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Feasibility, Tolerability, and Preliminary Clinical Response of Fractionated Radiopharmaceutical Therapy with 213Bi-FAPI-46: Pilot Experience in Patients with End-Stage, Progressive Metastatic Tumors

Visual Abstract




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Performance Characteristics of a New Generation 148-cm Axial Field-of-View uMI Panorama GS PET/CT System with Extended NEMA NU 2-2018 and EARL Standards

Visual Abstract




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SPECT/CT in Early Response Assessment of Patients with Metastatic Castration-Resistant Prostate Cancer Receiving 177Lu-PSMA-617

Visual Abstract




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CD70-Targeted Immuno-PET/CT Imaging of Clear Cell Renal Cell Carcinoma: A Translational Study

Visual Abstract




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Feasibility of 177Lu-PSMA Administration as Outpatient Procedure for Prostate Cancer




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International Metabolic Prognostic Index Is Superior to Other Metabolic Tumor Volume-Based Prognostication Methods in a Real-Life Cohort of Diffuse Large B-Cell Lymphoma

Visual Abstract




o

Changed Regulation Enables Pragmatic Solution for Cancer Patients




o

SophosAI team presents three papers on AI applied to cybersecurity at CAMLIS

On October 24 and 25, SophosAI presents ideas on how to use models large and small—and defend against malignant ones.




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Sophos Firewall hardening best practices

Make the most of your Sophos Firewall.




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Pacific Rim timeline: Information for defenders from a braid of interlocking attack campaigns

Sophos X-Ops unveils five-year investigation tracking China-based groups targeting perimeter devices




o

Digital Detritus: The engine of Pacific Rim and a call to the industry for action

Decades of obsolete and unpatched hardware and software endanger us all




o

Pacific Rim: Learning to eat soup with a knife

What our incident responders know from five years of fighting an octopus




o

Pacific Rim: What’s it to you?

Thirty-five years after the first great cat-and-mouse infosecurity story, here we are again




o

From the frontlines: Our CISO’s view of Pacific Rim

On beyond “Detect and Respond” and “Secure by Design”






o

VEEAM exploit seen used again with a new ransomware: “Frag”

Last month, Sophos X-Ops reported several MDR cases where threat actors exploited a vulnerability in Veeam backup servers. We continue to track the activities of this threat cluster, which recently included deployment of a new ransomware. The vulnerability, CVE-2024-40711, was used as part of a threat activity cluster we named STAC 5881. Attacks leveraged compromised […]




o

Re: Voluntary assisted death: how to ensure access and safety




o

"Questioning the Quantifiable: Are We Measuring What Matters in Heart Failure Care?"




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Overdose crisis: more common sense and less ideology




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Addressing Climate Catastrophe Concerns in Asthma Medication Delivery: Rethinking Inhaler Use for Environmental and Clinical Efficacy




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Re: Scandal of “newborn gang” that put profits ahead of babies’ lives rocks Turkey’s health system




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Re: Scandal of “newborn gang” that put profits ahead of babies’ lives rocks Turkey’s health system




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Re: Scandal of “newborn gang” that put profits ahead of babies’ lives rocks Turkey’s health system




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Re: Scandal of “newborn gang” that put profits ahead of babies’ lives rocks Turkey’s health system




o

Re: Decompression alone or with fusion for degenerative lumbar spondylolisthesis (Nordsten-DS): five year follow-up of a randomised, multicentre, non-inferiority trial




o

A Comprehensive Gender-related Secretome of Plasmodium berghei Sexual Stages

Felicia Grasso
Dec 1, 2020; 19:1986-1996
Research




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Citrus Vascular Proteomics Highlights the Role of Peroxidases and Serine Proteases during Huanglongbing Disease Progression

Jessica Y. Franco
Dec 1, 2020; 19:1936-1951
Research




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Global lysine acetylation and 2-hydroxyisobutyrylation reveal the metabolism conversion mechanism in Giardia lamblia

Wenhe Zhu
Dec 29, 2020; 0:RA120.002353v1-mcp.RA120.002353
Research




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Novel Proteomic Profiling of Epididymal Extracellular Vesicles in the Domestic Cat Reveals Proteins Related to Sequential Sperm Maturation with Differences Observed between Normospermic and Teratospermic Individuals

