as

Nitrogen doped graphitic porous carbon from Almond Shell as an efficient persulfate activator for organic compounds degradation

New J. Chem., 2020, Accepted Manuscript
DOI: 10.1039/D0NJ01148G, Paper
Zakaria Anfar, Abdellah Ait El Fakir, Hassan Ait Ahsaine, Mohamed Zbair, Salaheddine Farsad, Fabrice Morlet-Savary, Amane Jada, Noureddine El Alem
Here, we have developed a simple and efficient low-temperature process for doping N into graphitic porous carbon to prepare a catalyst: N-GPC. Almond Shell (AS) as Bio-sourced material was used...
The content of this RSS Feed (c) The Royal Society of Chemistry




as

Discovery of [1,2,4]triazolo[4,3-a]pyrazine derivatives bearing 4-oxo-pyridazinone moiety as potential c-Met kinase inhibitors

New J. Chem., 2020, Accepted Manuscript
DOI: 10.1039/D0NJ00575D, Paper
Binliang Zhang, Xiaobo Liu, Hehua Xiong, Qian Zhang, Xin Sun, Zunhua Yang, Shan Xu, Pengwu Zheng, Wufu Zhu
Two series of [1,2,4]triazolo[4,3-a]pyrazine derivatives bearing 4-oxo-pyridazinone moiety (compounds 21a-l and 22a-l) were designed and evaluated for the IC50 values against three cancer cell lines (A549, MCF-7 and Hela) and...
The content of this RSS Feed (c) The Royal Society of Chemistry




as

Cd(II) coordination compounds as heterogeneous catalysts for microwave-assisted peroxidative oxidation of toluene and 1-phenyletanol

New J. Chem., 2020, Accepted Manuscript
DOI: 10.1039/D0NJ01408G, Paper
Manas Sutradhar, Tannistha Roy Barman, Elisabete Clara Bastos do Amaral Alegria, Hugo M Lapa, M. Fátima C. Guedes da Silva, Armando J. L. Pombeiro
The aroylhydrazone Schiff bases 2-hydroxy(2-hydroxybenzylidene)benzohydrazide (H2L1) and 2-amino(2-hydroxybenzylidene)benzohydrazide (H2L2) have been used to synthesize the new Cd(II) coordination polymer [Cd(-1ONO’:2O:3O’’-L1)(DMF)]n (1) and the dinuclear complex [Cd(1ONO’:2O-HL2)(OO’-Ac)]2·2DMF (2). Both 1 and...
The content of this RSS Feed (c) The Royal Society of Chemistry




as

Non-Photoisomerizable Butterfly Shaped Tetrasubstituted Azobenzenes: Synthesis and Photophysical Studies

New J. Chem., 2020, Accepted Manuscript
DOI: 10.1039/D0NJ01092H, Paper
Raman Arunachalam, Afeefah U Neelambra, Venugopal Karunakaran, Easwaramoorthi Shanmugam
The trans-azobenzene (AB) substituted derivatives with bulky carbazole (1), phenothiazine (2), and phenyl (3) have been synthesized to understand the effect of steric crowding around –N=N– linkage on the photoisomerization...
The content of this RSS Feed (c) The Royal Society of Chemistry




as

A nickel molybdenum oxide nanoarray as an efficient and stable electrocatalyst for overall water splitting

New J. Chem., 2020, Advance Article
DOI: 10.1039/D0NJ01232G, Paper
Xiaoshuang Zhang, Hui Su, Xiaoqiang Du
Experimental and DFT calculation results show that the presence of oxygen vacancies can decrease the adsorption energy of intermediates at active sites and facilitate their adsorption, thus improving the catalytic properties.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




as

The effect of vicinal di-halo substituents on the organogelling properties of aromatic supramolecular gelators and their application as soft templates

