Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM00061G, Paper

Hang Ren, Peng Wang, Hanwen Huang, Junshen Huang, Yuheng Lu, Yanfeng Wu, Zhongyu Xie, Youchen Tang, Zhaopeng Cai, Huiyong Shen
Modified Ti with a porous N-halaminated spermidine-containing polymeric coating is constructed, and it has both excellent antibacterial and osteogenic abilities to enhance osseointegration, making it potentially applicable in orthopedics.
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Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM00155A, Review Article

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Yungang Hu, Lu Yu, Qiang Dai, Xiaohua Hu, Yuming Shen
Due to their distinctive physical and chemical properties as well as their biological functionalities, multifunctional antibacterial hydrogels possess significant advantages in the treatment of chronic wounds.
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Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM00003J, Paper

Jing Liu, Jie Zhang, Yongteng Zhang, Wei Wei, Meixiao Zhan, Zhiren Zhang, Bing Liu, Xianglong Hu, Weiling He
Facile conjugation of chlorambucil with IR775 chloride can afford IR775-Cbl with mitochondria-targeting potency for tumor cells, exhibiting distinct “1 + 1 > 2” tumor inhibition.
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Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM00174E, Paper

Lingling Wang, Yuting Li, Xi Liu, Liyun Xing, Ruinan Wu, Yuan Huang
MNPs escaping from early endosomes and late endosomes are prone to entering the ER/GA for efficient basolateral exocytosis. However, MNPs escaping from lysosomes are detained within cells by autophagosomes.
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Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM00057A, Review Article

Zirui Dong, Kaming Xue, Anushikha Verma, Jian Shi, Zhihao Wei, Xiaotian Xia, Keshan Wang, Xiaoping Zhang
This review discussed photothermal therapy from basic information to its circumstances and potential in protate cancer treatment.
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Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM00159A, Paper

Shulei Zhang, Bo Zheng, Yiqi Wei, Yuhao Liu, Lan Yang, Yujiao Qiu, Jing Su, Mingfeng Qiu
Breast cancer, a pervasive malignancy affecting women, demands a diverse treatment approach including chemotherapy, radiotherapy, and surgical interventions.
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Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM00024B, Minireview

Pramit Kumar Ghosh, Maddila Jagapathi Rao, Chandra Lekha Putta, Sandipan Ray, Aravind Kumar Rengan
The use of nanoparticles for identifying and suppressing telomerase presents promising opportunities for anticancer strategies, particularly in relation to circadian regulation.
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Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D3BM01900D, Paper

Veronika Sarnatskaya, Yuliia Shlapa, Denis Kolesnik, Olexandra Lykhova, Dmytro Klymchuk, Serhii Solopan, Svitlana Lyubchyk, Iuliia Golovynska, Junle Qu, Yurii Stepanov, Anatolii Belous
Nano-dispersed cerium dioxide is promising for use in medicine due to its unique physicochemical properties, low toxicity, the safety of in vivo usage, active participation in different redox processes occurring in living cells, and its regenerative potential.
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Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM90027H, Correction

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Safieh Boroumand, Faraz Sigaroodi, Seyed Mohsen Ahmadi Tafti, Keyvan Khoshmaram, Masoud Soleimani, Mohammad-Mehdi Khani
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Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM90029D, Correction

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Ee Taek Hwang, Yeahwa Yoon, Ka Ram Kim, Chan Hee Lee, Kyung Chan Jeon, Ji Ho Min, Jae Won Lee, Jangyong Kim
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Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D3BM01055D, Review Article

Ziba Zakeri, Morteza Heiderzadeh, Azra Kocaarslan, Ecem Metin, Seyed Nasir Hosseini Karimi, Sepideh Saghati, Atay Vural, Göktuğ Akyoldaş, Kemal Baysal, Yusuf Yağcı, Yasemin Gürsoy-Özdemir, Savaş Taşoğlu, Reza Rahbarghazi, Emel Sokullu
The targeted delivery of pharmacologically active molecules, metabolites, and growth factors to the brain parenchyma has become one of the major challenges following the onset of neurodegeneration and pathological conditions.
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Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM90028F, Correction

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Keqin Ji, Mingrui Fan, Dong Huang, Lingna Sun, Bingqin Li, Ruoting Xu, Jiajing Zhang, Xuan Shao, Yanzuo Chen
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Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM00357H, Paper

