the Influence of the mechanical properties of biomaterials on degradability, cell behaviors and signaling pathways: current progress and challenges By pubs.rsc.org Published On :: Biomater. Sci., 2020, Advance ArticleDOI: 10.1039/D0BM00269K, Review ArticleLu Wang, Cunyang Wang, Shuai Wu, Yubo Fan, Xiaoming LiWe have clarified the influence of the mechanical properties of biomaterials on degradability and cell response, and also mechanical design targets and approaches.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
the Nanozyme-catalyzed oxygen release from calcium peroxide nanoparticles for accelerated hypoxia relief and image-guided super-efficient photodynamic therapy By pubs.rsc.org Published On :: Biomater. Sci., 2020, Advance ArticleDOI: 10.1039/D0BM00187B, PaperYuping Hu, Xuechun Wang, Peng Zhao, Hao Wang, Wei Gu, Ling YeThe accelerated O2 release from CaO2 catalyzed by MnO2 nanozyme leads to a rapid and efficient hypoxia relief, an increased yield of 1O2, a down-regulated HIF-1α and VEGF, and eventually a super-efficient PDT.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
the Delivery of dual miRNA through CD44-targeted mesoporous silica nanoparticles for enhanced and effective triple-negative breast cancer therapy By pubs.rsc.org Published On :: Biomater. Sci., 2020, Advance ArticleDOI: 10.1039/D0BM00015A, PaperManisha Ahir, Priyanka Upadhyay, Avijit Ghosh, Sushmita Sarker, Saurav Bhattacharya, Payal Gupta, Swatilekha Ghosh, Sreya Chattopadhyay, Arghya AdhikaryCationic Mesoporous silica Nanoparticle coated with hyaluronic acid conjugated polymer (HA-Dual miRNA Np) facilitated enhanced dual miRNA loading, efficient delivery and significantly inhibited tumor growth as well as retarded metastasis in triple-negative breast cancer.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
the Fixed-point “blasting” triggered by second near-infrared window light for augmented interventional photothermal therapy By pubs.rsc.org Published On :: Biomater. Sci., 2020, Advance ArticleDOI: 10.1039/D0BM00372G, PaperYongbin Cao, Boshu Ouyang, Xiaowei Yang, Qin Jiang, Lin Yu, Shun Shen, Jiandong Ding, Wuli YangTumors were effectively destroyed by a mild photothermal effect and the subsequent gas mechanical damage triggered by NIR-II light.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
the Correction: An eximious and affordable GSH stimulus-responsive poly(α-lipoic acid) nanocarrier bonding combretastatin A4 for tumor therapy By pubs.rsc.org Published On :: Biomater. Sci., 2020, Advance ArticleDOI: 10.1039/D0BM90037K, Correction Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Zhilin Liu, Na Shen, Zhaohui Tang, Dawei Zhang, Lili Ma, Chenguang Yang, Xuesi ChenTo cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
the Polydopamine-assisted one-step modification of nanofiber surfaces with adenosine to tune the osteogenic differentiation of mesenchymal stem cells and the maturation of osteoclasts By pubs.rsc.org Published On :: Biomater. Sci., 2020, Advance ArticleDOI: 10.1039/C9BM01990A, PaperTaufiq Ahmad, Hayeon Byun, Hyeok Jun Shin, Jinkyu Lee, Sajeesh Kumar Madhurakkat Perikamana, Eun Mi Kim, Young Min Shin, Heungsoo ShinAdenosine and its receptors have emerged as alternative targets to control cellular functions for bone healing.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
the The potential role of borophene as a radiosensitizer in boron neutron capture therapy (BNCT) and particle therapy (PT) By pubs.rsc.org Published On :: Biomater. Sci., 2020, Advance ArticleDOI: 10.1039/D0BM00318B, CommunicationPengyuan Qi, Qianyuan Chen, Dong Tu, Songhuan Yao, Yupeng Zhang, Jike Wang, Conghua Xie, Chunxu Pan, Hao PengThe potential role of borophene as a radiosensitizer in PT and BNCT was investigated.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
