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Potential neurotoxicity of 5-hydroxymethylfurfural and its oligomers: widespread substances in carbohydrate-containing foods

Food Funct., 2020, Advance Article
DOI: 10.1039/C9FO02526J, Paper
Cheng Wang, Zhenru Liu, Tian Hu, Youjia Li, Rui Liu, Junjie Zhang, Huaizhen He
5-Hydroxymethylfurfural (5-HMF) and its acid-catalyzed oligomers can inhibit nerve cell proliferation and induce neurological deficits at near or below the reported 24 h dietary intake of 5-HMF in humans.
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Alleviating effects of noni fruit polysaccharide on hepatic oxidative stress and inflammation in rats under a high-fat diet and its possible mechanisms

Food Funct., 2020, 11,2953-2968
DOI: 10.1039/D0FO00178C, Paper
Xiaobing Yang, Wenjing Mo, Chuanjin Zheng, Wenzhi Li, Jian Tang, Xiaoyong Wu
Non-alcoholic fatty liver disease is associated with gut microbiota, oxidative stress, and inflammation.
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Ergosterol peroxide from Pleurotus ferulae inhibits gastrointestinal tumor cell growth through induction of apoptosis via reactive oxygen species and endoplasmic reticulum stress

Food Funct., 2020, Advance Article
DOI: 10.1039/C9FO02454A, Paper
Yi Yang, Xiaoyu Luo, Mayila Yasheng, Jun Zhao, Jinyu Li, Jinyao Li
Ergosterol peroxide was purified from Pleurotus ferulae by silica gel chromatography, Sephadex LH-20 chromatography and recrystallization and named as PFEP, which was identified by ESI-MS and NMR.
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Flavonoids isolated from loquat (Eriobotrya japonica) leaves inhibit oxidative stress and inflammation induced by cigarette smoke in COPD mice: the role of TRPV1 signaling pathways

Food Funct., 2020, 11,3516-3526
DOI: 10.1039/C9FO02921D, Paper
Tunyu Jian, Jian Chen, Xiaoqin Ding, Han Lv, Jiawei Li, Yuexian Wu, Bingru Ren, Bei Tong, Yuanyuan Zuo, Kelei Su, Weilin Li
Total flavonoids isolated from loquat leaves inhibit inflammation and oxidative stress by regulating TRPV1 and the related pathway in cigarette smoke-induced COPD mice.
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Enzymatic hydrolysis of insect Alphitobius diaperinus towards the development of bioactive peptide hydrolysates

Food Funct., 2020, 11,3539-3548
DOI: 10.1039/D0FO00188K, Paper
Pedro Sousa, Sandra Borges, Manuela Pintado
Edible insects are a promising protein source for the future generation, due to their nutritional composition, sustainability and low environmental impact.
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The development of lentil derived protein–iron complexes and their effects on iron deficiency anemia in vitro

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00384K, Paper
Ezgi Evcan, Sukru Gulec
Lentil derived proteins have the capacity to chelate iron minerals and hydrolysed protein–iron complexes have functional properties on iron deficiency anemia in in vitro by influencing mRNA levels of iron regulating genes.
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A rapid protocol to distinguish between Citri Exocarpium Rubrum and Citri Reticulatae Pericarpium based on the characteristic fingerprint and UHPLC-Q-TOF MS methods

Food Funct., 2020, 11,3719-3729
DOI: 10.1039/D0FO00082E, Paper
Liqiang Shi, Rongjin Wang, Tianshu Liu, Jiajie Wu, Hongxu Zhang, Zhiqiang Liu, Shu Liu, Zhongying Liu
Citri Exocarpium Rubrum and Citri Reticulatae Pericarpium were successfully distinguished by the characteristic fingerprint and UHPLC-Q-TOF MS methods.
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Antihypertensive effects of Trichiurus lepturus myosin hydrolysate in spontaneously hypertensive rats

