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Development and characterisation of acoustofluidic devices using detachable electrodes made from PCB

Lab Chip, 2020, Advance Article
DOI: 10.1039/C9LC01192G, Paper
Roman Mikhaylov, Fangda Wu, Hanlin Wang, Aled Clayton, Chao Sun, Zhihua Xie, Dongfang Liang, Yinhua Dong, Fan Yuan, Despina Moschou, Zhenlin Wu, Ming Hong Shen, Jian Yang, Yongqing Fu, Zhiyong Yang, Christian Burton, Rachel J. Errington, Marie Wiltshire, Xin Yang
We demonstrate a novel SAW device fabrication technique by mechanically clamping interdigital electrodes (IDEs) on the printed circuit board (PCB) to a LiNbO3 wafer. The novel PCB-SAW device is capable of performing all the functions of standard SAW devices.
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Microfluidic device for high-throughput affinity-based isolation of extracellular vesicles

Lab Chip, 2020, Advance Article
DOI: 10.1039/C9LC01190K, Paper
Ting-Wen Lo, Ziwen Zhu, Emma Purcell, Daniel Watza, Joyful Wang, Yoon-Tae Kang, Shruti Jolly, Deepak Nagrath, Sunitha Nagrath
Immunoaffinity based EV isolation technologies use antibodies targeting surface markers on EVs to provide higher isolation specificity and purity compared to existing approaches.
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A new polymer lab-on-a-chip (LOC) based on a microfluidic capillary flow assay (MCFA) for detecting unbound cortisol in saliva

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00071J, Paper
Vinitha T. U., Sthitodhi Ghosh, Alexander Milleman, Thinh Nguyen, Chong H. Ahn
A new polymer lab-on-a-chip with on-chip dried reagents for microfluidic capillary flow assay (MCFA) detection of unbound cortisol in saliva.
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Spatially isolated reactions in a complex array: using magnetic beads to purify and quantify nucleic acids with digital and quantitative real-time PCR in thousands of parallel microwells

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00069H, Paper
W. Hampton Henley, Nathan A. Siegfried, J. Michael Ramsey
Encoded beads carrying primer pairs for nucleic acid targets are used for sample preparation and multiplexed-in-space digital PCR quantification.
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Multiplexed homogeneous digital immunoassay based on single-particle motion analysis

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00079E, Paper
Kenji Akama, Hiroyuki Noji
Homogeneous digital immunoassay is a powerful analytical method for highly sensitive biomarker detection with a simple protocol. By using this method, we demonstrated the simultaneous multiple protein detection.
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Open sessile droplet viscometer with low sample consumption

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00248H, Paper
Matthias Hermann, Kyle Bachus, Graham T. T. Gibson, Richard D. Oleschuk
This paper reports a portable viscometer that requires less than 10 μL of sample for a measurement.
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In-air EIS sensor for in situ and real-time monitoring of in vitro epithelial cells under air-exposure

Lab Chip, 2020, Advance Article
DOI: 10.1039/C9LC01064E, Paper
Seungbeom Noh, Hanseup Kim
This paper reports in-air monitoring of in vitro monolayer cells under air-exposure utilizing electrochemical impedance spectroscopy (EIS).
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Nanocrystal synthesis, μfluidic sample dilution and direct extraction of single emission linewidths in continuous flow

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00213E, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Ioannis Lignos, Hendrik Utzat, Moungi G. Bawendi, Klavs F. Jensen
We present a flow-based system coupled with an optical interferometry setup for the extraction of single nanocrystal properties.
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Catalytic exchange of hydrogen isotopes intensified by two-phase stratified flow in wettability designable microchannels

Lab Chip, 2020, Accepted Manuscript
DOI: 10.1039/D0LC00250J, Paper
Yuexiao Song, Feng Xin, Yongsheng Xu
This work develops a reliable method to achieve stratified flow in squared cross-section microchannels by endowing the four channel walls with very different wettabilities. The gas–liquid flows are studied experimentally...
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Multiscale brain research on a microfluidic chip

Lab Chip, 2020, 20,1531-1543
DOI: 10.1039/C9LC01010F, Critical Review
Yanan Zhao, Utkan Demirci, Yun Chen, Pu Chen
We report recent progress in applying innovative microfluidic chip-based neurotechnologies to promote multiscale brain research across the hierarchical organizations from the molecular, cellular, and tissue levels up to the whole organism level.
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Microfluidic device to study flow-free chemotaxis of swimming cells

Lab Chip, 2020, 20,1639-1647
DOI: 10.1039/D0LC00045K, Paper
Nicolas Garcia-Seyda, Laurene Aoun, Victoria Tishkova, Valentine Seveau, Martine Biarnes-Pelicot, Marc Bajénoff, Marie-Pierre Valignat, Olivier Theodoly
Permeable agarose barriers allow flow-free gradient generation, applicable to adherent and non-adherent (swimming) cells, as well as co-culture experiments.
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Acoustic erythrocytometer for mechanically probing cell viscoelasticity

Lab Chip, 2020, Advance Article
DOI: 10.1039/C9LC00999J, Paper
Open Access
A. Link, T. Franke
Novel microfluidic platform to determine the viscoelastic fingerprint of a red blood cell population using surface acoustic waves.
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Particle/cell separation using sheath-free deterministic lateral displacement arrays with inertially focused single straight input

