Years of sustained and coordinated efforts will be required to contain and reverse the harmful societal effects of the prescription and illicit opioid epidemics, which are intertwined and getting worse, says a new report from the National Academies of Sciences, Engineering, and Medicine.

A new report from the National Academies of Sciences, Engineering, and Medicine outlines how to examine whether specific levels of nutrients or other food substances (NOFSs) can ameliorate the risk of chronic disease and recommends ways to develop dietary reference intakes (DRI) based on chronic disease outcomes.

Halting the opioid epidemic requires aggressive action across multiple dimensions, including informed, active, and determined front-line leadership from health clinicians working in every setting throughout the nation, says a new National Academy of Medicine (NAM) special publication developed at the request of the National Governors Association to assist the nation’s governors as they work with clinicians to counter the opioid crisis.

A new report from the National Academies of Sciences, Engineering, and Medicine offers a framework to guide federal, tribal, state and local agencies, community groups, and other interested and affected parties in making decisions about the Spirit Lake and Toutle River system, near Mount St. Helens in southwest Washington state.

The National Academy of Engineering announced today that the 2018 Charles Stark Draper Prize for Engineering will be awarded to Bjarne Stroustrup.

The Gulf Research Program (GRP) of the National Academies of Sciences, Engineering, and Medicine today announced grant awards for seven new projects totaling $5.3 million.

The Gulf Research Program (GRP) of the National Academies of Sciences, Engineering, and Medicine is collaborating with the Sea Grant Oil Spill Science Outreach Program to convene a series of workshops aimed at improving community preparedness for future oil spills.

In recognition of the need for a national coordinated and collective response to the epidemic of opioid addiction in the U.S., the National Academy of Medicine (NAM), in partnership with the Aspen Institute, launched a public-private partnership made up of more than 35 organizations representing federal, state, and local governments, health systems, associations and provider groups, health education and accrediting institutions, pharmacies, payers, industry, nonprofits, and academia.

Half-facepiece reusable elastomeric respirators are an effective and viable option for protecting health care workers from exposure to airborne transmissible contaminants or infectious agents — for example, influenza virus — during day-to-day work or with a sudden or rapid influx of patients, such as during a public health emergency, says a new report from the National Academies of Sciences, Engineering, and Medicine.

Medications to Treat Opioid Addiction Are Effective and Save Lives, But Barriers Prevent Broad Access and Use, Says New Report

A new report from the National Academies of Sciences, Engineering, and Medicine examines the effects and efficacy of using dispersants in marine oil spill response.

The National Academy of Medicine (NAM) announced today that more than 100 organizations across the U.S. — including community organizations, hospital and medical systems, academia, nonprofits, and health professional societies — have joined NAM in declaring their commitment to reversing national trends in opioid misuse and overdose.

The Gulf Research Program of the National Academies of Sciences, Engineering, and Medicine has announced the nine recipients of its 2019 Science Policy Fellowships.

For her role in transforming a safety net hospital into a national model for high-quality, cost-efficient health care, the National Academy of Medicine today announced Patricia Gabow is the recipient of the 2019 Gustav O. Lienhard Award for Advancement of Health Care.

The National Academy of Medicine today announced Daniel Weinberger is the recipient of the 2019 Rhoda and Bernard Sarnat International Prize in Mental Health, for his fundamental role in elucidating the biological origins and genetic expressions of schizophrenia, and for transforming how clinicians, researchers, and the public understand mental illness.

For severe acute pain due to surgeries and medical conditions, there is a lack of guidance on the appropriate type, strength, and amount of opioid medication that clinicians should prescribe to patients, says a new report from the National Academies of Sciences, Engineering, and Medicine.

The opioid epidemic in the U.S. is driving a simultaneous epidemic of infectious diseases — including HIV, hepatitis C virus (HCV) and bacterial infections, and sexually transmitted infections — but workforce shortages, stigma, and financial and policy barriers are preventing the integration of opioid use disorder (OUD) and infectious disease services, says a new report from the National Academies of Sciences, Engineering, and Medicine.

A new report from the National Academies of Sciences, Engineering, and Medicine finds that there is no risk-free setting for giving birth, whether at home, in a birth center, or in a hospital.

The White House Office of Science and Technology Policy (OSTP) this week requested that the National Academies of Sciences, Engineering, and Medicine rapidly examine the information and data needed to help determine the origins of the novel coronavirus that is causing a global outbreak of respiratory illness.

Formed earlier this month, the National Academies’ Standing Committee on Emerging Infectious Diseases and 21st Century Health Threats was assembled at the request of the White House Office of Science and Technology Policy and the Office of the Assistant Secretary for Preparedness and Response in response to the COVID-19 outbreak.

The recently formed National Academies Standing Committee on Emerging Infectious Diseases and 21st Century Health Threats, assembled at the request of the White House Office of Science and Technology Policy and the U.S. Department of Health and Human Services’ Office of the Assistant Secretary for Preparedness and Response in response to the COVID-19 outbreak, has been providing rapid expert consultations on several topics, such as social distancing and severe illness in young adults.

