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A Kernel Regression Procedure in the 3D Shape Space with an Application to Online Sales of Children’s Wear

Gregorio Quintana-Ortí, Amelia Simó.

Source: Statistical Science, Volume 34, Number 2, 236--252.

Abstract:
This paper is focused on kernel regression when the response variable is the shape of a 3D object represented by a configuration matrix of landmarks. Regression methods on this shape space are not trivial because this space has a complex finite-dimensional Riemannian manifold structure (non-Euclidean). Papers about it are scarce in the literature, the majority of them are restricted to the case of a single explanatory variable, and many of them are based on the approximated tangent space. In this paper, there are several methodological innovations. The first one is the adaptation of the general method for kernel regression analysis in manifold-valued data to the three-dimensional case of Kendall’s shape space. The second one is its generalization to the multivariate case and the addressing of the curse-of-dimensionality problem. Finally, we propose bootstrap confidence intervals for prediction. A simulation study is carried out to check the goodness of the procedure, and a comparison with a current approach is performed. Then, it is applied to a 3D database obtained from an anthropometric survey of the Spanish child population with a potential application to online sales of children’s wear.




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Comment: Variational Autoencoders as Empirical Bayes

Yixin Wang, Andrew C. Miller, David M. Blei.

Source: Statistical Science, Volume 34, Number 2, 229--233.




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Comment: Empirical Bayes Interval Estimation

Wenhua Jiang.

Source: Statistical Science, Volume 34, Number 2, 219--223.

Abstract:
This is a contribution to the discussion of the enlightening paper by Professor Efron. We focus on empirical Bayes interval estimation. We discuss the oracle interval estimation rules, the empirical Bayes estimation of the oracle rule and the computation. Some numerical results are reported.




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A Conversation with Dick Dudley

Vladimir Koltchinskii, Richard Nickl, Philippe Rigollet.

Source: Statistical Science, Volume 34, Number 1, 169--175.

Abstract:
Richard Mansfield Dudley (Dick Dudley) was born in 1938. He received the A.B. from Harvard in 1952 and the Ph.D. from Princeton in 1962 (under the supervision of Gilbert Hunt and Edward Nelson). Following an appointment at UC Berkeley as an assistant professor, he joined the Department of Mathematics at MIT in 1967. Dick Dudley has made fundamental contributions to the theory of Gaussian processes and Probability in Banach Spaces. Among his major achievements is the development of a general framework for empirical processes theory, in particular, for uniform central limit theorems. These results have had and continue having tremendous impact in contemporary statistics and in mathematical foundations of machine learning. A more extensive biographical sketch is contained in the preface to the Selected works of R. M. Dudley (editors: E. Giné, V. Koltchinskii and R. Norvaisa) published in 2010. This conversation took place (mostly, via email) in the fall of 2017.




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A Conversation with Piet Groeneboom

Geurt Jongbloed.

Source: Statistical Science, Volume 34, Number 1, 156--168.

Abstract:
Petrus (Piet) Groeneboom was born in Scheveningen in 1941 and grew up in Voorburg. Both villages are located near The Hague in The Netherlands; Scheveningen actually being part of The Hague. He attended the gymnasium of the Huygens lyceum. In 1959, he entered the University of Amsterdam, where he studied psychology. After his “candidate” exam (comparable to BSc) in 1963, he worked at the psychological laboratory of the University of Amsterdam until 1966. In 1965, he took up mathematics as a part-time study. After having obtained his master’s degree in 1971, he had a position at the psychological laboratory again until 1973, when he was appointed to the Mathematical Center in Amsterdam. There, he wrote between 1975 and 1979 his Ph.D. thesis with Kobus Oosterhoff as advisor, graduating in 1979. After a period of two years as visiting professor at the University of Washington (UW) in Seattle, Piet moved back to the Mathematical Center until he was appointed full professor of statistics at the University of Amsterdam in 1984. Four years later, he moved to Delft University of Technology where he became professor of statistics and stayed until his retirement in 2006. Between 2000 and 2006 he also held a part-time professorship at the Vrije Universiteit in Amsterdam. From 1999 till 2013 he was Affiliate Professor at the statistics department of UW, Seattle. Apart from being visiting professor at the UW in Seattle, he was also visiting professor at Stanford University, Université Paris 6 and ETH Zürich. Piet is well known for his work on shape constrained statistical inference. He worked on asymptotic theory for these problems, created algorithms to compute nonparametric estimates in such models and applied these models to real data. He also worked on interacting particle systems, extreme value analysis and efficiency theory for testing procedures. Piet (co-)authored four books and 64 papers and served as promotor of 13 students. He is the recipient of the 1985 Rollo Davidson prize, a fellow of the IMS and elected member of the ISI. In 2015, he delivered the Wald lecture at the Joint Statistical Meeting in Montreal. Piet and his wife Marijke live in Naarden. He has two sons, Thomas and Tim, and (since June 12, 2018) one grandson, Tarik. This conversation was held at Piet’s house in Naarden, on February 28 and April 24, 2018.