Bin Zhang, Rui Yang, Hongwei Yu, Yamin Peng, Haoyu Huang, Meera Moydeen Abdul Hameed, Han Wang, Guixiang Zhang, Mohamed EL-Newehy, Mingwu Shen, Xiangyang Shi, Shaojun Peng
Macrophage membrane-camouflaged nanoclusters of ultrasmall iron oxide nanoparticles can be developed to cross the blood–brain barrier for magnetic resonance imaging and chemo/chemodynamic therapy.
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Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM00158C, Paper

Yiduo Chen, Yirong Guo, Xinyi Li, Yanchen Chen, Jiarong Wang, Honglin Qian, Jing Wang, Youxiang Wang, Xinyang Hu, Jian'an Wang, Jian Ji
Three surface-initiated hydrogel coatings (pMPC, pAMPS, pHEMA) are constructed on polymeric heart valves. The zwitterionic pMPC coating displays optimal performances, including durable anti-coagulation, anti-inflammation, and anti-calcification.
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Biomater. Sci., 2024, 12,1950-1964
DOI: 10.1039/D3BM01733H, Review Article

Mingjun Xie, Ji Wang, Sufan Wu, Sheng Yan, Yong He
This review introduces different methods used to generate microgels and the microgel-based bioink for bioprinting. Besides, the further tendency of microgel development in future is predicted.
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Biomater. Sci., 2024, 12,2041-2056
DOI: 10.1039/D3BM01674A, Paper

David A. McBride, James S. Wang, Wade T. Johnson, Nunzio Bottini, Nisarg J. Shah
The study develops a computational framework to model factors that lead to the evolution of autoreactive T cells in inflammatory arthritis. The results provide a tool for planning immunomodulatory strategies focused on new disease-modifying agents.
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Biomater. Sci., 2024, 12,2086-2095
DOI: 10.1039/D3BM01575K, Paper

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Pinghui Li, Zhidie Huang, Xiaoyan Duan, Tao Wang, Shaowen Yang, Dawei Jiang, Jianbo Li
We constructed ⁶⁸Ga-BDF and employed PET imaging to establish its pharmacokinetic model. BDF was eliminated from the body via the urinary system. We observed distinct imaging indicators in UUO and AKI mouse models. Furthermore, we observed the therapeutic effect of BDF on AKI.
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Biomater. Sci., 2024, 12,2121-2135
DOI: 10.1039/D3BM01901B, Paper

Ruideng Wang, Xi He, Zhengyang Chen, Shilong Su, Jinwu Bai, Haifeng Liu, Fang Zhou
A photo-crosslinked nanocomposite hydrogel was prepared by incorporating an osteo-inductive inorganic nanoparticle for endogenous bone regeneration.
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Biomater. Sci., 2024, 12,1981-2006
DOI: 10.1039/D3BM01841E, Review Article

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Ali Zareein, Mina Mahmoudi, Shruti Sunil Jadhav, Joel Wilmore, Yaoying Wu
Biomaterials enhance B cell immunity by modulating the delivery approach, crosslinking B cell receptors, and promoting T cell help, while inhibitory co-receptor engagement via biomaterial design suppresses B cell function.
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Biomater. Sci., 2024, 12,2096-2107
DOI: 10.1039/D4BM00125G, Paper

Yimeng Zhao, Xuefei Lv, Yu Chen, Chen Zhang, Di Zhou, Yulin Deng
Neuroinflammatory response on a novel combinatorial cell–cell interaction chip.
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Biomater. Sci., 2024, 12,2019-2032
DOI: 10.1039/D3BM02070C, Review Article

Zheng Wang, Zilong Chen, Zhenhao Zhang, Hongzhen Wang, Haichang Zhang
Organic fluorescent materials (OFMs) play a crucial role in the development of biosensors, enabling the extraction of biochemical information within cells and organisms, extending to the human body.
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Biomater. Sci., 2024, 12,1965-1980
DOI: 10.1039/D3BM01952G, Review Article

Fuping Zhang, Shuyu Wang, Shuo Yang, Feihe Ma, Hui Gao
Recent progress in nanomaterials for bacteria-related tumor therapy in terms of chemotherapy, immunotherapy and synergistic therapy is summarized in this review in order to provide some insights into this emerging and rapidly growing research area.
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Biomater. Sci., 2024, 12,1943-1949
DOI: 10.1039/D3BM02008H, Minireview

