A handheld electronic device includes a reduced QWERTY keyboard and is enabled with a disambiguation routine that is operable to disambiguate text input. In addition to identifying and outputting representations of language objects that are stored in the memory and that correspond with a text input, the device is able to perform a spell check routine during input of a text entry and to learn and automatically correct mistakes typically made by the particular user.

A system for translating user motion into multiple object responses of an on-screen object based on user interaction of an application executing on a computing device is provided. User motion data is received from a capture device from one or more users. The user motion data corresponds to user interaction with an on-screen object presented in the application. The on-screen object corresponds to an object other than an on-screen representation of a user that is displayed by the computing device. The user motion data is automatically translated into multiple object responses of the on-screen object. The multiple object responses of the on-screen object are simultaneously displayed to the users.

A user interface (UI) is presented in which a UI client engine is associated with an application, and a UI rendering engine is associated with the client engine. The UI rendering engine receives the scene graph and data items associated with elements of the scene graph, and processes a rendering thread to render a UI in accordance with the scene graph and the data items, independently of further input from the client UI engine.

A system and method for implementing a dynamic menu characterized by a real-time menu architecture. An example method includes determining a menu structure, with reference to a data set, for use with user interface software. A menu is then displayed, wherein the menu includes menu items arranged according to the menu structure. An initial drop-down menu list of the menu includes one or more of the menu items. Each menu item is associated with a data object of the data set. A signal is generated when a change is made to a data set corresponding to a menu item. The menu is then updated based on the signal. In an illustrative embodiment, the example method further includes employing a browser to trigger implementation of the method. The browser communicates with a web server, which communicates with an application that is adapted to analyze the data set and associated data structure and provide an update in response thereto via, the signal, to the web server. The web server includes software for enabling the browser to render an updated menu or graphical representation thereof.

Architectures and techniques are provided to control the rendering of supplemental content associated with electronic books. For example, electronic books may be associated with content that is in addition to the content originally provided to an individual acquiring the electronic book, such as annotations, social networking site information, media outlet information, and the like. Individuals may control the supplemental electronic book content that is rendered via their client devices via actuation of a physical input device or a representation of an input device shown via a touch sensitive display. The amount of supplemental content that is rendered may correspond to information associated with a specified number of categories of supplemental electronic book content based on a supplemental content rendering level. In other implementations, the amount of supplemental electronic book content that is rendered may correspond to an amount of supplemental content to be rendered for each category of supplemental content.

Images are analyzed within a 3D environment that is generated based on spatial relationships of the images and that allows users to experience the images in the 3D environment. Image analysis may include ranking images based on user viewing information, such as the number of users who have viewed an image and how long an image was viewed. Image analysis may further include analyzing the spatial density of images within a 3D environment to determine points of user interest.

The present invention relates to I- and II-type crystals of L-α-glyceryl phosphoryl choline, and to a method for preparing same. More particularly, the present invention relates to noble I- and II-type anhydride crystals of L-α-glyceryl phosphoryl choline, which have a higher purity than conventional liquid L-α-glyceryl phosphoryl choline, and one advantage of which is that formulations and dosages of pharmaceuticals are easily modified, and another advantage of which is that the hygroscopicity of the crystals are much lower than that of conventional polymorphic crystals, providing excellent stability during storage. The present invention also relates to a method for preparing the I- and II-type crystals of L-α-glyceryl phosphoryl choline. The I-type crystal of L-α-glyceryl phosphoryl choline is characterized by having an onset temperature of 147° C. and an absorption peak of 150° C. based on differential scanning calorimeter (DSC) analysis, and by having diffraction patterns where 2θ-diffraction angles are 9.8±0.2°, 12.0±0.2°, 14.3±0.2°, 15.8±0.2°, and 19.6±0.2° based on X-ray diffraction (XRD) analysis. The II-type crystal of L-α-glyceryl phosphoryl choline is characterized by having an onset temperature of 62° C. and an absorption peak of 66° C., and an onset temperature of 141° C. and an absorption peak of 145° C. based on DSC analysis, and having diffraction patterns where 2θ-diffraction angles are 10.3±0.2°, 12.2±0.2°, 13.4±0.2°, 14.8±0.2°, and 20.6±0.2° based on XRD analysis.