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Gaussian Integrals and Rice Series in Crossing Distributions—to Compute the Distribution of Maxima and Other Features of Gaussian Processes

Georg Lindgren.

Source: Statistical Science, Volume 34, Number 1, 100--128.

Abstract:
We describe and compare how methods based on the classical Rice’s formula for the expected number, and higher moments, of level crossings by a Gaussian process stand up to contemporary numerical methods to accurately deal with crossing related characteristics of the sample paths. We illustrate the relative merits in accuracy and computing time of the Rice moment methods and the exact numerical method, developed since the late 1990s, on three groups of distribution problems, the maximum over a finite interval and the waiting time to first crossing, the length of excursions over a level, and the joint period/amplitude of oscillations. We also treat the notoriously difficult problem of dependence between successive zero crossing distances. The exact solution has been known since at least 2000, but it has remained largely unnoticed outside the ocean science community. Extensive simulation studies illustrate the accuracy of the numerical methods. As a historical introduction an attempt is made to illustrate the relation between Rice’s original formulation and arguments and the exact numerical methods.




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Comment: Contributions of Model Features to BART Causal Inference Performance Using ACIC 2016 Competition Data

Nicole Bohme Carnegie.

Source: Statistical Science, Volume 34, Number 1, 90--93.

Abstract:
With a thorough exposition of the methods and results of the 2016 Atlantic Causal Inference Competition, Dorie et al. have set a new standard for reproducibility and comparability of evaluations of causal inference methods. In particular, the open-source R package aciccomp2016, which permits reproduction of all datasets used in the competition, will be an invaluable resource for evaluation of future methodological developments. Building upon results from Dorie et al., we examine whether a set of potential modifications to Bayesian Additive Regression Trees (BART)—multiple chains in model fitting, using the propensity score as a covariate, targeted maximum likelihood estimation (TMLE), and computing symmetric confidence intervals—have a stronger impact on bias, RMSE, and confidence interval coverage in combination than they do alone. We find that bias in the estimate of SATT is minimal, regardless of the BART formulation. For purposes of CI coverage, however, all proposed modifications are beneficial—alone and in combination—but use of TMLE is least beneficial for coverage and results in considerably wider confidence intervals.




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Comment on “Automated Versus Do-It-Yourself Methods for Causal Inference: Lessons Learned from a Data Analysis Competition”

Susan Gruber, Mark J. van der Laan.

Source: Statistical Science, Volume 34, Number 1, 82--85.

Abstract:
Dorie and co-authors (DHSSC) are to be congratulated for initiating the ACIC Data Challenge. Their project engaged the community and accelerated research by providing a level playing field for comparing the performance of a priori specified algorithms. DHSSC identified themes concerning characteristics of the DGP, properties of the estimators, and inference. We discuss these themes in the context of targeted learning.




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Matching Methods for Causal Inference: A Review and a Look Forward

Elizabeth A. Stuart

Source: Statist. Sci., Volume 25, Number 1, 1--21.

Abstract:
When estimating causal effects using observational data, it is desirable to replicate a randomized experiment as closely as possible by obtaining treated and control groups with similar covariate distributions. This goal can often be achieved by choosing well-matched samples of the original treated and control groups, thereby reducing bias due to the covariates. Since the 1970s, work on matching methods has examined how to best choose treated and control subjects for comparison. Matching methods are gaining popularity in fields such as economics, epidemiology, medicine and political science. However, until now the literature and related advice has been scattered across disciplines. Researchers who are interested in using matching methods—or developing methods related to matching—do not have a single place to turn to learn about past and current research. This paper provides a structure for thinking about matching methods and guidance on their use, coalescing the existing research (both old and new) and providing a summary of where the literature on matching methods is now and where it should be headed.




