We thank the organizers of our International Summit on Human Gene Editing for their thoughtful concluding statement and welcome their call for us to continue to lead a global discussion on issues related to human gene editing.

Infectious disease outbreaks that turn into epidemics or pandemics can kill millions of people and cause trillions of dollars of damage to economic activity, says a new report from the international, independent Commission on a Global Health Risk Framework for the Future.

The best indicator of whether a disabled adult who receives Social Security benefits is capable of managing his or her benefits is evidence of real-world performance of meeting his or her own basic needs, rather than an office-based assessment of financial competence, says a new report from the National Academies of Sciences, Engineering, and Medicine.

A new report from the National Academies of Sciences, Engineering, and Medicine that examines the regulations governing federally funded research recommends that Congress authorize and the president appoint an independent national commission to examine and update the ethical, legal, and institutional frameworks governing research involving human subjects.

Rising levels of noise in the ocean have been identified as a growing concern for the well-being of marine mammals, but other threats such as pollution, climate change, and prey depletion by fisheries may also harm marine mammals and influence their response to additional noise.

Clinical trials for genome editing of the human germline – adding, removing, or replacing DNA base pairs in gametes or early embryos – could be permitted in the future, but only for serious conditions under stringent oversight, says a new report from the National Academy of Sciences and the National Academy of Medicine.

The U.S. Environmental Protection Agency (EPA) carries out experiments in which volunteer participants agree to be intentionally exposed by inhalation to specific pollutants at restricted concentrations over short periods to obtain important information about the effects of outdoor air pollution on human health.

The end of a roadside guardrail must be designed so that it is not a hazard to occupants of a vehicle striking it and so that it absorbs energy in a crash and redirects the vehicle into a safe trajectory.

A new report by the National Academies of Sciences, Engineering, and Medicine proposes a strategy that the U.S. Environmental Protection Agency (EPA) should use to evaluate the evidence of adverse human health effects from low doses of exposure to chemicals that can disrupt the endocrine system.

New Report Outlines Research Agenda to Better Understand the Relationship Among Microbiomes, Indoor Environments, and Human Health

The number of patients in the U.S. awaiting organ transplantation outpaces the amount of transplants performed in the U.S., and many donated organs are not transplanted each year due to several factors, such as poor organ function, says a new report from the National Academies of Sciences, Engineering, and Medicine.

A comprehensive aviation safety system as envisioned by NASA would require integration of a wide range of systems and practices, including building an in-time aviation safety management system (IASMS) that could detect and mitigate high-priority safety issues as they emerge and before they become hazards, says a new report by the National Academies of Sciences, Engineering, and Medicine.

While legal abortions in the U.S. are safe, the likelihood that women will receive the type of abortion services that best meet their needs varies considerably depending on where they live, says a new report from the National Academies of Sciences, Engineering, and Medicine.

An emerging body of evidence suggests that integrating STEMM fields (science, technology, engineering, mathematics, and medicine) with the humanities and arts in higher education is associated with positive learning outcomes that may help students enter the workforce, live enriched lives, and become active and informed citizens, says a new report from the National Academies of Sciences, Engineering, and Medicine

An international, multidisciplinary organizing committee has been appointed to plan the Second International Summit on Human Genome Editing, which will take place Nov. 27-29 in Hong Kong.

Improved understanding of the coupled natural-human coastal system will help promote resilience of coastal communities and ecosystems under rapidly changing environmental conditions and support informed decision-making, says a new report from the National Academies of Sciences, Engineering, and Medicine.

A new report from the National Academies of Sciences, Engineering, and Medicine examines evidence on whether providing permanent supportive housing (PSH) – a combination of stable housing and supportive services -- to individuals who are experiencing homelessness improves their health.

For his pioneering role in national health policy and health services research, the National Academy of Medicine today announced Stuart Altman is the recipient of the 2018 Gustav O. Lienhard Award for Advancement of Health Care.

On the eve of the Second International Summit on Human Genome Editing, we were informed of the birth of twins in China whose embryonic genomes had been edited.

Carrie Lam, Hong Kong’s chief executive, welcomed hundreds of participants from around the world to the Second International Summit on Human Genome Editing, which began today.

In December 2015, the U.S. National Academy of Sciences and U.S. National Academy of Medicine, the Royal Society of the United Kingdom, and the Chinese Academy of Sciences hosted an international summit in Washington, D.C., to discuss scientific, ethical, and governance issues associated with human genome editing.

We thank the organizing committee of the Second International Summit on Human Genome Editing, held this week in Hong Kong, for planning an important and timely conference on a rapidly advancing area of science and medicine.

