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Arylsulfonyl histamine derivatives as powerful and selective α-glucosidase inhibitors

RSC Med. Chem., 2020, 11,518-527
DOI: 10.1039/C9MD00559E, Research Article
M. I. Osella, M. O. Salazar, M. D. Gamarra, D. M. Moreno, F. Lambertucci, D. E. Frances, R. L. E. Furlan
N α,Nτ-Di-4-trifluorobenzenesulfonyl histamine inhibits α-glucosidase in vitro reversibly and selectively with a Ki value of 11.6 μM, and shows an in vivo hypoglycemic effect in mice.
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Chemotherapy for human schistosomiasis: how far have we come? What's new? Where do we go from here?

RSC Med. Chem., 2020, 11,455-490
DOI: 10.1039/D0MD00062K, Review Article
Godwin Akpeko Dziwornu, Henrietta Dede Attram, Samuel Gachuhi, Kelly Chibale
After a century since the first antimonial-based drugs were introduced to treat the disease, anti-schistosomiasis drug development is again at a bottleneck with only one drug, praziquantel, available for treatment purposes.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Computer-aided discovery of phenylpyrazole based amides as potent S6K1 inhibitors

RSC Med. Chem., 2020, Advance Article
DOI: 10.1039/C9MD00537D, Research Article
Yan Yin, Yuxing Sun, Lianhua Zhao, Jinpeng Pan, Yangbo Feng
Ribosomal protein S6 kinase beta-1 (S6K1) is an attractive therapeutic target.
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The content of this RSS Feed (c) The Royal Society of Chemistry




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'F1 season likely to hit glitch'

'If we want to go to Asia, or America, I think it's going to be when we get on planes and have to fly overseas where I think the risk will start to potentially get greater.'




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Rütteldruckverdichtung als Plastodynamisches Problem: Deep vibration compaction as plastodynamic problem / W. Fellin

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Performance measures in snow and ice control operations / ICF with Athey Creek Consultants and Vaisala Inc

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Hydraulic rubber dam: an effective water management technology / edited by Sabu Thomas, Ajay Vasudeo Rane, Abitha V.K., Krishnan Kanny, Aastha Dutta

Barker Library - TC540.H937 2019




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Siliciclastic reserviors of the Arabian Plate / Edited by H. R. AlAnzi, R. A. Rahmani, R. J. Steel, O. M. Soliman

Dewey Library - TN876.A1 S55 2019




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Design of concrete bridge beams prestressed with CFRP systems / Abdeldjelil Belardi, Mina Dawood, Prakash Poudel [and five others]

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Building a multimodal future: connecting real estate development and transportation demand management to ease gridlock / Justin B. Schor, Federico Tallis

Rotch Library - HE308.S36 2019




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Global aspects of reputation and strategic management / editied by David L. Deephouse, Naomi A. Gardberg, and William Newburry

Dewey Library - HD30.28.G56 2019




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Street fights in Copenhagen: bicycle and car politics in a green mobility city / Jason Henderson and Natalie Marie Gulsrud

Rotch Library - HE311.D42 C6636 2019




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Performance of longitudinal barriers on curved, superelevated roadway sections / Dhafer Marzougui; Cing-Dao "Steve" Kan; Umashankar Mahadevaiah; Fadi Tahan; Christopher Story; Stefano Dolci; Alberto Moreno; Kenneth S. Opiela; Richard Powers

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Reproduction: antiquity to the present day / edited by Nick Hopwood, Rebecca Flemming, Lauren Kassell

Hayden Library - RG136.R477 2018




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TRANSBALTICA XI: transportation science and technology: proceedings of the International Conference TRANSBALTICA, May 2-3, 2019, Vilnius, Lithuania / edited by Kasthurirangan Gopalakrishnan, Olegas Prentkovskis, Irina Jackiva, Raimundas Junevičius

