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Rapid and green quantification of phloridzin and trilobatin in Lithocarpus litseifolius (Hance) Chun (sweet tea) using an online pressurized liquid extraction high-performance liquid chromatography at equal absorption wavelength method

By pubs.rsc.org
Published On ::

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00170B, Paper
Zhengming Qian, Qinggui Lei, Dan Tang, Guoying Tan, Qi Huang, Fucai Zhou, Wenhao Wang
Sweet tea is a functional herbal tea with anti-inflammatory, anti-diabetic, and other effects, in which phloridzin and trilobatin are two functional compounds.
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Luminescent and time-resolved determination of gemifloxacin mesylate in pharmaceutical formulations and spiked blood plasma samples using a lanthanide complex as a probe

By pubs.rsc.org
Published On ::

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00236A, Paper
Gasser M. Khairy, Rania M. Goda, Zeinab M. Anwar, Mohamed M. Aboelnga, Axel Duerkop
A new luminescent europium probe for the determination of the antibiotic gemifloxacin is presented. Time-resolved luminescence enables its quantitation in pharmaceutical formulations and blood samples.
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PCB-C4D coupled with paper-based microfluidic sampling for the rapid detection of liquid conductivity

By pubs.rsc.org
Published On ::

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00198B, Paper
Mingpeng Yang, Mingyi Cao, Zhixuan Zhang, Chaofan Wang
A solution conductivity detection method, using PCB-C4D coupled with paper-based microfluidic sampling, has been proposed for the rapid and in situ analysis of raw solution with particle filtration, improving detection consistency and reliability.
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A Rapid and Sensitive Aptamer-Based Biosensor for Beta-lactoglobulin in milk

By pubs.rsc.org
Published On ::

Anal. Methods, 2024, Accepted Manuscript
DOI: 10.1039/D4AY00460D, Paper
Anqi Liu, Meng Jiang, Yuyin Wu, Han Guo, Ling Kong, Zhiwei Chen, Zhaofeng Luo
β-Lactoglobulin, a naturally occurring milk protein and a major cause of milk allergy in infants, was the focus of this study. A highly selective, sensitive, and cost-effective BLI biosensor was...
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Simple and convenient preconcentration procedure for the isotopic analysis of uranium in seawater

By pubs.rsc.org
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Anal. Methods, 2024, Advance Article
DOI: 10.1039/D3AY01381B, Paper
Minami Abe, Noriaki Seko, Hiroyuki Hoshina, Shigeki Wada, Shinya Yamasaki, Keisuke Sueki, Aya Sakaguchi
Amidoxime adsorbent was synthesised by graft polymerisation. The adsorbent was efficient for collection of U in seawater for both the adsorption and desorption steps, thus affording a new strategy for measurement of U isotopes.
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Rapid detection of monkeypox virus and differentiation of West African and Congo Basin strains using endonuclease restriction-mediated real-time PCR-based testing

By pubs.rsc.org
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Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00492B, Paper
Juan Zhou, Fei Xiao, Xiaolan Huang, Jin Fu, Nan Jia, Chunrong Sun, Min Chen, Zheng Xu, Hui Huang, Yi Wang
A novel multiplex ET-PCR assay that integrates PCR amplification, restriction endonuclease cleavage and real-time fluorescence detection was devised to diagnose MPXV infection and distinguish the Congo Basin and West Africa MPXV strains.
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Statistical approaches to Raman imaging: principal component score mapping

By pubs.rsc.org
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Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00171K, Paper
Open Access
Elia Marin, Davide Redolfi Bristol, Alfredo Rondinella, Alex Lanzutti, Pietro Riello
We propose and benchmark test a universal protocol for the analysis of huge Raman imaging datasets, by applying PCA on raw, unprocessed data.
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Characterizing a visual lateral flow device for rapid SARS-CoV-2 virus protein detection: pre-clinical and system assessment