The present invention relates to novel isocyanate and isothiocyanate compounds, to pharmaceutical compositions comprising them, and to the use thereof in the treatment of cancer diseases in humans and animals. The novel isocyanate and isothiocyanate compounds are distinguished, as compared with the known isocyanate and isothiocyanate compounds, by improved therapeutical breadth, i.e. fewer side effects while having high anti-tumor activity.

Provided is an efficient technology for synthesizing diamino acids (diamino acid derivatives). Disclosed is a manufacturing method for diamino acid derivatives wherein the fluorenyl groups of the diamino acid derivative starting materials represented by General Formula [II] or [IV] are removed.

Novel oxidized thiophospholipids are provided herein, as well as methods for producing same, and uses thereof in treating or preventing an inflammation associated with endogenous oxidized lipids and related conditions. Exemplary oxidized thiophospholipid according to embodiments described herein have the formula: wherein X1, X2, A1, A2, B', B″, D' and D″ are as described herein.

This invention relates to novel precursors suitable for 18F radiolabeling of glutamate derivatives, methods for preparing such compounds and its intermediates, compositions comprising such compounds, kits comprising such compounds or compositions and methods for 18F radiolabeling of glutamate derivatives wherein the obtained 18F radiolabeled glutamate derivatives are suitable for diagnostic imaging by Positron Emission Tomography (PET) of proliferative diseases e.g. tumor in mammals.

A phosphazene compound having a vinyl group is manufactured by a reaction between a vinyl compound and a phosphazene compound having a hydroxyl group and added to a resin composition for manufacturing a prepreg or a resin film so as to be applicable to copper-clad laminates and printed circuit boards to thereby achieve satisfactory circuit laminate properties, namely low coefficient of thermal expansion, low dielectric properties, heat resistant, fire resistant, and halogen-free.

Fluoroalkyl alkyl carbonates and fluorosubstituted carbamates which are suitable as additives or solvents in lithium ion batteries are prepared from fluoroalkyl fluoroformates and the respective alcohol or amine. Methanol is the preferred alcohol, dimethylamine and diethylamine are preferred amines. Fluoromethyl methyl carbonate is the preferred compound to be produced. Fluoroalkyl fluoroformates can be prepared from aldehydes and carbonyl fluoride.

The present invention relates to a process for the synthesis of 2-cyanophenylboronic acid and the esters and salts thereof of formula (II), which are intermediates of the synthesis of active pharmaceutical ingredients such as Perampanel or E2040. formula (II): (II).

The present invention provides a process for preparing triorgano borates with low alcohol content.

The present disclosure relates to a sulfonated benzene compound emitting fluorescence by reaction with hydrogen peroxide, aqueous-dispersed fluorescent nanoprobes applicable for real-time detection of hydrogen peroxide, and a fluorescent nanoprobe fabrication method. The fluorescent nanoprobe contains the following sulfonated benzene compound and water.

A novel substituted N-acetyl-L-cysteine (NAC) derivative and methods of using this compound for the treatment of diseases and/or conditions, including but not limited to diseases and/or conditions of, or involving, the Central Nervous System (CNS), including schizophrenia adrenoleukodystrophy, mitochondrial diseases (e.g. Leigh syndrome, Alpers' disease, and MELAS), Huntington's disease, trichotillomania, HIV-associated neurocognitive disorder, hypoxic-ischemic encephalopathy, drug craving, and drug addiction.