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Measuring, characterizing, and reporting pavement roughness of s / Steven M. Karamihas, Mark E. Gilbert, Michelle A. Barnes, Rohan W. Perera

Barker Library - TE7.N25 2019




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Structural failure: technical, legal and insurance aspects: proceedings of the founding symposium of the International Society for Technology, Law and Insurance, 18-19 November 1993, Vienna, Austria / edited by H.P. Rossmanith

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GIS-based simulation and analysis of intra-urban commuting / Yujie Hu, Fahui Wang

Rotch Library - HE305.H8 2019




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Technical, technological and economical aspects of thin-seams coal mining: International Mining Forum 2007 / [edited by] Eugeniusz J. Sobczyk, Jerzy Kicki

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Sustainability management and business strategy in Asia / editors, Katsuhiko Kokubu, Yoshiyuki Nagasaka

Dewey Library - HD30.255.S869 2020




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What's your problem?: identifying and solving the five types of process problems / Kicab Castañeda-Méndez

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Barker Library - TE7.N275 no.925




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The SMP concept-based 3D constitutive models for geomaterials / Hajime Matsuoka, De'an Sun

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Ultrasonic treatment of light alloy melts / by G I Eskin

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Unsaturated soils: proceedings of the 4th Asia Pacific Conference on Unsaturated Soils, Newcastle, Australia, 23- 25 November 2009 / editors, O. Buzzi, S. Fityus & D. Sheng

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Transit: a history of mass transit in the Puget Sound Region / by Jim Kershner

Dewey Library - HE4487.P84 K47 2019




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Field verification of proposed changes to the AASHTO R 30 procedures for laboratory conditioning of asphalt mixtures / David Newcomb, Edith Arámbula-Mercado, Amy Epps Martin, Mengge Yuan, Texas A&M Transportation Institute; Nam Tran, Fan Yin, Na

Barker Library - TE7.N25 no.919




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The sand compaction pile method / Masaki Kitazume

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Better buses, better cities: how to plan, run, and win the fight for effective transit / Steven Higashide

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Geopolitics of the Knowledge-Based Economy / Sami Moisio

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Offshore risk assessment.: Principles, modelling and applications of QRA studies / Jan-Erik Vinnem, Willy Røed

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Offshore Risk Assessment.: Principles, Modelling and Applications of QRA Studies / Jan-Erik Vinnem, Willy Røed

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Constitutive modelling and failure prediction for silicone adhesives in façade design Michael Drass

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Rain Loads: Guide to the rain load provisions of ASCE 7-16 / by Michael O'Rourke, et al

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Frost action in soils: fundamentals and mitigation in a changing climate / prepared by the Frozen Ground Committee and the Transportation and Infrastructure Committee of the Cold Regions Engineering Division of the American Society of Civil Engineers ; ed

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Engineering methods for precipitation under a changing climate / edited by J. Rolf Olsen, Ph.D., Kelcy Takahashi Adamec, P.E

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Risk-based structural evaluation methods: best practices and development of standards / Michel Ghosn, Graziano Fiorillo, Ming Liu, and Bruce Ellingwood

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Obstetric anesthesia: a case-based and visual approach / Thomas L. Archer, editor

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Train aerodynamics: fundamentals and applications / Chris Baker, Terry Johnson, Dominic Flynn, Hassan Hemida, Andrew Quinn, David Soper, Mark Sterling

Barker Library - TF550.B35 2019




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Impacts of policy-induced freight modal shifts / Rensselaer Polytechnic Institute, Jack Faucett Associates, Inc

Barker Library - HE199.A2 I366 2019




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Marine oil and gas exploration in China / Yongsheng Ma

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Secure knowledge management in artificial intelligence era: 8th International Conference, SKM 2019, Goa, India, December 21-22, 2019, proceedings / Sanjay K. Sahay, Nihita Goel, Vishwas Patil, Murtuza Jadliwala (eds.)

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Aligning Lean and value-based management: operations and financial functions at the system level / Gerd Kaufmann

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