Interview with George A. Stouffer, MD, author of Association of Inpatient vs Outpatient Onset of ST-Elevation Myocardial Infarction With Treatment and Clinical Outcomes

Interview with Michelle M. Mello, JD, PhD, MPhil, author of The Medical Liability Climate and Prospects for Reform

Interview with Joseph B. Muhlestein, MD, author of Effect of Screening for Coronary Artery Disease Using CT Angiography on Mortality and Cardiac Events in High-Risk Patients With Diabetes

Interview with Frank M. Sacks, MD, author of Effects of High vs Low Glycemic Index of Dietary Carbohydrate on Cardiovascular Disease Risk Factors and Insulin Sensitivity

Interview with Seetha Shankaran, MD, author of Effect of Depth and Duration of Cooling on Deaths in the NICU Among Neonates With Hypoxic Ischemic Encephalopathy: A Randomized Clinical Trial

Interview with David M. Nathan, MD, author of Association Between 7 Years of Intensive Treatment of Type 1 Diabetes and Long-term Mortality

Interview with Jon O. Ebbert, MD, MSc, author of Effect of Varenicline on Smoking Cessation Through Smoking Reduction

Interview with Vicky Stergiopoulos, MD, author of Effect of Scattered-Site Housing Using Rent Supplements and Intensive Case Management on Housing Stability Among Homeless Adults With Mental Illness

Interview with Xiaobin Wang, MD, ScD, author of Efficacy of Folic Acid Therapy in Primary Prevention of Stroke Among Adults With Hypertension in China: The CSPPT Randomized Clinical Trial

Interview with Justin B. Dimick, MD, MPH, author of Hospital Credentialing and Privileging of Surgeons: A Potential Safety Blind Spot

Interview with Ezio Bonifacio, PhD, author of Effects of High-Dose Oral Insulin on Immune Responses in Children at High Risk for Type 1 Diabetes: The Pre-POINT Randomized Clinical Trial

Interview with Anne R. Cappola, MD, ScM, author of Subclinical Thyroid Dysfunction and Fracture Risk: A Meta-analysis

Interview with Eve Hill, JD, author of The ADA, Disability, and Identity

Interview with Ellen Wright Clayton, MD, JD , author of Why the Americans With Disabilities Act Matters for Genetics

Interview with Chyke A. Doubeni, MD, MPH, author of Variation in Adenoma Detection Rate and the Lifetime Benefits and Cost of Colorectal Cancer Screening: A Microsimulation Model

JAMA Topic Review: Edward Livingston, MD, FACS, AGAF, Deputy Editor of JAMA, explores how the study by Paulina Salminen, MD, PhD, supports treating appendicitis without surgery

Interview with Deborah A. Levine, MD, MPH, author of Trajectory of Cognitive Decline After Incident Stroke

Interview with Diana W. Bianchi, MD, author of Noninvasive Prenatal Testing and Incidental Detection of Occult Maternal Malignancies

Interview with Harlan M. Krumholz, MD, SM, author of Mortality, Hospitalizations, and Expenditures for the Medicare Population Aged 65 Years or Older, 1999-2013

Interview with Rachel E. Patzer, PhD, MPH, author of Variation in Dialysis Facility Referral for Kidney Transplantation Among Patients With End-Stage Renal Disease in Georgia. This population epidemiology study uses United States Renal Data System data to characterize dialysis facility–level referral for kidney transplant evaluation in Georgia, the US state with the lowest transplantation rates, and patient and facility factors associated with referral and waitlisting.