A new publication from the U.S. National Academies of Sciences, Engineering, and Medicine, provides a brief summary of presentations and discussions at the Second International Summit on Human Genome Editing, held in Hong Kong on Nov. 27-29, 2018.

A new report from the National Academies of Sciences, Engineering, and Medicine offers guidance to the U.S. Environmental Protection Agency to inform the next revision of a permit program that requires industries to manage stormwater to minimize discharges of pollutants to the environment.

The Gulf Research Program (GRP) of the National Academies of Sciences, Engineering, and Medicine today announced a new funding opportunity under its Healthy Ecosystems Initiative.

A new report from the National Academies of Sciences, Engineering, and Medicine examines the effects and efficacy of using dispersants in marine oil spill response.

An international commission has been convened by the U.S. National Academy of Medicine, the U.S. National Academy of Sciences, and the Royal Society of the U.K., with the participation of science and medical academies around the world, to develop a framework for scientists, clinicians, and regulatory authorities to consider when assessing potential clinical applications of human germline genome editing.

The International Commission on the Clinical Use of Human Germline Genome Editing is tasked with identifying the scientific, medical, and ethical requirements to consider when assessing potential clinical applications of human germline genome editing — if society concludes that heritable human genome editing applications are acceptable.

In just a few years, digital technologies have allowed faster mobilization in response to humanitarian crises, better documentation of war crimes in conflict zones like Syria and Yemen, and more accessible platforms for organizing peaceful demonstrations around the world.

We recently launched a new website intended to highlight the science underlying questions that our research shows Americans have about current issues.

When Sara Altschule took a 23andMe ancestry test, the results confirmed what she already suspected - She is 77 percent Ashkenazi Jewish.

It has been a little over a year since the Second International Summit on Human Genome Editing in Hong Kong, where scientist He Jiankui (pictured above) announced the birth of twins whose healthy embryonic genomes had been edited to confer resistance to HIV.

A new report from the National Academies of Sciences, Engineering, and Medicine finds K-12 teachers face new expectations and more demands from policymakers, parents, students, and schools, including addressing changes in curriculum standards, the emergence of more explicit teaching goals, and shifts in what it means to support all students in their development.

In light of the present situation in the U.S., we believe that it is essential to explore a wide range of options for treating the increasing numbers of very ill patients with COVID-19 respiratory illness.

Pictured: Larry broadcasting AirTalk from the Mantle household for the first time last Friday.; Credit: Larry Mantle/KPCC

Dear KPCC Listener,

I hope you and your family are staying safe and healthy during this pandemic. We’re doing well at the Mantle house, but with Kristen and our son Desmond working and studying at home, we’re experiencing some of the same daily logistical challenges you likely are. With that in mind, I’d like to update you on the dramatic changes that have occurred with AirTalk during this time of COVID-19.

Every day a noted medical expert is joining us to answer listener questions. It’s allowed us to stay on the cutting edge of COVID-19 and public health developments.

We’re also continuing to convene the largest conversation anywhere in Southern California, but with a new focus. Each day listeners are describing how they’re dealing with the coronavirus, whether staying at home or providing essential services to our community. We’ve heard from students studying online, truck drivers looking for open restrooms on the highway, restaurant owners and employees wondering when, or if, they’ll be able to reopen, and listeners living in their cars seeking a hotel room or shower. In 35 years of hosting AirTalk, I’ve never experienced a time of greater importance for bringing Angelenos together. It’s vital that we talk with - and hear from - each other as we meet this experience together.

This wasn’t how I’d anticipated the 35th anniversary month of AirTalk, but I’m deeply appreciative of the work our dedicated producers are doing while they work from home. A prime example came last week when a hospital emergency forced our physician guest to cancel shortly before airtime. Our producers leapt to action, quickly finding noted infectious disease specialist Dr. Peter Chin-Hong to step right in.

When we finished the live segment, I thanked Dr. Chin-Hong for dropping his important work at UCSF Medical Center to join us. He replied that it’s always a pleasure to speak to one of his favorite audiences.

I couldn’t agree more. KPCC listeners are deeply devoted, not just to their favorite programs, but to the irreplaceable mission of KPCC. We’ll do everything we can during this difficult time to serve that mission – by serving you. Thank you for giving us that opportunity.

Sincerely,
Larry Mantle
Host, AirTalk

P.S. KPCC has always been funded by listeners, and member support is truly critical at this time. With recent substantial losses of sponsor support related to the pandemic, every donation makes a tremendous impact for this vital public service. If you can, please make a gift today to sustain the journalism you and your community needs.

This content is from Southern California Public Radio. View the original story at SCPR.org.

The Getty spent $65m (and change) for this late Manet masterpiece, "Spring."