Tricia Rowlison
Dec 1, 2020; 19:2090-2103
Research




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Separation and identification of permethylated glycan isomers by reversed phase nanoLC-NSI-MS

Simone Kurz
Dec 29, 2020; 0:RA120.002266v1-mcp.RA120.002266
Research




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High-throughput and site-specific N-glycosylation analysis of human alpha-1-acid glycoprotein offers a great potential for new biomarker discovery

Toma Keser
Dec 29, 2020; 0:RA120.002433v1-mcp.RA120.002433
Research




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Stoichiometry of Nucleotide Binding to Proteasome AAA+ ATPase Hexamer Established by Native Mass Spectrometry

Yadong Yu
Dec 1, 2020; 19:1997-2014
Research




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Identification of novel serological autoantibodies in Takayasu arteritis patients using HuProt arrays

Xiao-Ting Wen
Dec 17, 2020; 0:RA120.002119v1-mcp.RA120.002119
Research




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Interspecies differences in proteome turnover kinetics are correlated with lifespans and energetic demands

Kyle Swovick
Dec 28, 2020; 0:RA120.002301v1-mcp.RA120.002301
Research




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Global Proteome and Phosphoproteome Characterization of Sepsis-induced Kidney Injury

Yi-Han Lin
Dec 1, 2020; 19:2030-2046
Research




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A Mouse Brain-based Multi-omics Integrative Approach Reveals Potential Blood Biomarkers for Ischemic Stroke

Alba Simats
Dec 1, 2020; 19:1921-1935
Research




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Multi-sample mass spectrometry-based approach for discovering injury markers in chronic kidney disease

Ji Eun Kim
Dec 20, 2020; 0:RA120.002159v1-mcp.RA120.002159
Research




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OpenPepXL: An Open-Source Tool for Sensitive Identification of Cross-Linked Peptides in XL-MS

Eugen Netz
Dec 1, 2020; 19:2157-2167
Technological Innovation and Resources




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Kinome Profiling of Primary Endometrial Tumors Using Multiplexed Inhibitor Beads and Mass Spectrometry Identifies SRPK1 as Candidate Therapeutic Target

Alison M. Kurimchak
Dec 1, 2020; 19:2068-2089
Research




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A Novel Mechanism for NF-{kappa}B-activation via I{kappa}B-aggregation: Implications for Hepatic Mallory-Denk-Body Induced Inflammation

Yi Liu
Dec 1, 2020; 19:1968-1985
Research




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The role of Data-Independent Acquisition for Glycoproteomics

Zilu Ye
Dec 28, 2020; 0:R120.002204v1-mcp.R120.002204
Review




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Temporal Quantitative Proteomics of mGluR-induced Protein Translation and Phosphorylation in Neurons

Charlotte A. G. H. van Gelder
Dec 1, 2020; 19:1952-1967
Research




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Proteome-wide Analysis Reveals Substrates of E3 Ligase RNF146 Targeted for Degradation

Litong Nie
Dec 1, 2020; 19:2015-2029
Research




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Identification of Microorganisms by Liquid Chromatography-Mass Spectrometry (LC-MS1) and in Silico Peptide Mass Libraries

Peter Lasch
Dec 1, 2020; 19:2125-2138
Technological Innovation and Resources




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Unraveling the MAX2 Protein Network in Arabidopsis thaliana: Identification of the Protein Phosphatase PAPP5 as a Novel MAX2 Interactor

Sylwia Struk
Dec 28, 2020; 0:RA119.001766v1-mcp.RA119.001766
Research




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CMMB (Carboxylate Modified Magnetic Bead) -based isopropanol gradient peptide fractionation (CIF) enables rapid and robust off-line peptide mixture fractionation in bottom-up proteomics

Weixian Deng
Dec 22, 2020; 0:RA120.002411v1-mcp.RA120.002411
Research




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Systematic identification of P. falciparum sporozoite membrane protein interactions reveals an essential role for the p24 complex in host infection

Julia Knöckel
Dec 22, 2020; 0:RA120.002432v1-mcp.RA120.002432
Research




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In depth characterization of the Staphylococcus aureus phosphoproteome reveals new targets of Stk1

Nadine Prust
Dec 17, 2020; 0:RA120.002232v1-mcp.RA120.002232
Research




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On the robustness of graph-based clustering to random network alterations

R. Greg Stacey
Nov 4, 2020; 0:RA120.002275v1-mcp.RA120.002275
Research