The recently formed National Academies Standing Committee on Emerging Infectious Diseases and 21st Century Health Threats, assembled at the request of the White House Office of Science and Technology Policy (OSTP) and the U.S. Department of Health and Human Services’ Office of the Assistant Secretary for Preparedness and Response in response to the COVID-19 outbreak, has been providing rapid expert consultations on several topics, such as social distancing and severe illness in young adults.

A new rapid expert consultation from a standing committee of the National Academies of Sciences, Engineering, and Medicine responds to questions from the White House Office of Science and Technology Policy (OSTP) regarding survival of the COVID-19 virus in relation to temperature and humidity and potential for seasonal reduction and resurgence of cases.

A new rapid expert consultation from a standing committee of the National Academies of Sciences, Engineering, and Medicine.

A new rapid expert consultation from a standing committee of the National Academies of Sciences, Engineering, and Medicine responds to questions from the White House Office of Science and Technology Policy (OSTP) regarding the effectiveness of homemade fabric masks to protect others from the viral spread of COVID-19 from potentially contagious asymptomatic or presymptomatic individuals.

Exide begins to remove lead-polluted soil on Monday morning at a house on the 1200 block of La Puerta Street in Boyle Heights.; Credit: Maya Sugarman/KPCC

All five members of the Los Angeles County Board of Supervisors have signed a letter imploring California Gov. Jerry Brown to intervene in the state’s handling of contamination around the Exide Technologies plant in Vernon.

The letter criticizing the state’s “piecemeal approach to an urgent environmental hazard” comes as workers paid for by Exide are removing lead-contaminated topsoil from two homes near the intersection of Olympic and Indiana avenues in L.A. 

Signed Tuesday, the letter asks for “guaranteed state funding to immediately begin testing” at 37 more homes also sampled, but to less specific degrees, during November 2013. In the words of the board, “further testing and remediation of the other 37 homes has not been confirmed and may not begin until at least October 2014 because Exide has not yet agreed to comply with DTSC directives issued last March.”

The supervisors also say the state has “reneged” on its commitments to test for lead inside the homes as well as outside.

The Department of Toxic Substances Control says that the two homes workers are at this week will be cleaned inside and out — even without indoor testing.  The DTSC’s Rizgar Ghazi said Monday that crews will use HEPA filters, vacuums and shampooing equipment on “basically any flat surface” inside the two residences.

Read the L.A. Board of Supervisors’ letter to Gov. Brown here:

http://www.scribd.com/doc/236655733/LA-County-Supervisors-Letter-to-Gov-Brown-8-12-14

This content is from Southern California Public Radio. View the original story at SCPR.org.

If you try to run a program and receive an error stating that the api-ms-win-crt-runtime-l1-1-0.dll DLL is missing from your computer, you can use this guide to restore the missing DLL so that you program works again. [...]

Speaker of the House Nancy Pelosi wears a mask on Capitol Hill on April 30. Members in the House will not return over coronavirus fears but the Senate is scheduled to return on Monday.; Credit: Saul Loeb/AFP via Getty Images

House Speaker Nancy Pelosi and Senate Majority Leader Mitch McConnell, in a rare joint statement on Saturday, declined an offer from the White House to make rapid COVID-19 tests available for Congress.

"Congress is grateful for the Administration's generous offer to deploy rapid COVID-19 testing capabilities to Capitol Hill, but we respectfully decline the offer at this time," Pelosi and McConnell said. "Our country's testing capacities are continuing to scale up nationwide and Congress wants to keep directing resources to the front-line facilities where they can do the most good the most quickly."

McConnell, R-Ky., plans to bring the Senate back into session on Monday, while Pelosi, D-Calif., and House Majority Leader Steny Hoyer, D-Md., said this week the House would not bring representatives back over coronavirus fears.

On Friday, Health and Human Services Secretary Alex Azar said on Twitter that the Trump administration would send three Abbott "point of care testing machines and 1,000 tests for their use" to Capitol Hill.

President Trump on Saturday tweeted: " No reason to turn it down, except politics. We have plenty of testing. Maybe you need a new Doctor over there. Crazy Nancy will use it as an excuse not to show up to work!"

Pelosi and Hoyer said they made the decision based on advice from the Capitol's attending physician, Brian Monahan. "The House physician's view was that there was a risk to members that was one he would not recommend taking," Hoyer said Tuesday.

So far, Rand Paul of Kentucky is the only senator to have tested positive for the coronavirus. In the House, seven members have tested positive or presumed to be positive for the coronavirus.

On Friday, McConnell shared guidelines from Monahan urging lawmakers and staff to maintain six feet of distance, limit the number of people in offices and to wear masks when possible.

Monahan has told Republican leaders that his office does not have the capacity to proactively test all 100 senators and can only test those who are ill, Politico reported.

This content is from Southern California Public Radio. View the original story at SCPR.org.

