at The HMGB1-RAGE axis modulates the growth of autophagy-deficient hepatic tumors By feeds.nature.com Published On :: 2020-05-07 Full Article
at WTAP and BIRC3 are involved in the posttranscriptional mechanisms that impact on the expression and activity of the human lactonase PON2 By feeds.nature.com Published On :: 2020-05-07 Full Article
at NF-kappa B interacting long noncoding RNA enhances the Warburg effect and angiogenesis and is associated with decreased survival of patients with gliomas By feeds.nature.com Published On :: 2020-05-07 Full Article
at Chromosome 11 open reading frame 30 (C11orf30), calpain small subunit 1 (CAPNS1; CAPN4), signal transducer and activator of transcription 6 (STAT6) and ankyrin repeat domain 27 (ANKRD27) as diagnostic markers for eosinophilic esophagitis (EoE) By feeds.nature.com Published On :: 2014-12-18 Genomewide association studies identified four genes that could serve as diagnostic markers and/or therapeutic targets for EoE. Full Article
at Extending therapeutic protein half-lives via fusion to affibodies with pH-dependent binding to neonatal Fc receptor By feeds.nature.com Published On :: 2014-12-18 Fusing therapeutic proteins to affibodies with pH-dependent binding to neonatal Fc receptor could improve the proteins' half-lives. Full Article
at Dermatophagoides pteronyssinus peptidase 1 (DERP1) By feeds.nature.com Published On :: 2014-12-18 In vitro and rat studies suggest inhibiting the enzymatic activity of house dust mite (HDM) allergens could help treat allergic asthma. Full Article
at Glutathione peroxidase 4 (GPX4) By feeds.nature.com Published On :: 2014-12-18 Mouse studies suggest inhibiting ferroptosis could help treat ischemia/reperfusion injury in the liver and kidney. Full Article
at Cyclin dependent kinase 7 (CDK7); v-myc myelocytomatosis viral related oncogene neuroblastoma derived (MYCN; NMYC) By feeds.nature.com Published On :: 2014-12-18 In vitro and mouse studies suggest THZ1, a covalent CDK7 inhibitor, could help treat neuroblastoma and other cancers driven by MYCN and other c-MYC (MYC)-family oncoproteins. Full Article
at Translational tidbits By feeds.nature.com Published On :: 2014-12-18 Yabao and MRC Technology partner in PD; charities form Neuro-MAP to insource pharma's abandoned compounds; Singapore creates a diagnostic hub; a roundup of public-private partnerships. Full Article
at Translational balance By feeds.nature.com Published On :: 2014-12-18 Moving discoveries from academia to industry requires a delicate balance of risk, reward, skill sets and personalities, according to a translational panel held at BIO-Europe's partnering conference. Full Article
at Neutralizing the negatives of RNAi By feeds.nature.com Published On :: 2014-12-18 The siRNN technology that Solstice licensed from UCSD could take RNAi-based therapies to tissues outside the liver and expand their use to a host of new diseases. Full Article
at Pac1/LIS1 stabilizes an uninhibited conformation of dynein to coordinate its localization and activity By feeds.nature.com Published On :: 2020-04-27 Full Article
at Tissue-resident ductal macrophages survey the mammary epithelium and facilitate tissue remodelling By feeds.nature.com Published On :: 2020-04-27 Full Article
at Myeloid PTEN promotes chemotherapy-induced NLRP3-inflammasome activation and antitumour immunity By feeds.nature.com Published On :: 2020-05-04 Full Article
at In vitro capture and characterization of embryonic rosette-stage pluripotency between naive and primed states By feeds.nature.com Published On :: 2020-05-04 Full Article
at Differentiation of transplanted haematopoietic stem cells tracked by single-cell transcriptomic analysis By feeds.nature.com Published On :: 2020-05-04 Full Article
at FBP1 loss disrupts liver metabolism and promotes tumorigenesis through a hepatic stellate cell senescence secretome By feeds.nature.com Published On :: 2020-05-04 Full Article
at Transcription factors in ferroptotic cell death By feeds.nature.com Published On :: 2020-03-03 Full Article
at MicroRNA binding site polymorphism in inflammatory genes associated with colorectal cancer: literature review and bioinformatics analysis By feeds.nature.com Published On :: 2020-03-23 Full Article