New J. Chem., 2020, Advance Article
DOI: 10.1039/D0NJ01440K, Paper
Andrea S. Mac Cormack, Verónica M. Busch, M. Laura Japas, Lisandro Giovanetti, Florencia Di Salvo, Pablo H. Di Chenna
Vicinal di-halo substituents have a determinant effect on the supramolecular self-assembly and properties of aromatic physical gelators with application as soft templates.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




as

Catalytic transfer hydrogenation of biomass-derived levulinic acid to γ-valerolactone over Sn/Al-SBA-15 catalysts

New J. Chem., 2020, Advance Article
DOI: 10.1039/D0NJ01288B, Paper
Sakthivel Kumaravel, Sivakumar Thiripuranthagan, Mani Durai, Elangovan Erusappan, Thanigaivel Vembuli
The synthesized inexpensive catalysts show high catalytic transfer hydrogenation activity at ambient N2 pressure under non-corrosive conditions. The Sn/Al-SBA-15 (25) catalyst exhibited the highest catalytic activity with 99% conversion of levulinic acid and 100% selectivity towards GVL.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




as

Narrow bandgap difluorobenzochalcogenadiazole-based polymers for high-performance organic thin-film transistors and polymer solar cells

New J. Chem., 2020, Advance Article
DOI: 10.1039/D0NJ01006E, Paper
Shengbin Shi, Qiaogan Liao, Hang Wang, Guomin Xiao
A series of difluorobenzochalcogenadiazole-bithiophene copolymers are developed for high-performance organic semiconductors.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




as

A cost-effective chitosan–oxine based thin film for a volatile acid vapour sensing application

New J. Chem., 2020, Advance Article
DOI: 10.1039/D0NJ01757D, Paper
M. M. Akhil Kumar, V. M. Biju
A polymer film based chemosensor was developed through the immobilization of chitosan and oxine, for the detection of TFA vapors.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




as

Water-soluble poly(N-isopropylacrylamide) nanoparticles grafted to trivalent lanthanide complexes as highly sensitive ratiometric nanothermometers

New J. Chem., 2020, Advance Article
DOI: 10.1039/D0NJ01263G, Paper
Josiane Aparecida Sobrinho, Gilmar Araújo Brito Júnior, Italo Odone Mazali, Fernando Aparecido Sigoli
A new water-soluble, luminescent ratiometric nanothermometer with a tunable temperature-responsive range, high thermal sensitivity and good repeatability was designed and synthesized by grafting lanthanide complexes to pNIPAM polymeric nanoparticles.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




as

Proton conduction in two Cu/Zn dimer-based hydrogen-bonded supramolecular frameworks from imidazole multi-carboxylate

New J. Chem., 2020, Advance Article
DOI: 10.1039/D0NJ01189D, Paper
Qingxu Wang, Zhejun Ye, Guoqing Shi, Kaimeng Guo, Gang Li
At 98% RH and 100 °C, two dimer-based HSFs show the best σ values of 3.13 × 10−4 S cm−1 for 1 and 0.55 × 10−4 S cm−1 for 2, which can be compared to the values of reported HSFs.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




as

Discrete and polymeric ensembles based on dinuclear molybdenum(VI) building blocks with adaptive carbohydrazide ligands: from the design to catalytic epoxidation

New J. Chem., 2020, Advance Article
DOI: 10.1039/D0NJ01045F, Paper
Edi Topić, Jana Pisk, Dominique Agustin, Martin Jendrlin, Danijela Cvijanović, Višnja Vrdoljak, Mirta Rubčić
Discrete and polymeric ensembles based on dimolybdenum(VI) units with adaptive carbohydrazide ligands are described. The polymeric complexes are efficient catalysts for cyclooctene epoxidation under eco-friendly conditions.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




as

A novel nanosensor for detecting tetracycline based on fluorescent palladium nanoclusters

New J. Chem., 2020, Accepted Manuscript
DOI: 10.1039/C9NJ06218A, Paper
Xiaoyan Du, Wenxia Dong, Zhongping Li, Guangming Wen, Meng Liu, Xiujun Fan
Tetracycline (TC) is considered one of the most widely used antibiotic medicines, which the global production and usage ranks the second highest in all antibiotics. In this work, palladium nanoclusters...
The content of this RSS Feed (c) The Royal Society of Chemistry




as

Facile functionalization of boron nitride (BN) for the development of high-performance asymmetric supercapacitors