Supreme Court Justice Ruth Bader Ginsburg, seen in February, has been released from the hospital after treatment for a gallbladder condition.; Credit: Patrick Semansky/AP

After being treated on Tuesday for a gallbladder infection at Johns Hopkins Hospital in Baltimore, Supreme Court Justice Ruth Bader Ginsburg was discharged on Wednesday.

"She is doing well and glad to be home," according to a Supreme Court press release.

The court said over the next few weeks Ginsburg will return to Johns Hopkins Hospital for follow-up outpatient visits, and for a nonsurgical procedure to remove the gallstone.

Ginsburg, 87, participated in a virtual Supreme Court hearing on Wednesday from her hospital room. The justices and lawyers held unique oral argument sessions by phone all week because of the coronavirus pandemic.

Last year Ginsburg underwent three weeks of radiation for a cancerous tumor on her pancreas, and in December she was operated on for lung cancer.

This content is from Southern California Public Radio. View the original story at SCPR.org.

Opera singer Plácido Domingo, shown here speaking in Spain last July, said earlier this month that he tested positive for the coronavirus.; Credit: Ricardo Rubio/Europa Press via Getty Images

Plácido Domingo has been hospitalized because of COVID-19-related complications, according to multiple reports.

He is in stable condition in an Acapulco, Mexico, hospital and will receive medical attention for "as long as the doctors find it necessary until a hoped-for full recovery," a spokesperson for Domingo told Opera News over the weekend.

Domingo's reported hospitalization comes just days after he posted a March 22 message on Facebook revealing that he had tested positive for the disease caused by the coronavirus.

"I feel it is my moral duty to announce that I tested positive for COVID19, also known as the Corona Virus. My family and I are and will remain individually isolated for as long as it is medically necessary. Today we all enjoyed good health, but I presented symptoms of coughing and fever, so I decided to take the test and the result was positive," Domingo said.

Domingo has been one of opera's most reliable and bankable stars and is known for his ability to sing tenor and baritone and in multiple languages, including Italian, English, Russian and Spanish.

Recently, the 79-year-old has been embroiled in controversy as several women accused the Spanish-born singer of sexual misconduct.

On March 10, NPR reported that LA Opera, which Domingo helped establish, announced that its investigation substantiated 10 "inappropriate conduct" claims levied against him dating back to as early as 1986. Domingo resigned as the LA Opera's general director in October.

Prior to that, he withdrew from a production of the Metropolitan Opera's performance of "Macbeth" amid allegations of sexual misconduct.

He has denied the allegations.

Domingo is among a growing list of celebrities who have announced they have tested positive for the coronavirus, including actor Tom Hanks and his wife Rita Wilson, actor Idris Elba, NBA star Kevin Durant, talk show host Andy Cohen and British Prime Minister Boris Johnson.

This content is from Southern California Public Radio. View the original story at SCPR.org.

Tiny arthropods that live in the pores of our faces

We started our new schedule for "AirTalk" this week. With the expansion of "Brand & Martinez" to two hours, we're now on from 11 a.m. to 1 p.m. Friday's Film Week on AirTalk moves into the noon hour.

I’ve been asked many times in the past couple of days how I feel about the shift. My answer is that it’s working out great for our “AirTalk” team.  We still get in at 8 each morning, but now have three hours to prepare our timeliest topics. It also puts us into the noon hour, where we have the chance to connect with folks heading to lunch. 

I know it’s not all good for some listeners, who might have a harder time listening an hour later. There are also, undoubtedly, fans of “The World” who would’ve rather had it stay at noon instead of moving to 2 p.m. I hope you’ll give us a chance in the new slot and that you find the new lineup still fits your schedule. 

If it doesn’t, remember that you can hear all of our local programs online, at the time of your choosing, at www.kpcc.org.

As for the irreplaceable Patt Morrison, she’ll continue to provide her talents to KPCC listeners with regular features and interviews throughout our day. Though I know many fans of Patt are very sad to see her daily program end, I think Patt’s high-profile segments will be a terrific boost to all the other shows where they’ll be heard.

This will make Patt a presence everywhere on our schedule, including “AirTalk,” which is pretty exciting.

This content is from Southern California Public Radio. View the original story at SCPR.org.

So I became obsessed with Spinning.  Not the act itself, but booking a class—  It's so popular at my gym, it fills up instantly!  An 8:30 a.m. class starts taking reservations exactly 26 hours prior—  A digital clock ticks down the seconds—

So I am now setting my alarm the day before at 6:25 a.m. so I can book a bike at exactly 6:30.

 The alarm goes off, I zip downstairs to get my phone with the gym's app, zip back up to get back into bed—  Then, with a scream, at 6:29 a.m., I realize I left my reading glasses downstairs—  The print's too tiny to see—  I sprint back down—  I'm not even in the saddle and my heart rate is up to 150!  But—

Ding!  I'm in!  At 6:31 there are two bikes left, and one is mine, mine, mine!