A  132-year-old vision of springtime has landed permanently at the Getty Museum, smack in the middle of this California autumn: "Spring (Jeanne Demarsy)," one of Impressionist painter Edouard Manet’s  last completed pictures.

Here's what Getty Director Timothy Potts had to say about the artist:

Manet was the ultimate painter’s painter: totally committed to his craft, solidly grounded in the history of painting and yet determined to carve out a new path for himself and for modern art. ... Alone of his contemporaries (the only one who comes near is Degas), Manet achieved this almost impossible balancing act, absorbing and channeling the achievements of the past into a radically new vision of what painting could be.

"Spring" somehow manages to be the evocation of youth itself and all its hopes. The subject is 16-year-old actress Jeanne Demarsy, just then seeing her stage career ascend at the same time Manet neared the end of his own career. (He died at age 51 in 1883,  soon after the painting went on display.) 

For most of the years since its creation, the picture has been in private hands. It was recently on loan to the National Gallery.

Getty Assistant Curator Scott Allan said that the Getty worked hard to acquire "Spring" and was lucky to get her. According to news reports, the Christie's auction price paid was an eyebrow-lifting $65 million — about double the top previous sale price for a Manet. "We don’t discuss the price," Potts said.

At the Getty, "Spring (Jeanne Demarsy)" hangs next to an early Manet in the museum's Impressionist-Post Impressionist gallery. It was intended to be one of the "Four Seasons" by the late-19th century French master. The series was never completed (although "Autumn" hangs in a museum in France).

(More seasoning: Manet's "Autumn." Museum of Fine Arts of Nancy, France)

Allan said that, unlike many of Manet's early works, "Spring" was intended to hang in the Salon, the French art establishment’s showplace of traditional painting, which had rejected innovators like the Impressionists for decades. That led most of the Impressionists to disdain the Salon. But Allan said Manet was extremely pleased that his late work was accepted there. 

Here's Potts again:

So popular was it that "Spring" became the subject of one of the first color photographs of a work of art. Its acquisition by the Getty brings to Los Angeles the most important — and beautiful! — painting by this artist left in private hands and one of the great masterpieces of late-19th-century art. 

The painting depicts a lovely teenager, dressed in the peak of 1880s fashion in a blue-on-white printed dress; a flowered, fringed hat; and a parasol balanced on her left shoulder. The background features white rhododendrons, barely in blossom.

Mlle. Demarsy stares off to the left, the demure image of a confident young woman at the earliest spring of her adulthood, with an entire creative life before her, already immortalized before the world by one of the century’s greatest artists.

But Manet was himself at the peak of his accomplishments,  just before his sudden demise.
 
"Spring" became one of Manet’s most popular works, deeply appreciated by art lovers young and old and by critics of both the old guard and the avant garde. It was his last picture to hang in the Salon. Manet’s powers would soon decline, and he devoted much of his last few months to watercolors, said Allan.

(Getty director Timothy Potts looks at the Getty's new painting, Manet's "Spring." Getty Museum)

This content is from Southern California Public Radio. View the original story at SCPR.org.

At the corner of Glendale and Glenfeliz, Jeff Harmes created an art garden completely from scratch. ; Credit: Alana Rinicella

On the median on the Atwater Village side of the Hyperion bridge, Jeff Harmes built a garden. It's an act he calls "taking nothing and making it into something that everyone can get something out of, that can inspire everyone."

Having lived on the streets for 30 years, Jeff says grew to hate litter. He used to sweep street gutters with a piece of cardboard and remove trash packed into the forks of trees. He thought of them as small acts that would go mostly unnoticed.

On a whim last spring, he started tilling the median — or "the island," as he likes to call it ... although "oasis" is more like it, now. He made rock sculptures from stones he scrounged out of the L.A. River. In celebration of spring, he made a peace sign out of flowers. 

He says he doesn't know much about gardening or landscaping. He learns as he goes and looks to commuters for suggestions. In the absence of running water, he relies on rainfall.

Vibrant succulents sit next to kitschy items like gnomes and plastic flamingos. Intricate formations of seashells and stones contrast starkly against the neatly patted dirt. A young girl even donated her seashell collection for the peace sign. 

Recently, though, a vandal smashed the peace sign and wrecked Jeff's plants, including his squash crop. With help from the neighborhood, Jeff has been able to rebuild the garden. New plants have sprouted and the stonework has been repaired.

Jeff says his new goal with the garden is for people to draw something positive from it. "I want hate to be transferred into something beautiful," he said. Moving forward, he hopes to expand it down the island. 

(Note: This post has been edited. The original called it a "meridian," which is an invisible geographic line. "Median" is correct.)

This content is from Southern California Public Radio. View the original story at SCPR.org.

