all Defying all the impossibilities in politics, Revanth Reddy makes it as Telangana CM By www.thehindu.com Published On :: Tue, 05 Dec 2023 19:05:45 +0530 Always willing to take the risk, he started his political career in the Legislature as an independent candidate in the Legislative Council Full Article Telangana
all Severe cyclone Michaung makes landfall in Andhra Pradesh, wreaks havoc By www.thehindu.com Published On :: Tue, 05 Dec 2023 19:17:59 +0530 Heavy rain and high-velocity winds with a maximum sustained speed of 90-100 kmph lash coastal town of Bapatla, villages; three killed in rain-related accidents; power supply affected in many areas; cyclone moving towards north, say officials Full Article Andhra Pradesh
all Hundreds of govt. employees mobilised for PM Modi’s Kashmir rally By www.thehindu.com Published On :: Mon, 04 Mar 2024 19:11:40 +0530 It is reported that as many as 7,000 employees from 13 departments will attend the PM’s rally in Srinagar’s Bakshi Stadium Full Article Other States
all BRS names candidates for four Lok Sabha seats, fields Koppula Eshwar from Peddapalli By www.thehindu.com Published On :: Mon, 04 Mar 2024 20:01:03 +0530 Party president KCR holds meeting with leaders of Mahabubabad, Khammam LS seats Full Article Telangana
all Parliamentary Panel highlights significant delays in installation of telemetry systems in critical flood-prone areas By www.thehindu.com Published On :: Sat, 27 Jul 2024 14:08:49 +0530 The Committee's report on the performance audit of schemes for flood control and forecasting underscores the need for urgent action to ensure timely and effective flood management Full Article Sikkim
all Deeply concerning: Usha slams executive committee members for not felicitating Olympic medallists By www.thehindu.com Published On :: Mon, 30 Sep 2024 14:43:41 +0530 India secured six medals, including two historic bronze by young shooter Manu Bhaker, but Usha said the "EC does not want to celebrate their success" and it makes her "very sad." Full Article Other Sports
all Is football messing up women’s basketball in Malappuram? By www.thehindu.com Published On :: Tue, 01 Oct 2024 04:37:00 +0530 For the second year in a row, Malappuram District could not field a team in the Kerala State senior basketball championship which begins here on Tuesday. Full Article Sport
all All set for the first moves in the second edition of Global Chess League By www.thehindu.com Published On :: Wed, 02 Oct 2024 20:47:16 +0530 Full Article Other Sports
all Denmark Open badminton: Indian challenge ends in women’s and mixed doubles By www.thehindu.com Published On :: Wed, 16 Oct 2024 16:52:19 +0530 Both the Indian pairs is action — Treesa Jolly and Gayatri Gopichand (women’s doubles) and B Summeth Reddy and N Sikki Reddy (mixed doubles) — suffered heartbreak three-game defeats in their opening contests Full Article Other Sports
all We have to go all the way back to Karpov and Kasparov on the top two boards to find something like India’s dominance: Peter Svidler By www.thehindu.com Published On :: Sat, 19 Oct 2024 00:59:03 +0530 In this chat, Russian GM Svidler talks about India’s historic Olympiad, his experience of coaching Praggnanandhaa, his love affair with Test cricket and his assessment of the Global Chess League, not just as a chess player but also as a cricket fan who follows the IPL Full Article Other Sports
all Deepika bags her fifth silver at Archery World Cup Final; Dhiraj falls early By www.thehindu.com Published On :: Mon, 21 Oct 2024 11:18:38 +0530 It was Deepika's ninth appearance at the World Cup Final where she has also bagged a bronze Full Article Other Sports
all I will be really, really surprised if Gukesh doesn’t win the World title: Anish Giri By www.thehindu.com Published On :: Sat, 26 Oct 2024 00:20:36 +0530 Grandmaster Giri — the 15th strongest chess player of all time — previews the World championship match, clears up a misconception about his style, and talks about the Candidates cycle, the Olympiad, the Global Chess League and Nihal Sarin’s prodigious talent Full Article Other Sports
all Chennai Grandmasters | Arjun rallies to post a win over Vidit on opening day By www.thehindu.com Published On :: Tue, 05 Nov 2024 20:53:34 +0530 Full Article Other Sports
all Designated terrorist Arsh Dalla arrested by Canadian police after shooting incident, say sources By www.thehindu.com Published On :: Sun, 10 Nov 2024 18:33:52 +0530 Though the police in Canada did not disclose the arrested person’s identity, sources in New Delhi claimed that he was believed to be Arsh Dalla, who ran terror modules on behalf of Hardeep Singh Nijjar. Full Article World