Interview with Carlos G. Grijalva, MD, MPH, author of Association Between Hospitalization With Community-Acquired Laboratory-Confirmed Influenza Pneumonia and Prior Receipt of Influenza Vaccination

Interview with Elizabeth T. H. Fontham, MPH, DrPH, author of Breast Cancer Screening for Women at Average Risk: 2015 Guideline Update From the American Cancer Society, Nancy L. Keating, MD, MPH, author of New Guidelines for Breast Cancer Screening in US Women, and Evan R. Myers, MD, MPH, author of Benefits and Harms of Breast Cancer Screening: A Systematic Review

Interview with Ahmedin Jemal, DVM, PhD, author of Temporal Trends in Mortality in the United States, 1969-2013

Interview with Ahmedin Jemal, DVM, PhD, author of Temporal Trends in Mortality in the United States, 1969-2013, and J. Michael McGinnis, MD, MPP, author of Mortality Trends and Signs of Health Progress. Also in this episode is a conversation with Christopher J.L. Murray, MD, DPhil, a Professor of Global Health at the University of Washington and Institute Director of the Institute for Health Metrics and Evaluation.

Interview with David A. Asch, MD and Kevin G. Volpp, MD, PhD, authors of Effect of Financial Incentives to Physicians, Patients, or Both on Lipid Levels: A Randomized Clinical Trial

Interview with David Simel, MD, author of Does This Patient With Chest Pain Have Acute Coronary Syndrome? The Rational Clinical Examination Systematic Review

ACS is a common and potentially lethal problem. However, only about 10% of patients who present to an emergency department with chest pain actually have ACS. In this JAMA Clinical Reviews podcast, we discuss which signs, symptoms and tests used to make the diagnosis of ACS are reliable.

Edward H. Livingston MD, speaks with Alexander Fanaroff, MD, author of Does This Patient With Chest Pain Have Acute Coronary Syndrome? The Rational Clinical Examination Systematic Review as well as a patient who was diagnosed with myocardial infarction.

Interview with Lee M. Jampol, MD, author of Panretinal Photocoagulation vs Intravitreous Ranibizumab for Proliferative Diabetic Retinopathy: A Randomized Clinical Trial

Interview with Alex B. Haynes, MD, MPH, author of Relationship Between Cesarean Delivery Rate and Maternal and Neonatal Mortality

Interview with Roger Stupp, MD, author of Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial

Interview with John H. Sampson, MD, PhD, MHSc, MBA, author of Alternating Electric Fields for the Treatment of Glioblastoma

Interview with Debbie A. Lawlor, PhD, author of Live-Birth Rate Associated With Repeat In Vitro Fertilization Treatment Cycles

The 2015-2020 US Dietary Guidelines for Americans were recently released. They are intended to provide guidance for health policy officials and clinicians regarding healthy diets and establishing goals for improving nutrition. These are important since bad eating habits are the underlying cause for a great deal of disease in the US and that these guidelines influence the operations of programs such as school lunch assistance, meals on wheels etc. Because these guidelines influence policy, they have been criticized by various investigators and special interest groups. Karen DeSalvo, MD, Acting Assistant Secretary for Health at HHS and author of Dietary Guidelines for Americans responds to some of these criticisms and explains how the guideline was created and what it is intended to do. Implementation of the guidelines dietary advice may be challenging and Deborah Clegg, RD, PhD, Professor of Internal Medicine at UCLA discusses how the various recommendations can be followed.

Interview with Raj Chetty, PhD, author of The Association Between Income and Life Expectancy in the United States, 2001-2014, and Angus Deaton, PhD, author of On Death and Money: History, Facts, and Explanations

Interview with Kiros Berhane, PhD, author of Association of Changes in Air Quality With Bronchitic Symptoms in Children in California, 1993-2012

Interview with Antoni Ribas, MD, PhD, author of Association of Pembrolizumab With Tumor Response and Survival Among Patients With Advanced Melanoma

Christine Curry, MD, PhD, assistant professor of obstetrics and gynecology at the University of Miami, discusses the challenges of keeping pregnant patients and her colleagues well-informed of the facts as Zika virus fears circulate.

