se

Polydopamine-assisted one-step modification of nanofiber surfaces with adenosine to tune the osteogenic differentiation of mesenchymal stem cells and the maturation of osteoclasts

By pubs.rsc.org
Published On ::

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/C9BM01990A, Paper
Taufiq Ahmad, Hayeon Byun, Hyeok Jun Shin, Jinkyu Lee, Sajeesh Kumar Madhurakkat Perikamana, Eun Mi Kim, Young Min Shin, Heungsoo Shin
Adenosine and its receptors have emerged as alternative targets to control cellular functions for bone healing.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

se

The potential role of borophene as a radiosensitizer in boron neutron capture therapy (BNCT) and particle therapy (PT)

By pubs.rsc.org
Published On ::

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00318B, Communication
Pengyuan Qi, Qianyuan Chen, Dong Tu, Songhuan Yao, Yupeng Zhang, Jike Wang, Conghua Xie, Chunxu Pan, Hao Peng
The potential role of borophene as a radiosensitizer in PT and BNCT was investigated.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

se

Antibiofilm coatings based on protein-engineered polymers and antimicrobial peptides for preventing implant-associated infections

By pubs.rsc.org
Published On ::

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00155D, Paper
Sergio Acosta, Arturo Ibañez-Fonseca, Conrado Aparicio, J. Carlos Rodríguez-Cabello
Protein-engineered polymers can be used as multivalent platforms for AMP tethering on implant surfaces as cytocompatible coatings with strong antibiofilm properties.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

se

Enhanced nanoparticle accumulation by tumor-acidity-activatable release of sildenafil to induce vasodilation

By pubs.rsc.org
Published On ::

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00466A, Paper
Peng Zhang, Yu Zhang, Xiaoya Ding, Chunsheng Xiao, Xuesi Chen
An efficient strategy to selectively promote nanoparticle accumulation in solid tumors was developed by encapsulating sildenafil in cisplatin-incorporated polymeric micelles.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

se

Near-infrared-persistent luminescence/bioluminescence imaging tracking of transplanted mesenchymal stem cells in pulmonary fibrosis

By pubs.rsc.org
Published On ::

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00063A, Paper
Yuyang Xia, Hongying Bao, Jie Huang, Xiaodi Li, Chenggong Yu, Zhijun Zhang, Haishui Wang
A dual-labeling strategy integrating near-infrared-persistent luminescence and RfLuc-based bioluminescence imaging techniques has been developed to track the transplanted stem cells, deepening the understanding of the role played by stem cells in PF treatment.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

se

Messenger RNA/polymeric carrier nanoparticles for delivery of heme oxygenase-1 gene in the post-ischemic brain

By pubs.rsc.org
Published On ::

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00076K, Paper
Jungju Oh, Sang-Mi Kim, Eun-Hye Lee, Minkyung Kim, Youngki Lee, Seung Hwan Ko, Ji Hoon Jeong, Chang-Hwan Park, Minhyung Lee
Heme oxygenase-1 messenger RNA (HO1-mRNA) was delivered into the post-ischemic brain, using a polymeric carrier. Therapeutic efficacy of HO1-mRNA delivery was compared with that of HO1-plasmid DNA (HO1-pDNA) in ischemia-reperfusion rat models.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

se

Dendritic cells reprogrammed by CEA messenger RNA loaded multi-functional silica nanospheres for imaging-guided cancer immunotherapy

By pubs.rsc.org
Published On ::

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00395F, Communication
Yue Hu, Yuyin Tang, Xiao-Jing Zhang, Xiao-Tong Yang, Ying-Ying Tang, Su Li, Linyu Hu, Peng Chen, Dong Zhu
Multi-functional and hierarchically structured silica nanospheres are rationally designed and fabricated, which encapsulate quantum dots to permit near infrared deep tissue imaging and are loaded with carcinoembryonic antigen messenger RNA (CEAmRNA) to enable stable and abundant antigen expression in DCs.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

se

A photothermal-hypoxia sequentially activatable phase-change nanoagent for mitochondria-targeting tumor synergistic therapy