Food Funct., 2020, 11,3645-3656
DOI: 10.1039/C9FO02687H, Paper
Weiqing Fu, Peixin Wang, Hongqiang Wu, Zhigang Zhang, Hongliang Zeng, Yi Zhang, Baodong Zheng, Jiamiao Hu
In this study, the blood pressure-lowering effects of Trichiurus lepturus myosin hydrolysate (TMH) and its possible mechanism were investigated in spontaneously hypertensive rats (SHRs).
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Correction: Efficacy of proprietary Lactobacillus casei for anti-tuberculosis associated gastrointestinal adverse reactions in adult patients: a randomized, open-label, dose–response trial

Food Funct., 2020, 11,3751-3751
DOI: 10.1039/D0FO90017F, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Song Lin, Shanliang Zhao, Jiahong Liu, Jianwen Zhang, Chao Zhang, Haibo Hao, Yuxia Sun, Jing Cai, Yang Yang, Yan Ma, Yuanyuan Li, Jinyu Wang, Aiguo Ma
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Protective effect of ferulic acid on STZ-induced diabetic nephropathy in rats

Food Funct., 2020, 11,3706-3718
DOI: 10.1039/C9FO02398D, Paper
Min-you Qi, Xu-tao Wang, Hui-lin Xu, Zhang-liang Yang, Yin Cheng, Bin Zhou
Ferulic acid protects against diabetic nephropathy in STZ-induced rats by attenuating oxidative stress, inflammation, fibrosis and podocyte injury.
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The purification, structural characterization and antidiabetic activity of a polysaccharide from Anoectochilus roxburghii

Food Funct., 2020, 11,3730-3740
DOI: 10.1039/C9FO00860H, Paper
Yuntao Liu, Tingting Tang, Songqi Duan, Cheng Li, Qinlu Lin, Hejun Wu, Aiping Liu, Bin Hu, Dingtao Wu, Suqing Li, Li Shen, Wenjuan Wu
Anoectochilus roxburghii, a traditional Chinese medicinal herb, has been widely used for treating numerous chronic diseases.
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Usage of supercritical fluid techniques to obtain bioactive alkaloid-rich extracts from cherimoya peel and leaves: extract profiles and their correlation with antioxidant properties and acetylcholinesterase and α-glucosidase inhibitory activities

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00342E, Paper
Oscar Galarce-Bustos, Mª Teresa Fernández-Ponce, Antonio Montes, Clara Pereyra, Lourdes Casas, Casimiro Mantell, Mario Aranda
The wastes generated by cherimoya cultivation and processing industries should be contemplated as a valuable source of bioactive alkaloids, with potential in pharmaceutical applications for the treatment or prevention of chronic diseases.
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Comparison of the effects of resveratrol and its derivative pterostilbene on hepatic oxidative stress and mitochondrial dysfunction in piglets challenged with diquat

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00732C, Paper
Hao Zhang, Yanan Chen, Yueping Chen, Peilu Jia, Shuli Ji, Jianxiong Xu, Yue Li, Tian Wang
Pterostilbene is more effective than resveratrol in alleviating liver injury, facilitating redox status, and improving mitochondrial function of piglets.
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Bergaptol from blossoms of Citrus aurantium L. var. amara Engl inhibits LPS-induced inflammatory responses and ox-LDL-induced lipid deposition

Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/C9FO00255C, Paper
Chun-Yan Shen, Tian-Xing Wang, Jian-Guo Jiang, Chun-Ling Huang, Wei Zhu
Aberrant activation of inflammation and excess accumulation of lipids play pivotal roles in atherosclerosis (AS) progression. Constituents from Citrus aurantium Linn variant amara Engl (CAVA) were effectively investigated for their...
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Targets and Underlying Mechanisms for Sedative and Hypnotic Activities of Saponins from Semen Ziziphus jujube

Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/D0FO00098A, Paper
Chun-Yan Shen, Lin Wan, Jing-Jing Zhu, Jian-Guo Jiang
Semen Ziziphus jujube (SZJ) has been widely consumed as edible resources in China to treat insomnia disorders. However, the underlying mechanisms and potential therapeutic targets remained obscure. SZJ-I and SZJ-II...
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Effects of a β-type glycosidic polysaccharide from Flammulina velutipes on anti-inflammation and gut microbiota modulation in colitis mice

