as

Poor quality pharmaceuticals in global public health Satoru Kimura, Yasuhide Nakamura

Online Resource




as

Multiscale modeling of vascular dynamics of micro- and nano-particles: application to drug delivery system / Huilin Ye, Zhiqiang Shen and Ying Li

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as

Nanoparticles induce oxidative and endoplasmic reticulum stresses: antioxidant therapeutic defenses / Loutfy H. Madkour

Online Resource




as

Statin-associated muscle symptoms Paul D. Thompson, Beth A. Taylor, editors

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as

Psychoactive medicinal plants and fungal neurotoxins Amritpal Singh Saroya, Jaswinder Singh

Online Resource




as

Novel drug delivery technologies: innovative strategies for drug re-positioning / Ambikanandan Misra, Aliasgar Shahiwala, editors

Online Resource




as

The role of NIH in drug development innovation and its impact on patient access: proceedings of a workshop / Francis K. Amankwah, Alexandra Andrada, Sharyl J. Nass, and Theresa Wizemann, rapporteurs ; Board on Health Care Services ; Board on Health Scienc

Online Resource




as

Strange trips: science, culture, and the regulation of drugs / Lucas Richert

Hayden Library - RM316.R53 2018




as

A Bit of Relief: Tea and Toast

“Quite honestly, one of the most disheartening things about American life is not the politics, not the incredible social division — it’s the way you make tea.”




as

Kashmir Gun Battle Kills at Least 7

Fighting between the Indian Army and militants threatened to heighten hostilities in the disputed region, where near-daily skirmishes have raged for weeks.




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As India Loosens Its Strict Lockdown, Coronavirus Deaths Jump Sharply

The streets have suddenly come alive, especially at night, in many areas where social distancing is impossible.




as

Top Kashmiri Militant Is Killed, Sparking Protests and Rage

Over years of fighting, Riyaz Ahmad Naikoo recruited scores of young Kashmiris in an armed quest for independence from India. His death has set off a fresh wave of unrest.




as

Gas Leak in India at LG Factory Kills 11 and Sickens Hundreds

Residents in eastern India woke up in the middle of the night surrounded by a cloud of styrene vapor. Many couldn’t breathe.




as

Fungus that causes bat-killing disease White-nose Syndrome is expanding in Texas

BCI announced today that early signs of the fungus Pseudogymnoascus destructans (Pd) have been detected at one of the world’s premier bat conservation sites, Bracken Cave Preserve




as

Beaches and Coasts, 2nd Edition


 

A new edition of a unique textbook that provides an exhaustive treatment of the world's different coasts—with focus on climate change sea-level rise 

Coastlines of the world are as diverse and complex as any geological setting on Earth, and understanding them is extremely important. Beaches and Coasts, Second Edition is an exciting and unique textbook that covers the world’s different coasts and details the highly varied processes that have shaped



Read More...




as

Gas Injection into Geological Formations and Related Topics, Volume 8


 
This is the eighth volume in the series, Advances in Natural Gas Engineering, focusing on gas injection into geological formations and other related topics, very important areas of natural gas engineering. This volume includes information for both upstream and downstream operations, including chapters detailing the most cutting-edge techniques in acid gas injection, carbon capture, chemical and thermodynamic models, and much more.


Read More...




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TinyCDN: a portable blazing fast CDN

In this blog post I am introducing tinyCDN, a middle-ware module and a standalone static file server that does much more than others, and it has been designed from the scratch to work on most constrained, Internet of Things, environments, as well as production server.




as

DOMClass To The Rescue!

In this Simplified Web Components via DOMClass post, I introduce a new project which aim is to bring Custom Elements in a Web Components fashion through an ES6 looking class syntax.

Enjoy the post, and the project ;)




as

Object.assign Side Effects and How To Copy

In How To Copy Objects post I'll explain the difference between various native ways to copy own keys and properties, describing also the fact that Object.assign is full of surprises and side effects.

As example, assigning to an object something like {get next() {return ++this.i}, i:0} instead of {i:0, get next() {return ++this.i}} will result in different values copied over: next === 1 and i === 1 in the first case, next === 1 and i === 0 in the second one.




as

Exporting modules in JavaScript

In my latest entry I explain the difference about exporting a module between server side or CLI environments such Nashorn, SpiderMonkey, JSC, or micro controller and embedded engines such Duktape, Espruino, KinomaJS, and Desktop UI space via GJS.
Using this is a universal way to attach and export properties but when it comes to ES2015 modules, incompatible with CommonJS and with an undefined execution context.
Enjoy




as

The missing analysis in JavaScript "Real" Mixins

I love hacks and unusual patterns! As logical consequence, I loved this post about "Real" Mixins!!!
The only hitch about that post is that I believe there are few points closer to a "gonna sell you my idea" discussion than a non disillusioned one.
Let's start this counter analysis remembering what are actually classes in latest JavaScript standard, so that we can move on explaining what's missing in there.

