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Promoting Ideal Cardiovascular Health Through the Life Span




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Growing Evidence for Successful Care Management in Children With Medical Complexity




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Anaerobic Necrotizing Pneumonia: Another Potential Life-threatening Complication of Vaping?

An adolescent girl with a history of frequent electronic cigarette use of nicotine was hospitalized with severe necrotizing pneumonia. Blood cultures obtained before the administration of empirical broad-spectrum intravenous antibiotics had positive results for the growth of Fusobacterium necrophorum. The pathogen is an uncommon but well-known cause of anaerobic pneumonia with unique features that are collectively referred to as Lemierre syndrome or postanginal sepsis. The syndrome begins as a pharyngeal infection. Untreated, the infection progresses to involve the ipsilateral internal jugular vein, resulting in septic thrombophlebitis with direct spread from the neck to the lungs causing multifocal necrotizing pneumonia. The teenager we present in this report had neither a preceding pharyngeal infection nor Doppler ultrasonographic evidence for the presence of deep neck vein thrombi, leading us to explore alternative mechanisms for her pneumonia. We propose the possibility that her behavior of frequent vaping led to sufficient pharyngeal irritation such that F necrophorum colonizing her oropharynx was inhaled directly into her lungs during electronic cigarette use. Preexisting, but not yet recognized, vaping-related lung injury may have also contributed to her risk of developing the infection. The patient was hospitalized for 10 days. At follow-up one month later, she still became short of breath with minimal exertion.




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Eosinophilic Pneumonia and Lymphadenopathy Associated With Vaping and Tetrahydrocannabinol Use

Idiopathic acute eosinophilic pneumonia is a rare and potentially life-threatening condition that is defined by bilateral pulmonary infiltrates and fever in the presence of pulmonary eosinophilia. It often presents acutely in previously healthy individuals and can be difficult to distinguish from infectious pneumonia. Although the exact etiology of idiopathic acute eosinophilic pneumonia remains unknown, an acute hypersensitivity reaction to an inhaled antigen is suggested, which is further supported by recent public health risks of vaping (electronic cigarette) use and the development of lung disease. In this case, a patient with a year-long history of vaping in conjunction with tetrahydrocannabinol cartridge use who was diagnosed with idiopathic acute eosinophilic pneumonia with associated bilateral hilar lymphadenopathy is described.




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Perspectives on Informed Consent Practices for Minimal-Risk Research Involving Foster Youth




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Improving Antibiotic Prescribing for Pediatric Urinary Tract Infections in Outpatient Settings

OBJECTIVES:

To determine if a multicomponent intervention was associated with increased use of first-line antibiotics (cephalexin or sulfamethoxazole and trimethoprim) among children with uncomplicated urinary tract infections (UTIs) in outpatient settings.

METHODS:

The study was conducted at Kaiser Permanente Colorado, a large health care organization with ~127 000 members <18 years of age. After conducting a gap analysis, an intervention was developed to target key drivers of antibiotic prescribing for pediatric UTIs. Intervention activities included development of new local clinical guidelines, a live case-based educational session, pre- and postsession e-mailed knowledge assessments, and a new UTI-specific order set within the electronic health record. Most activities were implemented on April 26, 2017. The study design was an interrupted time series comparing antibiotic prescribing for UTIs before versus after the implementation date. Infants <60 days old and children with complex urologic or neurologic conditions were excluded.

RESULTS:

During January 2014 to September 2018, 2142 incident outpatient UTIs were identified (1636 preintervention and 506 postintervention). Pyelonephritis was diagnosed for 7.6% of cases. Adjusted for clustering of UTIs within clinicians, the proportion of UTIs treated with first-line antibiotics increased from 43.4% preintervention to 62.4% postintervention (P < .0001). The use of cephalexin (first-line, narrow spectrum) increased from 28.9% preintervention to 53.0% postintervention (P < .0001). The use of cefixime (second-line, broad spectrum) decreased from 17.3% preintervention to 2.6% postintervention (P < .0001). Changes in prescribing practices persisted through the end of the study period.

CONCLUSIONS:

A multicomponent intervention with educational and process-improvement elements was associated with a sustained change in antibiotic prescribing for uncomplicated pediatric UTIs.