all Israel urges fans to skip France-Israel football match in Paris By www.thehindu.com Published On :: Sun, 10 Nov 2024 23:39:53 +0530 The National Security Council called on Israelis to “avoid attending sports games/cultural events involving Israelis Full Article World
all Students foil Awami League rally in Dhaka By www.thehindu.com Published On :: Mon, 11 Nov 2024 01:40:35 +0530 Eyewitnesses said activists of Anti-Discrimination Student Movement and several other political groups assembled at Noor Hossain Chattar, or Zero Point, near the Awami League’s central office Full Article World
all After storm over allegations, Australia Today clarifies ban was by Meta platforms, not Canadian government By www.thehindu.com Published On :: Mon, 11 Nov 2024 21:36:13 +0530 The Ministry of External Affairs, which had slammed Canada over the allegations last week, has been silent over clarification Full Article India
all Georgia President calls for fresh election after contested vote By www.thehindu.com Published On :: Mon, 11 Nov 2024 22:57:55 +0530 Georgian President Salome Zurabishvili calls for fresh elections amid allegations of electoral fraud, sparking crisis and international concern Full Article World
all Thousands rally in Georgia to question the vote and demand a new election By www.thehindu.com Published On :: Tue, 12 Nov 2024 02:25:38 +0530 The protesters waved Georgian and European Union flags and gathered outside the Georgian parliament Full Article World
all Sri Lanka’s multi-ethnic east reflects challenges facing Anura Kumara Dissanayake By www.thehindu.com Published On :: Tue, 12 Nov 2024 20:31:14 +0530 Voters in Ampara district voice hope, skepticism ahead of November 14 parliamentary polls Full Article World
all Flood victims of Vijayawada: People of all regions should come forward to support them, says Andhra Pradesh CM Chandrababu Naidu By www.thehindu.com Published On :: Sat, 02 Nov 2024 14:49:56 +0530 CM Chandrababu Naidu said moral and financial support for victims of natural calamities would instill confidence among them Full Article Andhra Pradesh
all Mission for pothole-free roads: Andhra Pradesh CM Chandrababu Naidu launches project at Anakapalli By www.thehindu.com Published On :: Sat, 02 Nov 2024 15:25:24 +0530 Pothole repairs, jungle clearance and road maintenance works will be taken up with a Budget of ₹861 crore Full Article Andhra Pradesh
all Tests to assess uranium availability: villagers of Kappatralla, Devanakonda raise voice against Centre’s permission By www.thehindu.com Published On :: Sun, 03 Nov 2024 11:49:11 +0530 The villagers fear losing their lands and livelihood and also adverse affects of uranium mining on their lives Full Article Andhra Pradesh
all SAAP Chairman urges Chief Minister to re-allot land in Visakhapatnam By www.thehindu.com Published On :: Tue, 05 Nov 2024 09:03:04 +0530 The land, meant for introducing water games, was used by former Chief Minister Y.S. Jagan Mohan Reddy for constructing a helipad for his palace, Ravi Naidu says Full Article Andhra Pradesh
all A.P. government appoints Inquiry Authority to probe role of revenue officers in alleged land scam in Vizianagaram By www.thehindu.com Published On :: Wed, 06 Nov 2024 18:44:59 +0530 Revenue Department Special Chief Secretary directs the Inquiring Authority to submit the inquiry report within a period of six weeks Full Article Andhra Pradesh
all Aurobindo Pharma Foundation’s 108 ambulance service failed to save lives in Andhra Pradesh, alleges TDP MLA By www.thehindu.com Published On :: Wed, 06 Nov 2024 22:23:12 +0530 Somireddy Chandra Mohan Reddy alleges corruption and inefficiency, claims the emergency service provider failed to move critically ill patients to hospitals on time, particularly during golden hour Full Article Andhra Pradesh
all Quality education for all is our aim, says A.P. HRD Minister Nara Lokesh By www.thehindu.com Published On :: Thu, 07 Nov 2024 20:05:15 +0530 Full Article Andhra Pradesh
all Hunt continues for tiger in Nallamala forest By www.thehindu.com Published On :: Fri, 08 Nov 2024 08:22:46 +0530 Full Article Andhra Pradesh
all Understanding regression analysis [electronic resource] / Michael Patrick Allen By darius.uleth.ca Published On :: New York : Plenum Press, 1997 Full Article
all The World War I databook : the essential facts and figures for all the combatants / John Ellis & Michael Cox By darius.uleth.ca Published On :: London : Aurum, 2001 Full Article
