ar Analyses of breakpoint junctions of complex genomic rearrangements comprising multiple consecutive microdeletions by nanopore sequencing By feeds.nature.com Published On :: 2020-04-30 Full Article
ar Genome-wide association study identifies zonisamide responsive gene in Parkinson’s disease patients By feeds.nature.com Published On :: 2020-05-01 Full Article
ar Bioinformatic prediction of potential T cell epitopes for SARS-Cov-2 By feeds.nature.com Published On :: 2020-05-06 Full Article
ar The Low-Yield Nuclear Warhead: A Dangerous Weapon Based on Bad Strategic Thinking By feedproxy.google.com Published On :: Jan 28, 2020 Jan 28, 2020In the unintuitive world of nuclear weapons strategy, it’s often difficult to identify which decisions can serve to decrease the risk of a devastating nuclear conflict and which might instead increase it. Such complexity stems from the very foundation of the field: Nuclear weapons are widely seen as bombs built never to be used. Historically, granular—even seemingly mundane—decisions about force structure, research efforts, or communicated strategy have confounded planners, sometimes causing the opposite of the intended effect. Full Article
ar Accumulating Evidence Using Crowdsourcing and Machine Learning: A Living Bibliography about Existential Risk and Global Catastrophic Risk By feedproxy.google.com Published On :: Feb 3, 2020 Feb 3, 2020The study of existential risk — the risk of human extinction or the collapse of human civilization — has only recently emerged as an integrated field of research, and yet an overwhelming volume of relevant research has already been published. To provide an evidence base for policy and risk analysis, this research should be systematically reviewed. In a systematic review, one of many time-consuming tasks is to read the titles and abstracts of research publications, to see if they meet the inclusion criteria. The authors show how this task can be shared between multiple people (using crowdsourcing) and partially automated (using machine learning), as methods of handling an overwhelming volume of research. Full Article
ar The Need for Creative and Effective Nuclear Security Vulnerability Assessment and Testing By feedproxy.google.com Published On :: Feb 10, 2020 Feb 10, 2020Realistic, creative vulnerability assessment and testing are critical to finding and fixing nuclear security weaknesses and avoiding over-confidence. Both vulnerability assessment and realistic testing are needed to ensure that nuclear security systems are providing the level of protection required. Systems must be challenged by experts thinking like adversaries, trying to find ways to overcome them. Effective vulnerability assessment and realistic testing are more difficult in the case of insider threats, and special attention is needed. Organizations need to find ways to give people the mission and the incentives to find nuclear security weaknesses and suggest ways they might be fixed. With the right approaches and incentives in place, effective vulnerability assessment and testing can be a key part of achieving and sustaining high levels of nuclear security. Full Article
ar The Risks and Rewards of Emerging Technology in Nuclear Security By feedproxy.google.com Published On :: Feb 10, 2020 Feb 10, 2020Nuclear security is never finished. Nuclear security measures for protecting all nuclear weapons, weapons-usable nuclear materials, and facilities whose sabotage could cause disastrous consequences should protect against the full range of plausible threats. It is an ongoing endeavor that requires constant assessment of physical protection operations and reevaluation of potential threats. One of the most challenging areas of nuclear security is how to account for the impact–positive and negative—of non-nuclear emerging technologies. The amended Convention on the Physical Protection of Nuclear Material (amended CPPNM) states it should be reviewed in light of the prevailing situation, and a key part of the prevailing situation is technological evolution. Therefore, the upcoming review conference in 2021, as well as any future review conferences, should examine the security threats and benefits posed by emerging technologies. Full Article