By pubs.rsc.org
Published On ::

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00003E, Paper
Jia Qu, Dengke Teng, Guoqing Sui, Shihui Guan, Yang Wang, Qimeihui Wang, Yuanqiang Lin, Haitao Ran, Zhigang Wang, Hui Wang
The advantages of PCM@Lip/IT NPs include mitochondrial-targeting, on-demand drug release, and prodrug activation by hypoxia with guidance/monitoring by PA and FL imaging.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

se

Core–shell particles for drug-delivery, bioimaging, sensing, and tissue engineering

By pubs.rsc.org
Published On ::

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/C9BM01872G, Review Article
Ratchapol Jenjob, Treethip Phakkeeree, Daniel Crespy
Core–shell particles offer significant advantages in their use for bioimaging and biosensors.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

se

Sustainable release of vancomycin from micro-arc oxidised 3D-printed porous Ti6Al4V for treating methicillin-resistant Staphylococcus aureus bone infection and enhancing osteogenesis in a rabbit tibia osteomyelitis model

By pubs.rsc.org
Published On ::

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/C9BM01968E, Paper
Teng Zhang, Qingguang Wei, Hua Zhou, Wenhao Zhou, Daoyang Fan, Xinhong Lin, Zehao Jing, Hong Cai, Yan Cheng, Xiaoguang Liu, Weishi Li, Chunli Song, Yun Tian, Nanfang Xu, Yufeng Zheng, Zhongjun Liu
Sustainable release of vancomycin from micro-arc oxidised 3D-printed porous Ti6A14V for treating MRSA bone infection and enhancing osteogenesis.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

se

Self-assembled nucleo-tripeptide hydrogels provide local and sustained doxorubicin release

By pubs.rsc.org
Published On ::

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00134A, Paper
Kiheon Baek, Alexander David Noblett, Pengyu Ren, Laura J. Suggs
Doxorubicin is intercalated within the nanofibril structure of self-assembled nucleo-peptide hydrogels and injection leads to decrease in tumor volume and greater concentration of chemotherapeutic relative to soluble form.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

se

A pH-responsive dissociable mesoporous silica-based nanoplatform enabling efficient dual-drug co-delivery and rapid clearance for cancer therapy

By pubs.rsc.org
Published On ::

Biomater. Sci., 2020, Accepted Manuscript
DOI: 10.1039/D0BM00204F, Paper
Yongju He, Linjie Shao, Ibrahim Usman, Yao Hu, Anqiang Pan, Shuquan Liang, Hui Xu
The dilemma between tumor accumulation and renal clearance has severely limited the efficacy of mesoporous silica-based drug nanocarrier in cancer therapy. Herein, a pH-responsive dissociable mesoporous silica-based nanoplatform with efficient...
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

se

19 F magnetic resonance imaging enabled real-time, non-invasive and precise localization and quantification of the degradation rate of hydrogel scaffolds in vivo

By pubs.rsc.org
Published On ::

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00278J, Paper
Qinghua Li, Zujian Feng, Huijuan Song, Jianhua Zhang, Anjie Dong, Deling Kong, Weiwei Wang, Pingsheng Huang
19 F MRI is able to precisely monitor the localization and quantify the degradation rate of implantable/injectable hydrogels in real-time and noninvasive manner, with no interference of endogenous background signals and limitation of penetration depth.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

se

ZBTB20-mediated titanium particle-induced peri-implant osteolysis by promoting macrophage inflammatory responses

By pubs.rsc.org
Published On ::

