However, field-collected mosquitoes are often more difficult to work with than established laboratory strains, and considerable logistical challenges are involved in safely transporting field-collected mosquitoes into the laboratory. Here, we provide advice for researchers working with Aedes aegypti, Anopheles gambiae, and Culex pipiens, as well as notes on other closely related species. We provide guidance on each stage of the life cycle and highlight the life stages for which it is easiest to initiate new laboratory colonies for each species. In accompanying protocols, we provide methods detailing Ae. aegypti egg collection and hatching as well as how to transport larvae and pupae from the field.

Sleep is likely a whole-brain phenomenon, with most of the brain probably benefiting from this state of decreased arousal. Recent advances in our understanding of some potential sleep functions, such as metabolite clearance and synaptic homeostasis, make it evident why the whole brain is likely impacted by sleep: All neurons have synapses, and all neurons produce waste metabolites. Sleep experiments in the fly Drosophila melanogaster suggest that diverse sleep functions appear to be conserved across all animals. Studies of brain activity during sleep in humans typically involve multidimensional data sets, such as those acquired by electroencephalograms (EEGs) or functional magnetic resonance imaging (fMRI), and these whole-brain read-outs often reveal important qualities of different sleep stages, such as changes in frequency dynamics or connectivity. Recently, various techniques have been developed that allow for the recording of neural activity simultaneously across multiple regions of the fly brain. These whole-brain-recording approaches will be important for better understanding sleep physiology and function, as they provide a more comprehensive view of neural dynamics during sleep and wake in a relevant model system. Here, we present a brief summary of some of the findings derived from sleep activity recording studies in sleeping Drosophila flies and discuss the value of electrophysiological versus calcium imaging techniques. Although these involve very different preparations, they both highlight the value of multidimensional data for studying sleep in this model system, like the use of both EEG and fMRI in humans.

The establishment of neural connectivity is a major part of neural development. The central nervous system (CNS) midline is the most characterized axon guidance choice point, and work in Drosophila has played a pivotal role in understanding the molecular mechanisms responsible. Axons respond to attractive cues such as Netrin via the Frazzled receptor, and repulsive cues such as Slit via Robo receptors. Both signals are expressed at the CNS midline, affect pioneer axons, and have dramatic effects on the axon scaffold as a whole. Here, we focus on previous research analyzing classic mutants in the Slit/Robo pathway, which can readily be detected with a dissecting microscope. We also discuss analyzing these mutants in a teaching lab situation. The combination of sophisticated genetics and reliable axonal markers in Drosophila allows phenotypic analysis to be performed at the single-cell level. The elaborate architecture of neurons is very sensitive to disruption by genetic mutations, allowing the effects of novel mutations to be easily detected and assessed.

CRISPR–Cas9 has revolutionized gene editing for traditional and nontraditional model organisms alike. This tool has opened the door to new mechanistic studies of basic mosquito biology as well as the development of novel vector control strategies based on CRISPR–Cas9, including gene drives that spread genetic elements in the population. Although the promise of the specificity, flexibility, and ease of deployment CRISPR is real, its implementation still requires empirical optimization for each new species of interest, as well as to each genomic target within a given species. Here, we provide an overview of designing and testing single-guide RNAs for the use of CRISPR-based gene editing tools.

OM Montenegro put on a two week Beach Outreach in the city of Bar.

OM Montenegro holds a programme for local friends to learn and talk about God.

OM Montenegro has discovered that if they are faithful and patient, they can eventually walk through doors that had once seemed closed.