The Braves made it clear that, individually, each of their prospects was available in exchange for J.T. Realmuto. But they were not willing to provide the volume of prospects or the MLB-experienced asset sought by the Marlins, who ended an offseason-long saga by dealing the All-Star catcher to the Phillies on Thursday.

At some point over the next six weeks, injuries, improvement or regression will inevitably alter the plan nearly every Major League club brings into Spring Training. The Braves must decide exactly how to round out their rotation and bullpen, but for now it looks like they won't have any position-player battles. Here's the first prediction of how Atlanta's Opening Day roster might look.

Here are the top players in each league who could get the opportunity to show what they can do at the highest level this year, perhaps even contending for Rookie of the Year honors

Here is a look at 10 Braves players sure to draw attention during this year's Spring Training.

The next five weeks will see lots of shuffling on Major League rosters. Here are the most intriguing positional battles on each of the 30 MLB clubs.

Braves manager Brian Snitker joked that he could almost detect a smile as he shared a phone conversation with Nick Markakis after the stoic outfielder re-signed with the club in January. Snitker and others actually saw that smile on Tuesday morning, when Markakis reported to Spring Training to begin his fifth season with the Braves and attempt to push the club past the rebuild he positively enriched through his leadership.

To those of a certain age, Frank Robinson was the definition of greatness, leadership and toughness. Well into his 70's and 80's, he carried himself with the confidence and unmistakable gait of a great athlete.

In outlining their plans to rebuild the Orioles following the least successful season in franchise history, new club officials routinely point to experience: They just did the same thing elsewhere.

Here's an early look at how the Orioles' 25-man roster could shape up on Opening Day.

The Orioles' crowded outfield mix gained another member on Monday when the team signed veteran Eric Young Jr. to a Minor League contract with an invitation to Spring Training.

Since the Rays debuted "the opener" last May, no fewer than eight teams have helped transform the concept from a fad into a mini-movement. Consider the Orioles a candidate to dive in next.

For Brandon Hyde, the days and weeks leading up to Tuesday were filled with phone calls to friends, to former colleagues, to mentors he's made across more than two decades in the game. A constant theme emerged from the ensuing chats: What, exactly, should Hyde expect from his first Spring Training as a big league manager?

As pitchers and catchers reported Tuesday to Ed Smith Stadium, it marked the end to an offseason of overhaul in Baltimore, and the dawn of a new era. The focus will shift even further, from the front office to the field, when the club's first full squad workouts commence on Monday.

As we inch closer and closer to Opening Day, we'll continue to take a position-by-position look at the Orioles roster options and remaining questions. Now that pitchers and catchers have officially reported to Spring Training, now feels like a good time to take a look behind the plate, where the Orioles have a ton of options but no clear answer.

With more than a dozen pitchers seemingly in the mix for bullpen jobs this spring, it'll take weeks of assessment before candidates for certain roles begin to emerge. Even the club's few veteran holdovers will have to wait. That includes Mychal Givens, who finished 2018 as the Orioles' closer and arrived at camp the overwhelming favorite to reclaim that job.

Wave him bye bye. A legendary voice of Orioles baseball is calling it a career. Joe Angel, beloved play-by-plan man and voice of the Orioles' radio broadcasts for nearly two decades, announced his retirement this week. The decision caps a 41-year career in the booth for Angel, 71, a fixture for 19 seasons across two stints in Baltimore.

Looking to preempt questions about his work ethic in a nightmare 2018 season, Chris Davis reported to Spring Training in Florida more than a week before Orioles position players were required to. That's when his efforts to rebound hit their first minor snag.

The Orioles' cloudy infield picture gained some clarity Saturday when the team signed veteran shortstop Alcides Escobar to a Minor League contract with an invitation to Spring Training.

Like so many pitchers in Major League camps, Orioles hurlers have extra sets of eyes on them this spring. The Edgertronic cameras, perched on tripods, are set about a stride's length beyond the backfield bullpen mounds at the club's Ed Smith Stadium complex, as conspicuous as the coaches standing cross-armed behind them.

The next five weeks will see lots of shuffling on Major League rosters. Here are the most intriguing positional battles on each of the 30 MLB clubs.

Orioles right-hander Hunter Harvey had hopped off a backfield mound at the club's Spring Training complex and exhaled. He was one of 14 pitchers scheduled to face hitters as part of the club's first full-squad workout on Monday, and now that he had, Harvey was asked to recall when was the last time he threw competitive pitches.

