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Copper-catalyzed tandem phosphorylative allenylation/cyclization of 1-(o-aminophenyl)prop-2-ynols with the P(O)–H species: access to C2-phosphorylmethylindoles

Org. Chem. Front., 2020, 7,980-986
DOI: 10.1039/D0QO00159G, Research Article
Xiao-Yan Liu, Yun-Xiang Zou, Hai-Liang Ni, Jing Zhang, Hong-Bo Dong, Long Chen
A novel method to synthesize C2-phosphorylmethylindoles via the carbocation formation initiated tandem phosphorylative allenylation/cyclization of 1-(o-aminophenyl)prop-2-ynols with the P(O)–H species has been developed.
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Chelation-assisted transition metal-catalysed C–H chalcogenylations

Org. Chem. Front., 2020, 7,1022-1060
DOI: 10.1039/C9QO01497G, Review Article
Wenbo Ma, Nikolaos Kaplaneris, Xinyue Fang, Linghui Gu, Ruhuai Mei, Lutz Ackermann
This review summarizes recent advances in C–S and C–Se formations via transition metal-catalyzed C–H functionalization utilizing directing groups to control the site-selectivity.
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Oxidative N-heterocyclic carbene-catalyzed [3 + 3] annulation reaction of enals with benzofuran-3-ones: efficient access to benzofuran-fused δ-lactones

Org. Chem. Front., 2020, 7,1011-1015
DOI: 10.1039/D0QO00161A, Research Article
Zhan-Yong Wang, Ting Yang, Kai-Kai Wang, Rongxiang Chen, Menghan Liu, Hongxin Liu
A facile route to benzofuran-fused δ-lactones was developed via an N-heterocyclic carbene-catalyzed [3 + 3] annulation reaction, giving the expected products in high yields (up to 99%) with excellent enantioselectivities (up to 98% ee).
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Construction of spirooxindole-fused spiropyrazolones containing contiguous three stereogenic centres via [3 + 2] annulation utilizing a ferrocene derived bifunctional phosphine catalyst

Org. Chem. Front., 2020, 7,1016-1021
DOI: 10.1039/D0QO00140F, Research Article
Wenjun Luo, Bingxuan Shao, Jingyi Li, Xiao Xiao, Dingguo Song, Fei Ling, Weihui Zhong
Regional and stereoselective construction of spirooxindole-fused spiropyrazolones containing contiguous three stereogenic centres via [3 + 2] annulation catalyzed by ferrocene derived bifunctional phosphine.
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Palladium-catalyzed double carbonylation of propargyl amines and aryl halides to access 1-aroyl-3-aryl-1,5-dihydro-2H-pyrrol-2-ones

Org. Chem. Front., 2020, 7,1006-1010
DOI: 10.1039/D0QO00007H, Research Article
Jun Ying, Zhengjie Le, Zhi-Peng Bao, Xiao-Feng Wu
A palladium-catalyzed carbonylative procedure for the synthesis of 1-aroyl-3-aryl-1,5-dihydro-2H-pyrrol-2-ones from propargyl amines and aryl halides with TFBen as the CO source has been developed.
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Total synthesis of tumor-associated KH-1 antigen core nonasaccharide via photo-induced glycosylation

Org. Chem. Front., 2020, Advance Article
DOI: 10.1039/D0QO00314J, Research Article
Bo-Han Li, Wenlong Yao, Hong Yang, Congying Wu, De-Cai Xiong, Yuxin Yin, Xin-Shan Ye
KH-1 antigen core nonasaccharide was efficiently assembled by photo-induced glycosylation.
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Double allylic defluorinative alkylation of 1,1-bisnucleophiles with (trifluoromethyl)alkenes: construction of all-carbon quaternary centers

Org. Chem. Front., 2020, Advance Article
DOI: 10.1039/D0QO00121J, Research Article
Yingying Cai, Hao Zeng, Chuanle Zhu, Chi Liu, Guangying Liu, Huanfeng Jiang
Synthesis of symmetric gem-difluoroalkene substituted products bearing all-carbon quaternary centers via double allylic defluorinative alkylation of 1,1-bisnucleophiles with (trifluoromethyl)alkenes.
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Discovery of new polycyclic polyprenylated acylphloroglucinols with diverse architectures as potent cyclooxygenase-2 inhibitors

Org. Chem. Front., 2020, Advance Article
DOI: 10.1039/D0QO00259C, Research Article
Shuangshuang Xie, Changxing Qi, Yulin Duan, Qianqian Xu, Yaping Liu, Yingying Huang, Xu Yin, Weiguang Sun, Yuan Zhou, Yonghui Zhang
Cyclooxygenase-2 (COX-2) is a significant therapeutic target of chronic inflammatory diseases.
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Visible-light mediated oxidative ring expansion of anellated cyclopropanes to fused endoperoxides with antimalarial activity

