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Transcriptional and epigenetic basis of Treg cell development and function: its genetic anomalies or variations in autoimmune diseases




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Molecular architecture of the luminal ring of the <i>Xenopus laevis</i> nuclear pore complex




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Structure of the cytoplasmic ring of the <i>Xenopus laevis</i> nuclear pore complex by cryo-electron microscopy single particle analysis




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Cell Research




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Why Matter Matters: How Technology Characteristics Shape the Strategic Framing of Technologies

The authors investigate how the executives of the two largest research institutes for photovoltaic technologies — the National Renewable Energy Laboratory (NREL) in Golden, USA and the Fraunhofer Institute for Solar Energy Systems (Fraunhofer ISE) in Freiburg, Germany — have made use of public framing to secure funding and shape the technological development of solar photovoltaic (PV) technologies. The article shows that the executives used four framing dimensions (potential, prospect, performance, and progress) and three framing tactics (conclusion, conditioning, and concession), and that the choice of dimensions and tactics is tightly coupled to the characteristics of the specific technologies pursued by the research institutes.




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Why the U.S. Withdrawal from the Paris Climate Accord is a Mistake

The authors explain why the Trump administration's reiteration of its intent to finalize U.S. withdrawal from the Paris Agreement is a tragic mistake that will weaken us as a nation.




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How Clean is the U.S. Steel Industry? An International Benchmarking of Energy and CO2 Intensities

In this report, the authors conduct a benchmarking analysis for energy and CO2 emissions intensity of the steel industry among the largest steel-producing countries.




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Study Group on Energy Innovation and the Transition to a Low-Carbon Economy: Advising Fortune 500 Companies

This study group will explore the role of the private sector in evolving energy systems, and how corporations might change in a climate constrained world. 




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The Value of Carbon Capture, Utilization, and Sequestration

Growing concern around climate change has ignited recent interest in carbon capture, utilization, and storage (CCUS) technologies and generated a series of studies on its global market potential.




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Geopolitical and Market Implications of Renewable Hydrogen: New Dependencies in a Low-Carbon Energy World

To accelerate the global transition to a low-carbon economy, all energy systems and sectors must be actively decarbonized. While hydrogen has been a staple in the energy and chemical industries for decades, renewable hydrogen is drawing increased attention today as a versatile and sustainable energy carrier with the potential to play an important piece in the carbon-free energy puzzle. Countries around the world are piloting new projects and policies, yet adopting hydrogen at scale will require innovating along the value chains; scaling technologies while significantly reducing costs; deploying enabling infrastructure; and defining appropriate national and international policies and market structures.

What are the general principles of how renewable hydrogen may reshape the structure of global energy markets? What are the likely geopolitical consequences such changes would cause? A deeper understanding of these nascent dynamics will allow policy makers and corporate investors to better navigate the challenges and maximize the opportunities that decarbonization will bring, without falling into the inefficient behaviors of the past.




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Illuminating Homes with LEDs in India: Rapid Market Creation Towards Low-carbon Technology Transition in a Developing Country

This paper examines a recent, rapid, and ongoing transition of India's lighting market to light emitting diode (LED) technology, from a negligible market share to LEDs becoming the dominant lighting products within five years, despite the country's otherwise limited visibility in the global solid-state lighting industry.




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Harvard Business School Professor Rebecca Henderson Outlines Ways Organizations are Changing in Response to the Coronavirus Pandemic and Climate Change in New Edition of "Environmental Insights"

Rebecca Henderson, the John and Natty McArthur University Professor at Harvard University, shared her perspectives on how large organizations are changing in response to the coronavirus pandemic and climate change in the newest episode of "Environmental Insights: Discussions on Policy and Practice from the Harvard Environmental Economics Program," a podcast produced by the Harvard Environmental Economics Program. Listen to the interview here. Listen to the interview here.




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Using physiologically-based pharmacokinetic modeling to assess the efficacy of glove materials in reducing internal doses and potential hazards of N-methylpyrrolidone during paint stripping




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Modeling and comparing central and room air conditioning ownership and cold-season in-home thermal comfort using the American Housing Survey




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Comparisons of simple and complex methods for quantifying exposure to individual point source air pollution emissions




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Correction: A characterization of personal care product use among undergraduate female college students in South Carolina, USA




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Can respirator face masks in a developing country reduce exposure to ambient particulate matter?




