A seal member for an aseptic coupling device includes a cross-sectional area including a first end portion, a middle portion, and a second end portion opposite the first end portion, the middle portion being thinner in radial dimension than the first and second end portions.

An apparatus includes a light foil device configured to move based on radiation pressure associated with light received by the light foil device. The apparatus includes a mechanism configured to transition between operational states in response to the movement of the light foil device, or includes a valve configured to control a flow of material through a conduit based, at least in part, on the movement of the light foil device.

In a processing machine including a processor having a processing blade and a receiver having a reception member and in which a blade edge of the processing blade and a reception portion, of the reception member, engage with each other to process a paper sheet therebetween, the processing blade is one processing blade selected from a blade group and is attached to the processor so as to be changeable to another processing blade of the blade group, reception portions of kinds corresponding to a plurality of kinds of the processing blades of the blade group are formed on the reception member, and the processing blade attached to the processor is positioned so as to be in a position where the blade edge is engageable with the reception portion of the corresponding kind.

A method for operating a processing system, in which product units of different formats are processed. The processing system contains a plurality of processing devices that are arranged one after the other in a processing line. In the event of a format changeover, certain component arrangements arranged in the processing system must be adapted to the new product format. In the event of an upcoming format change, a gap in the conveyed goods is generated while the conveying operation is maintained, wherein the gap in the conveyed goods runs through the processing system along the processing devices. As soon as the gap in the conveyed goods runs through a component arrangement to be adapted to the new format, the format is changed over at the component arrangement while the gap in the conveyed goods runs through the component arrangement.

The invention proposes a method for producing a printed product, in which a printed product, preferably produced in a forme-bound high-capacity printing process, in the form of a main product (2) or a subproduct is provided with an identification means which comprises a piece of individualizable product-specific information. At least two downstream individualization steps are performed, wherein the identification means allow the piece of information which is to be added in the at least two further downstream individualization steps to be associated with the respective product. Preferably, the new addressee-specific digital printed product comprises blog articles, preferably in the form of a blog insert, which is in turn preferably produced using digital printing. Identification means, for example in the form of ID tags (4, 4'), comprise not only the product-specific identification information but preferably also control information (31-36) which can be read by sensors on the handling devices (7-12) and hence directly control the handling of the respective product by this at least one handling device (7-12) and, in cooperation with inspection codes on the subproducts to be supplied, allow the correct supply to be inspected. The present invention also allows uninterrupted compilation of product packages for postal dispatch by virtue of the product sequence in the course of the conveying line comprising, at least in sections, a recurring succession of a respective one or more intermediate products partly individualized on an addressee-specific basis and at least one, preferably a plurality of, non-individualized standard intermediate products.

A sheet processing apparatus which is capable of completing a bound document containing appropriately Z-folded sheets when performing folding together with edge cutting and binding. The sheet processing apparatus controls a Z-folding process, a cutting process, and a binding process for a sheet. A first folding position from a free end of the sheet coincides with a position corresponding to half a width of the sheet excluding a cut width of the sheet a binding margin, when the Z-folding process, the cutting process, and the binding process are executed.

The post-processing device includes: a binding unit that forms a cut in a sheet stack and cuts a part of the sheet stack into a predetermined shape to form a tongue portion in the sheet stack, the tongue portion having a part where one end part of the tongue portion is not separated from the sheet stack, and binds the sheet stack by bending the tongue portion and inserting the other end part of the tongue portion into the cut; and a sheet stack transport unit that transports the sheet stack in an orientation such that the one end part of the tongue portion in the sheet stack bound by the binding unit is on a downstream side of the other end part of the tongue portion in the sheet stack transport direction.

A sheet processing apparatus 3 includes a position aligning section (61A, 61B), a holding section 53, and a processing section (38, 55). The position aligning section (61A, 61B) abuts the inner side or a fold of a sheet bundle (S2), which is formed by collecting a plurality of folded sheets (S1), to align the position of the folds of line plurality of folded sheets (S1). The holding section (53) holds the sheet bundle (S2) in which the position of the folds of the plurality of sheets (S1) has been aligned by the position aligning section (61A, 61B). The processing section (38, 55) performs a predetermined process on the sheet bundle (S2) held by the holding section 53.