at Oncolytic adenovirus encoding LIGHT (TNFSF14) inhibits tumor growth via activating anti-tumor immune responses in 4T1 mouse mammary tumor model in immune competent syngeneic mice By feeds.nature.com Published On :: 2020-04-20 Full Article
at Immunostimulatory oncolytic virotherapy for multiple myeloma targeting 4-1BB and/or CD40 By feeds.nature.com Published On :: 2020-05-01 Full Article
at UNC5B mediates G2/M phase arrest of bladder cancer cells by binding to CDC14A and P53 By feeds.nature.com Published On :: 2020-05-06 Full Article
at High-purity orbital angular momentum states from a visible metasurface laser By feeds.nature.com Published On :: 2020-04-27 Full Article
at The rise of integrated quantum photonics By feeds.nature.com Published On :: 2020-04-28 Full Article
at Engineering nanomedicines through boosting immunogenic cell death for improved cancer immunotherapy By feeds.nature.com Published On :: 2020-04-21 Full Article
at Cardamonin protects against lipopolysaccharide-induced myocardial contractile dysfunction in mice through Nrf2-regulated mechanism By feeds.nature.com Published On :: 2020-04-21 Full Article
at Nintedanib inhibits keloid fibroblast functions by blocking the phosphorylation of multiple kinases and enhancing receptor internalization By feeds.nature.com Published On :: 2020-04-23 Full Article
at Diabetes downregulates peptide transporter 1 in the rat jejunum: possible involvement of cholate-induced FXR activation By feeds.nature.com Published On :: 2020-04-27 Full Article
at An in vitro Förster resonance energy transfer-based high-throughput screening assay identifies inhibitors of SUMOylation E2 Ubc9 By feeds.nature.com Published On :: 2020-04-27 Full Article
at Compound LM9, a novel MyD88 inhibitor, efficiently mitigates inflammatory responses and fibrosis in obesity-induced cardiomyopathy By feeds.nature.com Published On :: 2020-04-27 Full Article
at Ex vivo pulsed dendritic cell vaccination against cancer By feeds.nature.com Published On :: 2020-05-04 Full Article
at Head-to-head trials in inflammatory bowel disease: past, present and future By feeds.nature.com Published On :: 2020-04-17 Full Article
at Colons or semi-colons: punctuating the regional variation of intestinal microbial–immune interactions By feeds.nature.com Published On :: 2020-04-22 Full Article
at Inducing senescence sensitizes pancreatic tumours to therapies By feeds.nature.com Published On :: 2020-04-28 Full Article
at Universal screening for hepatitis C virus infection should be linked to universal treatment access By feeds.nature.com Published On :: 2020-04-29 Full Article
at Effects of acute and repeated treatment with methocinnamox, a mu opioid receptor antagonist, on fentanyl self-administration in rhesus monkeys By feeds.nature.com Published On :: 2020-05-06 Full Article
at A novel multidimensional reinforcement task in mice elucidates sex-specific behavioral strategies By feeds.nature.com Published On :: 2020-05-06 Full Article
at Cannabinoid CB<sub>2</sub> receptors mediate the anxiolytic-like effects of monoacylglycerol lipase inhibition in a rat model of predator-induced fear By feeds.nature.com Published On :: 2020-05-06 Full Article
at A roadmap for development of neuro-oscillations as translational biomarkers for treatment development in neuropsychopharmacology By feeds.nature.com Published On :: 2020-05-06 Full Article
at Correction: Ketamine metabolites, clinical response, and gamma power in a randomized, placebo-controlled, crossover trial for treatment-resistant major depression By feeds.nature.com Published On :: 2020-05-06 Full Article
at Nesfatin-1 puts the brakes on reward-based feeding By feeds.nature.com Published On :: 2020-05-06 Full Article
at Evaluating the impact of trauma and PTSD on epigenetic prediction of lifespan and neural integrity By feeds.nature.com Published On :: 2020-05-07 Full Article
at Nuclear receptor crosstalk — defining the mechanisms for therapeutic innovation By feeds.nature.com Published On :: 2020-04-17 Full Article
at Author Correction: Insights into parathyroid hormone secretion By feeds.nature.com Published On :: 2020-04-20 Full Article