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00147C, Paper
Open Access
Junxiong Qiu, Peng Peng, Min Xin, Zhenkang Wen, Zhong Chen, Sipeng Lin, Manyuan Kuang, Yuan Fu, Guibin Fang, Shixun Li, Changchuan Li, Jiaji Mao, Ling Qin, Yue Ding
Aseptic loosening (AL) caused by wear particles released from implant surfaces is one of the main causes for the failure of artificial joints, which is initiated by macrophage inflammatory responses.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

se

A disulfide based low molecular weight gel for the selective sustained release of biomolecules

By pubs.rsc.org
Published On ::

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00508H, Paper
Nitin D. Bansode, Kotagudda Ranganath Sindhu, Chloe Morel, Murielle Rémy, Julien Verget, Claudine Boiziau, Philippe Barthélémy
Constructing biocompatible soft materials via supramolecular approaches remains an important challenge for in vivo applications.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

se

A conductive PEDOT/alginate porous scaffold as a platform to modulate the biological behaviors of brown adipose-derived stem cells

By pubs.rsc.org
Published On ::

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/C9BM02012H, Paper
Boguang Yang, Fanglian Yao, Lei Ye, Tong Hao, Yabin Zhang, Lei Zhang, Dianyu Dong, Wancai Fang, Yan Wang, Xiaoyang Zhang, Changyong Wang, Junjie Li
The development of three-dimensional conductive scaffolds is vital to support the adhesion, proliferation and myocardial differentiation of stem cells in cardiac tissue engineering.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

se

Multifunctional Antibacterial Dental Sealants Suppress Biofilms Derived from Children at High Risk of Caries

By pubs.rsc.org
Published On ::

Biomater. Sci., 2020, Accepted Manuscript
DOI: 10.1039/D0BM00370K, Paper
Maria Salem Ibrahim, Isadora Martini Garcia, Taissa Vila, Abdulrahman A. Balhaddad, Fabricio Mezzomo Collares, Michael D Weir, Huakun Xu, Mary Anne Melo
Dental caries in children is a leading worldwide concern for oral health. Combining antibacterial and remineralizing additives within dental sealants is a promising approach for caries prevention. Saliva contains oral...
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

se

Oral biofilm elimination by combining iron-based nanozymes and hydrogen peroxide-producing bacteria

By pubs.rsc.org
Published On ::

Biomater. Sci., 2020, 8,2447-2458
DOI: 10.1039/C9BM01889A, Paper
Yanqiu Wang, Xinyu Shen, Shang Ma, Qianqian Guo, Wei Zhang, Lu Cheng, Liming Ding, Zhuobin Xu, Jing Jiang, Lizeng Gao
Combining nanozymes and bacteria to eliminate dental biofilms in a mixed-species model.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

se

In situ conversion of rose bengal microbubbles into nanoparticles for ultrasound imaging guided sonodynamic therapy with enhanced antitumor efficacy

By pubs.rsc.org
Published On ::

Biomater. Sci., 2020, 8,2526-2536
DOI: 10.1039/C9BM02046B, Paper
Rui Hou, Xiaolong Liang, Xiaoda Li, Xu Zhang, Xiaotu Ma, Fan Wang
Sonosensitizer microbubbles enhance drug accumulation and the antitumor efficacy of sonodynamic therapy by ultrasound mediated micro to nano conversion.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

se

Biomimic strategies for modulating the interaction between particle adjuvants and antigen-presenting cells

By pubs.rsc.org
Published On ::

Biomater. Sci., 2020, 8,2366-2375
DOI: 10.1039/C9BM02098E, Review Article
Jie Wu, Guanghui Ma
The design strategies of particle adjuvants by mimicking natural pathogens to strengthen their interaction with antigen-presenting cells.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

se

Super-assembled core/shell fibrous frameworks with dual growth factors for in situ cementum–ligament–bone complex regeneration

By pubs.rsc.org
Published On ::