According to an embodiment, there is provided a sheet processing apparatus includes a stacking unit that stacks a sheet conveyed thereto; a first alignment unit that aligns the sheet or a bundle of sheets stacked in the stacking unit in a sheet conveying direction; a second alignment unit that aligns the sheet or the bundle of sheets stacked in the stacking unit in a direction orthogonal to the sheet conveying direction; a pressing unit that presses the bundle of sheets at an end portion thereof on a predetermined one side; and a control unit that causes at least one of the first and second alignment units to execute an alignment operation during a press operation of the sheet or the bundle of sheets performed by the pressing unit.

A sheet processing device includes a clamp configured to clamp an edge portion of a sheet, the edge portion being on a side of an edge parallel to a direction in which the sheet has been conveyed; a first processing unit configured to perform a first process on the sheet at the side of the edge, the first processing unit being disposed at a first position; a second processing unit configured to perform a second process on the sheet at the side of the edge, the second processing unit being disposed at a second position that is different from the first position in a vertical direction; and a moving unit configured to move the clamp from the first position to the second position or vice versa so that the clamp moves on a loop passing through the first position and the second position.

According to one embodiment, a sheet post-processing apparatus includes a machine body, a first roller pair, a tray, a second roller pair, a driving unit, an inlet sensor, a receiving unit and a control unit. The inlet sensor is configured to detect presence or absence of the sheet in the first roller pair driven by the driving unit. The receiving unit is configured to receive, from an image forming apparatus, sheet length information in the sheet conveying direction of the sheet as a target to which the print job is applied. The control unit is configured to control the driving unit to rotate, if the sheet length information indicates special length and the inlet sensor detects a trailing end of the sheet, at least rollers of the second roller pair a predetermined number of times and stop the rollers, the second roller pair nipping the sheet.

The present invention is directed to providing a mechanism for allowing a user to easily take out print products discharged onto a plurality of sheet discharge trays in the discharge order. A control method for controlling a sheet processing apparatus for performing control to discharge sheets onto a plurality of sheet discharge trays includes storing, in a storage unit, the discharge order in which sheets have been discharged onto equal to or more than two sheet discharge trays by executing a job, and performing, upon reception of a take-out instruction for taking out in the discharge order the sheets discharged by executing the job, processing for allowing a user to take out the sheets discharged onto the equal to or more than two sheet discharge trays, in the discharge order stored in the storage unit.

A sheet processing apparatus includes a pair of squeezing members having a projection and a recess to engage each other, to squeeze a sheet bundle inserted therebetween in a direction of thickness of the sheet bundle, and a pressure applying unit to apply pressing force to the squeezing members to squeeze and bind the sheet bundle. The pressing force generated between the squeezing members by the pressure applying unit increases in strength as a relative distance between the squeezing members decreases.

A post-processing apparatus includes a processing tray, a conveyance portion, a staple unit, an operation portion, a mode switching portion, a cover, and an open/close detection portion. The staple unit, which has an automatic mode and a manual mode as processing modes for stapling processing, executes stapling processing for a paper sheet conveyed to the processing tray by the conveyance portion in the automatic mode, and executes stapling processing for a paper sheet stacked on the processing tray by a user in the manual mode. The cover is attached in an openable and closable manner so as to cover the operation portion when closed, and expose the operation portion when opened. While the open/close detection portion is detecting that the cover is opened, when the operation portion has received an operation for switching to the manual mode, the mode switching portion switches the automatic mode to the manual mode.

In a provided apparatus, an upper roller to be engaged with a sheet upper face and a lower roller to be engaged with a sheet lower face are arranged at a sheet discharging port in a manner capable of being pressure-contacted and being separated, the upper roller is formed with a large-diameter soft roll face and a small-diameter hard roll face, and a pressurization force of roller lifting-lowering means with which the upper roller is pressure-contacted to and is separated from the lower roller is switched to be high or low.

In a sheet storing apparatus of the present invention, a tailing end supporting member which temporarily supports a tailing end of a dropping sheet bundle is arranged between a discharging port of a processing tray to discharge the sheet bundle and the upmost sheet on a stack tray as being movable between an operating position above a sheet placement face and a waiting position outside the stack tray.