Yang Song
Biological liquid–liquid phase separation (LLPS) provides novel insights for the assembly of biomaterials with tailored structure and intrinsic functionality.
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Biomater. Sci., 2024, 12,2007-2018
DOI: 10.1039/D3BM02003G, Review Article

Mark-Jefferson Buer Boyetey, Yonghyun Choi, Hee-Young Lee, Jonghoon Choi
Drugs for Alzheimer's disease (AD) fail to exhibit efficacy in clinical trials for a number of reasons, a major one being blood–brain barrier (BBB) permeability.
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Biomater. Sci., 2024, 12,2067-2085
DOI: 10.1039/D3BM01466E, Paper

Akansha Dixit, Aman Mahajan, Rakshita Saxena, Saptomee Chakraborty, Dhirendra S. Katti
In this study, we combined the β-sheet mediated self-stiffening ability of silk with growth factor presenting ability of sulphated carboxymethyl cellulose in an injectable interpenetrating network hydrogel for repair of articular cartilage defects.
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Biomater. Sci., 2024, 12,2108-2120
DOI: 10.1039/D3BM02107F, Paper

Oscar Ceballos-Sanchez, Diego E. Navarro-López, Jorge L. Mejía-Méndez, Gildardo Sanchez-Ante, Vicente Rodríguez-González, Angélica Lizeth Sánchez-López, Araceli Sanchez-Martinez, Sergio M. Duron-Torres, Karla Juarez-Moreno, Naveen Tiwari, Edgar R. López-Mena
The antioxidant capabilities of nanoparticles are contingent upon various factors, including their shape, size, and chemical composition.
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Biomater. Sci., 2024, 12,2136-2148
DOI: 10.1039/D3BM01912H, Paper

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Edina Sehic, Lucía de Miguel Gómez, Hardis Rabe, Emy Thorén, Ingigerdur Gudmundsdottir, Mihai Oltean, Randa Akouri, Mats Brännström, Mats Hellström
Innovative bioengineering strategies utilizing extracellular matrix (ECM) based scaffolds derived from decellularized tissue offer new prospects for restoring damaged uterine tissue.
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Biomater. Sci., 2024, 12,2033-2040
DOI: 10.1039/D4BM00004H, Review Article

Yifan Zheng, Yudi Du, Ling Chen, Wei Mao, Yuan Pu, Steven Wang, Dan Wang
Shape memory polymers (SMPs), which initiate shape transformation in response to environmental stimuli, have attracted significant attention in both academic research and technological innovation.
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Biomater. Sci., 2024, 12,2057-2066
DOI: 10.1039/D3BM02071A, Paper

Song Lin, Houjin Jing, Xiaojiao Du, Xianzhu Yang, Jun Wang
A siRNA delivery system was developed using clinically approved mPEG-b-PLGA, cationic lipid and ionizable lipid for siRNA delivery and cancer immunotherapy.
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Biomater. Sci., 2024, 12,2149-2164
DOI: 10.1039/D3BM01911J, Paper

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Sofia F. Melo, Alicia Nondonfaz, Abdelhafid Aqil, Anna Pierrard, Alexia Hulin, Céline Delierneux, Bartosz Ditkowski, Maxime Gustin, Maxime Legrand, Bibian M. E. Tullemans, Sanne L. N. Brouns, Alain Nchimi, Raoul Carrus, Astrid Dejosé, Johan W. M. Heemskerk, Marijke J. E. Kuijpers, Jan Ritter, Ulrich Steinseifer, Johanna C. Clauser, Christine Jérôme, Patrizio Lancellotti, Cécile Oury
Non-isocyanate polyurethanes (NIPUs) were developed and tested in vitro. Prosthetic heart valves made of NIPU were designed and manufactured. NIPUs showed low thrombogenicity and the produced valves performed well in terms of hydrodynamics.
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Biomater. Sci., 2024, 12,2167-2167
DOI: 10.1039/D4BM90023E, Retraction

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Tao Li, Hongtao He, Zezheng Yang, Junjie Wang, Yuxin Zhang, Guangxu He, Jun Huang, Deye Song, Jiangdong Ni, Xiaojun Zhou, Junfeng Zhu, Muliang Ding
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Biomater. Sci., 2024, 12,2165-2166
DOI: 10.1039/D4BM90022G, Correction

