(Impact Journals LLC) Volume 11, Issue 18 of @Oncotarget Clinical implications of chromatin accessibility assessed by ATAC-seq profiling in human cancers especially in a large patient cohort is largely unknown.

(European Society for Medical Oncology) A study of 4,532 men in the Veneto region of Italy has found that those who were being treated for prostate cancer with androgen-deprivation therapies (ADT) were less likely to develop the coronavirus COVID-19 and, if they were infected, the disease was less severe. The study is published in Annals of Oncology.

(American Association for Cancer Research) Combining intratumoral electroporation of interleukin-12 (IL-12) DNA (tavokinogene telseplasmid, or TAVO) with the immune checkpoint inhibitor pembrolizumab (Keytruda) led to clinical responses in patients with immunologically quiescent advanced melanoma, according to results from a phase II trial.

(Memorial Sloan Kettering Cancer Center) Scientists at the Sloan Kettering Institute have solved the puzzle of how small chromosomes ensure that they aren't skipped over during meiosis, the process that makes sperm and egg.

(Princeton University, Engineering School) New findings about critical cellular structures have upended common assumptions about their formation and composition and provided new insight how molecular machines are built in living cells.

(Impact Journals LLC) Oncotarget Volume 11, Issue 12 reported that the p16 tumor suppressor is coded by CDKN2A and plays an important role during carcinogenesis and tumor progression in numerous tumor entities.

(Luxembourg Institute of Health) Scientists at the Department of Infection and Immunity of the Luxembourg Institute of Health (LIH) revealed a novel mechanism through which the immune system controls autoimmunity and cancer. In the special focus of the researchers were regulatory T cells -- a type of white blood cells that act as a brake on the immune system.

(JAMA Network) Death certificate data were used to compare the rate of opioid-related deaths in the US among cancer survivors with that of the general population from 2006 through 2016. Whether opioid-associated deaths in cancer survivors, who are often prescribed opioids for cancer-related pain, are rising at the same rate as in the general population is unknown.

(University of Helsinki) Mutations in white blood cells can contribute to abnormal immune profile after hematopoietic stem cell transplantation.

(University of Houston) A University of Houston biomedical researcher is developing a new device to treat babies with blood disorders, because current technology is designed for adults. The ability to perform lifesaving leukapheresis safely and effectively in these most vulnerable pediatric patients will significantly increase their access to highly effective cell-based therapies.

The Hong Kong Special Administrative Region (HKSAR) Government welcomes the promulgation of the Meteorological Development Plan ...

Do you know which main gases are contained in the composition of air? Under climate change and global warming, carbon dioxide ...

Monthly weather summary in Hong Kong

The "Online Video Course on Weather Observation" will explain concisely the basic weather observation methods and techniques, such...

Every summer, rainstorms occur in Hong Kong occasionally, leading to loss of property or even casualties.

(Dartmouth College) Expanded Dartmouth awards program gives prizes for 'spec fic' playwriting on what it means to be human in a computerized world.

(University of Córdoba) The University of Cordoba participated in the first shaping of a hydrological model on a basin scale as a global model to advance in world hydrological predictions.

(Paul Scherrer Institute) Researchers at the Paul Scherrer Institute PSI have collaborated with British economists to study how energy consumption by Swiss industry develops depending on energy pricing. To this end, they examined in particular the prices and consumption of both electricity and natural gas over the past decades. One result: For the most part, price increases have only long-term effects on energy consumption.

(DOE/Oak Ridge National Laboratory) Using ORNL's now-decommissioned Titan supercomputer, a team of researchers estimated the combined consequences of many different extreme climate events at the county level, a unique approach that provided unprecedented regional and national climate projections that identified the areas most likely to face climate-related challenges.

(University of Illinois at Urbana-Champaign, News Bureau) University of Illinois classics professor Clara Bosak-Schroeder writes about how the ancient Greeks thought about natural resources and how it is relevant to responding to climate change today.

(Carnegie Mellon University) A new study developed a model of regulation in which the probability of a stricter standard being enacted increased with the proportion of firms in an industry that could meet the standard. The study found that regulations that consider the proportion of firms that can meet the new standard can motivate the development of a new green technology more effectively than regulations that do not consider this factor.

(Bentham Science Publishers) Using a nationally representative sample, the researchers explored racial/ethnic variation in the link between educational attainment and heart disease among American adults.

(American Marketing Association) Nonprofits may better meet their missions by learning to effectively employ the entirety of the marketing mix to attract individuals to available donation opportunities.

(St. Jude Children's Research Hospital) Funding will help expand collaboration across engineering and physical sciences to expand tools for studying pediatric diseases.

(George Mason University) The team's work supports evidence-based decision making, informed by models, to rethink and facilitate hospital operations during the pandemic.