A sheet processing apparatus includes a projection forming unit configured to form a projection on a sheet. The projection is formed in the vicinity of a binding portion of a sheet bundle. When a succeeding sheet bundle is discharged on the sheet bundle in which the projection has been formed on a top surface thereof, the succeeding sheet bundle is stacked by moving on the already stacked sheet bundle without being caught by the binding portion of the already stacked sheet bundle as an end of the succeeding sheet bundle is guided by the projection.

A sheet processing apparatus and a method of controlling the same align sheets stacked on a stacking unit, by causing a first alignment member and a second alignment member to come into contact with edges of a sheet stacked on the stacking unit in a sheet width direction. In a case that a second sheet that is different from a first sheet stacked on the stacking unit is to be stacked on the first sheet and aligned using the first alignment member and the second alignment member, control is performed to discharge a partition sheet onto the first sheet stacked on the stacking unit.

A sheet processing apparatus including a stacking tray that stacks sheets, a conveying member that conveys a sheet to the stacking tray and discharges the sheet bundle from the stacking tray, wherein the conveying member includes a conveying roller and a conveying belt stretched by a plurality of stretch rollers, and a sheet processor that performs predetermined processing to the sheet bundle. When the conveying member conveys the sheet to the stacking tray, a part of the conveying belt that is not wound on the stretch roller contacts the conveying roller by moving the conveying belt as such a nip for conveying the sheet is formed. When the conveying member discharges the sheet bundle from the stacking tray, a part of the conveying belt that is wound on the stretch roller contacts the conveying roller by moving the conveying belt so that a nip for conveying the sheet is formed.

A sheet processing apparatus includes: a folding processing unit that folds a sheet by reversely rotating a second conveying member in a condition in which the sheet is held by a first and the second conveying members; a calculating unit that calculates an amount of deflection of the sheet held by the first and second conveying members from timings at which the sheet is detected by first and second detecting units disposed upstream of the first conveying member and downstream of the second conveying member and a distance between disposed positions of the first and second detecting units; and a control unit that sets, from the calculated amount of deflection of the sheet, an amount of conveyance for the first conveying member in a direction opposite to a sheet conveying direction in a condition in which the sheet is held by the first and second conveying members.

A mechanism capable of changing an upper limit number of sheets for a post-process is provided. To achieve this, a control method for controlling a sheet processing apparatus which performs the post-process for the sheets on which images are formed, comprising: storing, in a storage unit, the upper limit number of sheets to which the post-process can be performed; and changing the upper limit number of sheets stored in the storage unit is provided.

A puncher cylinder includes a puncher knife, the cylinder being arranged for cooperation with a paper web such that the cylinder when in use can be rolled longitudinally along and in contact with the paper web, punching holes in the paper web by way of the puncher knife. The holes are punched a longitudinal distance from each other essentially corresponding to the circumference of the cylinder. A system is further disclosed including the punching cylinder, as is a method utilizing the punching cylinder, and a newspaper partly produced by way of the punching cylinder.

A first discharging portion that discharges a sheet received from one of image forming apparatus and a second discharging portion discharges a sheet received from another image forming apparatus are disposed opposite each other to stack the sheets discharged in a common processing tray. A controller controls the first and second discharging portions when the sheets are continuously discharged by the first and second discharging portions, controls a timing when the sheets are discharged by the first discharging portion and the second discharging portion to the common processing tray such that a leading edge of the sheet discharged from one of the discharging portions abuts on a sheet surface in the downstream of a discharging direction below a leading edge of the sheet discharged from the other discharging portion.

An apparatus for processing sheets of different formats, the apparatus including a feeding device that feed sheets of different formats in a feeding direction one behind the other, and at a certain conveying speed, at least two collecting drums disposed downstream of the feeding device, the at least two collecting drums having cylindrical lateral surfaces that rotate about an axis of rotation, securing means for temporarily securing the fed sheets on a circumference of the at least two collecting drums, a drive device that drives the collecting drums in rotation at a circumferential speed that corresponds to the conveying speed of the feeding device, and a sensing device for sensing the sheets of different formats moving past is arranged along the conveying path and senses the leading edge of the sheets of different formats, as seen in the feeding direction, or markings applied to the sheets of different formats.