JavaScript embraces prototypal inheritance

It doesn't matter if ES6 made the previously reserved class keyword usable; at the end of the day we're dealing with a special syntactical shortcut to enrich a generic prototype object.

// class in ES2015
class A {
constructor() {}
method() {}
get accessor() {}
set accessor(value) {}
}

// where are those methods and properties defined?
console.log(
Object.getOwnPropertyNames(A.prototype)
// ["constructor", "method", "accessor"]
);
Accordingly, declaring a generic class consists in bypassing the following procedure:

function A() {}
Object.defineProperties(
A.prototype,
{
// constructor is implicitly defined
method: {
configurable: true,
writable: true,
value: function method() {}
},
accessor: {
configurable: true,
get: function get() {},
set: function set(value) {}
}
}
);
If you don't trust me, trust what a transpiler would do, summarized in the following code:

var A = (function () {
// the constructor
function A() {
_classCallCheck(this, _temporalAssertDefined(A, "A", _temporalUndefined) && A);
}
// the enriched prototype
_createClass(_temporalAssertDefined(A, "A", _temporalUndefined) && A, [{
key: "method",
value: function method() {}
}, {
key: "accessor",
get: function get() {},
set: function set(value) {}
}]);

return _temporalAssertDefined(A, "A", _temporalUndefined) && A;
})();
If there is some public static property in the definition, its assignment to the constructor would be the second bypassed part.

The super case

The extra bit in terms of syntax that makes ES6 special is the special keyword super. Being multiple inheritance not possible in JavaScript, we could think about super as the static reference to the directly extended prototype. In case of the previous B class, which extends A, we can think about super variable like if it was defined as such:

// used within the constructor
let super = (...args) => A.apply(this, arguments);

// used within any other method
super.method = (...args) => A.prototype.method.apply(this, args);

// used as accessor
Object.defineProperty(super, 'accessor', {
get: () => Object.getOwnPropertyDescriptor(
A.prototype, 'accessor'
).get.call(this),
set: (value) => Object.getOwnPropertyDescriptor(
A.prototype, 'accessor'
).set.call(this, value)
});
Now that we have a decent understanding on how inheritance works in JavaScript and what it means to declare a class, let's talk about few misleading points sold as pros or cons in the mentioned article.

Prototypes are always modified anyway!

We've just seen that defining a class technically means enriching its prototype object. This already invalidates somehow Justin point but there's more to consider.
When Justin exposes his idea on why current solutions are bad, he says that:
When using mixin libraries against prototype objects, the prototypes are directly mutated. This is a problem if the prototype is used anywhere else that the mixed-in properties are not wanted.
The way Justin describes this issue is quite misleading because mutating prototypes at runtime is a well known bad practice.
Indeed, I believe every single library he mentioned in that post, and he also forgot mine, is not designed to mutate classes prototypes at runtime ... like: not at all!
Every single mixin proposal that is capable of implementing mixins via classes is indeed designed to define these classes at definition time, not at runtime!
Moreover, whatever solution Justin proposed will not guard any class from being modified at runtime later on!
The same way he's defining his final classes during their definitions, mixins-for-classes oriented libraries have exactly the same goal: you define your class and its mixins during the class definition time!
The fact mixins add properties to a prototype is a completely hidden matter that at class definition time is everything but bad.
Also, no property is modified in place, because mixins are there to enrich, not to modify ... and having a prototype enriched means also that it's easier to spot name clashing and methods or properties conflicts ... but I'll come back to that later ...

super actually should NOT work!

The main bummer about the article is that it starts in a very reasonable way, describing mixins and classes, and also analyzing their role in a program.
The real, and only, difference between a mixin and normal subclass is that a normal subclass has a fixed superclass, while a mixin definition doesn't yet have a superclass.
Justin started right at the very beginning, and then degenerated with all sort of contradictions such:
Then finally he's back to Sanity Village with the following sentence:
super calls can be a little unintuitive for those new to mixins because the superclass isn't known at mixin definition, and sometimes developers expect super to point to the declared superclass (the parameter to the mixin), not the mixin application.
And on top of that, Justin talks about constructors too:
Constructors are a potential source of confusion with mixins. They essentially behave like methods, except that overriden methods tend to have the same signature, while constructors in a inheritance hierarchy often have different signatures.
In case you're not convinced yet how much messed up could be the situation, I'd like to add extra examples to the plate.
Let's consider the word area and its multiple meanings:
  • any particular extent of space or surface
  • a geographical region
  • any section reserved for a specific function
  • extent, range, or scope
  • field of study, or a branch of a field of study
  • a piece of unoccupied ground; an open space
  • the space or site on which a building stands
Now you really have to tell me in case you implement a basic Shape mixin with an area() method what the hack would you expect when invoking super. Moreoever, you should tell me if for every single method you are going to write within a mixin, you are also going to blindly invoke super with arbitrary amount of arguments in there ...

