el [ASAP] A Chemical Switch for Transforming a Purine Agonist for Toll-like Receptor 7 to a Clinically Relevant Antagonist By feedproxy.google.com Published On :: Mon, 04 May 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c00011 Full Article
el [ASAP] Targeting ALK2: An Open Science Approach to Developing Therapeutics for the Treatment of Diffuse Intrinsic Pontine Glioma By feedproxy.google.com Published On :: Tue, 05 May 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c00395 Full Article
el [ASAP] Discovery of Potent, Selective, and Orally Bioavailable Inhibitors of USP7 with In Vivo Antitumor Activity By feedproxy.google.com Published On :: Wed, 06 May 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c00245 Full Article
el [ASAP] Selective Janus Kinase 2 (JAK2) Pseudokinase Ligands with a Diaminotriazole Core By feedproxy.google.com Published On :: Fri, 08 May 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c00192 Full Article
el [ASAP] Discovery of Selective, Covalent FGFR4 Inhibitors with Antitumor Activity in Models of Hepatocellular Carcinoma By feedproxy.google.com Published On :: Mon, 30 Mar 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.9b00601 Full Article
el [ASAP] Progress in the Field of Aldehyde Dehydrogenase Inhibitors: Novel Imidazo[1,2-<italic toggle="yes">a</italic>]pyridines against the 1A Family By feedproxy.google.com Published On :: Tue, 31 Mar 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.9b00686 Full Article
el [ASAP] Synthesis of Novel G Factor or Chloroquine-Artemisinin Hybrids and Conjugates with Potent Antiplasmodial Activity By feedproxy.google.com Published On :: Thu, 02 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.9b00669 Full Article
el [ASAP] Novel HIV-1 Protease Inhibitors with Morpholine as the P2 Ligand to Enhance Activity against DRV-Resistant Variants By feedproxy.google.com Published On :: Thu, 02 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00043 Full Article
el [ASAP] Substituted Naphthalenediimide Compounds Bind Selectively to Two Human Quadruplex Structures with Parallel Topology By feedproxy.google.com Published On :: Thu, 02 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00041 Full Article
el [ASAP] Characterization of an Alginate Encapsulated LS180 Spheroid Model for Anti-colorectal Cancer Compound Screening By feedproxy.google.com Published On :: Fri, 03 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00076 Full Article
el [ASAP] Structure Optimization of Gatastatin for the Development of ?-Tubulin-Specific Inhibitor By feedproxy.google.com Published On :: Mon, 06 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.9b00526 Full Article
el [ASAP] Chiral Analogues of PFI-1 as BET Inhibitors and Their Functional Role in Myeloid Malignancies By feedproxy.google.com Published On :: Tue, 07 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.9b00625 Full Article
el [ASAP] Discovery of BMS-986251: A Clinically Viable, Potent, and Selective ROR?t Inverse Agonist By feedproxy.google.com Published On :: Fri, 10 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00063 Full Article
el [ASAP] Novel Dithiolane-Based Ligands Combining Sigma and NMDA Receptor Interactions as Potential Neuroprotective Agents By feedproxy.google.com Published On :: Fri, 10 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00129 Full Article
el [ASAP] Selective Covalent Targeting of Mutated EGFR(T790M) with Chlorofluoroacetamide-Pyrimidines By feedproxy.google.com Published On :: Fri, 10 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.9b00574 Full Article
el [ASAP] Artemisinin Derivatives with Antimelanoma Activity Show Inhibitory Effect against Human DNA Topoisomerase 1 By feedproxy.google.com Published On :: Tue, 14 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00131 Full Article
el [ASAP] Discovery of an Atropisomeric PI3Kß Selective Inhibitor through Optimization of the Hinge Binding Motif By feedproxy.google.com Published On :: Wed, 15 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00095 Full Article
el [ASAP] Can Drug Repositioning Work as a Systematical Business Model? By feedproxy.google.com Published On :: Fri, 17 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00122 Full Article
el [ASAP] Discovery of CPI-1612: A Potent, Selective, and Orally Bioavailable EP300/CBP Histone Acetyltransferase Inhibitor By feedproxy.google.com Published On :: Mon, 27 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00155 Full Article