The present invention relates generally to a semiconductor device and, more specifically, to optimizing the creep-age distance of the power semiconductor device and a preparation method thereof. The power semiconductor device includes a chip mounting unit with a die paddle and a plurality of leads arranged side by side located close to one side edge of the die paddle in a non-equidistant manner, a semiconductor chip attached on the die paddle, and a plastic packaging body covering the die paddle, the semiconductor chip, where the plastic packing body includes a plastic extension portion covering at least a part of a lead shoulder of a lead to obtain better electrical safety distance between the terminals of the semiconductor device, thus voltage creep-age distance of the device is increased.

A land grid array (LGA) package including a substrate having a plurality of lands formed on a first surface of the substrate, a semiconductor chip mounted on a second surface of the substrate, a connection portion connecting the semiconductor chip and the substrate, and a support layer formed on part of a surface of a first land.

Maskless hybrid laser scribing and plasma etching wafer dicing processes are described. In an example, a method of dicing a semiconductor wafer having a front surface with a plurality of integrated circuits thereon and having a passivation layer disposed between and covering metal pillar/solder bump pairs of the integrated circuits involves laser scribing, without the use of a mask layer, the passivation layer to provide scribe lines exposing the semiconductor wafer. The method also involves plasma etching the semiconductor wafer through the scribe lines to singulate the integrated circuits, wherein the passivation layer protects the integrated circuits during at least a portion of the plasma etching. The method also involves thinning the passivation layer to partially expose the metal pillar/solder bump pairs of the integrated circuits.

An apparatus including a die including a dielectric material on a device side, an insulating layer surrounding a die area and embedding a thickness dimension of the die; and a carrier including a plurality of layers of conductive material disposed on the device side of the die, a first one of the layers of conductive materials being formed on the insulating layer and patterned into traces at least a portion of which are connected to respective contact points on the die. A method including disposing a die on a sacrificial substrate with a device side of the die opposite the sacrificial substrate; disposing a mold on the sacrificial substrate around; introducing an insulating material into a chase of the mold; removing the mold; forming a carrier on the insulating material adjacent a device side of a die; and separating the die and the carrier from the sacrificial substrate.

Methods for the fabrication of a Microelectromechanical Systems (“MEMS”) devices are provided, as are MEMS devices. In one embodiment, the MEMS device fabrication method includes forming at least one via opening extending into a substrate wafer, depositing a body of electrically-conductive material over the substrate wafer and into the via opening to produce a via, bonding the substrate wafer to a transducer wafer having an electrically-conductive transducer layer, and forming an electrical connection between the via and the electrically-conductive transducer layer. The substrate wafer is thinned to reveal the via through a bottom surface of the substrate wafer, and a backside conductor is produced over a bottom surface of the substrate wafer electrically coupled to the via.

A bump-on-trace (BOT) structure is described. The BOT structure includes a first work piece with a metal trace on a surface of the first work piece, wherein the metal trace has a first axis. The BOT structure further includes a second work piece with an elongated metal bump, wherein the elongated metal bump has a second axis, wherein the second axis is at a non-zero angle from the first axis. The BOT structure further includes a metal bump, wherein the metal bump electrically connects the metal trace and the elongated metal bump. A package having a BOT structure and a method of forming the BOT structure are also described.

An embodiment is an integrated circuit structure including a first die attached to a second die by a first connector. The first connector includes a solder joint portion between a first nickel-containing layer and a second nickel-containing layer, a first copper-containing layer between the first nickel-containing layer and the solder joint portion, and a second copper-containing layer between the second nickel-containing layer and the solder joint portion.

Systems, manufactures, methods and/or techniques for a merged fiducial for chip packages are described. According to some embodiments, an integrated circuit package may include a package substrate having a first side and a second side, a plurality of conductive traces coupled to the first side and a plurality of balls disposed on the second side. The balls may be adapted to electrically connect the laminate package to a circuit board. The integrated circuit package may include a plurality of ball pads disposed on the second side, the ball pads being adapted to electrically connect the plurality of balls to the plurality of conductive traces. One or more of the ball pads may be uniquely shaped when compared to the rest of the plurality of ball pads, optionally, to serve as a fiducial to designate an A1 pin or ball of the laminate package.

Methods, systems, and structures for detecting residual material on semiconductor wafers are provided. A method includes scanning a test structure including topographic features on a surface of a semiconductor wafer. The method further includes determining, based on the scanning, that the test structure includes an amount of a residual material of a sacrificial layer that exceeds a predetermined threshold.