Org. Chem. Front., 2020, Advance Article
DOI: 10.1039/D0QO00168F, Research Article
Simon Budde, Felix Goerdeler, Johannes Floß, Peter Kreitmeier, Elliot F. Hicks, Oren Moscovitz, Peter H. Seeberger, Huw M. L. Davies, Oliver Reiser
Hetero- and carbocyclic anellated cyclopropanes were converted in one step by a visible light induced photooxidation to their corresponding polycyclic endoperoxides, which show promising antimalarial activity.
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Asymmetric Organocatalytic Double 1,6-Addition: Rapid Access to Chiral Chromans with Molecular Complexity

Org. Chem. Front., 2020, Accepted Manuscript
DOI: 10.1039/D0QO00354A, Research Article
Indranil Chatterjee, Sourav Roy, Suman Pradhan, Krishan Kumar
An organocatalytic cascade vinylogous double 1,6-addition strategy for the synthesis of chiral chroman derivatives is reported. The cascade reaction follows oxa-Michael/1,6-addition reactions between ortho-hydroxyphenyl-substituted para-quinone methadies and 2,4-dienal derivatives to...
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Turn-on fluorescence sensors based on dynamic intramolecular N→B-coordination

Org. Chem. Front., 2020, Advance Article
DOI: 10.1039/D0QO00267D, Research Article
Raphael Koch, Yu Sun, Andreas Orthaber, Antonio J. Pierik, Frank Pammer
A series of ten aryl-triazole-functionalized boranes bearing BMes2-groups and capable of forming intramolecular five-membered N→B-coordinated heterocycles, has been prepared by 1,3-dipolar cycloaddition.
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Organocatalytic 1,5-trifluoromethylthio-sulfonylation of vinylcyclopropane mediated by visible light in the water phase

Org. Chem. Front., 2020, Advance Article
DOI: 10.1039/D0QO00343C, Research Article
Junkai Liu, Hong Yao, Xinnan Li, Hongyu Wu, Aijun Lin, Hequan Yao, Jinyi Xu, Shengtao Xu
1,2-Difunctionalization has developed into a robust tool for the preparation of complex organic molecules, and remote difunctionalization has also aroused widespread interest to achieve pluripotency of difunctionalization.
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Preparation of a mechanically interlocked polymer from a linear supramolecular polymer

Org. Chem. Front., 2020, Advance Article
DOI: 10.1039/D0QO00315H, Research Article
Zibin Zhang, Kechang Sun, Leqiong Jin, Chunsong Xie, Shijun Li
We transformed a linear supramolecular polymer into a mechanically interlocked polymer by photoisomerization.
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Hyperforones A–C, benzoyl-migrated [5.3.1]-type polycyclic polyprenylated acylphloroglucinols from Hypericum forrestii

Org. Chem. Front., 2020, 7,1070-1076
DOI: 10.1039/D0QO00152J, Research Article
Wei-Jia Lu, Wen-Jun Xu, Yan-Qiu Zhang, Yi-Ran Li, Xin Zhou, Qi-Ji Li, Hao Zhang, Jun Luo, Ling-Yi Kong
Unprecedented benzoyl-migrated polycyclic polyprenylated acylphloroglucinols with a unique C-1 H-substituted bicyclo[5.3.1]hendecane framework, hyperforones A–C (1–3), were isolated from Hypericum forrestii.
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Discrete boronate ester ladders from the dynamic covalent self-assembly of oligo(phenylene ethynylene) derivatives and phenylenebis(boronic acid)

Org. Chem. Front., 2020, 7,1082-1094
DOI: 10.1039/D0QO00083C, Research Article
Vasileios Drogkaris, Brian H. Northrop
Reversible boronate ester chemistry enables the controlled, dynamic self-assembly of olig(phenylene ethynylene)s into highly conjugated ladder frameworks.
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Insights into N-heterocyclic carbene and Lewis acid cooperatively catalyzed oxidative [3 + 3] annulation reactions of α,β-unsaturated aldehyde with 1,3-dicarbonyl compounds

Org. Chem. Front., 2020, 7,1113-1121
DOI: 10.1039/D0QO00091D, Research Article
Xinghua Wang, Yang Wang, Jinshuai Song, Donghui Wei
N-Heterocyclic carbene and Lewis acid cooperatively catalyzed oxidative [3 + 3] annulation reactions of 1,3-dicarbonyl compounds have been systematically studied in theory.
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Access to branched allylsilanes by nickel-catalyzed regioselective hydrosilylation of allenes

Org. Chem. Front., 2020, 7,1132-1136
DOI: 10.1039/D0QO00156B, Research Article
Jia-Hao Zeng, Jun-Jia Chen, Li Chen, Zhuang-Ping Zhan
A Ni(acac)2/Xantphos-catalyzed hydrosilylation of allenes has been developed.
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Toward C2-nitrogenated chromones by copper-catalyzed β-C(sp2)–H N-heteroarylation of enaminones