A decade-by-decade display of how many active gas storage wells are still in use by Southern California Gas Company. Source: Division of Oil, Gas and Geothermal Resources and SoCalGas; Credit: Aaron Mendelson/KPCC

The Aliso Canyon gas leak broke out near Porter Ranch nearly four years ago. On Tuesday a City Councilman called for an investigation of a different underground gas field after troubling images surfaced on video. 

The video uses a special infrared camera to show a duck swimming in the Ballona Wetlands amid bubbles of gas. An environmental advocacy group, Food and Water Watch, says the gas is methane.  They released the video this week to push for the city to investigate the underground gas storage field in nearby Playa del Rey.

Southern California Gas Co. says the gas surfacing in the wetlands is naturally occurring and unrelated to its underground natural gas storage field in Playa del Rey.

This content is from Southern California Public Radio. View the original story at SCPR.org.

; Credit: Courtesy Randy Newman

Read the full article at LAist

Alex Wolff in Human Capital.; Credit: Vertical Entertainment/Human Capital (2019)

Larry Mantle and KPCC film critics Lael Loewenstein, Claudia Puig and Tim Cogshell review this weekend’s new (streaming and VOD) movie releases.

• "Human Capital" on DirecTV

• "Crip Camp" on Netflix

• "The Platform" on Netflix

• "Blow The Man Down" on Amazon Prime Video

• "Phoenix, Oregon" on film's website

• "The Dog Doc" on Amazon Prime Video

• "Hooking Up" on Xfinity OnDemand

​CORRECTION: The film Human Capital is available on all on-demand platforms as of March 20th.

Guests:

Claudia Puig, film critic for KPCC and president of the Los Angeles Film Critics Association (LAFCA); she tweets @ClaudiaPuig

Lael Loewenstein, KPCC film critic and film columnist for the Santa Monica Daily Press; she tweets @LAELLO

Tim Cogshell, film critic for KPCC, Alt-Film Guide and CineGods.com; he tweets @CinemaInMind

This content is from Southern California Public Radio. View the original story at SCPR.org.

Director Eliza Hittman on the set of her film "Never Rarely Sometimes Always".
; Credit: Focus Features/Never Rarely Sometimes Always (2020)

The film “Never Rarely Sometimes Always” was slated for a theatrical release in March, but due to COVID-19 screenings were postponed. Instead, the film is out on digital this week, currently sporting a 98 percent rating on Rotten Tomatoes and receiving critical acclaim both here on FilmWeek and nationwide as one of the best films of 2020 so far.

Writer-director Eliza Hittman’s third feature-length film is about two teenage girls Skylar (Talia Ryder) and Autumn (Sidney Flanagan) from rural Pennsylvania who travel to New York City for medical help after an unplanned pregnancy. Hittman says the idea for the film came to her when she read in a book about how some women in Ireland, which up until recently had very strict laws against abortions, would travel from Ireland to London in 24 hours just to get a procedure. It struck her as worthy of a screenplay, and the idea was born. As part of her research for the film Hittman went to a small coal-mining community in rural Pennsylvania and, even though she wasn’t pregnant, visited pregnancy centers, got tested, and talked with women getting treatment and counseling so she could, as she says, “write the scenes with credibility.”

Today on FilmWeek, we’ll air “The Frame” host John Horn’s interview with “Never Rarely Sometimes Always” director Eliza Hittman where the two discuss how Hittman came up with the idea for the film, her journey to rural America to find out what visiting pregnancy centers there is like, and how that informed the way she conceived and wrote the film.

Guest:

Eliza Hittman, writer and director of “Never Rarely Sometimes Always”

This content is from Southern California Public Radio. View the original story at SCPR.org.

'California Mountain Lions,' Episode 7: Human Interaction

Larry Ellison, CEO of Oracle Corporation, gestures as he makes a speech during the New Economy Summit 2014 in this file photo taken in Tokyo on April 9, 2014. The company said Thursday, September 18, 2014, that Ellison would step aside as CEO and become chairman and chief technology officer.; Credit: TORU YAMANAKA/AFP/Getty Images

Oracle says Larry Ellison is stepping aside as CEO of the company he founded. The business software maker promoted Safra Catz and Mark Hurd to replace him as co-CEOs.

Ellison will reclaim the title of chairman at Oracle and is also taking the role of chief technology officer. Oracle says Ellison wants to focus on product engineering, technology development and strategy. Jeff Henley, Oracle's chairman since January 2004, is now its vice chairman.

Catz and Hurd were co-presidents of the Redwood Shores, California, company. Catz will be in charge of the company's manufacturing, finance and legal functions. Hurd will be in charge of sales, service, and other global business units.

Ellison founded Oracle Corp. in 1977 and was its chairman from May 1995 to January 2004.