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Association between maternal exposure to particulate matter (PM<sub>2.5</sub>) and adverse pregnancy outcomes in Lima, Peru




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Solid fuel use and early child development disparities in Ghana: analyses by gender and urbanicity




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Getting Smart on Pandemics: Intelligence in the Wake of COVID-19

This episode of Horns of a Dilemma touches on whether the failure to properly anticipate and warn about the novel coronavirus constitutes an intelligence failure, what changes might be required in the intelligence community in the wake of the pandemic, and what type of investigation or inquiry might be appropriate in order to learn lessons and incorporate changes for both the intelligence community and the whole of government moving forward.




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This Virus Is Tough, but History Provides Perspective: The 1968 Pandemic and the Vietnam War

Nathaniel L. Moir recounts the events of 1968: The war in Vietnam and extensive civil unrest in the United States — and yet another big problem that made life harder. In 1968, the H3N2 pandemic killed more individuals in the United States than the combined total number of American fatalities during both the Vietnam and Korean Wars.




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Poll: What the American Public Likes and Hates about Trump's Nuclear Policies

The authors conducted a study which highlights how the U.S. public as a whole and various demographic groups view President Donald Trump's positions on nuclear weapons.




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The Arctic is Transforming… Can We?

Joel Clement describes how the Arctic is transforming into a warmer, wetter, and less predictable climate state, what the consequences are for the Arctic's indigenous inhabitants, and what measures can be taken to build resilience.




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UK plans 14-day compulsory quarantine for all airport arrivals

The UK is planning to bring in compulsory 14-day quarantine for all travellers arriving in the country from any part of the world, except the Republic of Ireland, as part of measures to track the spread of coronavirus.




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Rising Covid-19 cases, differences with bosses, sink Parveen Pardeshi

As Mumbai continued to lead the charts in Covid-19 cases and resultant deaths, the city’s civic chief was on Friday summarily shunted out and replaced by a junior with no experience of heading any of the state’s top five municipal corporations.




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Narendra Modi writes to Russian President; tweets greetings on occasion of 75th Victory Day anniversary

In a letter to Putin Modi pledged India’s support to Russia on the occasion and hailed Russian soldiers who laid down their lives during WW II to defeat Fascism and Nazism.




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JD(U) trashes Delhi govt's claim of bearing migrant labourers train fare

The ruling JD(U) on Saturday slammed AAP for claiming that it bore the cost of ferrying migrant workers from Delhi to their home in Bihar, saying the party was speaking "half-truth" as the Arvind Kejriwal government has sought reimbursement of the payment.




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Testing capacity for COVID-19 scaled up to 95,000 per day: Harsh Vardhan

During the high-level meeting with Arunachal Pradesh, Assam, Manipur, Meghalaya, Mizoram, Nagaland, Tripura and Sikkim, Vardhan appreciated the dedication of all the states in combating COVID-19.




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1.5 lakh migrant workers want to return to Haryana, 8 lakh want to leave: Home Minister

While nearly eight lakh migrant workers stranded in Haryana have registered themselves on a government portal to return to their native states, over 1.5 lakh of them have applied on the same portal from different states to return back to work, state Home Minister Anil Vij said.




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Arrange transportation of 9.5k migrant workers to home states, will pay their fare: Delhi Congress to CM Arvind Kejriwal

Delhi Congress wrote to the chief minister and the Delhi government's chief secretary as well, expressing its readiness to pay for the train fares of the migrants, said the Delhi Congress president. Delhi government in last few days arranged train travel of 1,200 migrant workers from Bihar and over 1,000 from MP, who were sheltered at government facilities.




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The Value of Carbon Capture, Utilization, and Sequestration

Growing concern around climate change has ignited recent interest in carbon capture, utilization, and storage (CCUS) technologies and generated a series of studies on its global market potential.




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Illuminating Homes with LEDs in India: Rapid Market Creation Towards Low-carbon Technology Transition in a Developing Country

This paper examines a recent, rapid, and ongoing transition of India's lighting market to light emitting diode (LED) technology, from a negligible market share to LEDs becoming the dominant lighting products within five years, despite the country's otherwise limited visibility in the global solid-state lighting industry.




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How Digital Service Teams are Responding to Covid-19

David Eaves writes that the most significant lesson coming out of the COVID-19 crisis  is the importance of having a digital strategy and a technological infrastructure in place at both the national and local levels.