ar The Past and Potential Role of Civil Society in Nuclear Security By feedproxy.google.com Published On :: Feb 10, 2020 Feb 10, 2020Civil society has played a very important role in nuclear security over the years, and its role could be strengthened in the future. Some nuclear organizations react against the very idea of civil society involvement, thinking of only one societal role—protesting. In fact, however, civil society has played quite a number of critical roles in nuclear security over the years, including highlighting the dangers of nuclear terrorism; providing research and ideas; nudging governments to act; tracking progress and holding governments and operators accountable; educating the public and other stakeholders; promoting dialogue and partnerships; helping with nuclear security implementation; funding initial steps; and more. Funding organizations (both government and non-government) should consider ways to support civil society work and expertise focused on nuclear security in additional countries. Rather than simply protesting and opposing, civil society organizations can help build more effective nuclear security practices around the world. Full Article
ar Assessing Progress on Nuclear Security Action Plans By feedproxy.google.com Published On :: Feb 10, 2020 Feb 10, 2020Participants at the final Nuclear Security Summit in 2016 agreed on “action plans” for initiatives they would support by five international organizations and groups—the International Atomic Energy Agency, the Global Initiative to Combat Nuclear Terrorism, INTERPOL, the United Nations, and the Global Partnership Against the Spread of Weapons and Materials of Destruction. These institutions were supposed to play key roles in bolstering ongoing nuclear security cooperation after the summit process ended. The action plans were modest documents, largely endorsing activities already underway, and there have been mixed results in implementing them. To date, these organizations have not filled any substantial part of the role once played by the nuclear security summits. Full Article
ar Arms Control Agreement With Russia Should Cover More Than Nuclear Weapons By feedproxy.google.com Published On :: Feb 23, 2020 Feb 23, 2020With the Russia investigation and impeachment behind him, President Trump finally may feel empowered to engage with Russian President Vladimir Putin and pursue an arms control deal. Full Article
ar Secrecy, Public Relations and the British Nuclear Debate By feedproxy.google.com Published On :: Mar 5, 2020 Mar 5, 2020The opening of the British archives has seen historians uncover the secrets of the UK's nuclear weapons programme since the 1990s. While a growing number have sought to expose these former secrets, there has been less effort to consider government secrecy itself. What was kept a secret, when and why? And how and why, notably from the 1980s, did the British government decide to officially disclose greater information about the British nuclear weapons programme to Members of Parliament, journalists, defence academics and the tax-paying general public. Full Article
ar Public Testimony on Trump Administration Funding for Nuclear Theft Preventing Programs By feedproxy.google.com Published On :: Mar 31, 2020 Mar 31, 2020A nuclear explosion detonated anywhere by a terrorist group would be a global humanitarian, economic, and political catastrophe. The current COVID-19 pandemic reminds us not to ignore prevention of and preparation for low-probability, high-consequence disasters. For nuclear terrorism, while preparation is important, prevention must be the top priority. The most effective strategy for keeping nuclear weapons out of the hands of terrorists is to ensure that nuclear materials and facilities around the world have strong and sustainable security. Every president for more than two decades has made strengthening nuclear security around the globe a priority. This includes the Trump administration, whose 2018 Nuclear Posture Review states: “[n]uclear terrorism remains among the most significant threats to the security of the United States, allies, and partners.” Full Article
ar Living with Uncertainty: Modeling China's Nuclear Survivability By feedproxy.google.com Published On :: Apr 11, 2020 Apr 11, 2020A simplified nuclear exchange model demonstrates that China’s ability to launch a successful nuclear retaliatory strike in response to an adversary’s nuclear first strike has been and remains far from assured. This study suggests that China’s criterion for effective nuclear deterrence is very low. Full Article