Food Funct., 2020, Advance Article
DOI: 10.1039/C9FO03017D, Paper
Ruiqiu Zhao, Yang Ji, Xin Chen, Anxiang Su, Gaoxing Ma, Guitang Chen, Qiuhui Hu, Liyan Zhao
Using the Flammulina velutipes polysaccharide (FVP) extracted from our previous study, herein, we investigated the improvement of this β-type glycosidic polysaccharide in alleviating dextran sodium sulfate-induced ulcerative colitis (UC) in mice.
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Effects of polysaccharides from wild morels on immune response and gut microbiota composition in non-treated and cyclophosphamide-treated mice

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00597E, Paper
Wenyan Huo, Zhengping Feng, Suying Hu, Langjun Cui, Ting Qiao, Lu Dai, Peng Qi, Liguang Zhang, Yu Liu, Junzhi Li
Polysaccharides from wild morels alter gut microbiota, increase the production of SCFAs and promote the proliferation of lymphocytes in mice.
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Superior hypoglycemic activity of mulberry lacking monosaccharides is accompanied by better activation of the PI3K/Akt and AMPK signaling pathways

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00427H, Paper
Xiao-Shan Long, Sen-Tai Liao, Peng Wen, Yu-Xiao Zou, Fan Liu, Wei-Zhi Shen, Teng-Gen Hu
Mulberry removed monosaccharides (FM) displayed better hypoglycemic activity than untreated mulberry (MP), which may be attributed the stronger effects of FM on activating PI3K/Akt and AMPK signaling pathways.
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Cytoprotective effects of a proprietary red maple leaf extract and its major polyphenol, ginnalin A, against hydrogen peroxide and methylglyoxal induced oxidative stress in human keratinocytes

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00359J, Paper
Chang Liu, Hao Guo, Joel A. Dain, Yinsheng Wan, Xing-Hua Gao, Hong-Duo Chen, Navindra P. Seeram, Hang Ma
Maplifa™ (a proprietary red maple leaves extract) and its major polyphenol, ginnalin A, exert skin protective effects against oxidative stress.
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Production of GABA-enriched idli with ACE inhibitory and antioxidant properties using Aspergillus oryzae: the antihypertensive effects in spontaneously hypertensive rats

Food Funct., 2020, Advance Article
DOI: 10.1039/C9FO02854D, Paper
Mohsen Zareian, Ehsan Oskoueian, Marjan Majdinasab, Bita Forghani
The present study aimed to develop a fermented food (idli) with enhanced γ-aminobutyric acid (GABA) and angiotensin I-converting enzyme (ACE) inhibitory properties using a GABA-producing fungus.
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Structural and physicochemical changes in almond milk during in vitro gastric digestion: impact on the delivery of protein and lipids

Food Funct., 2020, Advance Article
DOI: 10.1039/C9FO02465D, Paper
Xin Wang, Aiqian Ye, Harjinder Singh
The gastric digestion of almond milk in a human gastric simulator resulted in major structural and physicochemical changes. The changes had significant impact on the rate of delivery of protein and lipids to the small intestine.
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Physicochemical and antibacterial properties of fabricated ovalbumin-carvacrol gel nanoparticles

Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/D0FO00755B, Paper
Shengqi Rao, Guang-wei Xu, Huawei Zeng, Xiang-feng Zheng, Qin Hu, Qi-Yan Wang, Zhenquan Yang, Xin'An Jiao
The applications of carvacrol are limited due to its poor stability, water solubility, and high volatility; however, ovalbumin can be used to encapsulate hydrophobic molecules, improve their aqueous solubility, and...
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The effect of quercetin on endothelial cells is modified by heterocellular interactions

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00141D, Paper
Open Access
Sarka Tumova, Michael J. Houghton, Gary Williamson
Single cell-type models are useful for determining mechanisms, but in vivo, cell–cell interactions are important, and neighbouring cells can impact endothelial cell function.
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The cognitive effects of an acute wild blueberry intervention on 7 – 10 year olds using extended memory and executive function task batteries.

Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/C9FO02284H, Paper
Adrian Robert Whyte, Daniel J Lamport, Graham Schafer, Claire M. Williams
Evidence for the health benefits of blueberries is well documented. In particular memory and executive function benefits have both been found for children aged 7 – 10 in the 6...
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Enzyme reaction-guided identification of active components from the flowers of Sophora japonica var. violacea

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00625D, Paper
Yunci Zhang, Dongyu Gu, Shuai He, Jing Meng, Jifeng Wang, Yunxiao Wang, Yi Wang, Jing Tian, Yi Yang
The flower of S. japonica is a favorite food and used as traditional medicine.
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Jiaogulan tea (Gpostemma pentaphyllum) potentiates the antidiabetic effect of white tea via the AMPK and PI3K pathways in C57BL/6 mice

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00395F, Paper
Xiaoyan Xia, Jing Xu, Xude Wang, Hua Wang, Zhenchuan Lin, Keping Shao, LinLin Fang, Chenning Zhang, Yuqing Zhao
The use of plant-based beverages to interfere with the onset of diabetes may be a promising approach towards type 2 diabetes mellitus (T2DM).
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The Ameliorative Effect of Lactobacillus plantarum-12 on DSS-induced murine colitis

Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/D0FO00007H, Paper
MengYing Sun, YuJun Liu, Yinglong Song, Yuan Gao, Fujunzhu Zhao, Yanghe Luo, Fang Qian, Guangqing Mu, Yanfeng Tuo
Some lactobacilli strains can exert beneficial effects on host when ingested in an adequate dose, such as immunoregulation and anti-inflammatory activities. In this study, the survival abilities in simulated gastrointestinal...
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Lactobacillus fermentum CECT5716 prevents renal damage in NZBWF1 mice model of systemic lupus erythematosus

Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/D0FO00578A, Paper
Néstor de la Visitación, Iñaki Robles-Vera, Marta Toral, Francisco O’Valle, Javier Moleon, Manuel Gómez-Guzmán, Miguel Romero, Marcos Duarte, Manuel Sanchez, Rosario Jimenez, Juan Duarte
The aim of this work was to evaluate whether the immune-modulatory bacteria Lactobacillus fermentum CECT5716 (LC40) protects kidneys in a female mouse model of lupus with hypertension. Twenty-week-old NZBWF1 (lupus)...
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Cerebral effect of optimized Allium sativum oil-loaded chitosan nanorods: GC-MS analysis and in-vitro/in-vivo evaluation

Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/C9FO02911G, Paper
Rabab Kamel, Abeer Salama, Nesma Mohammed, Nermine Shaffie
The chemical constituents of Allium sativum (Garlic) oil were investigated using GC/Ms technique after silylation, and revealed the presence of several fatty acids and their esters. The most dominant was...
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Kinetic profile and urinary excretion of phenyl-γ-valerolactones upon consumption of cranberry: a dose-response relationship

Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/D0FO00806K, Paper
Claudia Favari, Pedro Mena, Claudio Curti, Geoffrey Istas, Christian Heiss , Daniele Del Rio, Ana Rodriguez-Mateos
Cranberries are a rich source of poly(phenols), mainly monomeric and oligomeric flavan-3-ols. However, information on the appearance of their main circulating microbial metabolites, namely phenyl-γ-valerolactones and phenylvaleric acid, is lacking...
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Hypoglycemic effects and modulation of gut microbiota of diabetic mice by saponin from Polygonatum sibiricum

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00428F, Paper
Jiayuan Luo, Yangyang Chai, Min Zhao, Qingqi Guo, Yihong Bao
Polygonatum sibiricum is a medicinal and homologous plant grown in China. The saponin in Polygonatum sibiricum has shown its good hypoglycemic performance, and it can be developed as functional foods and drugs with hypoglycemic effect.
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Unveiling the bioactivity potential of Allium triquetrum L. lipophilic fraction: chemical characterization and in vitro antibacterial activity against methicillin-resistant Staphylococcus aureus

Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/D0FO00769B, Paper
Samia Rabah, Kahina Kouachi, Patricia Ramos, Ana T. P. C. Gomes, Adelaide Almeida, Hayate Haddadi-Guemghar, Khodir Madani, Armando Silvestre, Sónia A. O. Santos
The lipophilic composition of Allium triquetrum L. bulbs, flowers and leaves was studied for the first time, by GC-MS. Sixty-two compounds were firstly identified in A. triquetrum L. Fatty acids...
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Effects of compound K, a metabolite of ginsenosides, on memory and cognitive dysfunction in db/db mice involve the inhibition of ER stress and the NLRP3 inflammasome pathway

Food Funct., 2020, Advance Article
DOI: 10.1039/C9FO02602A, Paper
Chu-Wen Li, Min-Zhen Deng, Zhi-Jie Gao, Yuan-Ye Dang, Guo-Dong Zheng, Xiu-Juan Yang, Ying-Xin Chao, Ye-Feng Cai, Xiao-Li Wu
The metabolite of ginsenosides, compound K improves memory and cognitive dysfunction in diabetes mellitus mice.
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Evaluation of Tenebrio molitor protein as a source of peptides for modulating physiological processes

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00734J, Paper
Fernando Rivero Pino, Raúl Pérez Gálvez, F. Javier Espejo Carpio, Emilia M. Guadix
Tenebrio molitor hydrolysates produced with commercial proteases showed improved ACE inhibitory and antioxidant properties. This source could be employed as functional ingredient in food preparations.
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Mechanisms for Lactobacillus rhamnosus treatment of intestinal infection by drug-resistant Escherichia coli

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00128G, Paper
Na Li, Bing Pang, Junjun Li, Guanwen Liu, Xiaoguang Xu, Dongyan Shao, Chunmei Jiang, Baowei Yang, Junling Shi
Reducing the viability of pathogens may also play an important role for the therapeutic effects of Lactobacillus rhamnosus SHA113 against multiple-drug-resistant E. coli, as well as influencing on the intestinal integrity and functions of animals.
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Dietary supplementation of L-arginine and N-carbamylglutamate enhances duodenal barrier and mitochondrial functions and suppresses duodenal inflammation and mitophagy in suckling lambs suffering from intrauterine-growth-restriction

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00019A, Paper
Hao Zhang, Yi Ma, Mengzhi Wang, Mabrouk Elsabagh, Juan J. Loor, Hongrong Wang
The work aimed at investigating the effects of N-carbamylglutamate (NCG) or L-arginine (Arg) supplementation on the duodenal mitophagy, inflammation, and barrier function in suckling lambs suffering from intrauterine-growth-retardation (IUGR).
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The role of extensional rheology in the oral phase of swallowing: an in vitro study

Food Funct., 2020, Advance Article
DOI: 10.1039/C9FO02327E, Paper
Marco Marconati, Marco Ramaioli
In vitro swallowing experiments suggest that thin, viscoelastic liquids with strong apparent extensional viscosity lead to fast transit, lower oral residues and a compact bolus leaving the oral cavity.
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Influences of dietary starch structure on intestinal morphology, barrier functions, and epithelium apoptosis in weaned pigs

Food Funct., 2020, Advance Article
DOI: 10.1039/C9FO02652E, Paper
Open Access
Xiaoqian Gao, Bing Yu, Jie Yu, Xiangbing Mao, Zhiqing Huang, Yuheng Luo, Junqiu Luo, Ping Zheng, Jun He, Daiwen Chen
The objective of the present study was to evaluate the effects of dietary starch structure on intestinal health of weaned pigs by determining the intestinal morphology, barrier functions, epithelium apoptosis and digestive enzymes.
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Supplementation of Bacillus amyloliquefaciens AS385 culture broth powder containing 1-deoxynojirimycin in a high-fat diet altered the gene expressions related to lipid metabolism and insulin signaling in mice epididymal white adipose tissue