Embodiments of a method for fabricating stacked microelectronic packages are provided, as are embodiments of a stacked microelectronic package. In one embodiment, the method includes arranging microelectronic device panels in a panel stack. Each microelectronic device panel includes a plurality of microelectronic devices and a plurality of package edge conductors extending therefrom. Trenches are formed in the panel stack exposing the plurality of package edge conductors. An electrically-conductive material is deposited into the trenches and contacts the plurality of package edge conductors exposed therethrough. The panel stack is then separated into partially-completed stacked microelectronic packages. For at least one of the partially-completed stacked microelectronic packages, selected portions of the electrically-conductive material are removed to define a plurality of patterned sidewall conductors interconnecting the microelectronic devices included within the stacked microelectronic package.

A process for preparing a semiconductor structure for mounting to a carrier is disclosed. The process involves causing a support material to substantially fill a void defined by surfaces formed in the semiconductor structure and causing the support material to solidify sufficiently to support the semiconductor structure when mounted to the carrier.

A III-N device is described with a III-N material layer, an insulator layer on a surface of the III-N material layer, an etch stop layer on an opposite side of the insulator layer from the III-N material layer, and an electrode defining layer on an opposite side of the etch stop layer from the insulator layer. A recess is formed in the electrode defining layer. An electrode is formed in the recess. The insulator can have a precisely controlled thickness, particularly between the electrode and III-N material layer.

Methods for fabricating integrated circuits include fabricating a logic device on a substrate, forming an intermediate semiconductor substrate on a surface of the logic device, and fabricating a capacitor-less memory cell on the intermediate semiconductor substrate. Integrated circuits with capacitor-less memory cells formed on a surface of a logic device are also disclosed, as are multi-core microprocessors including such integrated circuits.

A microelectronic assembly and method of making, which includes a first microelectronic element (including a substrate with first and second opposing surfaces, a semiconductor device, and conductive pads at the first surface which are electrically coupled to the semiconductor device) and a second microelectronic element (including a handler with first and second opposing surfaces, a second semiconductor device, and conductive pads at the handler first surface which are electrically coupled to the second semiconductor device). The first and second microelectronic elements are integrated such that the second surfaces face each other. The first microelectronic element includes conductive elements each extending from one of its conductive pads, through the substrate to the second surface. The second microelectronic element includes conductive elements each extending between the handler first and second surfaces. The conductive elements of the first microelectronics element are electrically coupled to the conductive elements of the second microelectronics element.

When forming sophisticated semiconductor-based gate electrode structures of transistors, the pre-doping of one type of gate electrode structure may be accomplished after the actual patterning of the electrode material by using an appropriate mask or fill material for covering the active regions and using a lithography mask. In this manner, a high degree of flexibility is provided with respect to selecting an appropriate patterning regime, while at the same time a uniform and superior cross-sectional shape for any type of gate electrode structure is obtained.

The present invention provides an electroconductive sheet and a touch panel which do not impair visibility in a vicinity of an electrode terminal in a sensing region. In an electroconductive sheet which has an electrode pattern constructed of a metal thin wire and an electrode terminal that is electrically connected to an end of the electrode pattern, a transmittance of the electrode pattern is 83% or more, and when the transmittance of the electrode pattern is represented by a %, a transmittance of the electrode terminal is controlled to be (a-20)% or more and (a-3)% or less.

A liquid crystal display device includes a first substrate, a first electrode on the first substrate, a second substrate opposed to the first substrate, and a second electrode on the second substrate. The second electrode corresponds to the first electrode. The liquid crystal display device also includes a liquid crystal structure between the first electrode and the second electrode. The liquid crystal structure includes a plurality of liquid crystal molecules and at least one movement control member. The movement control member in the liquid crystal structure restricts a movement of the liquid crystal molecules.

The present invention provides a display device substrate, a display device substrate manufacturing method, a display device, a liquid crystal display device, a liquid crystal display device manufacturing method and an organic electroluminescent display device that allow suppressing faults derived from occurrence of gas and/or bubbles in a pixel region. The present invention is a display device substrate that comprises: a photosensitive resin film; and a pixel electrode, in this order, from a side of an insulating substrate. The display device substrate has a gas-barrier insulating film, at a layer higher than the photosensitive resin film, for preventing advance of a gas generated from the photosensitive resin film, or has a gas-barrier insulating film, between the photosensitive resin film and the pixel electrode, for preventing advance of gas generated from the photosensitive resin film.