ar Poll: What the American Public Likes and Hates about Trump's Nuclear Policies By feedproxy.google.com Published On :: Apr 27, 2020 Apr 27, 2020The authors conducted a study which highlights how the U.S. public as a whole and various demographic groups view President Donald Trump's positions on nuclear weapons. Full Article
ar Maxwell Taylor's Cold War: From Berlin to Vietnam By feedproxy.google.com Published On :: May 6, 2020 May 6, 2020Nathaniel Moir reviews Maxwell Taylor's Cold War: From Berlin to Vietnam by Ingo Trauschweizer. Full Article
ar The Value of Carbon Capture, Utilization, and Sequestration By feedproxy.google.com Published On :: Mar 4, 2020 Mar 4, 2020Growing concern around climate change has ignited recent interest in carbon capture, utilization, and storage (CCUS) technologies and generated a series of studies on its global market potential. Full Article
ar Illuminating Homes with LEDs in India: Rapid Market Creation Towards Low-carbon Technology Transition in a Developing Country By feedproxy.google.com Published On :: Mar 19, 2020 Mar 19, 2020This paper examines a recent, rapid, and ongoing transition of India's lighting market to light emitting diode (LED) technology, from a negligible market share to LEDs becoming the dominant lighting products within five years, despite the country's otherwise limited visibility in the global solid-state lighting industry. Full Article
ar How Digital Service Teams are Responding to Covid-19 By feedproxy.google.com Published On :: Mar 31, 2020 Mar 31, 2020David Eaves writes that the most significant lesson coming out of the COVID-19 crisis is the importance of having a digital strategy and a technological infrastructure in place at both the national and local levels. Full Article
ar China and America Are Failing the Pandemic Test By feedproxy.google.com Published On :: Apr 2, 2020 Apr 2, 2020All national leaders must put their countr's interests first, but the important question is how broadly or narrowly they define those interests. Both China and the US are responding to COVID-19 with an inclination toward short-term, zero-sum approaches, and too little attention to international institutions and cooperation. Full Article
ar Exploring the cost-effectiveness of child dental caries prevention programmes. Are we comparing apples and oranges? By feeds.nature.com Published On :: 2020-03-27 Full Article
ar ART with high viscosity GIC and composite restorations in class II cavities: can they thrive in the post-amalgam era? By feeds.nature.com Published On :: 2020-03-27 Full Article
ar Tooth loss in Periodontitis: how valuable are the predictors? By feeds.nature.com Published On :: 2020-03-27 Full Article
ar Fluoride varnish and dental caries in preschoolers: a systematic review and meta-analysis By feeds.nature.com Published On :: 2020-03-27 Full Article
ar Dental caries experience, care index and restorative index in children with learning disabilities and children without learning disabilities: a systematic review and meta-analysis By feeds.nature.com Published On :: 2020-03-27 Full Article
ar How do we decide? Knowledge? Experience? Research? By feeds.nature.com Published On :: 2020-03-27 Full Article
ar How many implants are necessary to stabilise an implant-supported maxillary overdenture? By feeds.nature.com Published On :: 2020-03-27 Full Article
ar Why Matter Matters: How Technology Characteristics Shape the Strategic Framing of Technologies By feedproxy.google.com Published On :: Nov 13, 2019 Nov 13, 2019The authors investigate how the executives of the two largest research institutes for photovoltaic technologies — the National Renewable Energy Laboratory (NREL) in Golden, USA and the Fraunhofer Institute for Solar Energy Systems (Fraunhofer ISE) in Freiburg, Germany — have made use of public framing to secure funding and shape the technological development of solar photovoltaic (PV) technologies. The article shows that the executives used four framing dimensions (potential, prospect, performance, and progress) and three framing tactics (conclusion, conditioning, and concession), and that the choice of dimensions and tactics is tightly coupled to the characteristics of the specific technologies pursued by the research institutes. Full Article
ar Why the U.S. Withdrawal from the Paris Climate Accord is a Mistake By feedproxy.google.com Published On :: Dec 4, 2019 Dec 4, 2019The authors explain why the Trump administration's reiteration of its intent to finalize U.S. withdrawal from the Paris Agreement is a tragic mistake that will weaken us as a nation. Full Article