So here my quick advice about calling blindly a super: NO, followed by DON'T and eventually NEVER!

Oversold super ability

No kidding, and I can't stress this enough ... I've never ever in my life wrote a single mixin that was blindly trusting on a super call. That would be eventually an application based on mixins but that's a completely different story.
My feeling is that Justin tried to combine at all cost different concepts, probably mislead by his Dart background, since mentioned as reference, where composition in Dart was indeed classes based and the lang itself exposes native mixins as classes ... but here again we are in JavaScript!

instanceof what?

Another oversold point in Justin's article is that instanceof works.
This one was easy to spot ... I mean, if you create a class at runtime everytime the mixin is invoked, what exactly are you capable of "instanceoffing" and why would that benefit anyone about anything?
I'm writing down his very same examples here that will obviously all fail:

// a new anonymous class is created each time
// who's gonna benefit about the instanceof?
let MyMixin = (superclass) => class extends superclass {
foo() {
console.log('foo from MyMixin');
}
};

// let's try this class
class MyClass extends MyMixin(MyBaseClass) {
/* ... */
}

// Justin says it's cool that instanceof works ...
(new MyClass) instanceof MyMixin; // false
// false ... really, it can't be an instance of
// an arrow function prototype, isn't it?!
Accordingly, and unless I've misunderstood Justin point in which case I apologies in advance, I'm not sure what's the exact point in having instanceof working. Yes, sure the intermediate class is there, but every time the mixin is used it will create a different class so there's absolutely no advantage in having instanceof working there ... am I right?

Improving **Objects** Composition

In his Improving the Syntax paragraph, Justin exposes a very nice API summarized as such:

let mix = (superclass) => new MixinBuilder(superclass);

class MixinBuilder {
constructor(superclass) {
this.superclass = superclass;
}

with(...mixins) {
return mixins.reduce((c, mixin) => mixin(c), this.superclass);
}
}
Well, this was actually the part I've liked the most about his article, it's a very simple and semantic API, and it also doesn't need classes at all to be implemented for any kind of JS object!
How? Well, simply creating objects from objects instead:

let mix = (object) => ({
with: (...mixins) => mixins.reduce(
(c, mixin) => Object.create(
c, Object.getOwnPropertyDescriptors(mixin)
), object)
});
It could surely be improved in order to deal with classes too but you get the idea:

let a = {a: 'a'};
let b = {b: 'b'};
let c = {c: 'c'};
let d = mix(c).with(a, b);
console.log(d);
Since the main trick in Justin proposal is to place an intermediate class in the inheritance chain, defining at runtime each time the same class and its prototype, I've done something different here that doesn't need to create a new class with its own prototype or object each time, while preserving original functionalities without affecting them.

Less RAM to use, a hopefully coming soon native Object.getOwnPropertyDescriptors that should land in ES7 and make extraction faster, and the ability to use the pattern with pretty much everything out there, modern or old.
The gist is here, feel free to reuse.

As Summary ...

Wrapping up this post, with latter proposal we can actually achieve whatever Justin did with his intermediate classes approach but following different goals:
  1. Mixins are added to the prototype chain.
  2. Mixins are applied without modifying existing objects.
  3. Mixins do no magic, and don't define new semantics on top of the core language.
  4. super.foo property access won't hopefully work within mixins but it will with subclasses methods.
  5. super() calls won't hopefully work in mixins constructors because you've no idea what kind of arguments you are going to receive. Subclasses still work as expected.
  6. Mixins are able to extend other mixins.
  7. instanceof has no reason to be even considered in this scenario since we are composing objects.
  8. Mixin definitions do not require library support - they can be written in a universal style and be compatible with non classes based engines too.
  9. bonus: less memory consumption overall, there's no runtime duplication for the same logic each time
I still want to thanks Justin because he made it quite clear that still not everyone fully understands mixins but there's surely a real-world need, or better demand, in the current JavaScript community.

Let's hope the next version of ECMAScript will let all of us compose in a standard way that doesn't include a footgun like super through intermediate classes definition could do.
Thanks for your patience reading through this!




as

JavaScript Interfaces

In this Implementing Interfaces in JavaScript blog entry I'll show a new way to enrich prototypal inheritance layering functionalities a part, without modifying prototypes at all. A different, alternative, and in some case even better, approach to mixins.




as

module.import(async)

Using a de-facto standard like CommonJS is for modules, I've implemented a Promise based import after TC39 proposal, which also accepts promises based module.exports.