Org. Chem. Front., 2020, 7,1107-1112
DOI: 10.1039/D0QO00065E, Research Article
Tian Luo, Jie-Ping Wan, Yunyun Liu
The synthesis of C2-nitrogenated chromones has been performed via reactions of enaminones and nitrogen nucleophiles based on an unconventional β-C–H bond functionalization and a featured chromone annulation of enaminones.
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Direct synthesis of annulated indoles through palladium-catalyzed double alkylations

Org. Chem. Front., 2020, 7,1149-1157
DOI: 10.1039/D0QO00135J, Research Article
Yadong Gao, Jianhua Li, Songlin Bai, Daoquan Tu, Chao Yang, Zhiwen Ye, Bingcheng Hu, Xiangbing Qi, Chao Jiang
A facile, one-step synthesis of annulated indoles from (N–H) indoles and dibromoalkanes was developed through a palladium-catalyzed double alkylation process.
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The origin of regioselectivity in Cu-catalyzed hydrocarbonylative coupling of alkynes with alkyl halides

Org. Chem. Front., 2020, 7,1137-1148
DOI: 10.1039/D0QO00214C, Research Article
Shengnan Liu, Jianbiao Liu, Qiong Wang, Jin Wang, Fang Huang, Wenjuan Wang, Chuanzhi Sun, Dezhan Chen
Steric interactions mediate a switch between a ketone and allylic alcohol in Cu-catalyzed hydrocarbonylative coupling of alkynes with alkyl halides.
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Recent developments in palladium-catalyzed C–S bond formation

Org. Chem. Front., 2020, Advance Article
DOI: 10.1039/D0QO00377H, Research Article
Jianxiao Li, Shaorong Yang, Wanqing Wu, Huanfeng Jiang
This review summarized the recent developments in palladium-catalyzed C–S bond formation involving sulfenylation and sulfonylation reactions.
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Tricarabrols A–C, three anti-inflammatory sesquiterpene lactone trimers featuring a methylene-tethered linkage from Carpesium faberi

Org. Chem. Front., 2020, Advance Article
DOI: 10.1039/D0QO00093K, Research Article
Jie Yuan, Xuelan Wen, Chang-Qiang Ke, Tian Zhang, Ligen Lin, Sheng Yao, Jason D. Goodpaster, Chunping Tang, Yang Ye
Three anti-inflammatory trimeric compounds constructed from carabrol-type sesquiterpenoids through a methylene-tethered linkage were characterized from Carpesium faberi.
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Chiral strong Brønsted acid-catalyzed enantioselective addition reaction of simple olefins with ethyl glyoxylate

Org. Chem. Front., 2020, Advance Article
DOI: 10.1039/D0QO00448K, Research Article
Jun Kikuchi, Yuki Aizawa, Masahiro Terada
An enantioselective intermolecular addition reaction of 1,1,2-trisubstituted and 1,2- disubstituted simple olefins with ethyl glyoxylate was developed using F10BINOL-derived N-sulfonyl phosphoramide as a chiral strong Brønsted acid catalyst.
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Phosphine/Palladium Cooperative Catalysis: Enantioselective [5+4] Annulations of ortho-Quinone Methides and Vinylethylene Carbonates

Org. Chem. Front., 2020, Accepted Manuscript
DOI: 10.1039/D0QO00128G, Research Article
Chao Xia, Dong-Chao Wang, Gui-Rong Qu, Hai-Ming Guo
Highly enantioselective [5+4] annulations of ortho-quinone methides with vinylethylene carbonates were enabled by phosphine/palladium asymmetric cooperative catalysis for the first time. Efficient synthesis of various nine-membered benzo-heterocycles was achieved in...
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Mechanism and Origins of Stereo- and Enantioselectivities of Palladium-Catalyzed Hydroamination of Racemic Internal Allenes via Dynamic Kinetic Resolution: A Computational Study

Org. Chem. Front., 2020, Accepted Manuscript
DOI: 10.1039/D0QO00174K, Research Article
Zhenzhen Wu, Mei Zhang, Yu Shi, Genping Huang
Density functional theory calculations have been performed to investigate the Pd-catalyzed hydroamination of racemic internal allenes with pyrazoles. The computations show that the originally proposed reaction mechanisms initiated by the...
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Catalyst-Controlled Formal [4+1] Annulation of N-Vinyl Fluorenone Nitrones and Allenoates to Prepare Spirofluorenylpyrrolines