New J. Chem., 2020, Advance Article
DOI: 10.1039/C9NJ06284J, Paper
Chandan Kumar Maity, Sumanta Sahoo, Kartikey Verma, Ajaya Kumar Behera, Ganesh Chandra Nayak
Ternary composites based on functionalized BN, a carbonaceous material, and PANI are developed for real-time asymmetric supercapacitor application.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




as

Synthesis of eight isostructural 2D lanthanide coordination polymers assembled by rigid furan-2,5-dicarboxylic acid and flexible adipic acid as linkers and exploration of luminescent Eu/Tb polymers as efficient and sensitive sensors for nitroaromatic comp

New J. Chem., 2020, Advance Article
DOI: 10.1039/D0NJ01018A, Paper
Zaib ul Nisa, Lobzang Tashi, Charanjeet Sen, Nargis Akhter Ashashi, Subash Chandra Sahoo, Haq Nawaz Sheikh
Eight isostructural coordination polymers were synthesized by a solvothermal method. The luminescent Eu/Tb polymers function as efficient sensors for nitroaromatics via turn-off mode.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




as

Iron and chromium MOFs as sustainable catalysts for transfer hydrogenation of carbonyl compounds and biomass conversions

New J. Chem., 2020, Advance Article
DOI: 10.1039/D0NJ00552E, Paper
Punitharaj Vasanthakumar, Dharmalingam Sindhuja, Duraisamy Senthil Raja, Chia-Her Lin, Ramasamy Karvembu
Fe and Cr based MOFs (MIL-88B) act as efficient and reusable catalysts for transfer hydrogenation of carbonyl compounds including bio-derived substrates.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




as

Synthesis and herbicidal application of turpentine derivative p-menthene type secondary amines as sustainable agrochemicals

New J. Chem., 2020, Advance Article
DOI: 10.1039/D0NJ00583E, Paper
Huanhuan Dong, Shichao Xu, Jing Wang, Hongmei Zhang, Yuxiang Chen, Liangwu Bi, Zhendong Zhao
Compound 3a showed excellent herbicidal activity against barnyard grass with IC50 = 7.0 mg L−1, and exhibited good selection for rice, wheat, and radish at 100 mg L−1.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




as

Ultrasound-assisted extraction of bioactive alkaloids from Phellodendri amurensis cortex using deep eutectic solvent aqueous solutions

New J. Chem., 2020, Advance Article
DOI: 10.1039/D0NJ00877J, Paper
Yuanbin Li, Zuchen Pan, Binshen Wang, Wen Yu, Siwei Song, Huanhuan Feng, Weiwei Zhao, Jiaheng Zhang
ChCl/citric acid-based DESs are demonstrated to be effective green solvents for the ultrasound-assisted extraction of bioactive alkaloids from herbs.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




as

Synthesis of a new Ni complex supported on CoFe2O4 and its application as an efficient and green catalyst for the synthesis of bis(pyrazolyl)methane and polyhydroquinoline derivatives

New J. Chem., 2020, Advance Article
DOI: 10.1039/D0NJ00223B, Paper
Taiebeh Tamoradi, Seyedeh Masoumeh Mousavi, Masoud Mohammadi
A novel and magnetic nanocatalyst was synthesized for the synthesis of multicomponent compounds.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




as

Ultrastable conductive microporous covalent triazine frameworks based on pyrene moieties provide high-performance CO2 uptake and supercapacitance

New J. Chem., 2020, Advance Article
DOI: 10.1039/D0NJ01292K, Paper
Mohamed Gamal Mohamed, Ahmed F. M. EL-Mahdy, Yasuno Takashi, Shiao-Wei Kuo
Two pyrene-functionalized CTFs through ionothermal treatment TCNPy in the presence of molten zinc chloride at 500 °C, which displayed high-performance CO2 uptake and supercapacitance.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




as

Fast and easy conversion of ortho amidoaryldiselenides into the corresponding Ebselen-like derivatives driven by theoretical investigations.

