me [ASAP] Design and Characterization of the First Selective and Potent Mechanism-Based Inhibitor of Cytochrome P450 4Z1 By feedproxy.google.com Published On :: Thu, 30 Apr 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c00101 Full Article
me [ASAP] Degradation versus Inhibition: Development of Proteolysis-Targeting Chimeras for Overcoming Statin-Induced Compensatory Upregulation of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase By feedproxy.google.com Published On :: Mon, 04 May 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c00339 Full Article
me [ASAP] Targeting ALK2: An Open Science Approach to Developing Therapeutics for the Treatment of Diffuse Intrinsic Pontine Glioma By feedproxy.google.com Published On :: Tue, 05 May 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c00395 Full Article
me [ASAP] Discovery of Potent Inhibitors against P-Glycoprotein-Mediated Multidrug Resistance Aided by Late-Stage Functionalization of a 2-(4-(Pyridin-2-yl)phenoxy)pyridine Analogue By feedproxy.google.com Published On :: Thu, 07 May 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c00337 Full Article
me [ASAP] Discovery of <italic toggle="yes">N</italic>-Ethyl-4-[2-(4-fluoro-2,6-dimethyl-phenoxy)-5-(1-hydroxy-1-methyl-ethyl)phenyl]-6-methyl-7-oxo-1<italic toggle="yes">H</italic>-pyrrolo[2,3-<italic toggle=&q By feedproxy.google.com Published On :: Thu, 07 May 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c00628 Full Article
me [ASAP] Drug Research Meets Network Science: Where Are We? By feedproxy.google.com Published On :: Fri, 08 May 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.9b01989 Full Article
me [ASAP] Molecular Basis for Omapatrilat and Sampatrilat Binding to Neprilysin—Implications for Dual Inhibitor Design with Angiotensin-Converting Enzyme By feedproxy.google.com Published On :: Fri, 08 May 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c00441 Full Article
me [ASAP] Discovery of a Cyclic Choline Analog That Inhibits Anaerobic Choline Metabolism by Human Gut Bacteria By feedproxy.google.com Published On :: Mon, 30 Mar 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00005 Full Article
me [ASAP] Chimeric Peptidomimetics of SOCS 3 Able to Interact with JAK2 as Anti-inflammatory Compounds By feedproxy.google.com Published On :: Mon, 30 Mar 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.9b00664 Full Article
me [ASAP] Inhibitors of Hypoxia-Inducible Factors as Treatment for Cancer By feedproxy.google.com Published On :: Wed, 01 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00116 Full Article
me [ASAP] Glycans Meet Sphingolipids: Structure-Based Design of Glycan Containing Analogues of a Sphingosine Kinase Inhibitor By feedproxy.google.com Published On :: Wed, 01 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.9b00665 Full Article
me [ASAP] Design, Synthesis, and Pharmacological Evaluation of Second Generation EZH2 Inhibitors with Long Residence Time By feedproxy.google.com Published On :: Thu, 02 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00045 Full Article
me [ASAP] Escaping from Flatland: Substituted Bridged Pyrrolidine Fragments with Inherent Three-Dimensional Character By feedproxy.google.com Published On :: Thu, 02 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00039 Full Article
me [ASAP] Structure Optimization of Gatastatin for the Development of ?-Tubulin-Specific Inhibitor By feedproxy.google.com Published On :: Mon, 06 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.9b00526 Full Article
me [ASAP] Rationally Designed Covalent BCL6 Inhibitor That Targets a Tyrosine Residue in the Homodimer Interface By feedproxy.google.com Published On :: Tue, 07 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00111 Full Article
me [ASAP] New Dual CK2/HDAC1 Inhibitors with Nanomolar Inhibitory Activity against Both Enzymes By feedproxy.google.com Published On :: Fri, 10 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.9b00561 Full Article
me [ASAP] Potential Cancer Treatment by Agonists of the Stimulator of Interferon Genes By feedproxy.google.com Published On :: Mon, 13 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00117 Full Article
me [ASAP] Artemisinin Derivatives with Antimelanoma Activity Show Inhibitory Effect against Human DNA Topoisomerase 1 By feedproxy.google.com Published On :: Tue, 14 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00131 Full Article
me [ASAP] Discovery of an Atropisomeric PI3Kß Selective Inhibitor through Optimization of the Hinge Binding Motif By feedproxy.google.com Published On :: Wed, 15 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00095 Full Article
me [ASAP] PROTAC Compounds Targeting a-Synuclein Protein for Treating Neurogenerative Disorders: Alzheimer’s and Parkinson’s Diseases By feedproxy.google.com Published On :: Tue, 28 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00192 Full Article
me [ASAP] Development of Selective Steroid Inhibitors for the Glucose-6-phosphate Dehydrogenase from <italic toggle="yes">Trypanosoma cruzi</italic> By feedproxy.google.com Published On :: Wed, 29 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00106 Full Article
