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Clinicians and autistic transgender youth partner to create first community-built care model

The first ever set of specific recommendations to support transgender autistic young people was co-created by these youth and their families working hand-in-hand with clinical experts. The resulting model offers clinicians a set of concrete ways to provide this unique population the support they need.




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Molecule reduces multiple pathologies associated with Alzheimer's disease

When tested in brain cells and in a mouse model of Alzheimer's disease, a new compound significantly reduced the number of amyloid plaques in the brain, lessened brain inflammation and diminished other molecular markers of the disease.




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The great unconformity

The geologic record is exactly that: a record. The strata of rock tell scientists about past environments, much like pages in an encyclopedia. Except this reference book has more pages missing than it has remaining. So geologists are tasked not only with understanding what is there, but also with figuring out what's not, and where it went.




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The Lancet Rheumatology: Small observational study of patients with severe COVID-19 treated with the arthritis drug anakinra finds clinical improvements

The first study to report use of the rheumatoid arthritis drug anakinra to treat COVID-19 patients found that high-dose anakinra was safe and was associated with respiratory improvements and reduced signs of cytokine storm [1] in 72% (21/29) of patients, according to results from patients studied for 21 days (enrolled from 17 to 27 March 2020) in a Milan hospital, published in The Lancet Rheumatology journal.




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Treatment for Diverticulitis -- updated ASCRS Guidelines published in Diseases of the Colon & Rectum

Reflecting research-driven changes in clinical practice, a revised set of evidence-based recommendations for the medical and surgical treatment of left-sided colonic diverticulitis has been published in Diseases of the Colon & Rectum (DC&R), the official journal of the American Society of Colon and Rectal Surgeons (ASCRS). The journal is published by Wolters Kluwer.




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Using digital twins to design more sustainable cities

Over the past several years, a collaboration at HLRS has been developing a digital twin of Herrenberg, a small city just outside of Stuttgart, Germany. The Herrenberg study has already provided valuable information for city planners and government officials in the state of Baden-Württemberg, and paves the way for improving the model to include additional kinds of data.




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Do I look mad? Reading facial cues with the touch-screen generation

Are today's children, who grew up with mobile technology from birth, worse at reading emotions and picking up cues from people's faces than children who didn't grow up with tablets and smartphones? A new UCLA psychology study suggests today's kids are all right.




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Immunity of recovered COVID-19 patients could cut risk of expanding economic activity

New modeling of coronavirus behavior suggests that an intervention strategy based on shield immunity could reduce the risk of allowing the higher levels of human interaction needed to support expanded economic activity.




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Editorial: US healthcare must take a more proactive approach to prepare for future disasters

The COVID-19 pandemic has revealed major deficiencies and inequities in the US healthcare system, shining a spotlight on improvements that must be made to steel the country for future disasters, argues Maia.




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Scientists measured electrical conductivity of pure interfacial water

Skoltech scientists in collaboration with researchers from the University of Stuttgart, the Karlsruhe Institute of Technology and the Russian Quantum Center achieved the first systematic experimental measurements of the electrical conductivity of pure interfacial water, hence producing new results significantly extending our knowledge of interfacial water.




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Olanzapine may help control nausea, vomiting in patients with advanced cancer

Olanzapine, a generic drug used to treat nervous, emotional and mental conditions, also may help patients with advanced cancer successfully manage nausea and vomiting unrelated to chemotherapy. These are the findings of a study published Thursday, May 7, 2020 in JAMA Oncology.




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Gemini gets lucky and takes a deep dive into Jupiter's clouds

Researchers using a technique known as 'lucky imaging' with the Gemini North telescope on Hawaii's Maunakea have collected some of the highest resolution images of Jupiter ever obtained from the ground. These images are part of a multi-year joint observing program with the Hubble Space Telescope in support of NASA's Juno mission.




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Telescopes and spacecraft join forces to probe deep into Jupiter's atmosphere

NASA's Hubble Space Telescope and the ground-based Gemini Observatory in Hawaii have teamed up with the Juno spacecraft to probe the mightiest storms in the solar system, taking place more than 500 million miles away on the giant planet Jupiter.




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Treatment for opioid use disorder is rare in hospitals, study finds

Despite a national opioid-related overdose epidemic that continues to claim tens of thousands of lives annually, a new nationwide study shows that a scant proportion of hospitalized patients with opioid use disorder receive proven life-saving medications both during and after they're discharged.