el [ASAP] Development of Selective Steroid Inhibitors for the Glucose-6-phosphate Dehydrogenase from <italic toggle="yes">Trypanosoma cruzi</italic> By feedproxy.google.com Published On :: Wed, 29 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00106 Full Article
el [ASAP] P2Y<sub>14</sub> Receptor Antagonists Reverse Chronic Neuropathic Pain in a Mouse Model By feedproxy.google.com Published On :: Thu, 30 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00115 Full Article
el [ASAP] Ultra-High-Throughput Acoustic Droplet Ejection-Open Port Interface-Mass Spectrometry for Parallel Medicinal Chemistry By feedproxy.google.com Published On :: Fri, 01 May 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00066 Full Article
el [ASAP] Discovery of Adamantane Carboxamides as Ebola Virus Cell Entry and Glycoprotein Inhibitors By feedproxy.google.com Published On :: Fri, 01 May 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00025 Full Article
el [ASAP] Benzoxazepine-Derived Selective, Orally Bioavailable Inhibitor of Human Acidic Mammalian Chitinase By feedproxy.google.com Published On :: Fri, 01 May 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00092 Full Article
el [ASAP] Development of a Raltegravir-based Photoaffinity-Labeled Probe for Human Immunodeficiency Virus-1 Integrase Capture By feedproxy.google.com Published On :: Tue, 05 May 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00009 Full Article
el [ASAP] Substituted Azabicyclo[2.2.1]heptanes as Selective Orexin-1 Antagonists: Discovery of JNJ-54717793 By feedproxy.google.com Published On :: Tue, 05 May 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00085 Full Article
el [ASAP] De-risking Drug Discovery of Intracellular Targeting Peptides: Screening Strategies to Eliminate False-Positive Hits By feedproxy.google.com Published On :: Tue, 05 May 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00022 Full Article
el [ASAP] Synthesis and Evaluation of <sup>11</sup>C- and <sup>18</sup>F-Labeled SOAT1 Inhibitors as Macrophage Foam Cell Imaging Agents By feedproxy.google.com Published On :: Wed, 06 May 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00127 Full Article
el Tanzania turns to solar power to increase electricity connectivity By latestsolarnews.com Published On :: Mon, 17 Apr 2017 22:05:48 +0000 As many as 60 percent of the Kenyan population now has access to electricity according to official data. But in neighbouring Tanzania, the penetration rate is less than half of that and sparsely populated rural communities are especially neglected. The post Tanzania turns to solar power to increase electricity connectivity appeared first on LatestSolarNews. Full Article News
el Spacing elements By simurai.com Published On :: Sun, 25 May 2014 00:00:00 +0000 So let’s say we have a “bar” with some items inside. Like a header or footer. Let’s also say we want those items to be spaced evenly, meaning they have the same gap everywhere. Shouldn’t be a big problem. Let’s take a look: 1. Margin We can’t just add margin: 2rem to the elements since there is no margin collapsing on the horizontal axis. And it also doesn’t work when using Flexbox. Leaving a double sized gap in between. Wishing there is something like margin: 2rem collapse; where you can enable/disable it optionally. See the Pen Spacing elements (no collapsing) by simurai (@simurai) on CodePen. 2. Pseudo classes Using margin: 2rem 0 2rem 2rem and then a pseudo class like :last-child { margin-right: 2rem } to add the extra margin works as long as you don’t need to hide that element with display: none. Maybe a rare case, but I’ve been running into this issue once in a while. Would be cool if there is something like :last-displayed that would ignore elements that have display:none. See the Pen Spacing elements (pseudo) by simurai (@simurai) on CodePen. 3. Margin + padding (best) The easiest way I think, is to add margins to all elements (like in the first example), but then also add the same value as padding to the parent element. Like this: .Header { padding: 1rem; } .Header-item { margin: 1rem; } That way all elements are evenly spaced and you still can use display:none without having to worry about breaking it. A little flaw is that you have to keep the 2 values in sync, but if you’re using a preprocessor, it can just be a single variable. Or maybe you could use REM’s to control it with font-size from the :root. See the Pen Spacing elements by simurai (@simurai) on CodePen. Other? There are more ways but I’m not aware of a simple one that also let’s you use display: none. Let me know otherwise. Maybe the Visual Format Language in GSS? Looks quite slick. Update A couple more options: Using Grandpa’s table, still need to test this Using calc() Using Adjacent selector More selector “hacks”: 1, 2 Hmmm.. gotta try some. I kinda like the 3rd one. Keeps it independent from the parent and is not “too” complicated. Full Article