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Heteromodal Cortical Areas Encode Sensory-Motor Features of Word Meaning

The capacity to process information in conceptual form is a fundamental aspect of human cognition, yet little is known about how this type of information is encoded in the brain. Although the role of sensory and motor cortical areas has been a focus of recent debate, neuroimaging studies of concept representation consistently implicate a network of heteromodal areas that seem to support concept retrieval in general rather than knowledge related to any particular sensory-motor content. We used predictive machine learning on fMRI data to investigate the hypothesis that cortical areas in this "general semantic network" (GSN) encode multimodal information derived from basic sensory-motor processes, possibly functioning as convergence–divergence zones for distributed concept representation. An encoding model based on five conceptual attributes directly related to sensory-motor experience (sound, color, shape, manipulability, and visual motion) was used to predict brain activation patterns associated with individual lexical concepts in a semantic decision task. When the analysis was restricted to voxels in the GSN, the model was able to identify the activation patterns corresponding to individual concrete concepts significantly above chance. In contrast, a model based on five perceptual attributes of the word form performed at chance level. This pattern was reversed when the analysis was restricted to areas involved in the perceptual analysis of written word forms. These results indicate that heteromodal areas involved in semantic processing encode information about the relative importance of different sensory-motor attributes of concepts, possibly by storing particular combinations of sensory and motor features.

SIGNIFICANCE STATEMENT The present study used a predictive encoding model of word semantics to decode conceptual information from neural activity in heteromodal cortical areas. The model is based on five sensory-motor attributes of word meaning (color, shape, sound, visual motion, and manipulability) and encodes the relative importance of each attribute to the meaning of a word. This is the first demonstration that heteromodal areas involved in semantic processing can discriminate between different concepts based on sensory-motor information alone. This finding indicates that the brain represents concepts as multimodal combinations of sensory and motor representations.




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No smoking no hate / Biman Mullick.

London : Cleanair, Smoke-free Environment (33 Stillness Rd, London, SE23 1NG), [198-?]




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Heat burn. / design : Biman Mullick.

London : Cleanair (33 Stillness Rd, London, SE23 1NG), [198-?]




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Cleanair posters to create a smoke-free environment / designed by Biman Mullick ; published by Cleanair.

London (33 Stillness Road, London SE23 ING) : Cleanair, [198-?]




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[Silhouette of a pregant woman smoking with death skull inside womb, 29 January 1994] / design: Biman Mullick.

London, [29 January 1994]




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Danny Smith from No Human Being Is Illegal (in all our glory). Collaged photograph by Deborah Kelly and collaborators, 2014-2018.

[London], 2019.




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Jennifer Lopez Is Wearing the Hell Out of These $60 Sneakers—and You Can Buy Them at Zappos

The chic sneaks are part of Zappos' massive Cyber Monday sale.




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Katie Holmes’s Affordable Sneakers Are the Star of Her Latest Outfit

Meghan Markle is also a fan of the comfy shoes.




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The Comfy Sneakers That Kate Middleton, Kelly Ripa, and More Celebs Love Are on Sale at Amazon

Keep your feet comfy and your wallet fat.




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Forget Black Booties, Amal Clooney and J.Lo Are Wearing This Weather-Resistant Boot Trend Instead

And it’s on sale at Nordstrom.




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Sweatsuits Should Be Your Cozy Day Uniform—and These Are Our Favorites From Amazon

This retro style is making a comeback for a reason.




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Of Course Katie Holmes Found This Year’s Coziest Winter Boot

Keep your feet happy this winter.




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Shoppers Swear These $30 Colorfulkoala Leggings Are the Ultimate Lululemon Dupes

And they’re available in 19 fun prints.




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The Axon Initial Segment: An Updated Viewpoint

Christophe Leterrier
Feb 28, 2018; 38:2135-2145
Viewpoints




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Allometric Analysis Detects Brain Size-Independent Effects of Sex and Sex Chromosome Complement on Human Cerebellar Organization

Catherine Mankiw
May 24, 2017; 37:5221-5231
Development Plasticity Repair




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Multisensory Integration and the Society for Neuroscience: Then and Now

Barry E. Stein
Jan 2, 2020; 40:3-11
Viewpoints




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Optimization of a GCaMP Calcium Indicator for Neural Activity Imaging

Jasper Akerboom
Oct 3, 2012; 32:13819-13840
Cellular




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The Cognitive Thalamus as a Gateway to Mental Representations

Mathieu Wolff
Jan 2, 2019; 39:3-14
Viewpoints




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Physical Exercise Prevents Stress-Induced Activation of Granule Neurons and Enhances Local Inhibitory Mechanisms in the Dentate Gyrus