Backward compatible and deadly simple, this proposal needs some adoption in order to push it further at TC39 or NodeJS.

Don't miss the post!




as

Wildlife tourism, environmental learning and ethical encounters: ecological and conservation aspects / edited by Ismar Borges de Lima, Ronda J. Green

Online Resource




as

Frederick de Wit and the first concise reference atlas / George Carhart

Hayden Library - GA923.6.W57 C37 2016




as

The ArcGIS book: 10 big ideas about applying geography to your world / Christian Harder, editor

Rotch Library - G70.212.A7352 2015




as

Spatial big data science: classification techniques for Earth observation imagery / Zhe Jiang, Shashi Shekhar

Online Resource




as

A Louisiana coastal atlas: resources, economies, and demographics / Scott A. Hemmerling

Dewey Library - G1362.C6A5 H46 2017




as

Exploring Greenland: cold war science and technology on ice / Ronald E. Doel, Kristine C. Harper, Matthias Heymann, editors

Hayden Library - G743.E96 2016




as

The Oxford handbook of the prehistoric Arctic / edited by T. Max Friesen and Owen K. Mason

Hayden Library - G606.O94 2016




as

Geoparks and geo-tourism in Iran / edited by Andreas Dittmann

Rotch Library - G155.I65 G46 2017




as

Endeavouring Banks: exploring collections from the Endeavour voyage, 1768-1771 / Neil Chambers, with contributions by Anna Agnarsdottir, Sir David Attenborough, Jeremy Coote, Philip J. Hatfield and John Gascoigne

Hayden Library - G420.B18 C43 2016




as

Spatio-temporal graph data analytics / Venkata M. V. Gunturi, Shashi Shekhar

Online Resource




as

Atlas Obscura / Joshua Foer, Dylan Thuras & Ella Morton

Hayden Library - G465.F64 2016




as

Basic Principles of Topography by Blagoja Markoski

Online Resource




as

Atlas of global development.

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as

Asian youth travellers: insights and implications / Chateryn Khoo-Lattimore, Elaine Chao Ling Yang, editors

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as

Managing Asian destinations.

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as

The Palgrave Handbook of Sustainability: Case Studies and Practical Solutions / edited by Robert Brinkmann, Sandra J. Garren

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as

Tangible modeling with open source GIS / Anna Petrasova, Brendan Harmon, Vaclav Petras, Payam Tabrizian, Helena Mitasova

Online Resource




as

Exploration of subsurface Antarctica: uncovering past changes and modern processes / edited by M.J. Siegert, S.S.R. Jamieson and D.A. White

Hayden Library - G860.E97 2018




as

The solo travel handbook: practical tips and inspiration for a safe, fun and fearless trip / commissioning editors Jessica Cole, Sarah Reid ; editors Lucy Cheek, Kate Turvey ; assistant editor Christina Webb

Hayden Library - G151.S57 2018




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QGIS in remote sensing set / edited by Nicolas Baghdadi, Clément Mallet, Mehrez Zribi

Rotch Library - G70.212.Q45 2018




as

Imagery and GIS: best practices for extracting information from imagery / Kass Green, Russell G. Congalton, Mark Tukman

Rotch Library - G70.4.G743 2017




as

An historical geography of tourism in Victoria, Australia: case studies / Ian D. Clark (editor) ; managing editor, Lucrezia Lopez

Online Resource




as

Ecosystem Services for Well-Being in Deltas: Integrated Assessment for Policy Analysis / edited by Robert J. Nicholls, Craig W. Hutton, W. Neil Adger, Susan E. Hanson, Md. Munsur Rahman, Mashfiqus Salehin

Online Resource




as

Graphisch-statistischer Atlas der Schweiz / herausgegeben vom Statistischen Bureau des eidg. Departements des Innern = Atlas graphique et statistique de la Suisse / publié par le Bureau de statistique du Département fédéral de l'i

Hayden Library - G1896.E24 G46 1897a




as

The phantom atlas: the greatest myths, lies and blunders on maps / Edward Brooke-Hitching

Rotch Library - GA108.7.B76 2018




as

Understanding GIS: an ArcGIS Pro project workbook / David Smith, Nathan Strout, Christian Harder, Steven Moore, Tim Ormsby, Thomas Balstrøm

Rotch Library - G70.212.H358 2017




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GIS and the social sciences: theory and applications / Dimitris Ballas, Graham Clarke, Rachel S. Franklin and Andy Newing

Rotch Library - G70.212.B35 2018