me [ASAP] Discovery of RO7185876, a Highly Potent ?-Secretase Modulator (GSM) as a Potential Treatment for Alzheimer’s Disease By feedproxy.google.com Published On :: Fri, 01 May 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00109 Full Article
me [ASAP] Ultra-High-Throughput Acoustic Droplet Ejection-Open Port Interface-Mass Spectrometry for Parallel Medicinal Chemistry By feedproxy.google.com Published On :: Fri, 01 May 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00066 Full Article
me [ASAP] Development of a Raltegravir-based Photoaffinity-Labeled Probe for Human Immunodeficiency Virus-1 Integrase Capture By feedproxy.google.com Published On :: Tue, 05 May 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00009 Full Article
me China’s New Large Solar-Powered Drone Reaches 20,000 Meters in Altitude By latestsolarnews.com Published On :: Tue, 06 Jun 2017 16:29:43 +0000 China’s first domestically designed large solar-powered unmanned plane reached above 20,000 meters in altitude on its test flight in the country’s northwest regions recently. The drone was developed by the China Academy of Aerospace Aerodynamics (CAAA), it’s developers kept the exact size of the drone as a secret, but it is believed to be about 14 … The post China’s New Large Solar-Powered Drone Reaches 20,000 Meters in Altitude appeared first on LatestSolarNews. Full Article News
me New Solar Plant In Chile To Power 13,000 Homes Per Year By latestsolarnews.com Published On :: Thu, 14 Dec 2017 01:36:55 +0000 Chile is building a brand new solar power plant that has some exciting outcome on the future. The plant is expected to provide energy on day and night as well as throughout inclement weather, to power up to 13,000 homes annually. This project will make Chile one of the top solar energy spots in the … The post New Solar Plant In Chile To Power 13,000 Homes Per Year appeared first on LatestSolarNews. Full Article solar news
me Spacing elements By simurai.com Published On :: Sun, 25 May 2014 00:00:00 +0000 So let’s say we have a “bar” with some items inside. Like a header or footer. Let’s also say we want those items to be spaced evenly, meaning they have the same gap everywhere. Shouldn’t be a big problem. Let’s take a look: 1. Margin We can’t just add margin: 2rem to the elements since there is no margin collapsing on the horizontal axis. And it also doesn’t work when using Flexbox. Leaving a double sized gap in between. Wishing there is something like margin: 2rem collapse; where you can enable/disable it optionally. See the Pen Spacing elements (no collapsing) by simurai (@simurai) on CodePen. 2. Pseudo classes Using margin: 2rem 0 2rem 2rem and then a pseudo class like :last-child { margin-right: 2rem } to add the extra margin works as long as you don’t need to hide that element with display: none. Maybe a rare case, but I’ve been running into this issue once in a while. Would be cool if there is something like :last-displayed that would ignore elements that have display:none. See the Pen Spacing elements (pseudo) by simurai (@simurai) on CodePen. 3. Margin + padding (best) The easiest way I think, is to add margins to all elements (like in the first example), but then also add the same value as padding to the parent element. Like this: .Header { padding: 1rem; } .Header-item { margin: 1rem; } That way all elements are evenly spaced and you still can use display:none without having to worry about breaking it. A little flaw is that you have to keep the 2 values in sync, but if you’re using a preprocessor, it can just be a single variable. Or maybe you could use REM’s to control it with font-size from the :root. See the Pen Spacing elements by simurai (@simurai) on CodePen. Other? There are more ways but I’m not aware of a simple one that also let’s you use display: none. Let me know otherwise. Maybe the Visual Format Language in GSS? Looks quite slick. Update A couple more options: Using Grandpa’s table, still need to test this Using calc() Using Adjacent selector More selector “hacks”: 1, 2 Hmmm.. gotta try some. I kinda like the 3rd one. Keeps it independent from the parent and is not “too” complicated. Full Article
me DuoTone themes By simurai.com Published On :: Fri, 01 Jan 2016 00:00:00 +0000 Double-hue syntax themes for Atom. DuoTone themes use only 2 hues (7 shades in total). It tones down less important parts (like punctuation and brackets) and highlights only the important ones. This leads to a more calm color scheme, but still lets you find the stuff you’re looking for. A big thanks goes to @braver who did most of the initial language support. Color variations And here some more color variations created by other theme authors. Full Article
me 17 Tools for Effective Customer Engagement By www.webdesignerdepot.com Published On :: Thu, 23 Apr 2020 10:45:09 +0000 The one thing that every business that offers a service has in common is its customers. It doesn't matter if you are a freelancer with just one client or a small design agency with a few clients, you have to deal with customers on a day to day basis. Full Article Tools & Resources client surveys customer feedback apps customer relations tools customer service apps customer surveys