I arrive the next morning, amped up, even though I have no idea how to spin.  Tonya, our Amazon-like spinning instructress, approaches me.  She asks if I am wearing cycling shoes.  I do not know what those are.  No matter.  She fetches metal toe-holders that look like tiny bear traps.

I'm getting in deep.

All the arriving cyclists are very excited.  They wear cut off shirts and bike pants and backwards caps.  They're a team.  And here we go, cycling, to the B-52's Love Shack.  Tonya exhorts us to greet each other and exchange high-fives.  "Woo hoo!" everyone yells.  I've discovered a cult!  I love it!

 "Go to 70% of your max!" Tonya cries out.  "Play with your edge!"

 I ignore that and just continue at the easiest gear possible.  I'm spinning!  I sing along to the next tune: "Her name is Rio and she dances on the sand!" 

But here's the thing.  I start sweating copiously.  It's ridiculous.  It looks like there's something wrong with me.  My face is dripping, as are arms, hands.  Soon—and I am not making this up—even my bike is sweating.  It's dripping from the handle bars. Oh, the horror.

The next day, my partner shows me an article about this new exercise-induced side effect called Rhabdomyolysis.  Suffered mostly by first-time spinners, it's where overworked muscles strain your kidneys and your pee turns brown.  "I'm amazed you survived!" he said. But I wonder how my poor infected bike is doing. 
So that's it for me.  I went, I spun, I conquered.

Next up? Yoga for nappers.  Lavender pillows -- hold the toe clips.

This content is from Southern California Public Radio. View the original story at SCPR.org.

Frank Romero with one of his French paintings, in his home in the South of France. But every year, he and his wife Sharon throw a big studio sale for Christmas, and you're invited.; Credit: John Rabe

"Live! Life's a banquet and most poor suckers are starving to death!" - Auntie Mame.

Your calendar is filling up, but here are four holiday events you'll want to make room for:

Every year, pioneering Chicano artist Frank Romero and his wife Sharon throw a big studio sale that includes works by a wide group of artists, and a lot of food and drink. It's just as much a party as a sales event, and Frank and the other artists are always there to meet and greet. And now that the couple is spending more time at their home in France, it's a chance for their old friends to catch up with them, so who knows who you'll see from L.A.'s arts community.

RELATED: See Frank's new works - French scenes with an East LA flavor

The Romero Studio annual Christmas party and sale is Saturday, Dec. 6, 6-10pm; and Sunday, Dec. 7, 1-5pm, at Plaza de la Raza, Boathouse Gallery, 3540 North Mission Rd., LA CA 90031 (in Lincoln Park across from the DMV — which BTW is a very good DMV).

Then, on Sunday, Dec. 14, at 4:30pm,  it's the Advent Procession of Lessons and Carols, at St. James Episcopal Church, which a friend describes as "one of the truly beautiful choral events of the season," and the highlight of the Choir of St. James' season. It's free and it's at St. James' Episcopal Church in Koreatown (3903 Wilshire Blvd., Los Angeles 90010).
 

"Auntie Mame," the 1958 Rosalind Russell movie with more quotable quips than a weekend getaway with Oscar Wilde, has become something of a Christmas tradition. It's screening at the American Cinematheque's Egyptian Theatre on Wednesday, Dec. 17, at 7:30. As delightful as this movie is any day of the week on your TV at home, this is a film to be seen in 35mm with a theater full of people reacting to every bon mot and heart-touching moment.

GO INSIDE: The Disney Hall organ, "Hurricane Mama," turns 10

Last year, my husband and I blindly went to Disney Hall for the Holiday Organ Spectacular. We expected some music and a little fun. But it really was spectacular. It's back this year, on Friday, Dec. 19, with organist David Higgs leading the evening from the console of Hurricane Mama.

If you've never seen or heard the organ in person, this is a great evening because Higgs — a teacher as well as master organist — gives you a guided tour of every stop, and every mood the organ can produce, from cathedral-loud to country-church-quiet. At the end of the night, he breaks the audience into parts to sing "The Twelve Days of Christmas," and you may sing as loud as you like.

These are just a few curated selections, but they're just the tip of the iceberg in Southern California; please make your own holiday event recommendations in the comments below. 

This content is from Southern California Public Radio. View the original story at SCPR.org.

Andrew J. West stars in Anna Mastro's "Walter"; Credit: "Walter"

It's always dicey to characterize a major film festival based on the movies you personally see there, because no matter how diligent you try to be, your impression will always be statistically anecdotal.

I'll see perhaps 10 percent of the films at this year's Palm Springs International Film Festival by the time they roll up the red carpets for the final time, added to the 25 or so I'd watched before I got here, owing to the festival's unique programming policies.

Not bad considering there are 190 movies being screened. So I think I've got the feel of things here. I wouldn't want my doctor to diagnose me based on a test with a 35 to 40 percent chance of accuracy, but I'm not a doctor. Instead of "Do no harm," I quote Spencer Tracy to myself. He said the secret to the creative process is to "just look 'em in the eye and tell 'em the truth."