By pubs.rsc.org
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Anal. Methods, 2024, Advance Article
DOI: 10.1039/D3AY02075D, Paper
Natpapas Wiriyachaiporn, Jetnapang Kongrueng, Kannika Sukkuea, Rattana Tanrattanawong, Jarunee Vanichtanankul, Thanaya Saeyang, Tararat Jantra, Deanpen Japrung, Weerakanya Maneeprakorn, Suwussa Bamrungsap, Pareena Janchompoo, Ekawat Pasomsub
Analytical and pre-clinical evaluation of a visual screening lateral flow device for SARS-CoV-2 virus protein detection and its system characterization.
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An immunochromatographic strip sensor for rapid and sensitive detection of candesartan, olmesartan medoxomil, and irbesartan in herbal beverages

By pubs.rsc.org
Published On ::

Anal. Methods, 2024, 16,2359-2367
DOI: 10.1039/D4AY00151F, Paper
Dingyu Li, Aihong Wu, Liqiang Liu, Hua Kuang, Chuanlai Xu, Xiaoling Wu
Sartans, as a class of antihypertensive drugs, pose a threat to human health when illegally added to herbal beverages.
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A simple and rapid colorimetric detection of Staphylococcus Aureus relied on the distance-dependent optical properties of silver nanoparticles

By pubs.rsc.org
Published On ::

Anal. Methods, 2024, Accepted Manuscript
DOI: 10.1039/D3AY02189K, Paper
Ngoc Anh Thu Phan, Hoang Men Nguyen, Cam Duyen Thi Vo, Toi Vo Van, Phuoc Long Truong
The quick and accurate diagnosis of pathogens has appeared as a pressing issue in clinical diagnostics, environmental monitoring, and food safety. The current assays are suffering from limited capacities in...
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Filestack: A File Uploader and Powerful APIs to Deliver and Transform App Content

By www.impressivewebs.com
Published On :: Wed, 11 May 2022 10:00:00 +0000

[Sponsored] If you’re building an app that requires a lot of user-generated content and media that needs to be processed, tagged, filtered, or otherwise manipulated in real-time, you definitely want a solution that’s fast and seamless and doesn’t get in the way of your app’s primary functionality. Filestack is a service you’ll want to consider. Here’s what Filestack offers:

The post Filestack: A File Uploader and Powerful APIs to Deliver and Transform App Content appeared first on Impressive Webs.


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Pictures from the dear departed

By www.thehindubusinessline.com
Published On :: Thu, 19 Sep 2013 16:09:14 +0530


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Clarity of vision: On eye drops for presbyopia and ‘claims’

By www.thehindu.com
Published On :: Tue, 17 Sep 2024 00:15:00 +0530

A useful drug is undone by fantastic claims about its efficacy


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Pivot to watch: On the U.S. Fed’s rate reduction, its impact

By www.thehindu.com
Published On :: Sat, 21 Sep 2024 00:10:00 +0530


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​Flipping scripts: On the Haryana and J&K election results  

By www.thehindu.com
Published On :: Wed, 09 Oct 2024 00:20:00 +0530

BJP and INDIA bloc emerge clear winners in Haryana and Jammu & Kashmir


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Design, synthesis and biological evaluation of a novel PSMA–PI3K small molecule drug conjugate

By pubs.rsc.org
Published On ::

RSC Med. Chem., 2024, 15,3485-3494
DOI: 10.1039/D4MD00246F, Research Article
Shouguo Peng, Haixia Li, Weilu Cui, Tianning Xiong, Jiaqi Hu, Haixiang Qi, Songwen Lin, Deyu Wu, Ming Ji, Heng Xu
A novel PSMA–PI3K small molecule drug conjugate has been prepared, highlighting its potential in targeted cancer therapy.
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A novel, glutathione-activated prodrug of pimasertib loaded in liposomes for targeted cancer therapy