all Nanocubic cobalt-containing Prussian blue analogue-derived carbon-coated CoFe alloy nanoparticles for noninvasive uric acid sensing By pubs.rsc.org Published On :: Anal. Methods, 2024, Advance ArticleDOI: 10.1039/D4AY00121D, PaperYunting Qin, Dan Xiao, Xilan Gao, Xicui Zhang, Yanxue XuThis work describes an electrochemical sensor for the fast noninvasive detection of uric acid (UA) in saliva.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
all A reaction based carbazole–indolium conjugate probe for the selective detection of environmentally toxic ions By pubs.rsc.org Published On :: Anal. Methods, 2024, Advance ArticleDOI: 10.1039/D4AY00301B, PaperJayasudha Palanisamy, Mansour K. Gatasheh, Ashraf Atef HatamlehCarbazole–indolium based colorimetric probe was designed for detecting cyanide ions in various water samples. An outstanding response was shown by paper test strips prepared using the probe for the easy detection of cyanide in real time.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
all Proximity hybridization based “turn-on” DNA tweezer for accurate and enzyme-free small extracellular vesicles analysis By pubs.rsc.org Published On :: Anal. Methods, 2024, Accepted ManuscriptDOI: 10.1039/D4AY00487F, PaperJinlin Wu, Xi Mei, Xiaoqin Zhan, Fang Liu, Dongfang LiuSmall extracellular vesicles (sEVs) are a type of extracellular vesicles that carry many types of molecular information. The identification of sEVs is essential for the non-invasive detection and treatment of...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
all Losing a friend, virtually By www.thehindubusinessline.com Published On :: Mon, 03 Jun 2013 13:04:35 +0530 Full Article R Dinakaran
all Last mile woes: On inflation data and the challenges By www.thehindu.com Published On :: Sat, 14 Sep 2024 00:20:00 +0530 Inflation should not be allowed to undermine the economic momentum Full Article Editorial
all Allow for deliberation: On the legitimate demands of Ladakh By www.thehindu.com Published On :: Tue, 22 Oct 2024 00:15:00 +0530 The lack of a legislature and regional autonomy in Ladakh has led to the current protests Full Article Editorial
all Lead optimisation of OXS007417: in vivo PK profile and hERG liability modulation to optimise a small molecule differentiation agent for the potential treatment of acute myeloid leukaemia By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3495-3506DOI: 10.1039/D4MD00275J, Research Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Thomas J. Cogswell, Laia Josa-Culleré, David Zimmer, Sébastien R. G. Galan, Morgan Jay-Smith, Kate S. Harris, Carole J. R. Bataille, Thomas R. Jackson, Douzi Zhang, Stephen G. Davies, Paresh Vyas, Thomas A. Milne, Graham M. Wynne, Angela J. RussellThe optimisation of a class of AML differentiation agents is described to show improved potency, solubility and stability, reduced off target toxicity, and tumour regression in a murine model in vivo.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
all A comprehensive apoptotic assessment of niloticin in cervical cancer cells: a tirucallane-type triterpenoid from Aphanamixis polystachya (Wall.) Parker By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3444-3459DOI: 10.1039/D4MD00318G, Research ArticleAnuja Gracy Joseph, Mohanan Biji, Vishnu Priya Murali, Daisy R. Sherin, Alisha Valsan, Vimalkumar P. Sukumaran, Kokkuvayil Vasu Radhakrishnan, Kaustabh Kumar MaitiNiloticin, a triterpenoid from Aphanamixis polystachya, induces apoptosis in HeLa cells which is primarily validated through in silico analysis and subsequently in vitro apoptotic evaluation by modulating the apoptotic proteins.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
all SLL-1A-16 suppresses proliferation and induces autophagy in non-small-cell lung cancer cells via the AKT/mTOR signaling pathway By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3460-3468DOI: 10.1039/D4MD00405A, Research ArticleXiaoqin Luo, Jin Wang, Ruichang Wang, Jiabing Lian, Mengnan Guo, Hongrui Zhou, Mengxue Zhang, Zhe Yang, Xiaolong Li, Xianran He, Xiuli BiSchematic of proposed mechanism for the treatment of the SLL-1A-16 inhibiting the proliferation in NSCLC.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
all Design, synthesis and biological evaluation of a novel PSMA–PI3K small molecule drug conjugate By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3485-3494DOI: 10.1039/D4MD00246F, Research ArticleShouguo Peng, Haixia Li, Weilu Cui, Tianning Xiong, Jiaqi Hu, Haixiang Qi, Songwen Lin, Deyu Wu, Ming Ji, Heng XuA novel PSMA–PI3K small molecule drug conjugate has been prepared, highlighting its potential in targeted cancer therapy.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