And the truth is, with the exception of a couple of documentaries and a horror movie, virtually every film I've seen at Palm Springs so far shared some obvious characteristics: the Palm Springs International Film Festival loves it some poignancy and affirmation.

I've already commented on "Match," the Patrick Stewart acting showcase, and "Cowboys," a very funny Croatian comedy with cross-currents of seriousness. I may comment later about "Today," Iran's Oscar submission. (It's terrific by the way, a deeply affecting story about a burnt out cab driver who gets yanked into the world of a battered, unwed mother who steps into his cab.)

(Still from "Today” (Emrooz) by Iranian filmmaker Reza Mirkarimi)

I also saw an Anne Hathaway passion project called "Song One" here. I'm not going to write about it because I'm not in the mood to stomp on somebody else's butterfly. Plus the dramedy "1001 Grams" by the splendiferous-ly named Norwegian Bent Hamer, whose deadpan satire is routinely compared to Jacques Tati.

WATCH the official trailer for "1001 Grams," which includes some foreign languages

At their best, these are all movies that want to move the audience to tears before bouncing a ray of hope off the screen at them. At their worst, these movies are about pain in the same way Novocain is. They acknowledge its reality, in order to neutralize it.

Filmmaker Anna Mastro's debut film "Walter" (one of the Palm Springs premieres) fits what seems to be the festival's programming model, too, and is, I think, a really quite appealing little indie film, with the by now familiar mildly magical realist bent.

It's is a story about grief, though one with a screwball premise so that it doesn't quite present that way at first. Walter (portrayed with charisma and nuance by Andrew J. West) is a 20-something slacker, but a very uptight one, with a soldier's commitment to dress and routine.

He still lives with mom (Virginia Madsen, now shifting toward the character actress portion of her career with ease and grace) and has a job one rung above fast food worker on the ladder of success: He's a ticket taker at the local multiplex.

But what the world surely sees as failure, Walter knows to be his cover for a far more important vocation. Walter's father died when he was just 10 years old; ever since the funeral, Walter has realized something we don't: His real job in life is to decide where people go after they die.

His snap judgments secretly send people to heaven or hell ... until a dead guy from Walter's past shows up and demands that Walter determine his fate, and then all hell breaks loose.

It's an odd premise, bordering on the labored, but Mastro and her extremely appealing cast pull it off, in part by wearing their influences on their sleeves. The fingerprints of Wes Anderson are all over this picture, especially in terms of the way shots are framed and music is used, and I was able to identify the pivotal contribution of "Beasts of the Southern Wild" co-composer Dan Romer by ear, long before I noticed his screen credit.

I suppose that's supposed to be a damning criticism of a first-timer, but I don't see it that way. Tarantino aped Scorsese for years and virtually remade a minor Hong Kong gangster picture when he debuted with "Reservoir Dogs."

Spielberg acknowledges his debt to David Lean. Hitchcock's apprenticeship at Germany's UFA film studio resulted in a lifelong visual and thematic debt to the great Expressionist master Fritz Lang.

The question is, what do you do with your influences, how do you make them your own? And Mastro — who has a real gift for casting, pacing a scene and maneuvering her actors easily between farce and seriousness — has her own talents. She understands how Anderson's visual syntax has become a cinematic shorthand for quirk, and she deploys it to that effect, then tells the story at hand.

There are some issues with that story, though. There's a girl in concessions (Leven Rambin) Walter likes, and there's a bully at work. For all its surface oddity, the mechanical underpinnings of "Walter" frequently feel like they belong in an "American Pie" sequel.

And yet this movie won me over. I liked its faith in the movie palace as a place that still vibrates with the marvelous. I found a dream sequence, where Rambin undresses to camera while sprawled on a rich yellow bed of movie house popcorn hilarious and deeply expressive.

But I think my affection for this picture is mostly centered on Mastro and her cast, which includes a standout performance by Justin Kirk as a very grounded ghost and a broad but successful cameo from William H. Macy as Walter's psychiatrist. They're all groping toward something rather grim and real about loss, while doing their best to serve up some laughs and wonder along the way.

It touched me, because it feels kind of wise.

Off-Ramp contributor R.H. Greene, former editor of Boxoffice Magazine, is in Palm Spring this week to cover the 26th Annual Palm Springs International Film Festival. Look for his missives here, and listen Saturday at noon to Off-Ramp, when he'll interview Chaz Ebert about her late husband Roger Ebert's contributions to the film festival circuit.

This content is from Southern California Public Radio. View the original story at SCPR.org.

; Credit: John Rabe

Dear Off-Ramp fans,

What is a blog, after all? Words and images.

And what is a radio story on the web? Words, images, and sound.

Can't they live together in harmony? We say YES.

And with that in mind, we're killing the Off-Ramp blog page.  

But don't fear; we're not cutting back on content: everything that would have found a home here - Marc Haefele's art reviews, recommendations for fun events, etc. -- will now be on the regular web page of the Off-Ramp radio show. 

