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Newron ditches sarizotan program after pivotal trial flop, sees shares crater

Newron will terminate work on its experimental Rett syndrome drug sarizotan after a complete failure in its pivotal STARS trial.




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Alnylam, Vir plan year-end trial of new RNAi COVID-19 antiviral

Alnylam and Vir Biotechnology have identified an anti-SARS-CoV-2 development candidate, putting them on track to start testing the inhaled RNAi treatment for COVID-19 in humans around the end of the year.




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Moderna eyes 'early summer' start for phase 3 COVID-19 vaccine trial

Moderna is finalizing the protocol for a phase 3 trial of its COVID-19 vaccine with a view to starting the study early in the summer. The establishment of the timeline, which follows FDA clearance to run a phase 2 trial, puts Moderna on track to win approval for its mRNA vaccine mRNA-1273 next year.




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Editorial: L.A.'s trails and parks are reopening. C'mon, people, don't screw it up this time

For goodness sake, if you're going to hike, wear a mask.




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Editorial: California was ready for a recession, but nothing could have prepared it for coronavirus

The good news: The state is far better prepared to meet this challenge than it was a decade ago. The bad news: It will need help from the feds, and a lot of it.




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All 10 family members in this house got COVID-19. Their patriarch didn't survive

The Ramirezes never thought the coronavirus would get them. They took every precaution, but the virus still found its way into their home. Over the course of days, each member of the 10-person household became infected. Three were hospitalized. And one, the family patriarch, died.




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Most California counties fall short of reopening criteria as coronavirus cases climb

The vast majority of California isn't close to meeting Gov. Gavin Newsom's reopening requirements, a Times analysis finds.




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A phase two trial and a June goal: This week's updates on the race for a coronavirus vaccine

Experts caution that even promising early results don’t guarantee that vaccines will be widely available anytime soon.




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Parasite-killing drug ivermectin heads into coronavirus trials




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Presentation Materials of Sustainability Meeting




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Presentation Materials of Financial Results for 3rd Quarter of Fiscal Year 2019 (Slides & Notes)




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Bacterial physiology: Another brick in the wall




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COVID-19: WHO launches Global Mega Trial with 4 promising drugs

The Global Mega Trial by WHO named Solidarity will include the study and testing of 4 promising drugs in order to develop an antidote of Coronavirus.




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MCU-induced mitochondrial calcium uptake promotes mitochondrial biogenesis and colorectal cancer growth




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Erianin, a novel dibenzyl compound in Dendrobium extract, inhibits lung cancer cell growth and migration via calcium/calmodulin-dependent ferroptosis




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Cadmium isotope fractionation reveals genetic variation in Cd uptake and translocation by <i>Theobroma cacao</i> and role of natural resistance-associated macrophage protein 5 and heavy metal ATPase-family transporters




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A pentaploid-based linkage map of the ancestral octoploid strawberry <i>Fragaria virginiana</i> reveals instances of sporadic hyper-recombination




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Concurrent germline and somatic pathogenic BAP1 variants in a patient with metastatic bladder cancer




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<i>ATP7B</i> variant c.1934T &gt; G p.Met645Arg causes Wilson disease by promoting exon 6 skipping




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Challenges in returning results in a genomic medicine implementation study: the Return of Actionable Variants Empirical (RAVE) study




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Larger bacterial populations evolve heavier fitness trade-offs and undergo greater ecological specialization




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Hydrocortisone and bronchopulmonary dysplasia: variables associated with response in premature infants




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Natural genetic variation in Stim1 creates stroke in the spontaneously hypertensive rat




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Nature Materials




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GCA relapse common in ustekinumab trial




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A novel vaccine target for malaria




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Editorial Expression of Concern: Exploring the quantum speed limit with computer games




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Gamma-glutamyltransferase, arterial remodeling and prehypertension in a healthy population at low cardiometabolic risk