Biomater. Sci., 2020, 8,2459-2471
DOI: 10.1039/D0BM00102C, Paper
Tian Ding, Jianhua Li, Xingshuang Zhang, Lingqian Du, Yang Li, Dengwang Li, Biao Kong, Shaohua Ge
In this work, a super-assembled framework (SAF) was fabricated to achieve sequential delivery of bFGF and BMP-2 for in situ cementum–ligament–bone complex regeneration.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

se

A nanosystem loaded with perfluorohexane and rose bengal coupled upconversion nanoparticles for multimodal imaging and synergetic chemo-photodynamic therapy of cancer

By pubs.rsc.org
Published On ::

Biomater. Sci., 2020, 8,2488-2506
DOI: 10.1039/C9BM02081K, Paper
Hai-yan Wang, Li Hou, Hai-liang Li, Xu Wang, Yang Cao, Bo-yu Zhang, Jing-tao Wang, Shi-jie Wei, Hong-wan Dang, Hai-tao Ran
A novel nanosystem (FURH-PFH-NPs) combined with LIFU and laser irradiation realized multimodal imaging, targeted release of HCPT, UCNPs-RB and synergetic chemo-photodynamic therapy of cancer.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

se

Enhanced selectivity, cellular uptake, and in vitro activity of an intrinsically fluorescent copper–tirapazamine nanocomplex for hypoxia targeted therapy in prostate cancer

By pubs.rsc.org
Published On ::

Biomater. Sci., 2020, 8,2420-2433
DOI: 10.1039/C9BM01905G, Paper
Vera L. Silva, Abdessamad Kaassis, Ashkan Dehsorkhi, Cédrik-Roland Koffi, Maja Severic, Moustafa Abdelhamid, Duuamene Nyimanu, Christopher J. Morris, Wafa’ T. Al-Jamal
Cu(TPZ)2 complex as a promising hypoxia selective cytotoxin in prostate cancer.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

se

Assembly of FN-silk with laminin-521 to integrate hPSCs into a three-dimensional culture for neural differentiation

By pubs.rsc.org
Published On ::

Biomater. Sci., 2020, 8,2514-2525
DOI: 10.1039/C9BM01624D, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Carolina Åstrand, Veronique Chotteau, Anna Falk, My Hedhammar
The functionalized recombinant spider silk protein FN-silk can self-assemble into a 3D microfiber network. When combined with recombinant laminin521 it provides a 3D culture system suitable for expansion of hPSCs and following neural differentiation.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

se

A medical adhesive used in a wet environment by blending tannic acid and silk fibroin

By pubs.rsc.org
Published On ::

Biomater. Sci., 2020, 8,2694-2701
DOI: 10.1039/D0BM00322K, Paper
Xijie Gao, Qiyuan Dai, Longtao Yao, Hua Dong, Qingtao Li, Xiaodong Cao
A medical adhesive called TASK based on polyphenol-gel systems was developed and showed wet-adhesive, stretchable, self-healing and restorable properties.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

se

NIR-emitting semiconducting polymer nanoparticles for in vivo two-photon vascular imaging

By pubs.rsc.org
Published On ::

Biomater. Sci., 2020, 8,2666-2672
DOI: 10.1039/C9BM02063B, Paper
Xiao-Ting Gong, Wenguang Xie, Jing-Jing Cao, Shengxiang Zhang, Kanyi Pu, Hao-Li Zhang
A NIR-emitting TPF probe (NESPN) was prepared using semiconducting polymers and used for continuously monitoring the whole process of ischemic stroke and subsequent reperfusion. This work provides a new and versatile tool for vascular research and diagnosis of vascular diseases.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

se

A thermo-responsive, self-assembling biointerface for on demand release of surface-immobilised proteins

By pubs.rsc.org
Published On ::

Biomater. Sci., 2020, 8,2673-2681
DOI: 10.1039/C9BM01957J, Paper
Angela Saccardo, Mikhail Soloviev, Enrico Ferrari
Engineering of the neuronal SNARE proteins yields chimeric bio-materials that reversibly assemble and disassemble at set temperatures.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

se

Advances in living cell-based anticancer therapeutics

By pubs.rsc.org
Published On ::