Timothy J. Schoenfeld
May 1, 2013; 33:7770-7777
BehavioralSystemsCognitive




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Sleep Deprivation Biases the Neural Mechanisms Underlying Economic Preferences

Vinod Venkatraman
Mar 9, 2011; 31:3712-3718
BehavioralSystemsCognitive




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Axonal ramifications of hippocampal Ca1 pyramidal cells

WD Knowles
Nov 1, 1981; 1:1236-1241
Articles




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The Pain of Sleep Loss: A Brain Characterization in Humans

Adam J. Krause
Mar 20, 2019; 39:2291-2300
BehavioralSystemsCognitive




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{Delta}9-Tetrahydrocannabinol and Cannabinol Activate Capsaicin-Sensitive Sensory Nerves via a CB1 and CB2 Cannabinoid Receptor-Independent Mechanism

Peter M. Zygmunt
Jun 1, 2002; 22:4720-4727
Behavioral




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Afferents and Homotypic Neighbors Regulate Horizontal Cell Morphology, Connectivity, and Retinal Coverage

Benjamin E. Reese
Mar 2, 2005; 25:2167-2175
BehavioralSystemsCognitive




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Synaptic Specificity and Application of Anterograde Transsynaptic AAV for Probing Neural Circuitry

Brian Zingg
Apr 15, 2020; 40:3250-3267
Systems/Circuits




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Nurture versus Nature: Long-Term Impact of Forced Right-Handedness on Structure of Pericentral Cortex and Basal Ganglia

Stefan Klöppel
Mar 3, 2010; 30:3271-3275
BRIEF COMMUNICATION




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The Representation of Semantic Information Across Human Cerebral Cortex During Listening Versus Reading Is Invariant to Stimulus Modality

Fatma Deniz
Sep 25, 2019; 39:7722-7736
BehavioralSystemsCognitive




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Astrocytes Modulate Baroreflex Sensitivity at the Level of the Nucleus of the Solitary Tract

Svetlana Mastitskaya
Apr 8, 2020; 40:3052-3062
Systems/Circuits




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Daily Marijuana Use Is Not Associated with Brain Morphometric Measures in Adolescents or Adults

Barbara J. Weiland
Jan 28, 2015; 35:1505-1512
Neurobiology of Disease




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The Effect of Body Posture on Brain Glymphatic Transport

Hedok Lee
Aug 5, 2015; 35:11034-11044
Neurobiology of Disease




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Fingolimod Rescues Demyelination in a Mouse Model of Krabbe's Disease

Sibylle Béchet
Apr 8, 2020; 40:3104-3118
Neurobiology of Disease




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Dural Calcitonin Gene-Related Peptide Produces Female-Specific Responses in Rodent Migraine Models

Amanda Avona
May 29, 2019; 39:4323-4331
Systems/Circuits




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Circuit Stability to Perturbations Reveals Hidden Variability in the Balance of Intrinsic and Synaptic Conductances

Sebastian Onasch
Apr 15, 2020; 40:3186-3202
Systems/Circuits




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Significant Neuroanatomical Variation Among Domestic Dog Breeds

Erin E. Hecht
Sep 25, 2019; 39:7748-7758
BehavioralSystemsCognitive




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Where Is the Anterior Temporal Lobe and What Does It Do?

Michael F. Bonner
Mar 6, 2013; 33:4213-4215
Journal Club




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White Matter Microstructure in Transsexuals and Controls Investigated by Diffusion Tensor Imaging

Georg S. Kranz
Nov 12, 2014; 34:15466-15475
Systems/Circuits




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A Transcriptome Database for Astrocytes, Neurons, and Oligodendrocytes: A New Resource for Understanding Brain Development and Function

John D. Cahoy
Jan 2, 2008; 28:264-278
Cellular




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Grey Matter Volume Differences Associated with Extremely Low Levels of Cannabis Use in Adolescence

Catherine Orr
Mar 6, 2019; 39:1817-1827
BehavioralSystemsCognitive




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What Visual Information Is Processed in the Human Dorsal Stream?

Martin N. Hebart
Jun 13, 2012; 32:8107-8109
Journal Club




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Nasal Respiration Entrains Human Limbic Oscillations and Modulates Cognitive Function

Christina Zelano
Dec 7, 2016; 36:12448-12467
Systems/Circuits




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An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

Ye Zhang
Sep 3, 2014; 34:11929-11947
Cellular