ar How Clean is the U.S. Steel Industry? An International Benchmarking of Energy and CO2 Intensities By feedproxy.google.com Published On :: Dec 10, 2019 Dec 10, 2019In this report, the authors conduct a benchmarking analysis for energy and CO2 emissions intensity of the steel industry among the largest steel-producing countries. Full Article
ar Study Group on Energy Innovation and the Transition to a Low-Carbon Economy: Advising Fortune 500 Companies By feedproxy.google.com Published On :: Feb 19, 2020 Feb 19, 2020This study group will explore the role of the private sector in evolving energy systems, and how corporations might change in a climate constrained world. Full Article
ar The Value of Carbon Capture, Utilization, and Sequestration By feedproxy.google.com Published On :: Mar 4, 2020 Mar 4, 2020Growing concern around climate change has ignited recent interest in carbon capture, utilization, and storage (CCUS) technologies and generated a series of studies on its global market potential. Full Article
ar Geopolitical and Market Implications of Renewable Hydrogen: New Dependencies in a Low-Carbon Energy World By feedproxy.google.com Published On :: Mar 4, 2020 Mar 4, 2020To accelerate the global transition to a low-carbon economy, all energy systems and sectors must be actively decarbonized. While hydrogen has been a staple in the energy and chemical industries for decades, renewable hydrogen is drawing increased attention today as a versatile and sustainable energy carrier with the potential to play an important piece in the carbon-free energy puzzle. Countries around the world are piloting new projects and policies, yet adopting hydrogen at scale will require innovating along the value chains; scaling technologies while significantly reducing costs; deploying enabling infrastructure; and defining appropriate national and international policies and market structures. What are the general principles of how renewable hydrogen may reshape the structure of global energy markets? What are the likely geopolitical consequences such changes would cause? A deeper understanding of these nascent dynamics will allow policy makers and corporate investors to better navigate the challenges and maximize the opportunities that decarbonization will bring, without falling into the inefficient behaviors of the past. Full Article
ar Illuminating Homes with LEDs in India: Rapid Market Creation Towards Low-carbon Technology Transition in a Developing Country By feedproxy.google.com Published On :: Mar 19, 2020 Mar 19, 2020This paper examines a recent, rapid, and ongoing transition of India's lighting market to light emitting diode (LED) technology, from a negligible market share to LEDs becoming the dominant lighting products within five years, despite the country's otherwise limited visibility in the global solid-state lighting industry. Full Article
ar Harvard Business School Professor Rebecca Henderson Outlines Ways Organizations are Changing in Response to the Coronavirus Pandemic and Climate Change in New Edition of "Environmental Insights" By feedproxy.google.com Published On :: Apr 8, 2020 Apr 8, 2020Rebecca Henderson, the John and Natty McArthur University Professor at Harvard University, shared her perspectives on how large organizations are changing in response to the coronavirus pandemic and climate change in the newest episode of "Environmental Insights: Discussions on Policy and Practice from the Harvard Environmental Economics Program," a podcast produced by the Harvard Environmental Economics Program. Listen to the interview here. Listen to the interview here. Full Article
ar Spotlight: Tarek Masoud By feedproxy.google.com Published On :: Mar 24, 2020 Mar 24, 2020Our Spotlight in this newsletter is on Prof. Tarek Masoud, Faculty Chair of the Middle East Initiative (MEI). In talking about MEI, Masoud says the Initiative is one of the most important ways in which HKS and Harvard engages with the contemporary Middle East. “It’s a bridge," he says. "My goal to make it into a superhighway.” Full Article
ar Can COVID-19 Be Contained in War-Torn Syria? By feedproxy.google.com Published On :: Mar 27, 2020 Mar 27, 2020The spread of the coronavirus is scary everywhere. But in Syria, which has faced war for more than nine years, humanitarian aid and health care is already stretched razor-thin. Full Article