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By the third day most with COVID-19 lose sense of smell

The loss of the sense of smell and taste are early indicators of possible COVID-19 infection along with symptoms of respiratory distress. These prognostic markers might assist in determining use of antiviral treatments currently being used and tested on COVID-19 patients.




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Dendrimers finally have what it takes to break into the laser scene

A team including researchers from the University of Tsukuba has produced a family of dendrimers that form single-crystals and can harvest non-polarized light and transform it into polarized emission. The dendrimer crystals are both optically and mechanically stable to optical pumping, making them the first example of a crystalline material combining dendrimer properties and laser performance. The crystals are expected to have numerous applications in the field of laser optics, for example in displays.




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Ancient DNA paints genetic portrait of Andes civilizations

An international team of researchers including the University of Adelaide, has completed the first large-scale study of DNA belonging to ancient humans of the central Andes in South America and found early genetic differences between groups of nearby regions, and surprising genetic continuity over thousands of years.




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New invisibility concept and miniaturization of photonic circuits using ultrafast laser

Thanks to its unique three-dimensional manufacturing capacity, ultrafast laser writing is a prime candidate to meet the growing demand for the miniaturization of photonic circuitry, e.g., for scaling up optical quantum computers capacity. Towards this goal, scientists from Canada discovered a phenomenon related to the material electronic resonance that allows a much greater miniaturization of the laser written devices. Surprisingly, the new phenomenon allows other intriguing applications such as a new concept of invisibility.




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Potentially fatal combinations of humidity and heat are emerging across the globe

A new study has identified thousands of incidents of previously rare or unprecedented extreme heat/humidity combinations in parts of Asia, Africa, Australia, South America and North America, including in the US Gulf Coast region.




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First simulation of a full-sized mitochondrial membrane

Scientists from the University of Groningen have developed a method that combines different resolution levels in a computer simulation of biological membranes. Their algorithm backmaps a large-scale model that includes features, such as membrane curvature, to its corresponding coarse-grained molecular model. This has allowed them to zoom in on toxin-induced membrane budding and to simulate a full-sized mitochondrial lipid membrane. Their approach opens the way to whole-cell simulations at a molecular level.




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Computer vision helps SLAC scientists study lithium ion batteries

New machine learning methods bring insights into how lithium ion batteries degrade, and show it's more complicated than many thought.




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Flies sleep when need arises to adapt to new situations

Researchers at Washington University School of Medicine in St. Louis have found that flies sleep more when they can't fly, possibly because sleeping helps them adapt to a challenging new situation.




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Canadian study finds temperature, latitude not associated with COVID-19 spread

Temperature and latitude do not appear to be associated with the spread of coronavirus disease 2019 (COVID-19), according to a study of many countries published in CMAJ (Canadian Medical Association Journal), but school closures and other public health measures are having a positive effect.




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A pioneering study into the description of the architecture of a new standard for telecommunications

The International Telecommunication Union (ITU) is a United Nations Organization agency commissioned to regulate international telecommunications between different operating administrations and businesses. Pursuant to specific recommendations by this organization, on 1 July, standard Y.3172, an architecture for machine learning in future networks (5G and beyond), was approved for telecommunications networks.




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Scientists have created new nanocomposite from gold and titanium oxide

ITMO University researchers together with their colleagues from France and the USA have demonstrated how a femtosecond laser can be used to tune the structure and nanocomposite properties for titanium dioxide films filled with gold nanoparticles.




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NTU Singapore scientists develop sustainable way to extract chitin from prawn shells

Scientists at Nanyang Technological University, Singapore (NTU Singapore) have developed a green way to create chitin, by using two forms of food waste - prawn shells and discarded fruit - and fermenting them.




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Stretched beyond the limits

It's a common phenomenon we know from cracked sneakers and burst tyres: worn-out materials can cause anything from mild annoyance to fatal accidents. But while fatigue is well understood in synthetic materials, we know much less about such processes in mammalian tissue. An international team led by HITS researchers has shown that mechanical stress can similarly deteriorate collagen tissue. The findings might help to advance material research and biomedicine.




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Like a molecular knob: That is how a gene controls the electrical activity of the brain

Its name is Foxg1, it is a gene, and its unprecedented role is the protagonist of the discovery just published on the journal Cerebral Cortex. Foxg1 was already known for being a "master gene" able to coordinate the action of hundreds of other genes. As this new study reports, the "excitability" of neurons, namely their ability to respond to stimuli, communicating between each other and carrying out all their tasks, also depends on this gene.