the Messenger RNA/polymeric carrier nanoparticles for delivery of heme oxygenase-1 gene in the post-ischemic brain By pubs.rsc.org Published On :: Biomater. Sci., 2020, Advance ArticleDOI: 10.1039/D0BM00076K, PaperJungju Oh, Sang-Mi Kim, Eun-Hye Lee, Minkyung Kim, Youngki Lee, Seung Hwan Ko, Ji Hoon Jeong, Chang-Hwan Park, Minhyung LeeHeme oxygenase-1 messenger RNA (HO1-mRNA) was delivered into the post-ischemic brain, using a polymeric carrier. Therapeutic efficacy of HO1-mRNA delivery was compared with that of HO1-plasmid DNA (HO1-pDNA) in ischemia-reperfusion rat models.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
the Dendritic cells reprogrammed by CEA messenger RNA loaded multi-functional silica nanospheres for imaging-guided cancer immunotherapy By pubs.rsc.org Published On :: Biomater. Sci., 2020, Advance ArticleDOI: 10.1039/D0BM00395F, CommunicationYue Hu, Yuyin Tang, Xiao-Jing Zhang, Xiao-Tong Yang, Ying-Ying Tang, Su Li, Linyu Hu, Peng Chen, Dong ZhuMulti-functional and hierarchically structured silica nanospheres are rationally designed and fabricated, which encapsulate quantum dots to permit near infrared deep tissue imaging and are loaded with carcinoembryonic antigen messenger RNA (CEAmRNA) to enable stable and abundant antigen expression in DCs.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
the A TRACER culture invasion assay to probe the impact of cancer associated fibroblasts on head and neck squamous cell carcinoma cell invasiveness By pubs.rsc.org Published On :: Biomater. Sci., 2020, Advance ArticleDOI: 10.1039/C9BM02017A, PaperTeresa Dean, Nancy T. Li, Jose L. Cadavid, Laurie Ailles, Alison P. McGuiganA novel 3D in vitro co-culture platform to explore the interactions between cancer-associated fibroblasts and tumour cells that drive increased tumour cell invasion and the impact of matrix density.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
the A photothermal-hypoxia sequentially activatable phase-change nanoagent for mitochondria-targeting tumor synergistic therapy By pubs.rsc.org Published On :: Biomater. Sci., 2020, Advance ArticleDOI: 10.1039/D0BM00003E, PaperJia Qu, Dengke Teng, Guoqing Sui, Shihui Guan, Yang Wang, Qimeihui Wang, Yuanqiang Lin, Haitao Ran, Zhigang Wang, Hui WangThe advantages of PCM@Lip/IT NPs include mitochondrial-targeting, on-demand drug release, and prodrug activation by hypoxia with guidance/monitoring by PA and FL imaging.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
the Long-term delivery of alendronate through an injectable tetra-PEG hydrogel to promote osteoporosis therapy By pubs.rsc.org Published On :: Biomater. Sci., 2020, Advance ArticleDOI: 10.1039/D0BM00376J, PaperDawei Li, Jin Zhou, Mingming Zhang, Yuanzheng Ma, Yanyu Yang, Xue Han, Xing WangAn alendronate-loaded tetra-PEG hydrogel, as an injectable and effective drug carrier, regulates the optimized release of therapeutic cargoes to promote osteoporosis therapy and bone regeneration.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
the Protein cages and virus-like particles: from fundamental insight to biomimetic therapeutics By pubs.rsc.org Published On :: Biomater. Sci., 2020, Advance ArticleDOI: 10.1039/D0BM00159G, MinireviewNicole F. Steinmetz, Sierin Lim, Frank SainsburyProtein cages found in nature have evolved for a variety of purposes and this review focuses on how they are being co-opted for use in immunotherapy and therapeutic delivery.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
the A pH-responsive dissociable mesoporous silica-based nanoplatform enabling efficient dual-drug co-delivery and rapid clearance for cancer therapy By pubs.rsc.org Published On :: Biomater. Sci., 2020, Accepted ManuscriptDOI: 10.1039/D0BM00204F, PaperYongju He, Linjie Shao, Ibrahim Usman, Yao Hu, Anqiang Pan, Shuquan Liang, Hui XuThe dilemma between tumor accumulation and renal clearance has severely limited the efficacy of mesoporous silica-based drug nanocarrier in cancer therapy. Herein, a pH-responsive dissociable mesoporous silica-based nanoplatform with efficient...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