(Michigan Medicine - University of Michigan) Now, as hospitals across the country start to return to doing non-emergency operations that keep their beds full and their books balanced, they need to think carefully about what resources each of those procedures will need as the pandemic continues. A new guide could help them prioritize and plan. Created by poring over seven years' worth of data from 17 common operations in dozens of hospitals, it's available for free for any hospital to use.

(University of Iowa Health Care) A $3.7 million grant from the Centers for Disease Control and Prevention (CDC) has been awarded to the University of Iowa Carver College of Medicine and the David Geffen School of Medicine at UCLA to study ways to reduce the risk of COVID-19 infection among frontline health care workers in hospital emergency departments.

(University of Massachusetts Amherst) As physicians and families know too well, though Alzheimer's disease has been intensely studied for decades, too much is still not known about molecular processes in the brain that cause it. Now researchers at the University of Massachusetts Amherst say new insights from analytic theory and molecular simulation techniques offer a better understanding of amyloid fibril growth and brain pathology.

(The Institute of Medical Science, The University of Tokyo) Understanding the principles of cancer evolution is important in designing a therapeutic strategy. A research group at The Institute of Medical Science, The University of Tokyo (IMSUT) announced a new simulation model that describes various modes of cancer evolution in a unified manner.

(Columbia University School of Engineering and Applied Science) Sharon Di, assistant professor of civil engineering and engineering mechanics, has won a National Science Foundation CAREER Award for her work in the nascent field of autonomous vehicles and shared mobility transportation, areas rapidly being transformed by emerging communications and sensing technologies.

(Rice University) Rice University researchers have discovered a hidden symmetry in the chemical kinetic equations scientists have long used to model and study many of the chemical processes essential for life.

(Keck School of Medicine of USC) A new USC study suggests that temporarily suppressing the body's immune system during the early stages of COVID-19 could help a patient avoid severe symptoms. That's because the research shows that an interaction between the body's two main lines of defense may be causing the immune system to go into overdrive in some patients.

(DOE/Pacific Northwest National Laboratory) Software vulnerabilities are more likely to be discussed on social media before they're revealed on a government reporting site, a practice that could pose a national security threat, according to computer scientists at Pacific Northwest National Laboratory.

(University of Colorado at Boulder) What can researchers do when their mathematical models of the spread of infectious diseases don't match real-world data? One research team is working on a solution.

(Goethe University Frankfurt) According to modern particle physics, matter produced when neutron stars merge is so dense that it could exist in a state of dissolved elementary particles. This state of matter, called quark-gluon plasma, might produce a specific signature in gravitational waves. Physicists at Goethe University Frankfurt and the Frankfurt Institute for Advanced Studies have now calculated this process using supercomputers.

(Cornell University) To help future scientists make sense of what their telescopes are showing them, Cornell University astronomers have developed a spectral field guide for rocky worlds orbiting white dwarf stars.

(University of Massachusetts Lowell) A UMass Lowell researcher investigating how to identify damage in wind turbines before they fail has received $1.4 million to develop a solution.

(Brown University) Strange spots scattered across the moon's nearside where bedrock is conspicuously exposed are evidence of seismic activity set in motion 4.3 billion years ago that could be ongoing today, the researchers say.

(University of British Columbia) Mars had a global magnetic field much earlier -- and much later -- than previously known. Analysis of new satellite data found clear evidence of a magnetic field coming from a lava flow that formed less than 3.7 billion years ago, half a billion years after many people thought the Martian dynamo had ceased. The researchers also detected low-intensity magnetic fields over the Borealis Basin, believed to be one of the oldest features on Mars.

(Northumbria University ) Researchers from Northumbria University have been awarded £1.2m to help advance our understanding of the Sun and its impact on the planets within our solar system.

(Kudos Innovations Ltd) Kudos helps researchers maximize reach and visibility of research by opening up Kudos Pro. The platform helps showcase work to a range of target audiences, supporting researchers in fields where conferences have been cancelled -- and those with COVID-19-relevant work that needs rapid communication. Over 2,000 researchers have already signed up.

(University of California - Irvine) Cyanobacteria living in rocks in Chile's Atacama Desert extract water from the minerals they colonize and, in doing so, change the phase of the material from gypsum to anhydrite. Researchers at the University of California, Irvine and Johns Hopkins University gained verification of this process through experiments, and the work points to possible strategies for humans to stay hydrated in harsh environments.

(King's College London) A study of female astronauts has assessed the risk of blood clots associated with spaceflight.The study, published in Aerospace Medicine and Human Performance, in collaboration with King's College London, the Centre for Space Medicine Baylor College of Medicine, NASA Johnson Space Centre and the International Space University, examines the potential risk factors for developing a blood clot (venous thromboembolism) in space.