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Preventing Asthma Emergencies in Schools

Asthma is a significant public health issue, impacting quality of life, morbidity, and health care costs nationally. Stock asthma rescue medication policies authorize school districts to maintain unassigned albuterol and enable trained staff members to administer the medication in response to asthma symptoms, exercise premedication, and asthma emergencies. Stock asthma rescue (or reliever) medication laws serve as an important fail-safe measure. Such laws provide districts with the ability to respond if a student has an asthma emergency at school but either lacks a diagnosis or does not have access to their own medication. As of September 2019, 13 states have enacted either a law or regulation authorizing the stocking of asthma rescue medication in schools: Arizona, Colorado, Georgia, Illinois, Missouri, New Hampshire, New Jersey, New Mexico, Oklahoma, Ohio, Texas, Utah, and West Virginia. Three additional states provide stock albuterol asthma guidelines but do not have legislation: Indiana, New York, and Nebraska. Some states have found that these policies reduce the need for 911 calls and emergency medical services transports as a result of asthma exacerbations. Initial data also demonstrate that these policies reach populations in need and improve health outcomes. This case study will describe the current state of asthma in Illinois, an innovative policy solution to address asthma emergencies in schools, and the steps taken to advocate for stock asthma rescue medication in Illinois. Legislation for stock albuterol in Illinois was signed into law in August 2018.




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STEPP IN: Working Together to Keep Infants Warm in the Perioperative Period

OBJECTIVES:

Reduce postoperative hypothermia by up to 50% over a 12-month period in children’s hospital NICUs and identify specific clinical practices that impact success.

METHODS:

Literature review, expert opinion, and benchmarking were used to develop clinical practice recommendations for maintaining perioperative euthermia that included the following: established euthermia before transport to the operating room (OR), standardized practice for maintaining euthermia on transport to and from the OR, and standardized practice to prevent intraoperative heat loss. Process measures were focused on maintaining euthermia during these time points. The outcome measure was the proportion of patients with postoperative hypothermia (temperature ≤36°C within 30 minutes of a return to the NICU or at the completion of a procedure in the NICU). Balancing measures were the proportion of patients with postoperative temperature >38°C or the presence of thermal burns. Multivariable logistic regression was used to identify key practices that improved outcome.

RESULTS:

Postoperative hypothermia decreased by 48%, from a baseline of 20.3% (January 2011 to September 2013) to 10.5% by June 2015. Strategies associated with decreased hypothermia include >90% compliance with patient euthermia (36.1–37.9°C) at times of OR arrival (odds ratio: 0.58; 95% confidence interval [CI]: 0.43–0.79; P < .001) and OR departure (odds ratio: 0.0.73; 95% CI: 0.56–0.95; P = .017) and prewarming the OR ambient temperature to >74°F (odds ratio: 0.78; 95% CI: 0.62–0.999; P = .05). Hyperthermia increased from a baseline of 1.1% to 2.2% during the project. No thermal burns were reported.

CONCLUSIONS:

Reducing postoperative hypothermia is possible. Key practices include prewarming the OR and compliance with strategies to maintain euthermia at select time points throughout the perioperative period.




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Current Issues in the Treatment of Acne Vulgaris

Acne vulgaris is an extraordinarily common skin condition in adolescents. The mainstays of acne treatment have remained largely unchanged over recent years. In the context of increasing antibiotic resistance worldwide, there is a global movement away from antibiotic monotherapy toward their more restrictive use. Classically reserved for nodulocystic acne, isotretinoin has become the drug of choice by dermatologists for moderate to severe acne. Given the virtually ubiquitous nature of acne in teenagers, there remains an appreciable need for novel therapies. In this article, we will cover the currently used acne treatments, evaluate the issues and data supporting their use, explore the issues of compliance and the mental health implications of acne care, and recommend directions for the field of acne management in adolescents in the years ahead.




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Diagnosis and Management of Polycystic Ovary Syndrome in Adolescents

Polycystic ovary syndrome (PCOS) is a common female reproductive disorder that often manifests during adolescence and is associated with disruptions in health-related quality of life. Prompt evaluation and clinical support after diagnosis may prevent associated complications and optimize overall health management. This article incorporates the most recent evidence and consensus guidelines to provide an updated review of the pathogenesis, clinical presentation, diagnostic evaluation, and management strategies for adolescents with this complex condition. We will review the recent international guidelines on PCOS; because the diagnosis of PCOS remains controversial, management of this condition is inconsistent. In 2019, PCOS remains a common, yet neglected, condition, in part, because of the lack of agreement around both diagnosis and management.




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Primary and Secondary Prevention of Youth Suicide

Youth suicide is a national and global public health crisis. Pediatricians can use primary and secondary prevention strategies to intervene with youth before or after the onset of suicidal behaviors. Universal suicide risk screening programs can be used to identify youth in medical settings who may otherwise pass through the health care setting with undetected suicide risk. Pediatricians are uniquely positioned to help foster resilience in their young patients and equip families of at-risk youth with safety plans and lethal means safety counseling. Pediatricians on the frontlines of this critical public health crisis require education and training in detecting suicide risk, managing those who screen positive, and connecting their patients to much needed mental health interventions and treatments. Evidence-based suicide risk screening and assessment tools, paired with interventions, are feasible and potentially life-saving in the medical setting.




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Big Red Bus school tour reaches over 400 youth

OM Ireland's Creative Arts Team and a group from the US lead a week-long tour into schools and a kids’ club in a housing estate.