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00354A, Paper
Naotomo Tottori, Takasi Nisisako
We propose sheath-free microfluidic deterministic lateral displacement devices with inertially focused single straight input.
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A high-throughput system combining microfluidic hydrogel droplets with deep learning for screening the antisolvent-crystallization conditions of active pharmaceutical ingredient

Lab Chip, 2020, Accepted Manuscript
DOI: 10.1039/D0LC00153H, Paper
Zhening Su, Jinxu He, Peipei Zhou, Lu Huang, Jianhua Zhou
Crystallization of active pharmaceutical ingredients (APIs) is a crucial process in the pharmaceutical industry due to its great impact in drug efficacy. However, conventional approaches for screening the optimal crystallization...
The content of this RSS Feed (c) The Royal Society of Chemistry




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First look of Netaji Subhash Chandra Bose, new debate over his death




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Express newslist: Updates on Draft National Encryption Policy, beef ban and other stories




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Express newslist: Secret letter on Netaji, Bombay HC verdict on sedition and other updates




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Express News list: Hardik surfaces after disappearance, prosecution seeks death penalty for 8 in Mumbai blasts case




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Express Newslist: Modi meets Fortune 500 CEOs, Gujarat announces Rs 1,000 cr package for EW




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Express Newslist: Modi calls IS greatest challenge, Karnataka bandh, Hawala crackdown links to Dawood




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Express Newslist: Narendra Modi at Facebook townhall, SC rejects Somnath Bharti’s bail plea




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Express Newslist: Mob kills man over beef rumours; 7/11 Mumbai blast sentencing




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Express Newslist: Mumbai blasts convict’s confession, India’s reply to Pak at UN, Mahesh Sharma on Dadri lynching




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Express Newslist: MHA’s ‘zero tolerance’ on Dadri Lynching, jawans killed in Kupwara encounter, Khurshid Mahmud Kasuri’s new book,




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Rising intolerance? Indian Express columnists debate




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7th Pay Commission recommendations: All you need to know




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Rs 90 crore: What is common with this figure?




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#ie100: Narendra Modi to Ravish Kumar, the most powerful Indians




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What is Panama Papers? Here is everything you need to know




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[ASAP] POLARIS: Path of Least Action Analysis on Energy Landscapes

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.9b01108




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[ASAP] What Will Computational Modeling Approaches Have to Say in the Era of Atomistic Cryo-EM Data?

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.0c00123




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[ASAP] What Could Go Wrong? A Practical Guide to Single-Particle Cryo-EM: From Biochemistry to Atomic Models

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.9b01178




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[ASAP] Correction of Missing-Wedge Artifacts in Filamentous Tomograms by Template-Based Constrained Deconvolution

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.9b01111




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[ASAP] Live Analysis and Reconstruction of Single-Particle Cryo-Electron Microscopy Data with CryoFLARE

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.9b01102




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[ASAP] Exploring Conformational Space with Thermal Fluctuations Obtained by Normal-Mode Analysis

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.9b01136




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[ASAP] Molecular Perception for Visualization and Computation: The Proxima Library

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.0c00076




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[ASAP] Mechanism-Based Rational Discovery and <italic toggle="yes">In Vitro</italic> Evaluation of Novel Microtubule Stabilizing Agents with Non-Taxol-Competitive Activity

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.9b01133




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[ASAP] Discovery of Ubiquitin-Specific Protease 7 (USP7) Inhibitors with Novel Scaffold Structures by Virtual Screening, Molecular Dynamics Simulation, and Biological Evaluation

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.0c00154




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[ASAP] Ranking Molecules with Vanishing Kernels and a Single Parameter: Active Applicability Domain <italic toggle="yes">Included</italic>

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.9b01075




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[ASAP] Context Aware Data-Driven Retrosynthetic Analysis

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.9b01141




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[ASAP] Nanomaterial Synthesis Insights from Machine Learning of Scientific Articles by Extracting, Structuring, and Visualizing Knowledge

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.0c00199




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[ASAP] Multisolvent Models for Solvation Free Energy Predictions Using 3D-RISM Hydration Thermodynamic Descriptors

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.0c00065




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[ASAP] Augmenting Hit Identification by Virtual Screening Techniques in Small Molecule Drug Discovery

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.0c00113




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[ASAP] Fast Identification of Possible Drug Treatment of Coronavirus Disease-19 (COVID-19) through Computational Drug Repurposing Study

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.0c00179




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[ASAP] Unraveling the Electric Field-Induced Second Harmonic Generation Responses of Stilbazolium Ion Pairs Complexes in Solution Using a Multiscale Simulation Method

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.9b01161




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[ASAP] Matched Molecular Series Analysis for ADME Property Prediction

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.0c00269




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[ASAP] Ranking of Ligand Binding Kinetics Using a Weighted Ensemble Approach and Comparison with a Multiscale Milestoning Approach

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.9b00968




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[ASAP] Computational Insights into Molecular Activation and Positive Cooperative Mechanisms of FFAR1 Modulators

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.0c00030




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PHOTOS: Serena looks ravishing

The tennis legend has dropped a series of photographs on her Instagram page that brings 'message of hope and optimism'.




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Spanish club apologises to Djokovic

Spanish tennis federation released a statement to clarify that tennis players were not allowed to return to courts until May 11, and were only permitted to conduct individual training outside.