In holding their first full-squad workout on Monday, the Orioles ushered in the first official phase of a spring set to surprise. Fresh faces flood Ed Smith Stadium. Questions litter the roster. Battles abound at nearly every position.

Pitch clocks are set to make their Spring Training debuts this week, and it will be in games featuring hordes of players for whom playing on a timer is nothing new.

The ability to switch fuels for oxidation in response to changes in macronutrient composition of diet (metabolic flexibility) may be informative of individuals’ susceptibility to weight gain. Seventy-nine healthy, weight-stable participants underwent 24-h assessments of energy expenditure and respiratory quotient (RQ) in a whole-room calorimeter during energy balance (EBL) (50% carbohydrate, 30% fat) and then during 24-h fasting and three 200% overfeeding diets in a crossover design. Metabolic flexibility was defined as the change in 24-h RQ from EBL during fasting and standard overfeeding (STOF) (50% carbohydrate, 30% fat), high-fat overfeeding (HFOF) (60% fat, 20% carbohydrate), and high-carbohydrate overfeeding (HCOF) (75% carbohydrate, 5% fat) diets. Free-living weight change was assessed after 6 and 12 months. Compared with EBL, RQ decreased on average by 9% during fasting and by 4% during HFOF but increased by 4% during STOF and by 8% during HCOF. A smaller decrease in RQ, reflecting a smaller increase in lipid oxidation rate, during HFOF but not during the other diets predicted greater weight gain at both 6 and 12 months. An impaired metabolic flexibility to acute HFOF can identify individuals prone to weight gain, indicating that an individual’s capacity to oxidize dietary fat is a metabolic determinant of weight change.

The whitening and loss of brown adipose tissue (BAT) during obesity and aging promote metabolic disorders and related diseases. The imbalance of Ca²⁺ homeostasis accounts for the dysfunction and clearance of mitochondria during BAT whitening. Capsaicin, a dietary factor activating TRPV1, can inhibit obesity induced by high-fat diet (HFD), but whether capsaicin inhibits BAT loss and the underlying mechanism remain unclear. In this study, we determined that the inhibitory effects of capsaicin on HFD-induced obesity and BAT whitening were dependent on the participation of SIRT3, a critical mitochondrial deacetylase. SIRT3 also mediated all of the beneficial effects of capsaicin on alleviating reactive oxygen species generation, elevating mitochondrial activity, and restricting mitochondrial calcium overload induced by HFD. Mechanistically, SIRT3 inhibits mitochondrial calcium uniporter (MCU)-mediated mitochondrial calcium overload by reducing the H3K27ac level on the MCU promoter in an AMPK-dependent manner. In addition, HFD also inhibits AMPK activity to reduce SIRT3 expression, which could be reversed by capsaicin. Capsaicin intervention also inhibited aging-induced BAT whitening through this mechanism. In conclusion, this study emphasizes a critical role of the AMPK/SIRT3 pathway in the maintenance of BAT morphology and function and suggests that intervention in this pathway may be an effective target for preventing obesity- or age-related metabolic diseases.

The signing of veteran outfielder Michael Brantley by the Astros came a week after the Winter Meetings and only a few days before Christmas, meaning it didn't exactly garner much attention on national, or even local, news cycles. For the Astros, Brantley was exactly the player they needed at exactly the right price -- two years and $32 million -- and the kind of addition that should fire up the fanbase.

There won't be many roster battles when the Astros open camp later this week, and they won't be decided until the final days of the team's stay in West Palm Beach, Fla. Houston has an open competition for its fifth starter spot heading into Spring Training, and the club also has to sort out a crowded outfield and the final spots in the bullpen.

All eyes were on right-hander Forrest Whitley, MLB Pipeline's top pitching prospect, when he threw in the bullpen for the first time Friday in Major League camp. Astros manager AJ Hinch, assistant general manager Brandon Taubman and director of player development Pete Putila were all watching intently as Whitley threw 21 pitches -- fastballs, changeups and cutters.

Astros third baseman Alex Bregman continues to progress from the arthroscopic elbow surgery he had a month to remove bone chips.

The next five weeks will see lots of shuffling on Major League rosters. Here are the most intriguing positional battles on each of the 30 MLB clubs.

They wrestled with the decision to start a family for five years. It's something most young couples discuss at some point. Timing is important, and considering their busy lives, even more so for Astros pitcher Joe Smith and his wife, TV sports reporter Allie LaForce. The issue facing the couple is far more momentous than most others have to deal with -- one that's a matter of life and death.

It took only two words for Alex Bregman to send 9-year-old Jax Nystrom into a frenzy, but this kind of reaction -- young people freaking out at the slightest bit of attention from him -- has become commonplace for the Astros' All-Star third baseman.