Substituted phenylcarbamoyl alkylamino arenes; substituted phenylthiocarbamyl alkylamino arenes; substituted phenylcarbamoyl alkylamino heteroarenes; substituted phenylthiocarbamyl alkylamino heteroarenes; N-substituted aryl, N'-substituted aryl urea compounds; N-substituted aryl, N'-substituted heteroaryl urea compounds; N-substituted aryl, N'-substituted aryl thiourea compounds and N-substituted aryl, N'-substituted heteroaryl thiourea compounds are provided and may find use as androgen receptor modulators. The compounds may find particular use in treating prostate cancer, including castration-resistant prostate cancer and/or hormone-sensitive prostate cancer.

Alkyl nitrate ester compounds are provided for the delivery of nitric oxide to targeted muscle tissues, and in particular, to normal and dystrophic muscles. In one aspect, nitrate ester compounds are provided having the following formula: wherein, R1 is ONO2, CH2ONO2, CnH2n+1OH, CnH2n+1OH, or CH2CH2CH3, or H;R2 is ONO2, CH2ONO2, Cn'H2n'+1OH, Cn'H2n'+1OH, CH2CH2CH3 or H; andR3 is ONO2, CH2ONO2, Cn'″H2n″+1OH, Cn″H2n″+1OH, CH2CH2CH3 or H; wherein n is an integer from 0 to 9, n' is an integer from 0 to 9, and n″ is an integer from 0 to 9, and n+n'+n″≦9, and wherein at least one of R1, R2, and R3 is an ester nitrate selected from the group consisting of ONO2, CH2ONO2, and combinations thereof.

The esterfication of hypophosphorous acid is followed by reaction with another molecule of alcohol under the action of a nickel catalyst to provide a green method for the preparation of H-phosphonate diesters. This method avoids the need for any stoichiometric chlorine unlike those based on phosphorous trichloride.

Preparation method of aromatic boronate compound is provided, in which the is as follows: reacting aromatic amine Ar-NH2, with diboronic ester and alkyl nitrite in the presence of organic solvent, where Ar represents non-heterocyclic aryl. It enables for the first time the preparation of aromatic boronate from aromatic amine in one step by the present method.

Aromatic N-halosulfonamide organic compounds have been known for over one hundred years. The ability of these compounds to release active halogen ions has been utilized in a range of biocidal and fungicidal applications. This disclosure deals with the use of halo active aromatic sulfonamide organic compounds as odor control and/or biocidal agents in a cleaning solution for use with bovines and other dairy animals.

The invention provides a process for preparing diaryl carbonates from dialkyl carbonates and aromatic hydroxyl compounds using at least two reaction columns, a process section for recovering the dialkyl carbonate used in the reaction and for removing the alcohol of reaction, one or more process steps for removing the by-products obtained in the process which have a boiling point between that of the dialkyl carbonate and that of the alkyl aryl carbonate formed during the preparation of the diaryl carbonate, and a process step for further purification of the diaryl carbonate obtained from the reaction columns.

A system receives a first request for data associated with a data stream received over a first network from a remote source and then determines when the requested data will be available based on analyzing the data stream. The system communicates a second request for the requested data over a second network to the remote source when the requested data will not be available from the data stream within a threshold time and receives the requested data from the remote source over at least one from the list including the first network and the second network.

There is provided a system and method for dynamically generated client side streaming playlists. There is provided a method comprising receiving a request to stream a video asset for playback, retrieving, from a network, a video asset playlist corresponding to the video asset and an ad campaign playlist, generating a consolidated video playlist including the video asset playlist and the ad campaign playlist, and processing the consolidated video playlist using a media playback framework to stream a plurality of video files from the network for decoding and output to a display. Discontinuity tags within the video asset playlist may be utilized as insertion points for portions of the ad campaign playlist. The consolidated video playlist may be accessed through a local HTTP web server, advantageously allowing the use of commonly installed media playback framework models such as QuickTime X to trigger adaptive bitrate support through HTTP Live Streaming.