New J. Chem., 2020, Accepted Manuscript
DOI: 10.1039/D0NJ01605E, Paper
Vanessa Nascimento, Pâmella da Silva Cordeiro, Massimiliano Arca, Francesca Marini, Luca Sancineto, Antonio Luiz Braga, Vito Lippolis, Michio Iwaoka, Claudio Santi
DFT calculations performed on amidoaryldiselenides as electrophilic derivatives evidenced the presence of a prevalent Se···O weak interaction when selenium is bonded to a Se atom (diselenides), a Br atom (selenenyl...
The content of this RSS Feed (c) The Royal Society of Chemistry




as

Linear dicarboxylate based pyridyl appended cobalt(II) coordination polymers in search of opto-electronic properties

New J. Chem., 2020, Accepted Manuscript
DOI: 10.1039/D0NJ00567C, Paper
Faruk Ahmed, Joydeep Datta, Samim Khan, Basudeb Dutta, Sakhiul Islam, Sanobar Naaz, Partha Pratim Ray, Mohammad Hedayetullah Mir
Two new coordination polymers (CPs) [Co(adc)(4-ppy)(H2O)2]n, (1) and [Co(adc)(4-bppy)(H2O)2]n, (2) (H2adc = acetylenedicarboxylic acid, 4-ppy = 4-phenylpyridine and 4-bppy = 4-(4-bromophenyl)pyridine) have been synthesized and characterized by various techniques including...
The content of this RSS Feed (c) The Royal Society of Chemistry




as

A two-photon AIE fluorophore as a photosensitizer for highly efficient mitochondria-targeted photodynamic therapy

New J. Chem., 2020, Accepted Manuscript
DOI: 10.1039/D0NJ00822B, Paper
Qunshou Kong, Boxuan Ma, Tao Yu, Cheng Hu, Gaocan Li, Qing Jiang, Yunbing Wang
Nowadays, photodynamic therapy (PDT) has become an effective way for cancer therapy. However, there are still some drawbacks for common photosensitizers including poor photostability, nonspecific targeting, poor penetration depth of...
The content of this RSS Feed (c) The Royal Society of Chemistry




as

The classification and application of cyclodextrin polymers: a review

New J. Chem., 2020, Accepted Manuscript
DOI: 10.1039/C9NJ05844C, Perspective
Bingren Tian, Jiayue Liu
The designing and constructing of polymer structures play an important role in the field of polymer science. In addition, polymers can provide good ideas and opportunities for the development of...
The content of this RSS Feed (c) The Royal Society of Chemistry




as

Novel phthalocyanine-based micelles/PNIPAM composite hydrogels: spatial/temporal-controlled drug release triggered by NIR laser irradiation

New J. Chem., 2020, Accepted Manuscript
DOI: 10.1039/D0NJ01882A, Letter
Tao Jia, Lu Li, Enna Ha, Zheng Qu, Lei Shi, Tiedong Sun, Shengnan Tan, Wancheng Zhao
Near-infrared (NIR) light-responsive hydrogels hold significant potential for biomedical application, especially in remote-controlled release of anticancer drugs. Herein we report a novel NIR light responsive composite hydrogel system that undergoes...
The content of this RSS Feed (c) The Royal Society of Chemistry




as

Cobalt-based Layered Double Hydroxides Revisited: evidence for an oxidizing radical generation

New J. Chem., 2020, Accepted Manuscript
DOI: 10.1039/D0NJ00380H, Paper
Rafael dos Santos Macedo, Rodrigo Boni Fazzi, Ana Maria Da Costa Ferreira, Vera R._Leopoldo Constantino
Layered double hydroxides (LDHs) containing transition metal elements such as cobalt have been studied mainly for applications in electrochemical devices and as catalysts. Fundamental studies about Co-based LDHs are required...
The content of this RSS Feed (c) The Royal Society of Chemistry




as

Efficient modulation of upconversion luminescence in NaErF4-based core-shell nanocrystals

