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Rh-Catalysed Hydroacyloxylation of Cyclopropenes: Regio- and Diastereoselective Synthesis of Acyloxycyclopropanes

Org. Chem. Front., 2024, Accepted Manuscript
DOI: 10.1039/D4QO01810A, Research Article
Ángel Manu Martínez, Gema Domínguez, Ines Alonso, Marta Palaín, Javier Perez-Castells
Cyclopropyl carboxylates are essential building blocks in biological and medicinal chemistry. However, their accessibility is severely limited by the need to pre-synthesise highly reactive cyclopropane derivatives. Herein, we report an...
The content of this RSS Feed (c) The Royal Society of Chemistry




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PIFA-Mediated cyclization of methyl(2-(1-phenylvinyl)phenyl)sulfane for the concise, flexible, and scalable de novo synthesis of C3-arylated benzo[b]thiophenes

Org. Chem. Front., 2024, Accepted Manuscript
DOI: 10.1039/D4QO01589D, Research Article
Xinya Liu, Olivier Provot, Christine Tran, Jean-Francois Soule, Abdallah Hamze
The well-decorated arylated benzo[b]thiophene scaffold is a pivotal structural motif with diverse applications in medicinal chemistry. This paper outlines a de novo synthesis of C3-arylated benzo[b]thiophenes, showcasing its flexibility and...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Influence of hydrogen bonds and π-π stacking on the self-assembly of aryldipyrrolidones

Org. Chem. Front., 2024, Accepted Manuscript
DOI: 10.1039/D4QO01577K, Research Article
Open Access
Pedro Ximenis, Llorenç Rubert, Heike Ehmann, Bartolome Soberats
We report on the self-assembly behaviour in solution and solid-state of two newly designed bisdendronized aryldipyrrolidones (BDP and NDP) dyes with two free N-H at the lactam positions. Interestingly, while...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Modular dehydrogenative cross-nucleophile coupling for direct construction of tetrasubstituted carbons

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO01641F, Research Article
Peng Wang, Qiang Wang, Meng Wang, Liang Wang, Lubin Xu, Xiong-Li Liu, Fangzhi Hu, Shuai-Shuai Li
An FeCl3-catalyzed cross-dehydrogenative coupling reaction for the construction of various types of C–Y (Y = C, N, O, S) bonds with air as a green oxidant.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Hemilabile P,N-Ligand-Assisted Gold Catalyzed Hiyama Allylation to Access Allylarenes and 1,4-Dienes Derivatives

Org. Chem. Front., 2025, Accepted Manuscript
DOI: 10.1039/D4QO01879F, Research Article
Yuanhao He, Wanping Ma, Yu Zhong, Yanfei Hu, Mingou Li, Fen Zhao, Zhonghua Xia, Baomin Fan
Oxidant-free gold-catalyzed reactions are emerging as a novel synthetic tool for organic transformations. Here in, we reported a hemilabile P,N-ligand-assisted gold-catalyzed Hiyama cross coupling reaction of aryl and alkenyl iodides...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Convergent Synthetic Approaches to Polycyclic Aromatic Dicarboximides

Org. Chem. Front., 2025, Accepted Manuscript
DOI: 10.1039/D4QO01828A, Review Article
Kazutaka Shoyama, Frank Wuerthner
Polycyclic aromatic dicarboximides (PADIs) as represented by naphthalene and perylene bis(dicarboximide) are useful molecules for a variety of functional materials and remain important synthetic targets for organic chemists. In this...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Rhodium-catalyzed synthesis of N-substituted 3-acylpyrroles from enaminones and vinylene carbonate

Org. Chem. Front., 2025, Accepted Manuscript
DOI: 10.1039/D4QO01816H, Research Article
Sheng-Jiao Yan, Jian-Bo Ma, Yi-Mai Yin, Xing-Mei Hu, Bi-Na Shao, Kun Huang, Qing-Sheng Zhao
Skeletal editing is a highly efficient strategy for modifying the core scaffolds of drug molecules, with multi-atomic editing as an emergent approach. Herein, we present a protocol for constructing N-substituted...
The content of this RSS Feed (c) The Royal Society of Chemistry




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π-extended regioisomeric dithienoacenes fused pyrenes: structures, properties, and application in field-effect transistors

Org. Chem. Front., 2025, Accepted Manuscript
DOI: 10.1039/D4QO01592D, Research Article
Bin Lu, Shiqian Zhang, Dong Liu, Wendong Jin, Dalin Li, Zhiqiang Liu, Tao He
The development of π-conjugated semiconducting molecules with fused rings has been a focus of research in organic electronics. In this study, optoelectronic and field-effect transistors (FET) properties of two novel...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Mechanistic insights into rhodium-catalyzed C−H activation and annulation using vinyl acetate to access cinnolines and cinnolin-4(1H)-ones

Org. Chem. Front., 2025, Accepted Manuscript
DOI: 10.1039/D4QO01734J, Research Article
Yuqin Wang, Yiling Zeng, Ya-Nan Tian, Zheng Liu, Jinhua Wang, Shuyou Chen, Shiqing Li
Transition metal-catalyzed C−H activation and annulation involving vinyl acetate remains a significant challenge, and the mechanistic process following vinyl insertion is ambiguous. Herein, we report the Rh(III)-catalyzed two-fold C−H activation...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Intermolecular Defluorinative 1,2-Diamination of Fluoroalkenyl Iodides with Sulfonamides: Synthesis of Acyclic and Cyclic Fluorinated 1,2-Enediamines