All the old blog entries will continue to stay on this page as an archive, like Catherine Deneuve's fading vampire lovers in The Hunger.

This content is from Southern California Public Radio. View the original story at SCPR.org.

Supreme Court Justice Ruth Bader Ginsburg poses for the official photo at the Supreme Court in Washington, D.C. in 2018.; Credit: Mandel Ngan/AFP via Getty Images

Supreme Court Justice Ruth Bader Ginsburg underwent non-surgical treatment Tuesday for a benign gallbladder condition, according to a press release from the Supreme Court. She plans to participate in oral arguments from the hospital on Wednesday, according to the release.

In pain on Monday, Ginsburg went to Sibley Memorial Hospital in Washington after hearing the first-ever Supreme Court teleconference of oral arguments. At Sibley, she was diagnosed with acute cholecystitis, a condition in which a gallstone migrates to the cystic duct. She nonetheless participated in arguments from home on Tuesday, but was in enough pain that she went to Johns Hopkins Hospital in Baltimore for treatment of the infected duct later Tuesday.

Doctors not involved in Ginsburg's care said non-surgical treatment typically involves antibiotics and insertion of a tube to drain the infected duct.

Friends said the justice was in good spirits on Tuesday night, and watching the Metropolitan Opera on her iPad.

Ginsburg's emergency treatment coincides with the U.S. Supreme Court's historic live-streaming of its oral arguments in which the justices are participating by telephone because of the coronavirus. According to the court statement, Ginsburg, 87, is "resting comfortably" and plans to participate in oral arguments again on Wednesday when the court considers an important birth control case.

She is expected to remain in the hospital for another day or two.

Last year, Ginsburg completed three weeks of radiation treatment after a cancerous tumor was discovered on her pancreas. It was the fourth time in 20 years that she had been treated for cancer, and the second time in a year. In December 2019, she was operated on for lung cancer.

This content is from Southern California Public Radio. View the original story at SCPR.org.

; Credit: Illustration: Dan Carino

Read the full article at LAist

Physical and occupational therapists carry bags of personal protective equipment on their way to the room of a COVID-19 patient in a Stamford Hospital intensive care unit in Stamford, Conn., on April 24. This "prone team" turns over COVID-19 to help them breathe.; Credit: John Moore/Getty Images

Intensive care teams inside hospitals are rapidly altering the way they care for patients with COVID-19.

The changes range from new protective gear to new treatment protocols aimed at preventing deadly blood clots.

"Things are moving so fast within this pandemic, it's hard to keep up" says Dr. Angela Hewlett, an infectious diseases physician at University of Nebraska Medical Center in Omaha and medical director of the Nebraska Biocontainment Unit. To stay current, she says, ICUs are updating their practices "on an hourly basis."

"We are learning at light speed about the disease," says Dr. Craig Coopersmith , interim director of the critical care center at Emory University. "Things that previously might have taken us years to learn, we're learning in a week or two. Things that might have taken us a month to learn beforehand, we're learning in a day or two."

The most obvious changes involve measures to protect ICU doctors, nurses and staff from the virus.

"There is a true and real probability of infection," says Dr. Tiffany Osborn a critical care specialist at Washington University School of Medicine and Barnes-Jewish Hospital in St. Louis. "You have to think about everything you touch as if it burned."

So ICUs are adapting measures used at special biocontainment units like the one at the University of Nebraska. These units were designed to care for patients affected by bioterrorism or infected with particularly hazardous communicable diseases like SARS and Ebola.

The Nebraska biocontainment unit "received several patients early on in the pandemic who were medically evacuated from the Diamond Princess cruise ship," Hewlett says. But it didn't have enough beds for the large numbers of local patients who began arriving at the University of Nebraska Medical Center.

So the nurses, respiratory therapists and physicians from the biocontainment team have "fanned out and are now working within those COVID units to make sure that all of our principles and protocols are followed there as well," Hewlett says.

Those protocols involve measures like monitoring ICU staff when they remove their protective gear to make sure the virus isn't transmitted, and placing infected patients in negative pressure rooms, which draw air inward, when possible to prevent the virus from escaping.

One of the riskiest ICU procedures is inserting a breathing tube in a COVID-19 patient's airway, which creates a direct path for virus to escape from a patient's lungs. "If you're intubating a patient, that's a much higher risk than, say, going in and doing routine patient care," Hewlett says.

So ICU teams are being advised to add several layers of protection beyond a surgical mask.

Extra personal protective equipment may include an N95 respirator, goggles, a full face shield, a head hood, an impermeable isolation gown and double gloves.

In many ICUs, teams are also placing a clear plastic box or sheet over the patient's head and upper body before inserting the tube. And as a final safety measure, the doctor may guide the tube using a video camera rather than looking directly down a patient's airway.

"It usually takes 30 minutes or so in order to get all of that equipment together, to get all of the right people there," says Dr. Kira Newman, a senior resident physician at UW Medical Center in Seattle. "and that would be a particularly fast intubation."