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Hydrogen blamed for interfering with nickelate superconductors synthesis

Prof. ZHONG Zhicheng's team at the Ningbo Institute of Materials Technology and Engineering has investigated the electronic structure of the recently discovered nickelate superconductors NdNiO2. They successfully explained the experimental difficulties in synthesizing superconducting nickelates, in cooperation with Prof. Karsten Held at Vienna University of Technology.




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International research improves quality of CT scan imagery

Computerized tomography (CT) is one of the most effective medical tests for analysing the effects of many illnesses, including COVID-19. An international team has developed a new method that improves the quality of the images obtained from CT scans. The algorithm, tested on simulated data, enables them to distinguish different body's tissue types better and opens the door to lowering the doses of radiation to which patients are exposed during this type of test.




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Neighborhood and cognitive performance in middle-age: Does racial residential segregation matter?

A study at Columbia University Mailman School of Public Health found that black subjects who were exposed to highly segregated neighborhoods in young adulthood exhibited worse performance in cognitive skills in mid-life. This outcome may explain black-white disparities in dementia risk at older age.




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Epithelial GPS: Position of RNAi machinery is associated with epithelial identity

Researchers at the Medical University of South Carolina show in a new report that the RNA interference machinery, normally thought to reside in the nucleus or cytoplasm, predominantly localizes to these apical junctions and influences cell biology in the colon. Interestingly, in colon tumors, this localization is dysregulated and may shift the balance of RNAs to promote tumorigenesis.




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Seahorse and pipefish study by CCNY opens window to marine genetic diversity May 08, 2020

The direction of ocean currents can determine the direction of gene flow in rafting species, but this depends on species traits that allow for rafting propensity. This is according to a City College of New York study focusing on seahorse and pipefish species. And it could explain how high genetic diversity can contribute to extinction in small populations.




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Charity warns of 'mental illness timebomb' as calls increase by 200%

The number of callers to the charity SANE’s telephone helpline has increased by 200 percent since the lockdown began.




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UK Weather Forecast: A fine evening with clear skies & late, low sunlight

A fine end to the day with late sunshine & clear skies




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Four-year-old with cancer reunited with father after seven weeks kept apart in lockdown

Mila Sneddon hasn't seen her father in seven weeks in order to keep her safe during coronavirus lockdown.




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'Our souls are coming to the fore': The impact of pandemic on faith

Though each religion has faced different challenge, they share the view the lockdown has presented us with insight we might not have had.




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UK Weather Forecast: A chilly night with a slight frost in the east

Cold enough for a slight frost in places




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People want to see green spaces prioritised after lockdown – poll

Survey finds people are appreciating their local parks, countryside and green belt more.




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Portrait of Dame Vera Lynn unveiled to mark VE Day

The oil on canvas painting is entitled The Enduring Sweetheart.




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Woman charged with murder of church warden in Co-op attack

Zara Anne Radcliffe, 29, will appear in court accused of murdering 88-year-old John Rees and the attempted murder of three others.




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'He spat at me and said have some of my corona': Policing Britain during the coronavirus lockdown

ITV Tonight is out with Merseyside Police to investigate the extraordinary impact the pandemic is having on their ability to combat crime.




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A warm day with plenty of sunshine for most of the country

Temperatures will reach highs of 23 Celsius (73F) and it will feel noticeably warmer along North Sea coasts.




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At least eight dead and thousands taken to hospital after chemical leak in India

The incident led to panic among locals within a three-kilometre radius.




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People from black backgrounds four times more likely to die from virus than people from white backgrounds, ONS finds

People from black backgrounds are four times more likely to die from coronavirus than people from white backgrounds, new statistics suggest.




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Lockdown: Any easing of coronavirus restrictions in England will be 'very limited', No 10 says

The government will move with "maximum caution" when lifting coronavirus lockdown restrictions in England, Number 10 has said.




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How effective will the UK Covid-19 contact tracing app be and will it protect your privacy?

Questions remain over the viability of the coronavirus contact tracing app that has been developed by the NHS's digital department, NHSX.




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PM will set out roadmap on Sunday to easing lockdown 'with sensible changes' in England, Dominic Raab confirms

The briefing comes just hours after Scotland's First Minister has said the lockdown in Scotland should be extended.




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Spread of coronavirus in hospitals and care homes is the big problem, writes Robert Peston

In the community, the rate of transmission is probably as low as 0.5/0.6, which means its progress through the population has been arrested.




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World War Two veteran, 98, with lung condition recovers from coronavirus

Douglas Moore, who also has a lung condition, received a round of applause as he was discharged from Kettering General Hospital.