By pubs.rsc.org
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RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00517A, Research Article
Open Access
Arianna Amenta, Susanna Comi, Marcelo Kravicz, Silvia Sesana, Antonia Antoniou, Daniele Passarella, Pierfausto Seneci, Sara Pellegrino, Francesca Re
A novel, glutathione-activated prodrug of pimasertib (PROPIMA) has been developed. PROPIMA showed ability to inhibit tumour cell migration and proliferation controlled over time, while also achieving a high incorporation rate into liposomes.
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Design, synthesis, and structure–activity relationship studies of 6H-benzo[b]indeno[1,2-d]thiophen-6-one derivatives as DYRK1A/CLK1/CLK4/haspin inhibitors

By pubs.rsc.org
Published On ::

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00537F, Research Article
Open Access
Abdelfattah Faouzi, Alexandre Arnaud, François Hallé, Jean Roussel, Mandy Aymard, Vincent Denavit, Cong Viet Do, Angélique Mularoni, Mohamed Salah, Ahmed ElHady, Thanh-Nhat Pham, Alexandre Bancet, Marc Le Borgne, Raphaël Terreux, Roland Barret, Matthias Engel, Thierry Lomberget
A series of sulfur-containing tetracycles was designed and evaluated for their ability to inhibit protein kinase DYRK1A, a target known to have several potential therapeutic applications including cancers, Down syndrome or Alzheimer's disease.
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Design, synthesis, and evaluation of benzhydrylpiperazine-based novel dual COX-2/5-LOX inhibitors with anti-inflammatory and anti-cancer activity

By pubs.rsc.org
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RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00471J, Research Article
Poorvi Saraf, Bhagwati Bhardwaj, Akash Verma, Mohammad Aquib Siddiqui, Himanshu Verma, Pradeep Kumar, Samridhi Srivastava, Sairam Krishnamurthy, Saripella Srikrishna, Sushant Kumar Shrivastava
Screening piperazine derivatives via ChEMBL database led to the design and synthesis of novel dual COX-2/5-LOX inhibitors with strong anti-inflammatory, analgesic, and anti-cancer activity.
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Modulating polybasic character of galactose-based glycosylated antitumor ether lipids for enhanced cytotoxic response

By pubs.rsc.org
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RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00662C, Research Article
Rajat Arora, Ayan Mukherjee, Gilbert Arthur, Mark W. Nachtigal, Frank Schweizer
We describe the multi-step synthesis of different dibasic and tribasic galactosamine-based glycosylated antitumor ether lipids (GAELs) and their cytotoxic response in comparison to doxorubicin and cisplatin.
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Miniaturized click chemistry and direct screening facilitate the discovery of triazole piperazine SARS-CoV-2 Mpro inhibitors with improved metabolic stability

By pubs.rsc.org
Published On ::

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00555D, Research Article
Shenghua Gao, Letian Song, Bing Ye, Mianling Yang, Junyi Li, Manyu Gu, Ann E. Tollefson, Karoly Toth, Peng Zhan, Xinyong Liu
The continuous mutational nature of SARS-CoV-2 and its inter-species' similarities emphasize the urgent need to design and develop more direct-acting antiviral agents against highly infectious variants.
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Light enhanced cytotoxicity and antitumoral effect of a ruthenium-based photosensitizer inspired from natural alkaloids

By pubs.rsc.org
Published On ::

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00600C, Research Article
Open Access
Gennaro Sanità, Maria Laura Alfieri, Barbara Carrese, Serena Damian, Vincenza Mele, Gaetano Calì, Brigida Silvestri, Sebastiano Marra, Susan Mohammadi, Giuseppina Luciani, Paola Manini, Annalisa Lamberti
Biological assays carried out on melanoma and breast cancer cells highlighted the role of light in boosting the cytotoxic effect of a ruthenium complex featuring a dihydroisoquinoline ligand suggesting applications in photodynamic therapy.
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Doctor assaulted inside Tiruchi ESI Hospital