the Overview of the application of inorganic nanomaterials in cancer photothermal therapy By pubs.rsc.org Published On :: Biomater. Sci., 2020, Advance ArticleDOI: 10.1039/D0BM00222D, Review ArticleNatanael Fernandes, Carolina F. Rodrigues, André F. Moreira, Ilídio J. CorreiaCancer photothermal therapy (PTT) has captured the attention of researchers worldwide due to its localized and trigger-activated therapeutic effect.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
the Photothermal augment stromal disrupting effects for enhanced Abraxane synergy chemotherapy in pancreatic cancer PDX mode By pubs.rsc.org Published On :: Biomater. Sci., 2020, Advance ArticleDOI: 10.1039/D0BM00549E, PaperTianhong Teng, Ronggui Lin, Ziguo Lin, Kun Ke, Xianchao Lin, Maoen Pan, Da Zhang, Heguang HuangPreparation of Abraxane@MoSe2 and its PTT effect augment stromal disrupting effects for enhanced Abraxane synergy chemotherapy in pancreatic cancer PDX mode.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
the 19 F magnetic resonance imaging enabled real-time, non-invasive and precise localization and quantification of the degradation rate of hydrogel scaffolds in vivo By pubs.rsc.org Published On :: Biomater. Sci., 2020, Advance ArticleDOI: 10.1039/D0BM00278J, PaperQinghua Li, Zujian Feng, Huijuan Song, Jianhua Zhang, Anjie Dong, Deling Kong, Weiwei Wang, Pingsheng Huang 19 F MRI is able to precisely monitor the localization and quantify the degradation rate of implantable/injectable hydrogels in real-time and noninvasive manner, with no interference of endogenous background signals and limitation of penetration depth.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
the A Fe3+-crosslinked pyrogallol-tethered gelatin adhesive hydrogel with antibacterial activity for wound healing By pubs.rsc.org Published On :: Biomater. Sci., 2020, Advance ArticleDOI: 10.1039/D0BM00188K, PaperNing Han, Ziyang Xu, Chunyan Cui, Yuan Li, Dongfei Zhang, Meng Xiao, Chuanchuan Fan, Tengling Wu, Jianhai Yang, Wenguang LiuA tunicate-inspired gelatin-based hydrogel prepared by a simple mixing method, exhibits strong adhesion and antibacterial capacity, and facilitates wound healing.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
the Disulfiram-Gold-Nanorod Integrate for Effective Tumor Targeting and Photothermal-Chemical Synergistic Therapy By pubs.rsc.org Published On :: Biomater. Sci., 2020, Accepted ManuscriptDOI: 10.1039/D0BM00062K, PaperChaoli Xu, Ting Zhang, Guangming Lu, Kun Chen, Jun Tao, Yunlei Zhang, Zhaogang Teng, Bin YangHerein, we successfully constructed a combined therapeutic nanoplatform with high tumor targeting for cancer treatment by integrating gold nanorods with disulfiram (denoted Au-DSF). The Au-DSF integrates possess a uniform length...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
the Fluorescence Imaging-Guided Multifunctional Liposomes for Tumor-Specific Phototherapy for Laryngeal carcinoma By pubs.rsc.org Published On :: Biomater. Sci., 2020, Accepted ManuscriptDOI: 10.1039/D0BM00249F, PaperDi Wu, zheng zhao, nan wang, xinrui zhang, honghong yan, xiaoqi chen, yunyun fan, weiwei liu, xuekui liuReliable diagnosed and efficient targeted therapy regime is important and may in turn lead to more effective laryngeal carcinoma treatments. Multifunctional nano-theranostic agents demonstrate great potential in tumor theranostic applications....The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
the A disulfide based low molecular weight gel for the selective sustained release of biomolecules By pubs.rsc.org Published On :: Biomater. Sci., 2020, Advance ArticleDOI: 10.1039/D0BM00508H, PaperNitin D. Bansode, Kotagudda Ranganath Sindhu, Chloe Morel, Murielle Rémy, Julien Verget, Claudine Boiziau, Philippe BarthélémyConstructing biocompatible soft materials via supramolecular approaches remains an important challenge for in vivo applications.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