Biomater. Sci., 2020, 8,2344-2365
DOI: 10.1039/D0BM00036A, Review Article
He Dong, Xiao Xu, Leikun Wang, Ran Mo
This review summarizes recent advances in the applications of living cells as drug carriers or active drugs for anticancer drug delivery and cancer therapy.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

se

Particle-mediated delivery of frataxin plasmid to a human sensory neuronal model of Friedreich's ataxia

By pubs.rsc.org
Published On ::

Biomater. Sci., 2020, 8,2398-2403
DOI: 10.1039/C9BM01757G, Communication
Ewa Czuba-Wojnilowicz, Serena Viventi, Sara E. Howden, Simon Maksour, Amy E. Hulme, Christina Cortez-Jugo, Mirella Dottori, Frank Caruso
Multilayered particles in gene therapy for Friedreich's ataxia induce a 27 000-fold increase in frataxin gene expression in a patient-derived cell model.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

se

An intelligent vancomycin release system for preventing surgical site infections of bone tissues

By pubs.rsc.org
Published On ::

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00255K, Paper
Yuan Li, Guang Li, Xiaoling Sha, Litao Li, Kuo Zhang, Daohong Liu, Yanfei Hao, Xu Cui, Lei Wang, Hao Wang
An intelligent anti-bacterial system can be constructed on implants during surgery.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

se

A multifunctional metal-biopolymer coordinated double network hydrogel combined with multi-stimulus responsiveness, self-healing, shape memory and antibacterial properties

By pubs.rsc.org
Published On ::

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00425A, Paper
Kun Yan, Feiyang Xu, Chunyu Wang, Yingying Li, Yuanli Chen, Xiufang Li, Zhentan Lu, Dong Wang
A universal, straightforward macroscale assembly technology has been presented for fabrication of polysaccharide-based multifunctional DN gels based on metal coordination chemistry.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

se

A super-stretchable, self-healing and injectable supramolecular hydrogel constructed by a host–guest crosslinker

By pubs.rsc.org
Published On ::

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00290A, Paper
Yang Zhou, Yuanhao Zhang, Zhaobo Dai, Fang Jiang, Jia Tian, Weian Zhang
Supramolecular hydrogels based on host–guest interactions have drawn considerable attention due to their unique properties and promising applications.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

se

A transport system based on a quantum dot-modified nanotracer is genetically and developmentally stable in pregnant mice

By pubs.rsc.org
Published On ::

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00311E, Paper
Open Access
Hye Jin Kim, Ji Sun Park, Se Won Yi, Minyeon Go, Hye-Ryun Kim, Su Jin Lee, Jong Min Park, Dong Hyun Cha, Sung Han Shim, Keun-Hong Park
The use of nanoscale materials (NMs) could cause problems such as cytotoxicity, genomic aberration, but the impacts of NM exposure during pregnancy remain uncharacterized in the context of clinical applications.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

se

Surface engineering of titanium alloy using metal-polyphenol network coating with magnesium ions for improved osseointegration

By pubs.rsc.org
Published On ::

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00566E, Paper
Sangmin Lee, Yun-Young Chang, Jinkyu Lee, Sajeesh Kumar Madhurakkat Perikamana, Eun Mi Kim, Yang-Hun Jung, Jeong-Ho Yun, Heungsoo Shin
Although titanium-based implants are widely used in orthopedic and dental clinics, improved osseointegration at the bone–implant interface is still required.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

se

Serum miRNAs are differentially altered by ethanol and caffeine consumption in rats

By pubs.rsc.org
Published On ::