Org. Chem. Front., 2020, Accepted Manuscript
DOI: 10.1039/D0QO00224K, Research Article
Cui Wei, Jin-Qi Zhang, Jia-Jie Zhang, Cui Liang, Dong-Liang Mo
We report a readily commercial Gimeracil-catalyzed formal [4+1] annulation approach for the synthesis of spirofluorenylpyrrolines in good yields with high diastereoselectivity from easily available N-vinyl fluorenone nitrones and allenoates. The...
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Rhodium(III)-catalyzed synthesis of 3-trifluoromethylindanones from N-Methoxybenzamides via C-H activation and Claisen/Retro-Claisen reaction

Org. Chem. Front., 2020, Accepted Manuscript
DOI: 10.1039/D0QO00330A, Research Article
Satyasheel Sharma, Bharatkumar Chaudhary, Neeraj Kulkarni
The Rhodium(III)-catalyzed reaction of N-methoxybenzamides as a directing group with β-trifluoromethyl-α,β-unsaturated ketones is reported. The reaction involved sp2 C−H activation, followed by Claisen condensation involving C-N bond cleavage to form...
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Targeted Isolation of Two Disesquiterpenoids Macrocephadiolides A and B from Ainsliaea macrocephala using Molecular Networking-based Dereplication Strategy

Org. Chem. Front., 2020, Accepted Manuscript
DOI: 10.1039/D0QO00030B, Research Article
Yong-Mei Ren, Shuaizhen Zhou, Tian Zhang, Meijia Qian, Rui Zhang, Sheng Yao, Hong Zhu, Chunping Tang, Ligen Lin, Yang Ye
A molecular networking-based dereplication strategy was applied to the phytochemical investigation of Ainsliaea macrocephala, leading to the isolation of two novel disesquiterpenoids macrocephadiolides A (1) and B (2). Their structures,...
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The art of scientific writing : from student reports to professional publications in chemistry and related fields / Hans F. Ebel, Claus Bliefert, William E. Russey

Ebel, Hans Friedrich




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Handbook of writing for the mathematical sciences / Nicholas J. Higham

Higham, N. J




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Writing scientific English : a textbook of English as a foreign language for students of physical and engineering sciences / John Swales

Swales, John




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Molecular engineering of nanosystems / Edward A. Rietman

Rietman, Ed




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Nanoscale calibration standards and methods : dimensional and related measurements in the micro- and nanometer range / edited by Günter Wilkening, Ludger Koenders




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Principles of nanotechnology : molecular-based study of condensed matter in small systems / G. Ali Mansoori

Mansoori, G. A. (G. Ali)




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Nanotechnology : basic calculations for engineers and scientists / Louis Theodore

Theodore, Louis




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Handbook of semiconductor nanostructures and nanodevices / edited by Alexander A. Balandin, Kang L. Wang




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Nanodevices for the life sciences / edited by Challa S.S.R. Kumar




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Nanocatalysis / U. Heiz, U. Landman (eds.)




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Biomolecular computation for bionanotechnology / Jian-Qin Liu, Katsunori Shimohara

Liu, Jian-Qin




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Nanocharacterisation / edited by Angus I. Kirkland and John L. Hutchison




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Nanotechnology for biology and medicine : at the building block level / Gabriel A. Silva, Vladimir Parpura, editors




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Carbon materials and nanotechnology / Anke Krueger ; [translator, Stefan Brammer]

Krueger, Anke, 1973-




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A laboratory course in nanoscience and nanotechnology / Gérrard Eddy Jai Poinern

Poinern, Gérrard Eddy Jai




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Biogenic production of gold and silver nanoparticles using extracts from indigenous Australian plants : their synthesis, optimisation, characterisation and antibacterial activities / Monali Shah

Shah, Monali, author




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Nanomaterials and nanocomposites : zero- to three-dimensional materials and their composites / edited by Visakh P.M. and Maria José Martínez Morlanes




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[ASAP] Scale-Up of Room-Temperature Constructive Quantum Interference from Single Molecules to Self-Assembled Molecular-Electronic Films

Journal of the American Chemical Society
DOI: 10.1021/jacs.9b13578




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[ASAP] Selective Mechanochemical Monoarylation of Unbiased Dibromoarenes by <italic toggle="yes">in Situ</italic> Crystallization

Journal of the American Chemical Society
DOI: 10.1021/jacs.0c01739




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[ASAP] Ship-in-a-Bottle Preparation of Long Wavelength Molecular Antennae in Lanthanide Metal–Organic Frameworks for Biological Imaging

Journal of the American Chemical Society
DOI: 10.1021/jacs.0c01426




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[ASAP] Tug of War between Condensate Phases in a Minimal Macromolecular System

Journal of the American Chemical Society
DOI: 10.1021/jacs.0c01881




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[ASAP] Visible-Light-Driven Rotation of Molecular Motors in a Dual-Function Metal–Organic Framework Enabled by Energy Transfer

Journal of the American Chemical Society
DOI: 10.1021/jacs.0c03063