By www.thehindu.com
Published On :: Tue, 05 Nov 2024 18:29:04 +0530


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Three arrested for assaulting doctor in ESI hospital

By www.thehindu.com
Published On :: Wed, 06 Nov 2024 19:23:47 +0530


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Pumping stations to be set up in eight low-lying areas in Tiruchi to prevent inundation

By www.thehindu.com
Published On :: Wed, 06 Nov 2024 19:30:58 +0530


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Uppiliyapuram, gateway to scenic Pachamalai, lacks bus stand with passengers left to fight the elements

By www.thehindu.com
Published On :: Fri, 08 Nov 2024 19:20:03 +0530

Buses stop at a busy junction making it difficult for commuters as well as local businessmen; a site is yet to be identified for the bus stand


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Two doctors posted at Uppiliyapuram UPHC

By www.thehindu.com
Published On :: Fri, 08 Nov 2024 20:29:46 +0530


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548: Infinite Canvas, Luro + Figma, and Scraping or Crawling

By shoptalkshow.com
Published On :: Mon, 16 Jan 2023 10:41:42 +0000

What's going to happen to homework with AI? Thoughts on infinite canvas which leads into Luro and Sigma integration, and Chris gets nerdsniped and tries to scrap (or should he crawl?) websites for data.


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570: Haircut Maintenance, Dave’s Bookshelf, Lazy Loading, and APIs

By shoptalkshow.com
Published On :: Mon, 19 Jun 2023 08:00:42 +0000

We're talking Dave's new haircut, playing Hondo, what Dave uses for images on his bookshelf page, lazy-loading thoughts, vh vw follow up, eyeball tracking updates, loading website with js, Vue transitions, charging for API access, and do you cross post, one post, or no post on social media in 2023?


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579: One Day Builds, Spicy Slugs, and What Next for CSS?

By shoptalkshow.com
Published On :: Mon, 21 Aug 2023 20:00:21 +0000

Have you ever been an auctioneer? Sometimes when God closes a shed, he opens a sauna. Dave's working on the one day build theory, how to market with fake data, an update on the Discord, marketing with a spicy slug, what we want to see next in CSS, and thoughts on component libraries.


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594: Wiping Your Laptop, UX of Password Codes, and :Has Tips and Tricks

By shoptalkshow.com
Published On :: Mon, 04 Dec 2023 09:15:20 +0000

In this episode we're discussing making tech videos, website tinkering, :has tricks, SVG path commands, and the complexities of CSS & JavaScript logic.


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603: Deno, React Alternatives, and Copilot Concerns with Triple Threat Josh Collinsworth

By shoptalkshow.com
Published On :: Mon, 19 Feb 2024 09:22:07 +0000

Josh (or Jsoh) stops by to talk about his work at Deno, recent blog posts on Copilot, why Svelte is awesome and React is not, Apple and PWA, and building word games on the web.


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620: Cloudflare #HotDrama, Auth, and Prototyping Thoughts

By shoptalkshow.com
Published On :: Mon, 17 Jun 2024 08:27:24 +0000

Show DescriptionWe dive a bit deeper into the Cloudflare drama of the past couple of weeks, Instagram ads vs Cara art, what to do about Auth in your app, pre-negging any sponsorships, prototyping and feedback on projects, and ideas for future topics. Listen on Website →Links Cloudflare took down our website after trying to force […]


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623: Assigning Weight Dynamically, CoPilot vs Other AI, and Monorepos

By shoptalkshow.com
Published On :: Mon, 08 Jul 2024 08:34:45 +0000

We're talking about assigning a weight to items in a layout, differentiating between banger posts and regular blog posts, using social engineering to get PR's accepted, monorepo thoughts, using CoPilot vs other AI programming support bots, has TypeScript benefited from AI, and what happens if you turn off CoPilot?


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F1: Piastri on pole as McLaren in front

By www.rediff.com
Published On ::

McLaren are leading the constructor's championship but are only 29 points ahead of Ferrari, with Leclerc an obvious threat and team mate Carlos Sainz qualifying fifth and Mercedes' George Russell sixth.