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00271B, Paper
Isabella Supardi Parida, Soo Takasu, Junya Ito, Ryoichi Ikeda, Kenji Yamagishi, Toshiyuki Kimura, Takahiro Eitsuka, Kiyotaka Nakagawa
Supplementation of Bacillus amyloliquefaciens AS385 culture broth powder in high-fat diet restored adiposity, glucose tolerance and insulin sensitivity in mice.
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Deciphering calcium-binding behaviors of casein phosphopeptides by experimental approaches and molecular simulation

Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/D0FO00844C, Paper
Minna Luo, Jie Xiao, Shengwei Sun, Fengchao Cui, Wei Li, Guo Liu, Yunqi Li, Yong Cao
Although specific groups in casein phosphopeptides (CPPs) have been identified to be essential for the calcium-binding capacity, how calcium binds with CPPs remains unclear. In the present study, experimental methods...
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The milk macromolecular peptide: preparation and evaluation of antihypertensive activity in rats

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00151A, Paper
Pengfei Cui, Xue Yang, Yunliang Li, Qiufang Liang, Yucheng Wang, Feng Lu, John Owusu, Shanfen Huang, Xiaofeng Ren, Haile Ma
In order to avoid the discomfort of digesting milk protein and make full use of the gastrointestinal digestive function, a milk macromolecular peptide was prepared with ACE inhibitory activity after gastrointestinal digestion as the index.
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Polysaccharides from Enteromorpha prolifera protect against carbon tetrachloride-induced acute liver injury in mice via activation of Nrf2/HO-1 signaling, and suppression of oxidative stress, inflammation and apoptosis

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00575D, Paper
Fuchuan Guo, Xinyun Zhuang, Mengyuan Han, Wenting Lin
EPP protected against hepatic injury induced by CCl4-derived reactive intermediates through the suppression of hepatic oxidative stress, inflammation, and apoptosis.
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Effects of gastrodin against carbon tetrachloride induced kidney inflammation and fibrosis in mice associated with the AMPK/Nrf2/HMGB1 pathway

Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/D0FO00711K, Paper
J. Q. Ma, Yun-Zhi Sun, Qing-Lei Ming, Zhi-Kai Tian, Yu-Jia Zhang, Chan-Min Liu
Gastrodin (GAS), the main phenolic glycoside extracted from Gastrodia elata Blume, exhibited potential renoprotective properties. Here we examined the protective effects of GAS against carbon tetrachloride (CCl4)-induced kidney inflammation and...
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Protective effects of Bifidobacterium adolescentis on collagen-induced arthritis in rats depend on timing of administration

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00077A, Paper
Zhexin Fan, Bo Yang, R. Paul Ross, Catherine Stanton, Guoxun Shi, Jianxin Zhao, Hao Zhang, Wei Chen
Early probiotics adminitration is a key timing to alleviate inflammation in rats with arthritis.
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Pausing SIP set to become simpler; more fund houses to offer option

Many fund houses don't yet offer the pause facility but are scrambling to put one in place for investors




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Flipkart, ICICI Lombard offer health plan for Covid-19 with instant claim

'Covid-19 Protection Cover' provides an instant Rs 25,000 benefit plan for to the customer if he tests positive for Covid-19




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Investment strategy: Benefit from the collective wisdom of markets

By going with ETFs, you eliminate decision-making, and emotional biases that come into play when picking active funds




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Senior citizens may see spike in premiums in wake of Covid-19 crisis

Since they are more vulnerable, medical insurers may become more wary




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Lockdown 2.0: Govt extends renewal of health, motor policies till May 15

If the renewal of motor third party and health policy falls due between March 25 and May 3, the lockdown period, then policyholders can make the renewal payment on or before May 15




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Avoid banks and NBFCs with high proportion of unsecured and SME loans

Longer-term investors with a three-five-year horizon have an opportunity to pick quality stocks, which in calmer times tend to trade at exorbitant valuations