Org. Chem. Front., 2025, Accepted Manuscript
DOI: 10.1039/D4QO01913J, Research Article
Xue-Qiang Chu, Yu-Lan Chen, Chi Zhang, Xue-Ying Huang, Yu Ding, Danhua Ge, Zhi-Liang Shen
Alkene diamination represents one of the most straightforward strategies for 1,2-diamine derivatives synthesis. However, transition-metal-free 1,2-diamination of fluoroalkenes has been less studied. Here we report an intermolecular defluorinative vicinal diamination...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Telangana Cyber Security Bureau conducts digital awareness campaign for senior citizens




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Telangana CID arrests two involved in pan-India job fraud racket




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At Via Milano in Hyderabad, the pizza can wait, go for the chops




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Usha Rk on the visual splendour of Adi Shankaracharya’s Ashtakams

Usha Rk, former director of Jawaharlal Nehru Cultural Center (JNCC) of the Embassy of India in Moscow, shares her vision of bringing Adi Shankaracharya’s Ashtakams to life through a dance form




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Woman arrested after kidnap attempt in Koti Government Maternity Hospital

The accused was a habitual offender and had made a vain bid on Tuesday night, before being caught by the hospital staff and police on Wednesday




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Six awarded life imprisonment for trafficking Bangladeshi girls




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Cong. govt cheating paddy farmers on procurement: Kishan Reddy




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Telangana pharmaceutical industries logged 97 major fire accidents in past decade: Fire Services Director-General Y. Nagi Reddy

The new government would like to decentralise and set up pharma villages, in 10 clusters, Special Chief Secretary Jayesh Ranjan said




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Two from Hyderabad, including government employee, lose ₹50 lakh in separate scams




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Mahabubnagar District Education Officer in ACB net




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TGSRTC Karimnagar region to operate special buses to Arunachala Hill in Tamil Nadu on November 13




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GHMC official sentenced to one-year RI in ACB case




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Thousands gather for Chhath Puja at Bathukamma ghats

In addition to Hussainsagar, Chhath Puja is being celebrated at 49 other locations across the twin cities of Hyderabad and Secunderabad.




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Moneylenders push family to end life, man his daughter die, wife survives

Head of the family was being harassed and intimidated by two Nizamabad-based moneylenders




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₹4.8 crore loan fraud scheme unearthed at SBI Sanathnagar, eight more arrested




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HYDRAA created fear among encroachers and big builders and not common people: Telangana CM




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75th anniversary of Bharat Scouts and Guides celebrated




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Traffic diversions in Rachakonda from Friday 8 a.m. for CM’s visit to Yadadri-Bhuvanagiri district




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Nampally court takes cognisance of ED’s prosecution complaint against AgriGold




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When hope meets hurdles: stark reality of Telangana’s job market

The State’s job crisis has come back to haunt the Congress party, which rode to power last year on promises of employment. While local youth wait, worry, and exchange dreams about securing government jobs, short-term opportunities are drawing people from other States. This dynamic has transformed Telangana into a job magnet for outsiders but a desert for its own aspirants, reports Serish Nanisetti




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Cyberabad | Four arrested for vandalising Gandhi statue




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Mother-daughter duo to showcase Andhra Natyam and Perini Tandavam in Hyderabad

Duvvuri Vathsalendra redefines tradition by mastering Perini Thandavam and sharing its power on stage with her daughter Abhimanika




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‘Rahasyam Idham Jagath’ movie review: Earnest but far from engrossing

Director Komal R Bharadwaj’s Telugu indie ‘Rahasyam Idham Jagath’ is ambitious in using science, technology and stories from the Indian epics for an adventure drama, but falls short in its execution




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Telangana set to unveil new industrial sectoral policies 

Electric Mobility and Storage, Electronics, Life Sciences, Defence and Aerospace sectors to get new growth guiding documents as some existing policies have become outdated and those in other States are superior, senior official 




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Congress shedding ‘çrocodile tears’ over BCs welfare: BJP leader Laxman




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Raid on hospitals in Hyderabad and Secunderabad leads to seizure of controlled drugs

The raiding teams found substances which are are classified as controlled drugs and their sale and possession are strictly regulated under the Narcotic Drugs and Psychotropic Substances (NDPS) Act




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Ugandan woman sentenced to 13 years RI for smuggling drugs to Hyderabad

The woman was caught attempting to smuggle 3,900 grams of heroin, worth ₹25 crore, to Hyderabad




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Key agent in Cambodia job racket arrested in Delhi




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Hyderabad man loses ₹1.73 lakh trying to get 0% interest loan on insurance policy worth ₹10 lakh




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No more parties without permission: Telangana Excise Dept. to farmhouse owners




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Telangana Deputy CM seeks proposals for retaining wall to prevent monsoon flooding in Madhira




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Eleven transgenders arrested for public nuisance in Cyberabad




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Man arrested for sexually assaulting mother-in-law in Balapur




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Home guard injured after engineering student attempts to flee vehicle checking in Panjagutta




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HMWS&SB website taken down after reported hacking

Hyderabad Water Board website down for maintenance after redirection to unauthorised sites, no impact on regular services




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Varun Tej: ‘Matka’ entertains but does not glorify the gambler

Actor Varun Tej discusses his new Telugu film ‘Matka’, a fictional tale inspired by Ratan Khatri, set in Visakhapatnam of the 1960s and 70s




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Cockroach infestation found at CCMB canteen; hygiene violations flagged at Nacharam restaurants




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Charitable trust donates furniture to flood-affected residential school in Khammam




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Kishan Reddy slams Revanth government for failing farmers, challenges Rahul Gandhi to tour villages in Telangana




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U.S. doctors explore institutional collaboration with NIMS