But most changes in the ICU are in response to an ongoing flood of new information about how COVID-19 affects the body.

There's a growing understanding, for example, that the infection can cause dangerous blood clots to form in many severely ill patients. These clots can kill if they block arteries supplying the lungs or brain. But they also can prevent blood from reaching the kidneys or even a patient's arms and legs.

Clots are a known risk for all ICU patients, Cooperman says, but the frequency and severity appears much greater with COVID-19. "So we're starting them on a higher level of medicine to prevent blood clots and if somebody actually develops blood clots, we have a plan B and a plan C and a plan D," he says.

ICU teams are also recalibrating their approach to ensuring that patients are getting enough oxygen. Early in the pandemic, the idea was to put patients on mechanical ventilator quickly to make sure their oxygen levels didn't fall too far.

But with experience, doctors have found that mechanical ventilators don't seem to work as well for COVID patients as they do for patients with other lung problems. They've also learned that that many COVID-19 patients remain lucid and relatively comfortable even when the oxygen levels in their blood are extremely low.

So many specialists are now recommending alternatives to mechanical ventilation, even for some of the sickest patients. "We're really trying now to not intubate," Osborn says.

Instead, ICU teams are relying on devices that deliver oxygen through the nasal passages, or through a mask that fits tightly over the face. And there's renewed interest in an old technique to help patients breathe. It's called proning.

"Instead of them being on their back, we're turning them on their front," Osborn says. The reason, she says is to open up a part of the lung that is collapsed when a patient is on their back.

This content is from Southern California Public Radio. View the original story at SCPR.org.

The East Bay Municipal Utility District Wastewater Treatment Plant in Oakland, California. Stanford researchers are testing sewage in hopes of tracking the emergence and spread of COVID-19 outbreaks.; Credit: Justin Sullivan/Getty Images

With coronavirus testing still lagging behind targets, many health officials are searching for other ways to assess the spread of the outbreak. One possibility? Looking at what we flush.

SARS-Cov-2 is often spread through sneezes and coughs, but it also leaves the human body through our waste. Scientists around the world are now testing sewage for the virus, using it as a collective sample to measure infection levels among thousands of people.

While the field of "wastewater epidemiology" existed before the coronavirus pandemic began, it's now rapidly expanding in the hope that it can become a front-line public health tool.

"Normally when I tell people I work with poo, they're not super interested," Stephanie Loeb, a post-doctoral researcher at Stanford University, told NPR in an interview over Skype. But, she says: "There's really a lot of information in our waste."

In the basement of a university building, Loeb pulls samples from freezers filled with vials of raw sewage, collected regularly from 25 wastewater treatment plants around California. Each is a snapshot of that community's health.

"It's this perfect mix, you know," says Krista Wigginton, a professor of environmental engineering at the University of Michigan, also working on the Stanford project. "The entire community is putting samples in at the same time."

She says by the time the virus reaches wastewater treatment plants, it's still possible to read its RNA.

"These are virus particles that are mostly intact, but that are no longer infective," Wigginton says. "That's what it looks like at this point."

The idea is that measuring overall virus levels in sewage over time could indicate whether an outbreak is growing or shrinking, potentially showing that trend earlier than patient testing would.

"That's a real-time measurement of what's happening in the community," says Wigginton. "Whereas some other tools we have, like the number of confirmed cases in clinics, sometimes those are delayed by quite a bit of time because people don't go get checked until maybe their illness has progressed by quite a bit."

The approach is already used for other diseases, such as polio. Health officials are working to eradicate polio around the globe and in Israel, an outbreak was spotted early through the wastewater system.

Stanford University isn't the only group working on coronavirus detection in sewage.

"We have a lot of nicknames," says Newsha Ghaeli, co-founder of the start-up Biobot. "I think some of our customers joke around that we're the 'sewer girls.'"

Biobot is currently testing sewage from about 150 communities across the U.S. Originally, the company was using sewage to monitor the opioid crisis, but quickly started offering coronavirus testing.

"It really caught fire," says Ghaeli. "Within ten days, we hit internal capacity."

Ghaeli says in some cities, they've been able to detect coronavirus in sewage the same week the first cases appeared. Other projects in France and the Netherlands have produced similar results.

In a more challenging scientific feat, the team is also working to estimate the number of individuals who have coronavirus in a community, based on the levels found in sewage.

Calculating that depends on knowing how much virus individuals shed, and some people seem to shed for a longer time than others, complicating the math. Other things could also affect the virus levels, such as how long it takes for the wastewater to reach the treatment plant and rainy weather, which causes runoff to flow in the sewage system in some communities, diluting the samples.

"There's a lot of research that needs to be done before we can say this number in wastewater means this many cases in the community," says Wigginton.

The advantage of testing sewage is that it may capture individuals who are less likely to go to a doctor's offices.