me Email Personalization: Your Secret To Better Engagement By www.webdesignerdepot.com Published On :: Wed, 29 Apr 2020 10:45:54 +0000 One of the struggles that marketers face is how to send the right message at exactly the right time to target people in a way that will appeal to them. To solve the problem, businesses need to get themselves acquainted with new technologies and the power of personalization. In the past few years, digital marketing […] Full Article Search & Marketing customer funnel email engagement email marketing marketing tips personalized email
me 8 of the Top WP Multipurpose Themes That You Can Use By www.webdesignerdepot.com Published On :: Tue, 05 May 2020 10:45:00 +0000 More than a few multipurpose WordPress themes have become big sellers in recent years, and for a reason. Actually, for several reasons. One reason is they serve as excellent toolkits for web designers who have large and varied clienteles. The best multipurpose themes, like those presented here, are popular for other reasons as well. They […] Full Article Sponsored Best WordPRess themes BeTheme Top WP themes Total WordPress Theme Wordpress Themes
me Women’s squad raises ₹20 lakh By www.thehindu.com Published On :: Mon, 04 May 2020 23:17:41 +0530 The Indian women’s hockey team’s efforts to crowd-fund support for poor and migrant workers has raised ₹20,01,130 through an 18-day online challenge.T Full Article Sport
me The matter of photography in the Americas / Natalia Brizuela and Jodi Roberts ; with contributions by Lisa Blackmore, Amy Sara Carroll, Marianela D'Aprile, María Fernanda Domínguez, Heloisa Espada, Rachel Price, Diana Ruiz, Tatiane Santa Ro By library.mit.edu Published On :: Sun, 16 Feb 2020 06:00:01 EST Rotch Library - TR184.B75 2018 Full Article
me The women of Atelier 17: modernist printmaking in midcentury New York / Christina Weyl By library.mit.edu Published On :: Sun, 16 Feb 2020 06:00:01 EST Rotch Library - NE538.N5 W49 2019 Full Article
me Mathias Goeritz: modernist art and architecture in Cold War Mexico / Jennifer Josten By library.mit.edu Published On :: Sun, 16 Feb 2020 06:00:01 EST Rotch Library - N6559.G64 J67 2018 Full Article
me For your pleasure: Johannes Brus, photoworks and sculptures / with an essay by Clément Chéroux By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N6888.B745 A4 2018 Full Article
me The Pre-Raphaelites and science / John Holmes By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Hayden Library - NX454.5.P7 H65 2018 Full Article
me Djordje Ozbolt: regaining memory loss / exhibition curator, Nicoletta Lambertucci By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N6488.I8 V433 2019 Y8 Full Article
me New design, neoplasticism: Nieuwe beelding / Piet Mondrian ; English translation by Harry Holtzman and Martin S. James By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N6948.5.D42 M6613 2019 Full Article
me I have forgotten the night / Joël Andrianomearisoa ; curated by Rina Ralay Ranaivo and Emmanuel Daydé By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N6488.I8 V433 2019 M28 Full Article
me It's about time: Pavilion of Applied Arts / curator, Ralph Rugoff ; artist, Marysia Lewandowska By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N6488.I8 V433 2019 A67 Full Article
me Altered states: Substanzen in der zeitgenössischen Kunst = substances in contemporary art / herausgegeben von = edited by Milena Mercer ; Texte = texts, Max Daly ... [and thirteen others] By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N8251.S555 A48 2018 Full Article
me Women, art and money in late Victorian and Edwardian England: the hustle and the scramble / Maria Quirk By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N8354.Q57 2019 Full Article
me Scott Vendes's Menice By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N6488.I8 V433 2019 B33 Full Article
me Touch me / Johannes Frandsen ; text, Mattias Lundblad By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - TR650.F73 2018 Full Article
me Le modèle noir: de Géricault à Matisse: Musée d'Orsay / [éditeur, Claude Pommereau] By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N8232.M6325 2019 Full Article
me Dorothy Iannone: a cookbook / Dorothy Iannone ; [edited by Clément Dirié] By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N6537.I26 A4 2018 Full Article
me The stronger we become: the South African pavilion / Dineo Seshee Bopape, Tracey Rose, Mawande Ka Zenzile ; curated by Nkule Mabaso, Nomusa Makhubu By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N6488.I8 V433 2019 S6 Full Article
me Biennale Arte 2019: may you live in interesting times: 11.05-24.11 Venezia Giardini/Arsenale By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N6488.I8 V433 2019 A1 Full Article
me T.C. Cannon: at the edge of America / edited by Karen Kramer ; with contributions by heather ahtone, Sherwin Bitsui, Caitlin Cooper, Frank Buffalo Hyde, Trevor Fairbrother, Santee Frazier, Joy Harjo, Joan Naviyuk Kane, Karen Kramer, Deana McCloud, America By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - NX512.C36 A4 2018 Full Article