the A conductive PEDOT/alginate porous scaffold as a platform to modulate the biological behaviors of brown adipose-derived stem cells By pubs.rsc.org Published On :: Biomater. Sci., 2020, Advance ArticleDOI: 10.1039/C9BM02012H, PaperBoguang Yang, Fanglian Yao, Lei Ye, Tong Hao, Yabin Zhang, Lei Zhang, Dianyu Dong, Wancai Fang, Yan Wang, Xiaoyang Zhang, Changyong Wang, Junjie LiThe development of three-dimensional conductive scaffolds is vital to support the adhesion, proliferation and myocardial differentiation of stem cells in cardiac tissue engineering.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
the Naturally available hypericin undergoes electron transfer for type I photodynamic and photothermal synergistic therapy By pubs.rsc.org Published On :: Biomater. Sci., 2020, 8,2481-2487DOI: 10.1039/D0BM00021C, PaperZhen Ke, Aize Xie, Jianjiao Chen, Zhenyuan Zou, Lei Shen, Yansong Dai, Dengfeng ZouHypericin undergoing electron transfer can be used for type I PDT and PTT.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
the In situ conversion of rose bengal microbubbles into nanoparticles for ultrasound imaging guided sonodynamic therapy with enhanced antitumor efficacy By pubs.rsc.org Published On :: Biomater. Sci., 2020, 8,2526-2536DOI: 10.1039/C9BM02046B, PaperRui Hou, Xiaolong Liang, Xiaoda Li, Xu Zhang, Xiaotu Ma, Fan WangSonosensitizer microbubbles enhance drug accumulation and the antitumor efficacy of sonodynamic therapy by ultrasound mediated micro to nano conversion.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
the Tumor localization of oncolytic adenovirus assisted by pH-degradable microgels with JQ1-mediated boosting replication and PD-L1 suppression for enhanced cancer therapy By pubs.rsc.org Published On :: Biomater. Sci., 2020, 8,2472-2480DOI: 10.1039/D0BM00172D, PaperHaishi Qiao, Xingmei Chen, Qiming Wang, Junmei Zhang, Dechun Huang, Enping Chen, Hongliang Qian, Yinan Zhong, Qi Tang, Wei ChenIllustration of pH-degradable microgels (MGs) for the simultaneous encapsulation of OA and JQ1 for an enhanced oncolytic viral treatment with JQ1-meidated boosting viral replication and PD-L1 suppression.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
the Biomimic strategies for modulating the interaction between particle adjuvants and antigen-presenting cells By pubs.rsc.org Published On :: Biomater. Sci., 2020, 8,2366-2375DOI: 10.1039/C9BM02098E, Review ArticleJie Wu, Guanghui MaThe design strategies of particle adjuvants by mimicking natural pathogens to strengthen their interaction with antigen-presenting cells.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
the Dual-responsive click-crosslinked micelles designed for enhanced chemotherapy for solid tumors By pubs.rsc.org Published On :: Biomater. Sci., 2020, 8,2507-2513DOI: 10.1039/D0BM00078G, PaperRong Jin, Jing Sun, Liefu Zhou, Xuelian Guo, Aoneng CaoCore-crosslinked dual-responsive micelles can be readily constructed from a pair of clickable copolymers and applied for controlled release of anticancer drugs in cancer therapy.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
the A nanosystem loaded with perfluorohexane and rose bengal coupled upconversion nanoparticles for multimodal imaging and synergetic chemo-photodynamic therapy of cancer By pubs.rsc.org Published On :: Biomater. Sci., 2020, 8,2488-2506DOI: 10.1039/C9BM02081K, PaperHai-yan Wang, Li Hou, Hai-liang Li, Xu Wang, Yang Cao, Bo-yu Zhang, Jing-tao Wang, Shi-jie Wei, Hong-wan Dang, Hai-tao RanA novel nanosystem (FURH-PFH-NPs) combined with LIFU and laser irradiation realized multimodal imaging, targeted release of HCPT, UCNPs-RB and synergetic chemo-photodynamic therapy of cancer.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