Internet streaming from broadcast radio or television stations is described wherein triggers for dynamic content from internal or external systems cause an encoder system to generate command messages, and to optionally synchronize those command messages with any delays associated with the triggering events. Command messages are delivered through a streaming media distribution system to client media players which obtain or present the dynamic content, in association with any desired configuration changes to the appearance of the media player or the method or manner in which the dynamic content is presented.

A system, method, and computer-readable medium are disclosed for realizing server management functionalities in the absence of a routable Internet Protocol (IP) network address of a remote access controller (RAC). A first device, which is operatively coupled to a link-local network, generates a Multicast Domain Name System (mDNS) IP multicast query message, which it then sends to a second device on the link-local network. In response, the second device, which comprises a RAC, returns its link-local IP address to the first device.

Described herein are systems and methods for enabling a collaborative remote desktop environment. The system includes a computing device and a first application instance that has an application state associated therewith. The first application instance includes, or is associated with, a current state component and application data/data files. The system further includes an application launcher that is used to instantiate a second application instance operating either on the same or on a different computing device. The second application instance similarly has an application state associated therewith and is associated with the application launcher. Upon receiving a request from the second user to interact with the first application instance, the application state and the application data/data files are communicated to the application launcher, and the application launcher instantiates the second application instance so that its state is substantially identical to that of the first application instance.

A printing device includes a printing device side wireless communication unit configured to execute wireless communication with a mobile terminal, an operation acquisition unit configured to acquire user operation thereof, and a processor. The processor is configured to acquire operation data which is generated as the operation acquisition unit acquires a user operation, acquire establishment data which is generated as the printing device side wireless communication unit establishes a wireless communication with the mobile terminal, and issue a request control to control the printing device side wireless communication unit to transmit request data requesting the mobile terminal to transmit print data necessary for printing, via the wireless communication, when the establishment data is acquired, the request control being issued in accordance with the operation data as acquired.

Various system and method embodiments are disclosed that include using a first node to receive messages including error information from a plurality of client computers via a computer network. Recommendations for resolving errors associated with the error information are made available to the client computers via the computer network.

A method, system and computer program product are disclosed for user initiated rule based restrictions on sending messages from a sender to a receiver in a communications network. The receiver establishes a set of rules for the sender that allows the sender a limited number of defined messages events with the receiver. The defined message events may be messages or message sessions. When the sender attempts to send a message to the receiver, it is determined whether a message session currently exists between the sender and the receiver. If a current session exists, the rules set by the receiver are used to determine if the message is allowed to be sent to the receiver. If a session does not currently exist, the rules are used to determine whether a new session is allowed. If a new message session is allowed, a new session is established, and the message is sent to the receiver during the new session.

A CPU executes a communication partner search process for searching for a communication partner (another game machine). The CPU confirms received data content. If identification information included in the received data matches, application identification information saved in a wireless communication module is compared with application identification information included in the received data. When the pieces of application identification information match, a notice that another game machine having exchange data corresponding to the matched application identification information is found is given to a main body. Then, giving/receiving of exchange data is executed to/from another game machine.

A risk aware domain name service (DNS), which includes modulating a time to live (TTL) value associated with the DNS based at least in part on one or more DNS-related metrics associated with a DNS server providing DNS resolution is disclosed. A zone file that indicates a particular TTL value may be generated based at least in part on the one or more DNS-related metrics and provided to the DNS server.

A method of transferring data using a Trivial File Transport Protocol (TFTP) includes sending first request packet from client to server, first request packet requesting that first file be transferred; transferring first file according to first request packet if first acknowledgement packet is received at client from server indicating that server can accommodate request of first request packet; sending second request packet from client to the server if transfer of first file does not complete successfully, the second request packet including TFTP option indicating that transfer of first file be retried beginning at first block after final block that was successfully transferred in response to first request packet; and retrying transfer of first file according to second request packet if second acknowledgement packet is received at client from server indicating that server can accommodate request of second request packet.