"Every person that is using the toilet has a voice," says Mariana Matus, Biobot's other cofounder. "And they can be taken into account for public health resources and prioritization of resources."

While it's still early in the technology's development, some see it being helpful in detecting new waves of the outbreak.

"I think it is potentially a new role that utilities can play," says Doug Yoder, deputy director of the Miami-Dade Water and Sewer Department in Florida, which serves 2.3 million people. "There has been, at the community level, not a whole lot of data about conditions community-wide."

Miami-Dade County has been sending sewage samples to Biobot for six weeks now, which have shown their virus levels going up and down a bit.

"We've seen in a couple instances the virus counts increase by a factor of six," he says. "And then the week following, it went back down. This data may not yet be ready for primetime in terms of community decision-making, but it has potential and promise for being able to see trends."

Health officials are eager for the information, he says, as one more way to gauge what's really happening with their local outbreak.

This content is from Southern California Public Radio. View the original story at SCPR.org.

Audrey Hepburn I am not, but every once in a while, a girl’s gotta go for the gamine look, right? The ankle-length or capri trousers, the ‘50s pink and black color scheme. This is not the ‘’Breakfast at Tiffany’s” Audrey Hepburn, but the 1957 “Funny Face” Audrey, the intellectual beatnik girl who agrees to do a photo modeling shoot for Fred Astaire in exchange for a trip to Paris, where she can to worship at the feet of her “empathicalism” guru, Professor Flostre, who turns out to be just another “mec” on the make.
 
Of course I had to sneak in some commentary in this ensemble: the shirt in sweetheart-pink with stylized black silhouettes of classic runway shapes over the years …  and the shoes, with the pink-and-black face of a sassy manga girl. This one I like. Some of the sex-bomb manga girl illustrations look more like teen boy fantasy porn versions of those classic Keane portraits of solemn-faced, big-eyed children.
 
If you think Meryl Streep was a tough cookie in “The Devil Wears Prada,” check out the original: Kay Thompson and her star turn as the glamorous, tyrannical fashion mag editor in “Funny Face”! [Why do the handbags carried by women in the movies always look empty? Par for the fantasy, I suppose.

The only woman who comes close to achieving the empty handbag is the Queen, who, if rumor is believed, carries only a handkerchief and lipstick and eyeglasses in hers, maybe one or two other items, and on Sunday some money for the church collection plate. I’m convinced she keeps it handy mostly as a prop. Poor lady: it’s always a sedate British-made Launer handbag and she orders four new ones a year. Maybe at least in her imagination she goes online and buys a Stephen Sprouse Louis Vuitton neon graffiti bag, just for the heck of it.]
 
The Harry Potter cast did a little bit about the Queen’s handbag for her 80th birthday:

This content is from Southern California Public Radio. View the original story at SCPR.org.

; Credit: Michelle Lanz/KPCC

Someone just told me that pink and gray were Vassar’s colors. I would say, “Go Vassarettes!” but, one, Vassarette is a line of brassieres, and, two, the Vassar mascot is The Brewer, for the profession of its founder, Matthew Vassar. You go, Seven Sisters girls and guys!

The scarf is one of two I picked up on vacation – for some reason insect themes are big just now. This one has little gray ants marching over a pink field, a reminder of – what? Teamwork? Conformity? Time to call the exterminator? The other scarf, which I’ll wear presently, is the color of a ripe nectarine, with a pattern of vividly colored beetles. Scarabus chic. Dashing, no?

The glittery pink shirt is one more example of that contrast that I like, against the matte gray knit of the sweater (indoor-outdoor wear for L.A. summers, going from AC to Fahrenheit in a flash). Which explains the vast and shady hat – like a veranda on my head!

I was surprised at myself for buying these shoes – silver and bright pink; when would I ever be wearing that? But there they are, slingbacks made by “Emma Hope’s shoes, Regalia for feet,” an irresistible name.

The oval seal with the maker’s name reminded me of the oval seal on shoes made by Rayne, the 19th-century London shoemaker that had shod the women of the royal family for decades (but not the last two generations of those chic ladies: Diana, Princess of Wales, and Katherine, Duchess of Cambridge).

Please don’t blame Rayne for the Queen’s inordinate fondness for platform peeptoe shoes – her mother made her do it. Literally. Those royal ladies – the Queen, her late mother and late sister, Margaret – were quite short, and those shoes boosted their height. But still …

Here is Rayne’s website for a look at some of the glamorous and glorious shoes for feet past and present – including Anna Pavlova’s, prima ballerina assoluta. Mary Quant designed for Rayne. And before you look, that old caution:  If you have to ask how much …  

A pair of Rayne shoes is on my fantasy list for thrift-store finds, along with a Fortuny dress and a wild Schiaparelli hat. I believe, I believe...

This content is from Southern California Public Radio. View the original story at SCPR.org.

Sean‘s pick this week is spider_plot by Moses. Contents Custom Charts Using the Custom Chart Comments Custom Charts My pick this week is also spider_plot which Jiro picked a few months... read more >>