the Enhanced selectivity, cellular uptake, and in vitro activity of an intrinsically fluorescent copper–tirapazamine nanocomplex for hypoxia targeted therapy in prostate cancer By pubs.rsc.org Published On :: Biomater. Sci., 2020, 8,2420-2433DOI: 10.1039/C9BM01905G, PaperVera L. Silva, Abdessamad Kaassis, Ashkan Dehsorkhi, Cédrik-Roland Koffi, Maja Severic, Moustafa Abdelhamid, Duuamene Nyimanu, Christopher J. Morris, Wafa’ T. Al-JamalCu(TPZ)2 complex as a promising hypoxia selective cytotoxin in prostate cancer.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
the Nanomedicine – a promising therapy for hematological malignancies By pubs.rsc.org Published On :: Biomater. Sci., 2020, 8,2376-2393DOI: 10.1039/D0BM00129E, Review ArticleLifen Huang, Jun Huang, Junbin Huang, Hongman Xue, Zhiqing Liang, Jun Wu, Chun ChenNanoparticles (NPs) are used for the diagnosis and treatment of hematological tumors by loading various pharmacodynamic molecules.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
the A thermo-responsive, self-assembling biointerface for on demand release of surface-immobilised proteins By pubs.rsc.org Published On :: Biomater. Sci., 2020, 8,2673-2681DOI: 10.1039/C9BM01957J, PaperAngela Saccardo, Mikhail Soloviev, Enrico FerrariEngineering of the neuronal SNARE proteins yields chimeric bio-materials that reversibly assemble and disassemble at set temperatures.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
the The electrospinning of a thermo-responsive polymer with peptide conjugates for phenotype support and extracellular matrix production of therapeutically relevant mammalian cells By pubs.rsc.org Published On :: Biomater. Sci., 2020, 8,2611-2626DOI: 10.1039/C9BM01965K, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.F. A. A. Ruiter, L. E. Sidney, K. L. Kiick, J. I. Segal, C. Alexander, F. R. A. J. RoseThe fabrication and application of a biocompatible peptide conjugated thermo-responsive fibrous scaffolds for cellular phenotype support and enzymatic-free passaging of mammalian cells.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
the Biodegradable nanocomposite fibrous scaffold mediated local delivery of vancomycin for the treatment of MRSA infected experimental osteomyelitis By pubs.rsc.org Published On :: Biomater. Sci., 2020, 8,2653-2665DOI: 10.1039/D0BM00140F, PaperAmit G. Krishnan, Raja Biswas, Deepthy Menon, Manitha B. NairThe study shows the development of a biodegradable bi-functional composite scaffold that can reduce bacterial infection, while promotes bone regeneration in osteomyelitis, without the need for revision surgery.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
the Advances in living cell-based anticancer therapeutics By pubs.rsc.org Published On :: Biomater. Sci., 2020, 8,2344-2365DOI: 10.1039/D0BM00036A, Review ArticleHe Dong, Xiao Xu, Leikun Wang, Ran MoThis review summarizes recent advances in the applications of living cells as drug carriers or active drugs for anticancer drug delivery and cancer therapy.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
the Optically controlled hybrid metamaterial of plasmonic spiky gold inbuilt graphene sheets for bimodal imaging guided multimodal therapy By pubs.rsc.org Published On :: Biomater. Sci., 2020, Advance ArticleDOI: 10.1039/D0BM00312C, PaperKunnumpurathu Jibin, Jayaram S. Prasad, Giridharan Saranya, Sachin J. Shenoy, Kaustabh K. Maiti, Ramapurath S. JayasreeGold–graphene nanohybrid for simultaneous dual-imaging guided triple therapy as a new paradigm in light-triggered cancer theranostics. The material demonstrates excellent therapeutic efficacy and treatment monitoring features.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