In order to allow a single user registered on a single local host or other machine to access multiple shared resources on a remote host, an aliasing mechanism is employed so that multiple concurrent connections can be established by the user to a single remote host, with each connection using a different identity. Each connection can therefore be used to access a different shared resource on the remote host. In some illustrative examples, a user's identifier such as his or her machine log-in identification may be associated with two or more resource sharing aliases. As a result, two or more resource sharing sessions can be established by the user with a single remote host, with each of the sessions using a different one of the aliases. The resource sharing sessions are usually established in accordance with a resource sharing protocol such as the Server Block Message (SBM) protocol.

Various arrangements for creating and using generic universal resource indicators are presented. To create a generic universal resource indicator, one or more parameters of a universal resource indicator may be identified. An interface that permits a parameter of the one or more parameters to be selected and mapped to a variable may be presented. A selection of the parameter for mapping may be received. An indication of the variable to map to the parameter of the selection may also be received. The generic universal resource indicator having a generic parameter corresponding to the parameter of the selection may be created.

An apparatus and method control a connection between peripheral devices in a control server of a wireless communication system providing an IP-based communication service. The method for controlling the connection between peripheral devices includes registering at least one device in a group list classified by user identification information. The method also includes, if a control node including a user identifier of the group list requests a control of any one device included in the group list, checking an IP address of the device that is requested to be controlled by the control node. The method further includes sending a control command of the control node using the IP address.

An example method to monitor media exposure involves receiving, at a first internet domain, a first request from a client computer, the first request indicative of access to the media at the client computer. The example method also involves determining if the client computer is known. If the client computer is not known, a response is sent from the first internet domain to the client computer, the response to instruct the client computer to send a second request to a second internet domain, the second request to be indicative of access to the media at the client computer. If the client computer is known, an impression of the media is logged.

A method for depositing a wear-resistant decorative coating on a substrate, comprising a first stage of vacuum deposition on the surface of the substrate of a layer of at least one metal of the group titanium, zirconium, hafnium, vanadium, niobium, tantalum, chromium, molybedenum, tungsten and aluminium, to which is added at least one element of the group carbon, nitrogen, oxygen, boron, silicon, fluorine, chlorine, sulfur and phosphorus; a second stage including activation of the first layer by ionic bombardment under vacuum conditions and simultaneous deposition of a second fine layer of a metal or metal alloy; and a third stage involving galvanic deposition of a third layer of a decorative metal coating over the second layer.

The watch case of this invention includes a caseband (2) made from sintered material and a back cover (10) secured to the caseband by means of at least two pins (12). Each pin passes through a first hole (14) provided in a first projection (16) formed in the caseband and two second holes (13, 15) provided respectively in two second projections (17, 18) formed in the back cover, said second projections being arranged respectively on either side of said first projection. Each pin being axially retained in its holes by the elastic effect provided by the seal when the caseband lies on the back cover.

When a speech sound of at least a predetermined sound pressure is externally input while a time measurement is not being performed, a time measuring circuit starts a time measurement responsive to a signal from a speech detector. When another speech sound of at least a predetermined sound pressure is externally input while a time measurement is being performed by the time measuring circuit, a measurement time measured by the time measuring circuit at this moment is stored in a time information memory. After a predetermined time has elapsed, if a speech recognition circuit recognizes that the externally input speech sound is a "stop" command, the time measurement operation performed by the time measuring circuit is stopped, and the time information stored in the time information memory is read out and displayed as measurement time information on a display unit.

In an apparatus for recording and quickly retrieving video signal parts on a magnetic tape, during recording information about the local position of each video signal part is automatically stored in a memory associated with the apparatus, which is designed for storing identifying information for a large number of magnetic tape cassettes. The retrieval of each video signal part on each of the cassettes can be effected substantially without delay in the quick rewind mode of operation.

The disclosed device enables the recording of television broadcasts which are preprogrammed in a memory. The presence of data lines of the television signal in combination with the presence of a color television signal is checked. When the data lines stop, the video recorder is switched on in real time by a clock time signal.