ar Hopes and disappointments: regime change and support for democracy after the Arab Uprisings By feedproxy.google.com Published On :: Mar 27, 2020 Mar 27, 2020Analysing two waves of the Arab Barometer surveys and employing an item-response method that offers methodological improvements compared to previous studies, this article finds that support for democracy actually decreased in countries that successfully overthrew their dictators during the Uprisings. Full Article
ar The Twin Crises and the Prospects for Political Sectarianism in Lebanon By feedproxy.google.com Published On :: Apr 4, 2020 Apr 4, 2020LCPS solicited the opinion of key experts to answer one question: “Will the financial crisis, exacerbated further by COVID-19, strengthen or loosen the power of Lebanon’s governing political parties?” Full Article
ar Oil Markets Provide a Glimpse of the Post-Pandemic Future By feedproxy.google.com Published On :: Apr 7, 2020 Apr 7, 2020Henry Kissinger warns that many existing domestic and international institutions that have helped govern the past decades will not survive the Covid-19 crisis. He is surely correct. Full Article
ar Paradoxes of Professionalism: Rethinking Civil-Military Relations in the United States By feedproxy.google.com Published On :: Apr 13, 2020 Apr 13, 2020The U.S. military’s prevailing norms of military professionalism are poorly suited to meet today’s civil-military challenges. They undermine the military’s nonpartisan and apolitical ethos, weaken civilian leaders' control of military activity, and undercut the country’s strategic effectiveness in armed conflict. Full Article
ar The United States Forgot Its Strategy for Winning Cold Wars By feedproxy.google.com Published On :: May 5, 2020 May 5, 2020Stephen Walt writes that arguments against U.S. offshore balancing misunderstand history. The strategy that worked against the Soviet Union can work against China. Full Article
ar Tankyrase inhibition ameliorates lipid disorder via suppression of PGC-1α PARylation in <i>db/db</i> mice By feeds.nature.com Published On :: 2020-04-21 Full Article
ar Predictors of weight loss after bariatric surgery—a cross-disciplinary approach combining physiological, social, and psychological measures By feeds.nature.com Published On :: 2020-04-23 Full Article
ar Associations between the activity of placental nutrient-sensing pathways and neonatal and postnatal metabolic health: the ECHO Healthy Start cohort By feeds.nature.com Published On :: 2020-04-23 Full Article
ar Active travelling to school is not associated with increased total daily physical activity levels, or reduced obesity and cardiovascular/pulmonary health parameters in 10–12-year olds: a cross-sectional cohort study By feeds.nature.com Published On :: 2020-05-04 Full Article
ar Spotlight: Tarek Masoud By feedproxy.google.com Published On :: Mar 24, 2020 Mar 24, 2020Our Spotlight in this newsletter is on Prof. Tarek Masoud, Faculty Chair of the Middle East Initiative (MEI). In talking about MEI, Masoud says the Initiative is one of the most important ways in which HKS and Harvard engages with the contemporary Middle East. “It’s a bridge," he says. "My goal to make it into a superhighway.” Full Article
ar Can COVID-19 Be Contained in War-Torn Syria? By feedproxy.google.com Published On :: Mar 27, 2020 Mar 27, 2020The spread of the coronavirus is scary everywhere. But in Syria, which has faced war for more than nine years, humanitarian aid and health care is already stretched razor-thin. Full Article
ar Hopes and disappointments: regime change and support for democracy after the Arab Uprisings By feedproxy.google.com Published On :: Mar 27, 2020 Mar 27, 2020Analysing two waves of the Arab Barometer surveys and employing an item-response method that offers methodological improvements compared to previous studies, this article finds that support for democracy actually decreased in countries that successfully overthrew their dictators during the Uprisings. Full Article
ar The Twin Crises and the Prospects for Political Sectarianism in Lebanon By feedproxy.google.com Published On :: Apr 4, 2020 Apr 4, 2020LCPS solicited the opinion of key experts to answer one question: “Will the financial crisis, exacerbated further by COVID-19, strengthen or loosen the power of Lebanon’s governing political parties?” Full Article
ar Oil Markets Provide a Glimpse of the Post-Pandemic Future By feedproxy.google.com Published On :: Apr 7, 2020 Apr 7, 2020Henry Kissinger warns that many existing domestic and international institutions that have helped govern the past decades will not survive the Covid-19 crisis. He is surely correct. Full Article