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China and America Are Failing the Pandemic Test

All national leaders must put their countr's interests first, but the important question is how broadly or narrowly they define those interests. Both China and the US are responding to COVID-19 with an inclination toward short-term, zero-sum approaches, and too little attention to international institutions and cooperation.




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Spies Are Fighting a Shadow War Against the Coronavirus

Calder Walton describes four ways how intelligence services are certain to contribute to defeating COVID-19 and why pandemic intelligence will become a central part of future U.S. national security.




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Getting Smart on Pandemics: Intelligence in the Wake of COVID-19

This episode of Horns of a Dilemma touches on whether the failure to properly anticipate and warn about the novel coronavirus constitutes an intelligence failure, what changes might be required in the intelligence community in the wake of the pandemic, and what type of investigation or inquiry might be appropriate in order to learn lessons and incorporate changes for both the intelligence community and the whole of government moving forward.




ar

This Virus Is Tough, but History Provides Perspective: The 1968 Pandemic and the Vietnam War

Nathaniel L. Moir recounts the events of 1968: The war in Vietnam and extensive civil unrest in the United States — and yet another big problem that made life harder. In 1968, the H3N2 pandemic killed more individuals in the United States than the combined total number of American fatalities during both the Vietnam and Korean Wars.




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Poll: What the American Public Likes and Hates about Trump's Nuclear Policies

The authors conducted a study which highlights how the U.S. public as a whole and various demographic groups view President Donald Trump's positions on nuclear weapons.




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Romney's Reckless China Rhetoric Risks New Cold War

Rachel Esplin Odell argues for a wiser and more conservative strategy that resists the temptation to exaggerate the challenge posed by China.




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The United States Forgot Its Strategy for Winning Cold Wars

Stephen Walt writes that arguments against U.S. offshore balancing misunderstand history. The strategy that worked against the Soviet Union can work against China.




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Maxwell Taylor's Cold War: From Berlin to Vietnam

Nathaniel Moir reviews Maxwell Taylor's Cold War: From Berlin to Vietnam by Ingo Trauschweizer.




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Breaking the Ice: How France and the UK Could Reshape a Credible European Defense and Renew the Transatlantic Partnership

History is replete with irony, but rarely more poignantly than in the summer of 2016 when, on 23 June, the UK voted to leave the European Union and the next day, 24 June, the EU published its Global Strategy document asserting its ambition of “strategic autonomy.” Whither Franco-British defense cooperation in such chaotic circumstances? This paper attempts to provide the outline of an answer to that question.




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We Must Prepare for the Next Pandemic

Bruce Schneier explains why accurate information will be just as important as effective treatments when the next pandemic strikes.




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Capital Choices: Sectoral Politics and the Variation of Sovereign Wealth

Capital Choices analyzes the creation of different SWFs from a comparative political economy perspective, arguing that different state-society structures at the sectoral level are the drivers for SWF variation. Juergen Braunstein focuses on the early formation period of SWFs, a critical but little understood area given the high levels of political sensitivity and lack of transparency that surround SWF creation. Braunstein’s novel analytical framework provides practical lessons for the business and finance organizations and policymakers of countries that have created, or are planning to create, SWFs.




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Armed Rebel Groups Lobby in D.C., Just Like Governments. How Does That Influence U.S. Policy?

Armed rebel groups push for funding and recognition, and often get it.




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Oil Markets Provide a Glimpse of the Post-Pandemic Future

Henry Kissinger warns that many existing domestic and international institutions that have helped govern the past decades will not survive the Covid-19 crisis. He is surely correct.




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Extinction Watch: This shark doesn’t need saltwater to survive

Unlike other members of this family, the eyes of the Ganges shark are tilted dorsally, instead of laterally or ventrally, indicating that it may swim along the river bed scanning the waters above for prey. Its sharp and slender teeth suggest that it is primarily a fi sh-eater. It is often confused with the bull shark, which is known to attack humans




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Blue skies, reduced emissions only temporary, won't benefit environment in long run: Experts

Environmentalists feel that carbon emissions may have reduced drastically but are likely to go back to the pre-corona levels in a few weeks' time, once the virus threat mitigates.




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Extinction Watch: Rarely at home in the prairies

The plant has been listed as a threatened species in the United States since 1989, and in 2008 it was listed as an endangered species by the IUCN.




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Extinction Watch: This Lemur is marked for death

The Aye-aye is endangered and on the IUCN red list due to hunting and habitat destruction caused largely by humans setting fi res, illegal logging, making charcoal, as well as agriculture and livestock expansion.