New J. Chem., 2020, Accepted Manuscript
DOI: 10.1039/C9NJ06240H, Letter
Tingting Pan, Li-Yuan Sun, Rongyao Gao, Li-Min Fu, Xi-Cheng Ai, Jian-Ping Zhang
Efficient modulation of upconversion selectivity of heavily-doped core-shell nanocrystals was achieved through precisely tuning of [F]/[RE] ratio during the synthesis. Brighter upconversion luminescence with smaller nanoparticle size and tunable color...
The content of this RSS Feed (c) The Royal Society of Chemistry




as

Whole Genome Sequence Analysis and Homology Modelling of Main Protease and Non-Structural Protein 3 of the SARS-CoV-2 reveals an Aza-Peptide and a Lead Inhibitor with Possible Antiviral Properties

New J. Chem., 2020, Accepted Manuscript
DOI: 10.1039/D0NJ00974A, Paper
Arun K Shankar, Divya Bhanu, Anjani Alluri, Samriddhi Gupta
The family of viruses belonging to Coronaviridae consist of virulent pathogens that have a zoonotic property, Severe Acute Respiratory Syndrome (SARS-CoV) and Middle East Respiratory Syndrome (MERS-CoV) of this family...
The content of this RSS Feed (c) The Royal Society of Chemistry




as

A non-enzymatic electrochemical approach for L-Lactic acid sensor development based on CuO.MWCNT nanocomposites modified with a nafion matrix

New J. Chem., 2020, Accepted Manuscript
DOI: 10.1039/D0NJ01715A, Paper
Mohammad M. Hussain, Abdullah M. Asiri, Mohammed M. Rahman
Copper oxide ornamented multi-walled carbon nanotube nanocomposites (CuO.MWCNT NCs) were prepared using an unsophisticated wet-chemical technique in basic medium. CuO.MWCNT NCs was examined by using various analytical techniques for example...
The content of this RSS Feed (c) The Royal Society of Chemistry




as

Construction and application of nonenzymatic ascorbic acid sensor based on NiO1.0/polyaniline3.0 hybrid

New J. Chem., 2020, Accepted Manuscript
DOI: 10.1039/D0NJ00696C, Paper
shichao Zhu, Aijuan Xie, Bingyan Wei, Xiang Tao, Jianghui Zhang, Wenhao Peng, Chenyang Liu, Linyang Gu, Chenfei Xu, Shiping Luo
NiO1.0/PANI3.0 was prepared by in-situ polymerization method in one-pot and applied in detection of ascorbic acid (AA). Cyclic voltammetry (CV) and Differential pulse voltammetry (DPV) were used to optimize the...
The content of this RSS Feed (c) The Royal Society of Chemistry




as

Facile assemble of 2D α-zirconium phosphate supported silver nanoparticles: superior and recyclable catalysis

New J. Chem., 2020, Accepted Manuscript
DOI: 10.1039/D0NJ01378A, Paper
Yonghang Xu, Fangya Zhou, Min Chen, Huawen Hu, Limiao Lin, Jingshu Wu, Min Zhang
A novel, efficient and durable ZrP@PDA/Ag nanocatalyst was prepared via facile reduction and deposition of silver nanoparticles (AgNPs) on two dimensional (2D) α-zirconium phosphate (ZrP) nanosheets using bio-inspired dopamine chemistry....
The content of this RSS Feed (c) The Royal Society of Chemistry




as

POM-based dyes featured rigidified bithiophene π linkers: Potential high-efficient dyes for dye-sensitized solar cells

