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World Bank predicts sharpest decline of remittances to Caribbean

WASHINGTON, CMC – The World Bank has predicted the sharpest decline of remittances to Latin America and the Caribbean, saying that global remittances on a whole are projected to fall by about 20 percent in 2020 due to the economic crisis...




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Haiti receives US$16.1 million in assistance from US to fight COVID-19

PORT AU PRINCE, Haiti, CMC – The Government of Haiti has received funds amounting to US$16.1 million from the United States to help the country respond to the COVID-19 pandemic. The funds from the United States Agency for International...




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Haiti records seventh death from COVID-19

PORT AU PRINCE, Haiti, CMC – The Ministry of Public Health has confirmed that a 20-year-old man has become the seventh person in Haiti to die of the coronavirus (COVID-19). It is urging the population to follow restriction measures, including...




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Trinidad denies breaking US sanctions, shipping oil to Venezuela

PORT OF SPAIN, Trinidad, CMC – Prime Minister Dr Keith Rowley Saturday dismissed as a “dishonest last gasp and gamble of a dangerously delusional woman” a statement by Opposition Leader Kamla Persad Bissessar calling for him...




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Bermuda records seventh COVID-19 death

HAMILTON, Bermuda, CMC –  Bermuda recorded its seventh COVID-19 death on Saturday as Finance Minister Curtis Dickinson announced that he would need to rewrite this year’s budget because of the battering from the global...




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2020 hurricane season will be more active than normal - CSU forecasters

BRIDGETOWN, Barbados, CMC – A few weeks before the official start of the 2020 Atlantic Hurricane Season, forecasters at the US-based Colorado State University are warning that the six-month period will be more active than normal. The CSU...




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Family held for re-entering Belize illegally

BELMOPAN, Belize, CMC – Police Commissioner Chester Williams said there would be “absolutely no room for negotiation” after a family of four, including two minors, were arrested over the last weekend for illegally entering Belize...




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Vincentian students in Jamaica told to pay over US$1,000 to return home

KINGSTOWN, St Vincent, CMC – St Vincent and the Grenadines students in Jamaica wanting to return home amid the coronavirus (COVID-19, including locked borders, must each pay an estimated US$1,3339 for a return flight. In a letter to the...




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Use of antiviral drug in poultry is blamed for drug resistant strains of avian flu




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Lords recommend “passive immunisation” if bird flu reaches UK




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L-Cell Differentiation Is Induced by Bile Acids Through GPBAR1 and Paracrine GLP-1 and Serotonin Signaling

Glucagon-like peptide 1 (GLP-1) mimetics are effective drugs for treatment of type 2 diabetes, and there is consequently extensive interest in increasing endogenous GLP-1 secretion and L-cell abundance. Here we identify G-protein–coupled bile acid receptor 1 (GPBAR1) as a selective regulator of intestinal L-cell differentiation. Lithocholic acid and the synthetic GPBAR1 agonist, L3740, selectively increased L-cell density in mouse and human intestinal organoids and elevated GLP-1 secretory capacity. L3740 induced expression of Gcg and transcription factors Ngn3 and NeuroD1. L3740 also increased the L-cell number and GLP-1 levels and improved glucose tolerance in vivo. Further mechanistic examination revealed that the effect of L3740 on L cells required intact GLP-1 receptor and serotonin 5-hydroxytryptamine receptor 4 (5-HT4) signaling. Importantly, serotonin signaling through 5-HT4 mimicked the effects of L3740, acting downstream of GLP-1. Thus, GPBAR1 agonists and other powerful GLP-1 secretagogues facilitate L-cell differentiation through a paracrine GLP-1–dependent and serotonin-mediated mechanism.




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Rotating night shift work and adherence to unhealthy lifestyle in predicting risk of type 2 diabetes: results from two large US cohorts of female nurses




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Type 2 diabetes: sweetened drinks pose greater risk than other sugary foods




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Type 2 diabetes: 5000 patients to test feasibility of “remission service”




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Rammya Mathew: Liquid diets offer promise, but we still need upstream solutions




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Diabetes: precision approach will improve outcomes, says research director




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Public health leaders slam Boris Johnson over “sin tax” review plan




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Progress in diabetes care has not improved outcomes in US, study finds




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Obesity: raising price of sugary snacks may be more effective than soft drink tax




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Thousands more patients with type 1 diabetes are getting flash glucose devices, data show




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Diabetes technology: specialists are blocking access for some patients, say experts




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Partha Kar: What will the 2020s hold for diabetes care?




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Reds load up for 1,825-mile trip to Arizona

Led by vice president of home clubhouse operations Rick Stowe, who began working for the club in 1981 and became head of the clubhouse in 1997, the Reds have a well-oiled machine with regard to packing up and moving out.




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Get ready to watch: MLB.TV available for 2019

Spring Training is imminent, Opening Day is within sight and the big league season isn't complete for fans without a subscription to MLB.TV. The most comprehensive streaming service in professional sports is now available for the 2019 season.




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All you need to know for Reds Spring Training

Reds Spring Training in Goodyear, Ariz., will feature a new manager in David Bell, a new coaching staff and several new players. Here is what you need to know about 2019 camp.




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Reds' statement on passing of Frank Robinson

Frank Robinson is considered one of the greatest players to ever wear a Cincinnati Reds uniform. His talent and success brought dynamic change to the Reds and to our City.