the A biomimetic orally targeted delivery of Bindarit for immunotherapy of atherosclerosis By pubs.rsc.org Published On :: Biomater. Sci., 2020, Accepted ManuscriptDOI: 10.1039/D0BM00418A, PaperLuqi Yin, Cuiping Peng, Yue Tang, Yuchuan Yuan, Jiaxing Liu, Tingting Xiang, Feila Liu, Zhou Xing, Xiaohui LiMonocyte chemoattractant protein-1 (MCP-1) plays an important role in the development of atherosclerosis. However, the application of bindarit (a specific synthetic inhibitor of MCP-1) in atherosclerosis has not been confirmed...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
the Integrated network pharmacology and targeted metabolomics to reveal the mechanism of nephrotoxicity of triptolide By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,850-861DOI: 10.1039/C9TX00067D, PaperWei Huang, Chuanxin Liu, Lijuan Xie, Yuming Wang, Yanyan Xu, Yubo LiIntegrated network pharmacology and targeted metabolomics to reveal the nephrotoxicity mechanism of triptolide.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
the Eco-friendly synthesis of glutathione-capped CdTe/CdSe/ZnSe core/double shell quantum dots: their cytotoxicity and genotoxicity effects on Chinese hamster ovary cells By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,868-874DOI: 10.1039/C9TX00113A, PaperNeo Mervyn Monaheng, Sundararajan Parani, Mary Gulumian, Oluwatobi Samuel OluwafemiIn this work, we report green one-pot synthesis, cytotoxicity and genotoxicity of glutathione-capped CdTe/CdSe/ZnSe heterostructured quantum dots (QDs) using a label-free xCELLigence RTCA system as well as the Cytokinesis Blocked Micronucleus assay.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
the Tin thiocarbonohydrazone complexes: synthesis, crystal structures and biological evaluation By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,862-867DOI: 10.1039/C9TX00109C, PaperJin Wang, Yu-Ting Wang, Yan Fang, Yan-Li Lu, Ming-Xue LiThree organotin thiocarbonohydrazone complexes have been synthesized, and growth inhibition assays indicated that complex 3 has the highest tumor cell selectivity.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
the miR-140-5p mediates bevacizumab-induced cytotoxicity to cardiomyocytes by targeting the VEGFA/14-3-3γ signal pathway By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,875-884DOI: 10.1039/C9TX00100J, PaperXuan-Ying Chen, Wei-Lin Huang, Xiao-Ping Peng, Yan-Ni Lv, Jun-He Li, Jian-Ping XiongBevacizumab (BVZ) is a widely investigated angiogenesis inhibitor in cancer patients. Although the anti-tumor effects has been verified, cardiotoxicity may be the most serious side-effect for BVZ.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
the Lipoic acid antagonizes paraquat-induced vascular endothelial dysfunction by suppressing mitochondrial reactive oxidative stress By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,918-927DOI: 10.1039/C9TX00186G, PaperLi Pang, Ping Deng, Yi-dan Liang, Jing-yu Qian, Li-Chuan Wu, Ling-ling Yang, Zheng-ping Yu, Zhou Zhouα-Lipoic acid antagonizes paraquat toxicity.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
the Environmental distribution of the neurotoxin L-BMAA in Paenibacillus species By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,781-783DOI: 10.1039/C9TX00203K, ViewpointPeter B. Nunn, Geoffrey A. CoddThe neurotoxic amino acid, 3-N-methyl-2,3-diaminopropanoic acid (BMAA), known in plants of the genus Cycas and in aquatic cyanobacteria and other organisms, is a component of antibiotic peptides in two species of Paenibacillus.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
the Reply to the ‘Comment on “Acetylcysteine in paracetamol poisoning: a perspective of 45 years of use”’ by M. E. Mullins, M. C. Yarema, M. L. A. Sivilotti, M. Thompson, D. A. Algren, M. C. Beuhler and C. P. Holstege, Toxicol. Res., 2019, 8, DOI: 10.1039/C9T By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,1059-1059DOI: 10.1039/C9TX00216B, Comment Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.D. Nicholas Bateman, James W. DearMullins et al. made a comment on our article (DOI: 10.1039/C9TX00002J) stating they noticed the omission of the one-bag, standard concentration protocol which is shared by several centers in North America when we discussed IV acetylcysteine protocols.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