New J. Chem., 2020, Accepted Manuscript
DOI: 10.1039/D0NJ01150A, Paper
Yu Gao, Li-Kai Yan, Wei Guan, Yanhong Xu
A series of POM-based dyes with triphenylamine electron donor group, cyanoacrylic acid electron acceptor group and different π linkers of thiophene derivatives are systematically investigated to analyze the influence of...
The content of this RSS Feed (c) The Royal Society of Chemistry




as

Cu(II)Cl2 Containing Bispyridine-based Porous Organic Polymer Support Prepared via Alkyne-Azide Cycloaddition as a Heterogeneous Catalyst for Oxidation of Various Olefins

New J. Chem., 2020, Accepted Manuscript
DOI: 10.1039/D0NJ01174F, Letter
Jong Ho Yoon, Hye Min Choi, Suk Joong Lee
New class of porous organic polymer (POP) based heterogeneous catalyst Cu-POP was prepared from immobilizing Cu(II)Cl2 into bpy containing POP prepared via alkyne-azide cycloaddition. This new catalyst showed efficient catalytic...
The content of this RSS Feed (c) The Royal Society of Chemistry




as

The Breakfast of Champions

Previewing the November/December issue of B&C.




as

Podcast: Coming Attractions for 2014, Part 1

George Marsden on “The Twilight of the American Enlightenment.”




as

Love & Treasure

Ayelet Waldman’s powerful new novel.




as

The Tallgrass Prairie Reader

Glimpses of a lost world.




as

Roz Chast’s World

Two books from the great cartoonist.




as

The Novel as Protestant Art

Previewing the March/April issue of Books & Culture.




as

[ASAP] Structural and Biological Basis of Small Molecule Inhibition of <italic toggle="yes">Escherichia coli</italic> LpxD Acyltransferase Essential for Lipopolysaccharide Biosynthesis

ACS Infectious Diseases
DOI: 10.1021/acsinfecdis.9b00127




as

[ASAP] Pyrimidine Analogues as a New Class of Gram-Positive Antibiotics, Mainly Targeting Thymineless-Death Related Proteins

ACS Infectious Diseases
DOI: 10.1021/acsinfecdis.9b00305




as

[ASAP] Potentiation of Antibiotics against Gram-Negative Bacteria by Polymyxin B Analogue SPR741 from Unique Perturbation of the Outer Membrane

ACS Infectious Diseases
DOI: 10.1021/acsinfecdis.9b00159




as

[ASAP] Substrate Tolerance of Bacterial Glycosyltransferase MurG: Novel Fluorescence-Based Assays

ACS Infectious Diseases
DOI: 10.1021/acsinfecdis.9b00242




as

[ASAP] Broad Spectrum ß-Lactamase Inhibition by a Thioether Substituted Bicyclic Boronate

ACS Infectious Diseases
DOI: 10.1021/acsinfecdis.9b00330




as

[ASAP] Antibacterial Photodynamic Inactivation of Antibiotic-Resistant Bacteria and Biofilms with Nanomolar Photosensitizer Concentrations

ACS Infectious Diseases
DOI: 10.1021/acsinfecdis.9b00379




as

[ASAP] Multitarget Approaches against Multiresistant Superbugs

ACS Infectious Diseases
DOI: 10.1021/acsinfecdis.0c00001




as

[ASAP] Advancement of GyrB Inhibitors for Treatment of Infections Caused by <italic toggle="yes">Mycobacterium tuberculosis</italic> and Non-tuberculous Mycobacteria

ACS Infectious Diseases
DOI: 10.1021/acsinfecdis.0c00025




as

[ASAP] Broadening Activity of Polymyxin by Quaternary Ammonium Grafting

ACS Infectious Diseases
DOI: 10.1021/acsinfecdis.0c00037




as

[ASAP] Small Molecule Carboxylates Inhibit Metallo-ß-lactamases and Resensitize Carbapenem-Resistant Bacteria to Meropenem

ACS Infectious Diseases
DOI: 10.1021/acsinfecdis.9b00459




as

[ASAP] Target-Based Design of Promysalin Analogues Identifies a New Putative Binding Cleft in Succinate Dehydrogenase

ACS Infectious Diseases
DOI: 10.1021/acsinfecdis.0c00024