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St. Patrick's message still relevant

St. Patrick's Day celebrates the patron saint of Ireland known for bringing Christianity to Ireland. Hundreds of years later, OM Ireland brings the same message.




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OM Sweden and OM Ireland team up over Easter

OM Sweden joined OM Ireland for outreach over the Easter holiday in Carlow town.




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Participants have a plan but rely on God to act

OM Ireland's biggest outreach of the year teaches participants to commit their ways to Him and trust Him to act.




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Move on, move out

A word of encouragement about being mobilised from a native who stayed in-country, yet encourages all to "go into all the world."




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Transformed by love

One Irish family experienced the transforming love of God...one woman at a time.




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Pub prayers for revival

“Looking around that pub at the various people enjoying their tea, I started really thinking about what he’d said,” Hannah remembers. “Praying for revival…In a country that many have come to learn is spiritually dark, have we given up on praying for the people? Has the belief in revival died, or are we still trusting that God can move in a mighty way?”




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The invisible woman

Walvis Bay, Namibia :: Local women attend a challenging discipleship event on board Logos Hope




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Living on a prayer

One Namibian OM worker operates a prayer house—and does so much more.




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Moving powerfully in the lives of teens

On 1 July 350 teens and leaders poured into the University of Queensland, Australia, for five days of fun and discipleship.




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Prayer and the Word of God changes lives

OM worker is amazed to see God change lives, as he peers over his book table on a busy Muslim street in Australia.




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Living out the message of God

Team members of MAP Australia seek to live out the message of the Gospel to all people, no matter how sympathetic or opposed.




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A voice for those who have none

“The climb has taken me far beyond the mountain,” says Canadian Freedom Climber Denise Heppner, who knows that helping even one person makes a difference.




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Visiting orphans

The OM team in Odessa, Ukraine, regularly visits orphanages in the province, bringing love and the good news to children.




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Repairing smiles in the Odessa province

A team of dentists and volunteers recently visited an orphanage in the Odessa province to fix 75 young smiles.




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Easter puppet outreach in Vinnitsa province

In the weeks around Easter, the OM team in Vinnitsa reached out with a gospel puppet show to more than 1,500 people.




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Visitors from far away

International short-term volunteers reach out to an elderly Jewish couple and share comfort from God's Word.




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Over 60 villages and only four churches

OM Ukraine team gets excited about church planting in a northern Odessa province after participating in a Bus4Life outreach in the area.




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Others need to know and get involved

After a trip to repair war damaged churches in the east, construction workers share their experience in order to inspire others to go.




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Live! On Air in Panama

OM Panama team members share on a live radio talk show about the upcoming International Intensive School of Missions.




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Panama begins the process of recovery

After a week of tensions between government and the indigenous inhabitants, Panamá is on the road to recovery.




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The heart of a volunteer

An OM Panama associate volunteers a month of his vacation time to serve the OM team.




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Protection and forgiveness

A man goes from being sought by gangsters to being sought by God.




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A kitchen to transform lives

Lighthouse Ministries builds a kitchen to transform a community in Panama.




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Laughter is a language everybody speaks

Participants from around the world learnt to speak the language of love and laughter during an outreach to the indigenous tribes in Panama.




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Loved and not forgotten

Workers of OM Panama remind young boys with a troubled past that God has a purpose for their lives.




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‘I still have goose bumps’

No challenge is too big for God: “His provision gave me goose bumps,” shared Audrey, from Switzerland, about her journey to OM Panama’s Mission Extreme.




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Young, achingly hip and social media savvy: welcome to the world of Scotland's fashion influencers

Founded by Wendy H Gilmour in 2011, Thankfifi began as a fashion blog and has since grown to cover lifestyle, travel and interiors.




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Be bold this Valentine's Day in colourful lingerie

Compiled by: Antigoni Markitani




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Embrace your curves on Valentine's Day

Compiled by: Antigoni Markitani




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Beautiful floral lingerie for Valentine's Day

Compiled by Antigoni Markitani




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Sultry nightwear for Valentine's Day

Compiled by: Antigoni Markitani




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Mary Quant Exhibition opens at the V&A in London

Words: Abbie Lyall




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Topshop announces vegan footwear collection

Topshop have announced their first ever vegan footwear collection, available from 10th April 2019.




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Fin24.com | More investors keen on Africa

Investment interest in "frontier" African markets - particularly Nigeria and Kenya - is on the rise.




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Fin24.com | Overseas lotteries out of bounds

Consumers who buy European lottery tickets with their credit cards are in contravention of foreign exchange regulations and may be liable to steep levies.




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Fin24.com | Derivatives




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Fin24.com | Private investments

Historically returns are high.




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Fin24.com | The appeal of alternatives

Investors like something different.