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Keeping track of Scope-3 emissions from supply chains

By www.thehindubusinessline.com
Published On :: Sun, 27 Oct 2024 18:58:37 +0530

Gurgaon-based startup OnlyGood FutureTech helps companies measure emissions generated by supply partners


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Nvidia: The lynchpin of the AI revolution

By www.thehindubusinessline.com
Published On :: Sat, 09 Nov 2024 18:18:47 +0530

The meteoric rise of the Santa Clara-headquartered chipmaker is powered by bold innovation


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IAF Mig-29 fighter crashes near Agra, pilot ejects to safety

By www.thehindu.com
Published On :: Mon, 04 Nov 2024 17:26:14 +0530

An enquiry has been ordered by the IAF, to ascertain the cause of the accident


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Three arrested for raping intellectually disabled research scholar from Odisha

By www.thehindu.com
Published On :: Fri, 08 Nov 2024 01:09:38 +0530


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Delhi cop Nidhin Valsan’s inspiring journey from arresting cancer to Ironman finish line

By www.thehindu.com
Published On :: Fri, 08 Nov 2024 02:05:22 +0530

Diagnosed with stage 4 non-Hodgkin’s lymphoma in 2021, IPS officer Nidhin Valsan resurrected himself by competing the Ironman triathlon and writing his memoir because he hopes to be a good influence on other cancer patients


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Never asked people to pick up weapons: Tahir Hussain to court

By www.thehindu.com
Published On :: Sat, 09 Nov 2024 00:43:34 +0530


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2024 Pacificon Inspires Next Generation of Radio Amateurs

By www.arrl.org
Published On :: Thu, 24 Oct 2024 14:03:00 -0500


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Amazon is designed to spin like a flywheel: Brian Dumaine

By www.thehindubusinessline.com
Published On :: Mon, 06 Jul 2020 08:01:00 +0530

In Bezonomics, the Fortune jounralist explains how Jeff Bezos has shrewdly changed the way business is done in today’s world


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Into the life of a billionaire-philanthropist

By www.thehindubusinessline.com
Published On :: Sun, 22 Nov 2020 21:46:39 +0530

The book covers Wipro founder Azim Premji’s journey without pulling any punches


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A kaleidoscopic memoir

By www.thehindubusinessline.com
Published On :: Sun, 20 Jun 2021 20:49:24 +0530

An anecdote filled book records a life well travelled


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For people with aspirations

By www.thehindubusinessline.com
Published On :: Sun, 01 Aug 2021 20:34:11 +0530

A book that focuses on an oft neglected aspect — soft skills


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Booming Digital Stars: 11 Inspiring Journeys from India’s Creator Economy 

By www.thehindubusinessline.com
Published On :: Sat, 19 Mar 2022 15:26:08 +0530

Lessons from the exciting success stories of social media influencers


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Uncertain future in a sea of poppies

By www.thehindu.com
Published On :: Sat, 18 Nov 2023 00:48:00 +0530

Three districts in Madhya Pradesh and Rajasthan together contribute to 80% of India’s opium production. Already facing the problem of stagnant procurement rates and rising input prices, farmers are now angry with the Union government for opening opium production and processing to private players. A.M. Jigeesh talks to farmers in the Mewar region about their concerns


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‘Very sweet’ variety gives fresh hope to Pineapple farmers in Kerala

By www.thehindu.com
Published On :: Wed, 03 Jan 2024 21:44:16 +0530

Possibility for mechanised processing for value addition and export being studied


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CSDS-Lokniti 2024 pre-poll survey | Understanding perspectives: farmers’ protests raise divisive opinions

By www.thehindu.com
Published On :: Thu, 11 Apr 2024 05:12:00 +0530

The farmers’ protests have become a critical point of contention, sparking diverse opinions across the nation


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  • Lok Sabha Elections