Toxicol. Res., 2019, 8,842-849
DOI: 10.1039/C9TX00069K, Paper
M. Martinez, I. M. U. Rossetto, R. M. S. Arantes, F. S. N. Lizarte, L. F. Tirapelli, D. P. C. Tirapelli, L. G. A. Chuffa, F. E. Martinez
Alcoholism is a multifactorial disease with high risk for dependence determined by genetic background, environmental factors and neuroadaptations.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

se

Eco-friendly synthesis of glutathione-capped CdTe/CdSe/ZnSe core/double shell quantum dots: their cytotoxicity and genotoxicity effects on Chinese hamster ovary cells

By pubs.rsc.org
Published On ::

Toxicol. Res., 2019, 8,868-874
DOI: 10.1039/C9TX00113A, Paper
Neo Mervyn Monaheng, Sundararajan Parani, Mary Gulumian, Oluwatobi Samuel Oluwafemi
In this work, we report green one-pot synthesis, cytotoxicity and genotoxicity of glutathione-capped CdTe/CdSe/ZnSe heterostructured quantum dots (QDs) using a label-free xCELLigence RTCA system as well as the Cytokinesis Blocked Micronucleus assay.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

se

Comment on “Acetylcysteine in paracetamol poisoning: a perspective of 45 years of use” by D. N. Bateman and J. W. Dear, Toxicol. Res., 2019, 8, 489

By pubs.rsc.org
Published On ::

Toxicol. Res., 2019, 8,1057-1058
DOI: 10.1039/C9TX00158A, Comment
Michael E. Mullins, Mark C. Yarema, Marco L. A. Sivilotti, Margaret Thompson, D. Adam Algren, Michael C. Beuhler, Christopher P. Holstege
We point out an acetylcysteine protocol that a previous article (D. N. Bateman and J. W. Dear, Toxicol. Res., 2019, 8, 489–498) overlooked.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

se

Thyroid endocrine status and biochemical stress responses in adult male Wistar rats chronically exposed to pristine polystyrene nanoplastics

By pubs.rsc.org
Published On ::

Toxicol. Res., 2019, 8,953-963
DOI: 10.1039/C9TX00147F, Paper
Fatemeh Amereh, Akbar Eslami, Simin Fazelipour, Mohammad Rafiee, Mohammad Ismail Zibaii, Mohammad Babaei
At this time, little is known about the long-term effects of micro(nano)plastics on public health. In the present study, early warning signs of thyroid endocrine disruption were noticed in adult Wistar rats from the ingestion of virgin polystyrene nanoparticles.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

se

Reply to the ‘Comment on “Acetylcysteine in paracetamol poisoning: a perspective of 45 years of use”’ by M. E. Mullins, M. C. Yarema, M. L. A. Sivilotti, M. Thompson, D. A. Algren, M. C. Beuhler and C. P. Holstege, Toxicol. Res., 2019, 8, DOI: 10.1039/C9T

By pubs.rsc.org
Published On ::

Toxicol. Res., 2019, 8,1059-1059
DOI: 10.1039/C9TX00216B, Comment
Open Access
D. Nicholas Bateman, James W. Dear
Mullins et al. made a comment on our article (DOI: 10.1039/C9TX00002J) stating they noticed the omission of the one-bag, standard concentration protocol which is shared by several centers in North America when we discussed IV acetylcysteine protocols.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

se

Cadmium telluride quantum dot-exposed human bronchial epithelial cells: a further study of the cellular response by proteomics

By pubs.rsc.org
Published On ::

Toxicol. Res., 2019, 8,994-1001
DOI: 10.1039/C9TX00126C, Paper
Yan-Ming Xu, Heng Wee Tan, Wei Zheng, Zhan-Ling Liang, Fei-Yuan Yu, Dan-Dan Wu, Yue Yao, Qiu-Hua Zhong, Rui Yan, Andy T. Y. Lau
A comparative proteome analysis was conducted to identify global changes in the protein expression profiles of cadmium telluride quantum dot-exposed human bronchial epithelial BEAS-2B cells.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

se

Innovative models for in vitro detection of seizure

By pubs.rsc.org
Published On ::