Interview with Gillian L. Booth, MD, author of Association of Neighborhood Walkability With Change in Overweight, Obesity, and Diabetes

Interview with Ann E. Kurth, PhD, RN, MSN, MPH, author of Screening for Syphilis Infection in Nonpregnant Adults and Adolescents: US Preventive Services Task Force Recommendation Statement

Howard Bauchner, MD, Editor in Chief of JAMA, interviews Simon Chapman, MD, author of Association Between Gun Law Reforms and Intentional Firearm Deaths in Australia, 1979-2013

Interview with Barbara E. Murray, MD, author of Infectious Disease Expert Sees Threat From Colistin-Resistant Superbug

Interview with David Grossman, MD, author of Screening for Lipid Disorders in Children and Adolescents: US Preventive Services Task Force Recommendation Statement

Introducing a new series of JAMA articles on professionalism, discussed from the perspective of how clinicians should address challenging clinical situations and adverse events in their medical practice. In the first episode of the accompanying podcast, JAMA Professionalism: Best Practice, we interview Wendy Levinson, MD, and Jensen Yeung, MD, authors of Disclosure of Medical Error, which appeared in the August 16, 2016 issue of JAMA, as well as Thomas H. Gallagher, MD.

Interview with Vivian S. Lee, MD, PhD, MBA;, author of Implementation of a Value-Driven Outcomes Program to Identify High Variability in Clinical Costs and Outcomes: Association With Reduced Cost and Improved Quality, and Michael E. Porter, PhD, author of From Volume to Value in Health Care: The Work Begins

In this episode of JAMA Professionalism: Best Practice, Edward H. Livingston, MD looks at the case of a physician requesting prescription medication from a colleague to examine professional boundaries between physicians and options for managing those boundaries. Shiphra Ginsburg, MD and Wendy Levinson, MD, authors of the related article, join Dr Livingston to discuss the best options for handling this challenging situation. Arthur S. Hengerer, MD, chair of the Federation of State Medical Boards discusses the legal and licensure ramifications of physicians prescribing for other clinicians and Kate E. Engelhardt, MD, and D. Brock Hewitt, MD, MPH, practicing physicians, relate their experience with other clinicians asking them to prescribe medications.

Interview with Christopher JL. Murray, MD, DPhil, author of US County-Level Trends in Mortality Rates for Major Causes of Death, 1980-2014

Interview with Alex R. Kemper, MD, MPH, MS, Task Force member and co-author of Folic Acid Supplementation for the Prevention of Neural Tube Defects: US Preventive Services Task Force Recommendation Statement

Interview with Julie Rani Nangia, BA, MD, author of Effect of a Scalp Cooling Device on Alopecia in Women Undergoing Chemotherapy for Breast Cancer: The SCALP Randomized Clinical Trial, and Hope S. Rugo, MD, author of Association Between Use of a Scalp Cooling Device and Alopecia After Chemotherapy for Breast Cancer

In 2017 the Society for Critical Care Medicine updated its guidelines for sepsis management. These new guidelines differ significantly from ones in the past in that they no longer recommend protocolized resuscitation and emphasize early and aggressive fluid resuscitation when patients present with septic shock. This is the first podcast in the Surviving Sepsis guideline series. The next episode discusses why the new sepsis guideline changed.

Article discussed in this episode: Management of Sepsis and Septic Shock

Speakers:

Laura Evans, MD, MSc, of Bellevue Hospital and NYU Medical Center

Andrew Rhodes, MBBS, MD, of St George’s University Hospitals NHS Trust and co-chair of the Surviving Sepsis guideline panel

Mitchell M. Levy, MD, of the Alpert Medical School of Brown University and Rhode Island Hospital

Recent guidelines for how to best manage septic shock have changed. Gone are recommendations for central venous oxygen saturation monitoring and goal-directed therapy. In is the concept that septic shock be treated as an emergency with rapid administration of antibiotics and large amounts of fluids. Our discussants Derek C. Angus, MD, MPH, and Michael D. Howell, MD, MPH, discuss why these recommendations have changed. This is the second podcast in the Surviving Sepsis guideline series. The first podcast reviewed what recommendations are in the guideline itself.

Article discussed in this episode: Management of Sepsis and Septic Shock

Speakers: JAMA Associate Editor Derek C. Angus, MD, MPH, University of Pittsburgh, and Michael D. Howell, MD, MPH, University of Chicago.