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Author Correction: Morphing electronics enable neuromodulation in growing tissue




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Viral contamination in biologic manufacture and implications for emerging therapies




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Nanopore sequencing and the Shasta toolkit enable efficient de novo assembly of eleven human genomes




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Single-cell RNA counting at allele and isoform resolution using Smart-seq3




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Exposure to direct-to-consumer advertising is associated with overestimation of benefits regarding ultrahypofractionated radiation therapy for prostate cancer




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Clinical utility of the exosome based ExoDx Prostate(<i>IntelliScore</i>) EPI test in men presenting for initial Biopsy with a PSA 2–10 ng/mL




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MHD surrogate model for convection in electromagnetically levitated molten metal droplets processed using the ISS-EML facility

npj Microgravity, Published online: 16 March 2020; doi:10.1038/s41526-020-0099-7

MHD surrogate model for convection in electromagnetically levitated molten metal droplets processed using the ISS-EML facility




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Protein structural changes on a CubeSat under rocket acceleration profile

npj Microgravity, Published online: 23 April 2020; doi:10.1038/s41526-020-0102-3

Protein structural changes on a CubeSat under rocket acceleration profile




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The HDOCK server for integrated protein–protein docking




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Ex situ determination of freely dissolved concentrations of hydrophobic organic chemicals in sediments and soils: basis for interpreting toxicity and assessing bioavailability, risks and remediation necessity




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Simultaneous noninvasive recording of electrocardiogram and skin sympathetic nerve activity (neuECG)




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Simultaneous quantification of protein–DNA interactions and transcriptomes in single cells with scDam&amp;T-seq




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Lifespan-increasing drug nordihydroguaiaretic acid inhibits p300 and activates autophagy




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Short-term NAD<sup>+</sup> supplementation prevents hearing loss in mouse models of Cockayne syndrome




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Organotypic human skin culture models constructed with senescent fibroblasts show hallmarks of skin aging




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The aging human body shape




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npj Aging and Mechanisms of Disease




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High rate of durable remissions post autologous stem cell transplantation for core-binding factor acute myeloid leukaemia in second complete remission




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Rituximab for desensitization during HLA-mismatched stem cell transplantation in patients with a positive donor-specific anti-HLA antibody




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Donor-derived DNA variability in fingernails of acute myeloid leukemia patients after allogeneic hematopoietic stem cell transplantation detected by direct PCR




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NT5DC2 promotes tumor cell proliferation by stabilizing EGFR in hepatocellular carcinoma




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Irradiation induces cancer lung metastasis through activation of the cGAS–STING–CCL5 pathway in mesenchymal stromal cells




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Differential effectiveness of tyrosine kinase inhibitors in 2D/3D culture according to cell differentiation, p53 status and mitochondrial respiration in liver cancer cells




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QKI deficiency leads to osteoporosis by promoting RANKL-induced osteoclastogenesis and disrupting bone metabolism




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LncRNA <i>SNORD3A</i> specifically sensitizes breast cancer cells to 5-FU by sponging miR-185-5p to enhance UMPS expression




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NF-kappa B interacting long noncoding RNA enhances the Warburg effect and angiogenesis and is associated with decreased survival of patients with gliomas




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Chromosome 11 open reading frame 30 (C11orf30), calpain small subunit 1 (CAPNS1; CAPN4), signal transducer and activator of transcription 6 (STAT6) and ankyrin repeat domain 27 (ANKRD27) as diagnostic markers for eosinophilic esophagitis (EoE)

Genomewide association studies identified four genes that could serve as diagnostic markers and/or therapeutic targets for EoE.




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RNAi against therapeutic targets with short interfering ribonucleic neutrals (siRNNs)

siRNNs could enable RNAi knockdown of therapeutic targets in a broader range of cells and tissue types than siRNA.




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Extending therapeutic protein half-lives via fusion to affibodies with pH-dependent binding to neonatal Fc receptor

Fusing therapeutic proteins to affibodies with pH-dependent binding to neonatal Fc receptor could improve the proteins' half-lives.




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Angiopoietin 2 (ANG2; ANGPT2); placental growth factor (PGF; PlGF); tissue inhibitor of metalloproteinases 3 (TIMP3)

Mouse studies suggest inhibiting PGF could help treat hypertension.




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Topoisomerase II binding protein 1 (TOPBP1)

Mouse and cell culture studies suggest inhibiting TOPBP1 could help treat cancer.




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Tripartite motif containing 37 (TRIM37)

In vitro and mouse studies suggest inhibiting TRIM37 could help treat breast cancer.




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Resurrecting a magic bullet

Heidelberg Pharma has resuscitated a long-dead ADC toxin with updated conjugation techniques, and its partner Roche has thrown the company a lifeline that could help validate the platform.




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Neutralizing the negatives of RNAi

The siRNN technology that Solstice licensed from UCSD could take RNAi-based therapies to tissues outside the liver and expand their use to a host of new diseases.




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SciBX: Science-Business eXchange




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Tissue-resident ductal macrophages survey the mammary epithelium and facilitate tissue remodelling




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Bridging naïve and primed pluripotency




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Differentiation of transplanted haematopoietic stem cells tracked by single-cell transcriptomic analysis




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MicroRNA binding site polymorphism in inflammatory genes associated with colorectal cancer: literature review and bioinformatics analysis




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Oncolytic adenovirus encoding LIGHT (TNFSF14) inhibits tumor growth via activating anti-tumor immune responses in 4T1 mouse mammary tumor model in immune competent syngeneic mice




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TMB: a promising immune-response biomarker, and potential spearhead in advancing targeted therapy trials




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Immunostimulatory oncolytic virotherapy for multiple myeloma targeting 4-1BB and/or CD40




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UNC5B mediates G2/M phase arrest of bladder cancer cells by binding to CDC14A and P53




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High-purity orbital angular momentum states from a visible metasurface laser




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Machine intelligence lights up imaging




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Superfluid coating




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Engineering nanomedicines through boosting immunogenic cell death for improved cancer immunotherapy




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Nintedanib inhibits keloid fibroblast functions by blocking the phosphorylation of multiple kinases and enhancing receptor internalization




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An in vitro Förster resonance energy transfer-based high-throughput screening assay identifies inhibitors of SUMOylation E2 Ubc9




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Feeding back on ingestion