all Next-generation EGFR tyrosine kinase inhibitors to overcome C797S mutation in non-small cell lung cancer (2019–2024) By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3371-3394DOI: 10.1039/D4MD00384E, Review ArticleDebasis Das, Lingzhi Xie, Jian HongProspects of novel fourth-generation EGFR-TKIs overcoming C797S-mediated resistance in non-small cell lung cancer.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
all Rationally modified SNX-class Hsp90 inhibitors disrupt extracellular fibronectin assembly without intracellular Hsp90 activity By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3609-3615DOI: 10.1039/D4MD00501E, Research Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Gciniwe S. Mathenjwa, Abir Chakraborty, Abantika Chakraborty, Ronel Muller, Mathew P. Akerman, Moira L. Bode, Adrienne L. Edkins, Clinton G. L. VealeRationally modified Hsp90 inhibitors which retained of on-target activity but showed no engagement of intracellular Hsp90, or stimulation of the heat shock response, were found to significantly alter the extracellular fibronectin network.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
all Sidechain structure–activity relationships of cyclobutane-based small molecule αvβ3 antagonists By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3616-3624DOI: 10.1039/D4MD00306C, Research Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Adam Throup, Manar Saleh Zraikat, Andrew Gordon, Shohreh Jafarinejad Soumehsaraei, Kathrin D. Haase, Laurence H. Patterson, Patricia A. Cooper, Katherine Hanlon, Paul M. Loadman, Mark Sutherland, Steven D. Shnyder, Helen M. SheldrakeCyclobutanes provide a versatile scaffold for the synthesis of small molecule integrin antagonists with good metabolic stability and in vivo tolerability.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
all Therapeutic upregulation of DNA repair pathways: strategies and small molecule activators By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00673A, Review ArticleJuhyung Song, Cheoljun Park, Francis E. B. Cabanting, Yong Woong JunPotential therapeutic target proteins for upregulating DNA repair system are reviewed, along with reported small-molecule activators.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
all Design and synthesis of (E)-3-benzylideneindolin-2-one derivatives as potential allosteric inhibitors of Aurora A kinase By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4MD00373J, Research ArticleYongLai Jiao, Jie Zhong, Jin-Fang Xu, Shaobo Ning, Taigang Liang, Mingzhu Zhao, Jian ZhangThe mitotic kinase Aurora A, a pivotal regulator of cell cycle, is overexpressed in various cancers and has emerged as one of the most promising targets for anticancer drug discovery....The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
all Discovery of N-substituted-2-oxoindolin benzoylhydrazines as c-MET/SMO modulators in EGFRi-resistant non-small cell lung cancer By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00553H, Research ArticleStefano Tomassi, Benito Natale, Michele Roggia, Luisa Amato, Caterina De Rosa, Carminia Maria Della Corte, Emma Baglini, Giorgio Amendola, Anna Messere, Salvatore Di Maro, Elisabetta Barresi, Federico Da Settimo, Maria Letizia Trincavelli, Fortunato Ciardiello, Sabrina Taliani, Floriana Morgillo, Sandro CosconatiNon-small cell lung cancer (NSCLC), the leading cause of cancer-related mortality worldwide, poses a formidable challenge due to its heterogeneity and the emergence of resistance to targeted therapies.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
all NTK chief Seeman booked for alleged ‘derogatory remarks’ against Karunanidhi By www.thehindu.com Published On :: Fri, 08 Nov 2024 19:03:53 +0530 Full Article Tiruchirapalli
all Small-scale handloom park to come up at Sengunthapuram By www.thehindu.com Published On :: Fri, 08 Nov 2024 19:09:38 +0530 Ministers R. Gandhi and S.S. Sivashankar inspect the 13,205 sq. ft. site belonging to the Tamil Nadu Cotton Corporation at Sengunthapuram Full Article Tiruchirapalli
all Site identified for small-scale handloom park in Karur By www.thehindu.com Published On :: Sat, 09 Nov 2024 19:30:54 +0530 Full Article Tiruchirapalli
all 555: React Documentary, Front of the Front End, Fast Fallacy, and Best Practices By shoptalkshow.com Published On :: Mon, 06 Mar 2023 09:39:37 +0000 Reacting to the React.js documentary, is there still jobs for front of the front end anymore? The fast fallacy in frameworks, best practices, dealing with too much or too little isolation, and AI test generation. Full Article All Episodes applying for a job React Tests