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Asking price for Realmuto too steep for Reds

One of the best catchers in baseball was available all winter in J.T. Realmuto, and the Reds were very much one of the teams in hot pursuit in trade talks with the Marlins. But on Thursday, it was the Phillies who acquired Realmuto from Miami.




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Loss of Robinson reverberates around MLB

Jon Miller is having trouble believing that baseball legend Frank Robinson is gone. Robinson, 83, passed away Thursday morning.




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Top 10 moments in Frank Robinson's career

Few figures in baseball history have accomplished as much as Frank Robinson. A feared slugger, a World Series champion, a pioneer for minority managers and an ambassador for the game, Robinson had an impact that can be felt in all corners of the sport.




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Reds eye turnaround year after busy winter

Plenty of teams say they will make roster moves in the offseason to improve and then often underwhelm. No one could say that this winter about the Reds, who were arguably the busiest team during the Hot Stove season.




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Puig in different city but keeping personality

Though some Reds fans were disappointed that Billy Hamilton wasn't brought back this season, it didn't take long for Cincinnati to find another dynamic player who also brings flash and unpredictability. That would be outfielder Yasiel Puig.




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Predicting the Reds' Opening Day roster

Here's an early look at how the Reds' 25-man roster could shape up on Opening Day.




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Duke returns to Reds on one-year deal

The Reds made their signing of reliever Zach Duke official on Monday, announcing that they've signed the veteran left-hander to a one-year contract.




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Reds' Spring Training opens to a different feel

It wasn't just that there were new faces when Reds camp opened Tuesday with the reporting of pitchers and catchers for physicals, there was a different vibe that could be felt in the hallways and clubhouse.




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Reds may play Lorenzen in OF during spring

Reds reliever Michael Lorenzen's top priority in Spring Training will be to get innings and prepare himself to pitch in what could be a multitude of roles. However, Lorenzen's offseason workouts also included outfield work and batting practice -- and that could continue in the spring.




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Bell leads new-look Reds into Spring Training

As Reds Spring Training opened with pitchers and catchers reporting for physicals on Tuesday, new manager David Bell was already be tasked with many responsibilities. But there will be one that looms largest. Following five years out of the postseason, including the past four with more than 90 losses, Bell must restore a culture of winning.




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Wood wins arbitration case with Reds

Reds left-hander Alex Wood won his arbitration case over the club on Wednesday. Wood will earn $9.65 million on his one-year contract this season. Cincinnati had offered $8.7 million.




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Reds hope Roark will bring stability to rotation

When the Reds overhauled their rotation with three offseason trades, the first deal brought right-hander Tanner Roark from the Nationals for reliever Tanner Rainey. Observers saw Roark as a solid middle-of-the rotation hurler who is steady and dependable while able to rack up innings.




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Reds looking to use Iglesias in variety of ways

The Reds want to use Raisel Iglesias in the most intense moments, even if that means using someone else in the ninth.




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Disco embraces fresh start after tough end to '18

Reds starting pitcher Anthony DeSclafani hated how his 2018 season ended and didn't need any motivation to make improvements over the winter.




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Garrett impresses with D as Reds shake up PFP

During some Reds pitchers fielding practice, or PFP drills, on Friday, Amir Garrett was playing first base. Alex Wood was at shortstop and Brandon Finnegan was flashing some skills all over the infield.




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Reasons for optimism for each MLB club

On this opening week of Spring Training, all 30 Major League teams have one thing in common: optimism. Here's an optimism cheat sheet for each of them.




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Rule 5 pick Joe back in catcher's gear with Reds

Utility player and Rule 5 selection Connor Joe has been working with the catchers since Reds Spring Training opened. What makes that a little more interesting is that Joe has never caught a game professionally.




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Reds' Top 30 Prospects list

Who do the Reds have in the pipeline? Get scouting reports, video, stats, projected ETAs and more for Cincy's Top 30 Prospects on MLB Pipeline's Prospect Watch.




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The Reds' Spring Training battle to watch

The next five weeks will see lots of shuffling on Major League rosters. Here are the most intriguing positional battles on each of the 30 MLB clubs.




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Reds add Dietrich on Minor League deal

Upon the passing of his physical on Tuesday, the Reds signed infielder/outfielder Derek Dietrich to a Minor League contract with an invitation to big league camp for Spring Training.




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Puig ready to take Cincy by storm: 'I love red'

New Reds outfielder Yasiel Puig has been in camp for about a week, often hitting on his own on the backfields. With the first full-squad workout taking place on Monday, Puig was able to warm up, throw and hit with his teammates.




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Winker unfazed by crowded Reds outfield

Since Jesse Winker suffered a season-ending shoulder injury on July 23, he's gained a lot of company in the corner-outfield spots.




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Why can’t vehicle registration be renewed online?

THE EDITOR, Madam: I arrived at the Constant Spring tax office at 6:05 a.m. on Monday, May 4 to renew my vehicle registration. At that hour, there were already 30 persons ahead of me. Persons related horror stories of spending up to five hours in...




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Still not prepared for COVID-19

THE EDITOR, Madam: How many more will have to suffer? How many more will have to die to end the discrimination often meted out to persons suspected of or confirmed with COVID-19? The novel coronavirus is highly contagious, seems so mysterious, and...