A device and method provide for an accurate output from a unit, such as an oscillator and/or clock providing an output indicative of frequency and/or time. The device includes a processing section having a microprocessor that develops a model characterizing the performance of the device, including establishing predicted accuracy variations, and the model is then used to correct the unit output. An external reference is used to provide a reference input for updating the model, including updating of predicted variations of the unit, by comparison of the reference input with the unit output. The ability of the model to accurately predict the performance of the unit improves as additional updates are carried out, and this allows the interval between the updates to be lengthened and/or the overall accuracy of the device to be improved. The accuracy of the output is thus adaptively optimized in the presence of systematic and random variations.

A wind direction indicating and time display unit is provided for use at the tee areas of a golf course. The unit wind direction indicating device is mounted on an upper surface of a support structure and extends upwardly therefrom. The wind direction indicating device includes a support pole, a sleeve mounted for rotation on the pole at the top thereof, a wind direction indicating element, such as a flag, secured to the sleeve and movable in response to changes in wind direction, and a pole support fitting. Secured to the upper surface of the support structure. A time display device, such as a clock, is secured in a laterally facing wall surface of the support structure.

A time-locked cigarette case has time-controlled locking mechanism which is manually adjustable by the user and also has a first latch rod which normally retains the case in a closed condition and a second latch rod which moves to retain the case in a closed condition if the first latch rod is jolted to an open position so as to prevent the case from being opened by jolting before the manually set time delay has expired.

A radio paging selective receiver determines that a received message is unread based on the time difference between the message reception time and the current time being larger that some predetermined value of time, and the paging selective receiver provides an indication of the unread message by displaying the reception time of the unread message in a second fashion which is visibly different from a first fashion normally used to display the current time.

An equatorial sundial apparatus with an adjustable base assembly utilizing one or more concave cylindrical focusing mirrors. One of the benefits that is derived from this apparatus is the use of one or more concave cylindrical mirrors to project a focused beam of light onto a calibrated surface from which the time can be read. This sundial has the additional benefit of not suffering from blurring of the time indicator in a shadow or non-focused beam of light typical of other sundials. This sundial's focused light forms a sharply demarcated indicator from which time can be read to the minute. A further benefit of this apparatus is the ability to incorporate multiple concave cylindrical focusing mirrors to reduce the size of the visual field or screen where the time is read and to incorporate various shapes and designs for ornamental purposes without significant compromise of the sundials accuracy for telling time. An additional benefit of this apparatus is the ability to quickly, accurately and easily adjust the apparatus to the proper tilt upon setup according to the latitude where it will be located by means of an adjustable base assembly.

A first circuit having a first coil electrically charges a second circuit having a second coil through electromagnetic coupling of the two coils. When data signals are to be transferred between the first and second circuits, signal transfer is started only after the second circuit has been charged for a predetermined period of time. The position relationship between the coils is also detected, and a charging/transfer selector changes a duty ratio between charge transfer and data transfer in accordance with the detected result. The charge is transferred in an intermittent manner, and the charging rate is adjusted according to the difference between the voltage of a secondary battery observed during a charging phase and the voltage of the secondary battery observed a certain time after interruption of the charging phase, or vice versa.

A network is described for providing estimates of the current time. The network includes multiple computer systems each configured to provide an estimate of the current time in response to a received request. The computer systems are logically arranged to form a hierarchical structure, wherein the hierarchical structure includes multiple levels ranked with respect to one another. Each of the computer systems is assigned one of multiple levels of trust, and occupies one of the levels of the hierarchical structure dependent upon the assigned level of trust. The level of trust assigned to a given computer system is dependent upon a timekeeping dependability of the given computer system. The assigned level of trust may also be dependent upon a timekeeping security of the given computer system, where the timekeeping security is dependent upon a tamper resistance of the time clock of the given computer system. Methods for delegating a level of trust to a new computer system (i.e., a computer system not part of the network) and for adding a new computer system to the network are also described.