el The matter of photography in the Americas / Natalia Brizuela and Jodi Roberts ; with contributions by Lisa Blackmore, Amy Sara Carroll, Marianela D'Aprile, María Fernanda Domínguez, Heloisa Espada, Rachel Price, Diana Ruiz, Tatiane Santa Ro By library.mit.edu Published On :: Sun, 16 Feb 2020 06:00:01 EST Rotch Library - TR184.B75 2018 Full Article
el Library of light: encounters with artists and designers / Jo Joelson By library.mit.edu Published On :: Sun, 16 Feb 2020 06:00:01 EST Rotch Library - N8219.L5 J64 2019 Full Article
el The women of Atelier 17: modernist printmaking in midcentury New York / Christina Weyl By library.mit.edu Published On :: Sun, 16 Feb 2020 06:00:01 EST Rotch Library - NE538.N5 W49 2019 Full Article
el The Pre-Raphaelites and science / John Holmes By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Hayden Library - NX454.5.P7 H65 2018 Full Article
el El nombre de un país / Mariana Telleria ; curadora, Florencia Battiti By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N6488.I8 V433 2019 A7 Full Article
el New design, neoplasticism: Nieuwe beelding / Piet Mondrian ; English translation by Harry Holtzman and Martin S. James By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N6948.5.D42 M6613 2019 Full Article
el The shrinking universe: Ireland at Venice 2019 / Eva Rothschild By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N6488.I8 V433 2019 I73 Full Article
el Gordon Parks: the new tide, early work, 1940-1950 / Philip Brookman ; with essays by Maurice Berger, Sarah Lewis, Richard J. Powell, Deborah Willis ; series editor, Peter W. Kunhardt, Jr By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - TR647.P37 2018 Full Article
el I have forgotten the night / Joël Andrianomearisoa ; curated by Rina Ralay Ranaivo and Emmanuel Daydé By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N6488.I8 V433 2019 M28 Full Article
el Fields of fungus and sunflowers / [edited and designed by Tammy Nguyen ; contributions by Lovely Umayam and Adriel Luis] By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N7433.35.U6 M37 no.6 Full Article
el Panos Charalambous, Eva Stefani, Zafos Xagoraris / curated by Katerina Tselou By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N6488.I8 V433 2019 G8 Full Article
el The shadow of dream cast upon Giardini della Biennale By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N6488.I8 V433 2019 U38 Full Article
el Albanian pavilion 2019: maybe the cosmos is not so extraordinary: Driant Zaneli By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N6488.I8 V433 2019 A38 Full Article
el Moon shine / Rachel Boillot By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - TR647.B626 2019 Full Article
el Performance now / RoseLee Goldberg By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - NX460.5.P47 G65 2018 Full Article
el The M.V.M. Cappellin glassworks and the young Carlo Scarpa: 1925-1931 / edited by Marino Barovier and Carla Sonego By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - NK5205.S28 A4 2018 Full Article
el Unfinished conversations on the weight of absence: Belu-Simion Făinaru, Dan Mihălțianu, Miklós Onucsán / curator, Cristian Nae By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N6488.I8 V433 2019 R6 Full Article
el Jakob Mohr / herausgegeben von Doris Noell-Rumpeltes + Thomas Röske By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - NC251.M64 J35 2018 Full Article
el Conversation pieces: the world of Bruegel / Abdelkader Benali, Alexandra van Dongen, Katrien Lichtert, Sabine Pénot, Lucinda Timmermans ; translation, Patrick Lennon, Michael Lomax By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - ND673.B73 B46 2018 Full Article
el Photography reframed: new visions in contemporary photographic culture / edited by Ben Burbridge and Annebella Pollen By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - TR185.P52 2018 Full Article