The present invention relates to the development and manufacturing of viral vaccines. In particular, the invention relates to the field of industrial production of viral vectors and vaccines, more in particular to the use of avian embryonic stem cells, preferably the EBx® cell line derived from chicken embryonic stem cells, for the production of viral vectors and viruses. The invention is particularly useful for the industrial production of viral vaccines to prevent viral infection of humans and animals.

A multi-channel system and methods for sorting particles according to one or more characteristics of the particles. The system includes multiple flow cytometry units, each unit can have a nozzle for producing a fluid stream containing a desired population of particles in a mixture of particles. Each of the units may be operable to sort said desired population of particles by interrogating the fluid stream with a beam of electromagnetic radiation and classifying particles based on one or more characteristics of the particles. The system also includes a common fluid delivery system for delivering sheath fluid to each flow cytometer unit for producing respective fluid streams.

Disclosed are new members of a class of non-lipid small molecule inhibitors which interfere with the interaction between phosphoinositol-3,4,5-triphosphate (PIP3) and pleckstrin homology (PH) domains. These molecules target a broad range of PIP3-dependent signaling events in vitro and exert significant anti-tumor activity in vivo, with improved activity and selectivity toward particular PH domains. The small molecule inhibitors of the invention can be used alone or together with tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) or other cancer medicament to treat cancer. Small molecule inhibitors of the invention act synergistically in combination with TRAIL and with other Akt inhibitors in treating cancer. Pharmaceutical compositions and methods for treating cancer are provided.

The invention discloses novel morphology shifting micelles and amphiphilic coated metal nanofibers. Methods of using and making the same are also disclosed.

The invention is directed to a single-step method for rapidly and efficiently preparing protein-polymer conjugates, including an insulin-polymer conjugate. According to the method of the present invention, a protein and hydrophilic polymer are contacted in the presence of at least one organic solvent and at least one metal chelator, under conditions that promote the formation of a conjugate of the protein and polymer. Thus, the invention is directed to the site-specific modification of selected proteins, such as insulin, with poly(ethylene glycol) at residue PheB1. The invention also provides a pharmaceutical formulation for encapsulating the conjugate in a biodegradable polymer.

Monoclonal antibodies (mAbs) having thyroid stimulating activity (TSAb), especially full or considerably agonistic activity, or thyroid blocking activity (TBAb), which are obtainable by genetic immunization of mice, or fragments (F(ab')2, Fab or Fv) or humanized forms of such monoclonal antibodies or single chain forms (SCA; scFv) of such fragments, which antibodies, or their fragments, compete with bovine TSH for epitopes of the human TSHr, compete with autoantibodies from sera from Graves' patients as well as with autoantibodies from sera from patients harboring blocking autoantibodies for epitopes of the human TSHr, bind to conformational epitopes of the human TSHr located in the first 281 amino acids of the human TSHr, and usually also bind to TSFR receptors (TSHr) from different animals. Various uses of such antibodies, or of peptides corresponding to variable regions of such antibodies, are also described and claimed.

Devices and methods are provided for reducing matrix effects in protein precipitated bioanalytical samples comprising: a support, and a sorbent associated with the support capable of binding matrix interfering agents present in the bioanalytical sample, wherein the device further comprises filtering means for removing precipitated protein particles. The filtering means is a size exclusion filter or a polymeric or inorganic monolith having a maximum pore size less than or equal to the diameter of the particles to be removed from the sample, and can be integral with the sorbent or associated with the sorbent. The sorbent is characterized by sufficient selectivity between the matrix interfering agents and analytes of interest to provide retention of the matrix interfering agents while providing elution of the analytes of interest (e.g., a reversed phase or a polar modified reversed phase). Typical devices incorporating these features include luer syringe filters, individual filter cartridges, multiwell plates, pipette tips, or inline columns for multiple or single use.

The invention relates to methods and compositions for identifying and selecting maize plants with enhanced resistance to northern leaf blight. Maize plants generated by the methods of the invention are also a feature of the invention.