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Effects of chronic type 5 phosphodiesterase inhibition on penile microvascular reactivity in hypertensive patients with erectile dysfunction: a randomized crossover placebo-controlled trial




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Cyanobacterial in vivo solar hydrogen production using a photosystem I–hydrogenase (PsaD-HoxYH) fusion complex




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Various Faculty Position (Professor, Associate Professor and Assistant Professor/Lecturer) at School of Materials Science and Engineering , Southeast University (SEU)

About us

Southeast University (SEU), located at Nanjing, is a prestigious higher education institution with its origin traced back to 1902. As one of the national key universities under direct administration of the Ministry of Education of China and jointly established with Jiangsu Province, it is selected in various programs, such National “Project 211” , “Program 985” and “Class A first-rate world universities” sponsored by the Central Government to build world-class universities.

*M…




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Various Faculty Position (Professor, Associate Professor and Assistant Professor/Lecturer) at School of Materials Science and Engineering , Southeast University (SEU)

About us

Southeast University (SEU), located at Nanjing, is a prestigious higher education institution with its origin traced back to 1902. As one of the national key universities under direct administration of the Ministry of Education of China and jointly established with Jiangsu Province, it is selected in various programs, such National “Project 211” , “Program 985” and “Class A first-rate world universities” sponsored by the Central Government to build world-class universities.

*M…




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Various Faculty Position (Professor, Associate Professor and Assistant Professor/Lecturer) at School of Materials Science and Engineering , Southeast University (SEU)

About us

Southeast University (SEU), located at Nanjing, is a prestigious higher education institution with its origin traced back to 1902. As one of the national key universities under direct administration of the Ministry of Education of China and jointly established with Jiangsu Province, it is selected in various programs, such National “Project 211” , “Program 985” and “Class A first-rate world universities” sponsored by the Central Government to build world-class universities.

*M…




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Clinical utility of serial analysis of circulating tumour cells for detection of minimal residual disease of metastatic nasopharyngeal carcinoma




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The untapped potential of ascites in ovarian cancer research and treatment




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Does multiparametric imaging with <sup>18</sup>F-FDG-PET/MRI capture spatial variation in immunohistochemical cancer biomarkers in head and neck squamous cell carcinoma?




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Clinical and radiographic evaluation of indirect pulp treatment of young permanent molars using photo-activated oral disinfection versus calcium hydroxide: a randomized controlled pilot trial




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Author Correction: A complete domain-to-species taxonomy for Bacteria and Archaea




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Surrogate endpoints for overall survival for patients with metastatic hormone-sensitive prostate cancer in the CHAARTED trial




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CMV-independent increase in CD27−CD28+ CD8+ EMRA T cells is inversely related to mortality in octogenarians




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Phase I trial of maintenance selinexor after allogeneic hematopoietic stem cell transplantation for patients with acute myeloid leukemia and myelodysplastic syndrome




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Donor-derived DNA variability in fingernails of acute myeloid leukemia patients after allogeneic hematopoietic stem cell transplantation detected by direct PCR




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Differential effectiveness of tyrosine kinase inhibitors in 2D/3D culture according to cell differentiation, p53 status and mitochondrial respiration in liver cancer cells




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Genocea's mark on malaria

Genocea has identified an immunological imprint in patients with malaria and is using a $1.2 million grant from the Gates Foundation to turn the findings into a vaccine.




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TMB: a promising immune-response biomarker, and potential spearhead in advancing targeted therapy trials




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Head-to-head trials in inflammatory bowel disease: past, present and future




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Colons or semi-colons: punctuating the regional variation of intestinal microbial–immune interactions




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Correction: Ketamine metabolites, clinical response, and gamma power in a randomized, placebo-controlled, crossover trial for treatment-resistant major depression




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Δ<sup>9</sup>-Tetrahydrocannabinol (THC) impairs visual working memory performance: a randomized crossover trial




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Author Correction: Vitamin lipid nanoparticles enable adoptive macrophage transfer for the treatment of multidrug-resistant bacterial sepsis