Toxicol. Res., 2019, 8,784-788
DOI: 10.1039/C9TX00210C, Review Article
Kimberly L. Rockley, Ruth A. Roberts, Michael J. Morton
New technologies offer the opportunity to screen for seizure liability in vitro, avoiding costly failures in preclinical and clinical development.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

se

Novel evaluation of sevoflurane anesthetic exposure on the testicular germ cells of neonatal male mice

By pubs.rsc.org
Published On ::

Toxicol. Res., 2019, 8,988-993
DOI: 10.1039/C9TX00193J, Paper
Ali Raza Ebrahim Soltani, Abdolmohammad Kajbafzadeh, Maryam Ezzati, Zahra Ebrahim Soltani, Navid Hosseinifar, Anahid Maleki, Maryam Nezhad Sistani
Inhalatory anesthetics may impact spermatogenesis and sexual behavior.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

se

Mice with a Sertoli cell-specific knockout of the Ctr1 gene exhibit a reduced sensitivity to cisplatin-induced testicular germ cell apoptosis

By pubs.rsc.org
Published On ::

Toxicol. Res., 2019, 8,972-978
DOI: 10.1039/C9TX00142E, Paper
Open Access
Rashin Ghaffari, John H. Richburg
Exposure to the chemotherapeutic agent cis-diamminedichloroplatinum(II) (cDDP) is well known to instigate acute and prolonged testicular injury in male patients.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

se

Nanoparticle induced barrier function assessment at liquid–liquid and air–liquid interface in novel human lung epithelia cell lines

By pubs.rsc.org
Published On ::

Toxicol. Res., 2019, 8,1016-1027
DOI: 10.1039/C9TX00179D, Paper
Open Access
Lars Leibrock, Sandra Wagener, Ajay Vikram Singh, Peter Laux, Andreas Luch
To answer questions about nanoparticle toxicity, translocation and biokinetics following inhalation exposure, in vitro models should have functional barrier properties to mimic the in vivo situation as closely as possible.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

se

Application of the direct peptide reactivity assay (DPRA) to inorganic compounds: a case study of platinum species

By pubs.rsc.org
Published On ::

Toxicol. Res., 2019, 8,802-814
DOI: 10.1039/C9TX00242A, Paper
Jocelyn D. C. Hemming, Mark Hosford, Martin M. Shafer
The in chemico Direct Peptide Reactivity Assay (DPRA) was developed as a non-animal, relatively high throughput, screening tool for skin sensitization potential.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

se

Franklin Templeton issues apology to Sebi for global chief's remarks

By www.business-standard.com
Published On :: Fri, 08 May 2020 11:13:00 +0530

Stung by the comments made by the global chief, market regulator on Thursday issued a press release defending the new rules it introduced in October last year


Full Article

se

SC's struggles with 'unruly horse' of public policy in foreign awards

By www.business-standard.com
Published On :: Fri, 08 May 2020 11:58:00 +0530

The Nafed-Alimenta judgment shows it might perhaps be time for Parliament to intervene and clarify the notion of public policy in the context of foreign arbitral awards


Full Article

se

US Federal Reserve won't take rates negative, say fund managers, economists

By www.business-standard.com
Published On :: Fri, 08 May 2020 13:40:00 +0530

Fed funds futures, which are a gauge of where markets expect the Fed's benchmark overnight lending rate to be, are now pricing in a slightly negative rate environment beginning in December


Full Article

se

Only 13% of industrial units resume ops after Odisha eases lockdown

By www.business-standard.com
Published On :: Fri, 08 May 2020 17:29:00 +0530

Micro units in the state have not been able to resume operations to catch up with their larger peers


Full Article

se

Gujarat eases labour laws, offers land to firms shifting base from China

By www.business-standard.com
Published On :: Fri, 08 May 2020 20:28:00 +0530

The state government also offered land and infrastructure for companies and projects that were looking to shift base from China to other destinations


Full Article