Airbnb says it is laying off 25% of its workforce as it confronts a steep decline in global travel due to the new coronavirus pandemic. It’s a serious setback for the 12-year-old home-sharing company, which just a few months ago was...

Pan American Health Organization (PAHO) director, Dr Carissa Etienne, is warning that lifting COVID-19 restrictions too soon could accelerate the spread of the virus and open the door for a dramatic upsurge in countries of the region. The warning...

JERUSALEM (AP): Israeli Prime Minister Benjamin Netanyahu formally received the support of a majority of lawmakers to lead a new government yesterday, paving the way for a controversial power-sharing deal with rival-turned-partner Benny Gantz....

WASHINGTON (AP) — President Donald Trump, who’s taken to calling the US the “king” of ventilators, is making plans to ship 8,000 of the breathing machines to foreign countries by the end of July to help in their fight...

JAMAICA OLYMPIC Association (JOA) President Christopher Samuda believes that his sports administration experience will aid him in helping to finally shape a professional football league in the Caribbean. Concacaf announced Samuda’s appointment to...

ROSEAU, Dominica (CMC): A top West Indies Cricket Umpires Association (WICUA) official says regional umpires have also been heavily impacted by the cessation of cricket, stemming from the outbreak of the COVID-19 pandemic. Vivian Johnson, who...

BASSETERRE, St Kitts (CMC): ST KITTS AND Nevis Patriots have made some significant changes to their line-up for the upcoming Caribbean Premier League (CPL) season. Captain Carlos Brathwaite has gone to the Jamaica Tallawahs, while the Patriots have...

Western Bureau: A number of swimming officials in western Jamaica say that the region’s struggles with underdevelopment will continue even if the COVID-19 pandemic is brought under control. They say this is because they still lack proper pools to...

FORMER NATIONAL footballer Aldrick ‘Allie’ McNab is concerned about the effect of the COVID-19 pandemic on the Caribbean’s football development. The coronavirus has caused the postponement, suspension, and cancellation of a number of sporting...

Western Bureau: THE MOBAY City Run organisers have reconsidered the event’s cancellation. Organising committee chair­person Janet Silvera said on Sunday, the day the event was to have taken place, that the seventh staging of the 5K/10K Walk and Run...

Jamaica Football Federation (JFF) general secretary Dalton Wint says that any potential changes to the Concacaf hexagonal round for the FIFA World Cup qualifiers could present challenges to the nation’s aim of qualifying for Qatar 2022. Wint’s...

The UK’s austerity programme has disproportionately affected children and people with disabilities, says David Taylor-Robinson, a senior clinical lecturer in public health at the University of Liverpool. He joins us to discuss why the evidence shows the vulnerable are hit hardest by the cuts to public services, despite the UN conventions on...

One hundred years ago, Pennsylvanian surgeon Evan Kane penned a brief letter to JAMA in which he declared himself a rigorous proponent of the “benefic [sic] effects of the phonograph within the operating room.” Now David Bosenquet, a surgeon from University Hospital of Wales in Cardiff has written a Christmas editorial about the evidence for the...

Waiting times in theatre can be a source of friction – but is the delay due to mandatory anaesthetic faff around time (MAFAT), or AWOL surgeons? Elizabeth Travis, and orthopaedic house officer in New Zealand and colleagues, have been trying to create and evidence base to argue the toss, and she joins me now to discuss her study, Operating...

Until recently, hepatitis C screening was offered to people at increased risk of infection - such as intravenous drug users - but now, the US Centers for Disease Control and Prevention has recommended screening all people born between 1945 and 1965. Kenny Lin, associate professor of family medicine at Georgetown University in Washington, DC, and...

Multimorbidity presents a number of different challenges, for the patients living with the conditions, but also for the health professionals caring for them in systems that often are not designed with these more complex needs in mind. Emma Wallace, general practice lecturer, and Susan Smith, a professor of general practice at the Royal College of...

In our accompanying roundtable discussion,we hear views from a group of patients and clinicians based largely in the UK on the actions required  to advance  progress towards providing patient centred care. To extend the conversation we talked to members of the BMJ's international patient advisory panel and other patient advocates - and what...

Participants in our discussion on person centred care in January agreed that a change in culture and better use of technology could benefit both patients and doctors. At the roundtable: Fiona Godlee (chair), editor in chief, The BMJ Tessa Richards, senior editor, patient partnership, The BMJ Rosamund Snow, patient editor, The BMJ Navjoyt Ladher,...