the Biogenic Aspergillus tubingensis silver nanoparticles’ in vitro effects on human umbilical vein endothelial cells, normal human fibroblasts, HEPG2, and Galleria mellonella By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,789-801DOI: 10.1039/C9TX00091G, PaperCristiane Angélica Ottoni, Durvanei Augusto Maria, Priscila Jane Romano de Oliveira Gonçalves, Welington Luiz de Araújo, Ana Olívia de SouzaBiogenic silver nanoparticles are ecofriendly and offers valuable possibilities of applications in several industrial areas.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
the Cadmium telluride quantum dot-exposed human bronchial epithelial cells: a further study of the cellular response by proteomics By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,994-1001DOI: 10.1039/C9TX00126C, PaperYan-Ming Xu, Heng Wee Tan, Wei Zheng, Zhan-Ling Liang, Fei-Yuan Yu, Dan-Dan Wu, Yue Yao, Qiu-Hua Zhong, Rui Yan, Andy T. Y. LauA comparative proteome analysis was conducted to identify global changes in the protein expression profiles of cadmium telluride quantum dot-exposed human bronchial epithelial BEAS-2B cells.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
the Novel evaluation of sevoflurane anesthetic exposure on the testicular germ cells of neonatal male mice By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,988-993DOI: 10.1039/C9TX00193J, PaperAli Raza Ebrahim Soltani, Abdolmohammad Kajbafzadeh, Maryam Ezzati, Zahra Ebrahim Soltani, Navid Hosseinifar, Anahid Maleki, Maryam Nezhad SistaniInhalatory anesthetics may impact spermatogenesis and sexual behavior.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
the Mice with a Sertoli cell-specific knockout of the Ctr1 gene exhibit a reduced sensitivity to cisplatin-induced testicular germ cell apoptosis By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,972-978DOI: 10.1039/C9TX00142E, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Rashin Ghaffari, John H. RichburgExposure to the chemotherapeutic agent cis-diamminedichloroplatinum(II) (cDDP) is well known to instigate acute and prolonged testicular injury in male patients.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
the Astilbin attenuates cerebral ischemia/reperfusion injury by inhibiting the TLR4/MyD88/NF-κB pathway By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,1002-1008DOI: 10.1039/C9TX00222G, PaperJing Li, Zhaowei Gu, Yue Liu, Yu Wang, Min ZhaoIschemic stroke is the second most common cause of death worldwide and cerebral ischemia/reperfusion (I/R) injury also leads to serious tissue damage.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
the Nanoparticle induced barrier function assessment at liquid–liquid and air–liquid interface in novel human lung epithelia cell lines By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,1016-1027DOI: 10.1039/C9TX00179D, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Lars Leibrock, Sandra Wagener, Ajay Vikram Singh, Peter Laux, Andreas LuchTo answer questions about nanoparticle toxicity, translocation and biokinetics following inhalation exposure, in vitro models should have functional barrier properties to mimic the in vivo situation as closely as possible.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
the Application of the direct peptide reactivity assay (DPRA) to inorganic compounds: a case study of platinum species By pubs.rsc.org Published On :: Toxicol. Res., 2019, 8,802-814DOI: 10.1039/C9TX00242A, PaperJocelyn D. C. Hemming, Mark Hosford, Martin M. ShaferThe in chemico Direct Peptide Reactivity Assay (DPRA) was developed as a non-animal, relatively high throughput, screening tool for skin sensitization potential.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article