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Yinjie Wang, Zhenqi Jiang, Bo Yuan, Yuchen Tian, Lingchao Xiang, Yanying Li, Yong Yang, Juan Li, Aiguo Wu
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Biomater. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D3BM02017G, Review Article

Zhiwei Xu, Bingbing Wang, Ruoyu Huang, Mengyao Guo, Di Han, Lan Yin, Xiaoyun Zhang, Yong Huang, Xiaoming Li
Repair of bone defects exceeding critical size has been always a big challenge in clinic. Tissue engineering has exhibited great potentials to effectively repair the defects with less adverse effect...
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Biomater. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4BM00234B, Paper

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Gaëlle Savin, Sylvain Caillol, Audrey Bethry, Eric Rondet, Michel Assor, Ghislain David, Benjamin Nottelet
Focusing on the regeneration of damaged knee meniscus, we propose a hybrid scaffold made of a poly(ester-urethane) (PEU) and collagen that combines suitable mechanical properties and degradability with enhanced biological...
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Biomater. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4BM00048J, Review Article

Hewan Dawit, Yuewu Zhao, Jine Wang, Renjun Pei
The brain-computer interface (BCI) allows the human or animal brain to direct interact with the external environment through the neural interfaces, thus playing the role of monitoring, protecting, improving/restoring, enhancing,...
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Biomater. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4BM00319E, Review Article

Minzi Ju, Lu Yang, Guowei Wang, Feng Zong, Yu Shen, Shuangshuang Wu, Xuna Tang, Decai Yu
Photodynamic therapy (PDT) is a minimally invasive therapeutic modality employed for the treatment of various types of cancers, localized infections, and other diseases. Upon illumination, the photo-excited photosensitizer generates singlet...
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Biomater. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4BM00164H, Paper

Wenmo Zhang, Runze Zhang, Rong Yang, Yage Sun, Qian Zhang, Xuequan Feng, Chunyan Cui, Wenguang Liu
Intestine damage is an acute abdominal disease that usually requires emergency sealing. However, traditional surgical suture not only causes secondary damage to the injured tissue, but also results in adhesion...
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Biomater. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D3BM02114A, Review Article

Di Huang, Xiaoyu Wang, Wentao Wang, Jiachen Li, Xiaomei Zhang, Bing Xia
Cells are the fundamental units of life. The cell membrane primarily composed of two layers of phospholipids (a bilayer) structurally defines the boundary of a cell, which can protect its...
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Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM00412D, Paper

Hao Fu, Yongxin Zhang, Cheng Wang, Zhencheng Sun, Shuyi Lv, Minghui Xiao, Kaiyu Wu, Linqi Shi, Chunlei Zhu
A universal strategy is developed to remarkably enhance the photothermal conversion efficiency of photothermal materials. This advancement enables effective treatment of drug-resistant bacterial infections through safe photothermal therapy.
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Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D3BM02074F, Paper

Yanzhi Dong, Jiaojiao Wang, Ting Zhou, Jinbing Pan, Xu Wang, Shao-Kai Sun
We developed ultrasmall catechol-PEG-anchored ferrite nanoparticles for highly sensitive MRA. The probe enables the diagnosis of carotid artery stenosis and subsequent evaluation of reperfusion through a single injection.
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Biomater. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D3BM01687K, Review Article

Xuan Wang, Fushuang Liu, Tianyi Wang, Yikai He, Yongwen Guo
Epidemiological studies reveal that symptoms of TMD occur in 60-70% of adults. The inflammatory damage caused by TMD can easily lead to defects in the articular disc, condylar cartilage, subchondral...
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Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM90033B, Correction

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Ya Liu, Yajun Xu, Ying Wang, Jianlin Lv, Kun Wang, Zhaohui Tang
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Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM00289J, Paper

Rui Ding, Pandi Peng, Jingjing Huo, Kun Wang, Pengxiang Liu, Hanxue Wu, Likun Yan, Peng Li
This work demonstrates that CT coatings would be a promising material against implant-related infection in a pH-responsive manner including but not limited to the field of hernioplasty.
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Biomater. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4BM00313F, Review Article

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Hana Cho, Kang Moo Huh, Hyun Ji Cho, Bogeon Kim, Min Suk Shim, Yong-Yeon Cho, Joo Young Lee, Hye Suk Lee, Young Jik Kwon, Han Chang Kang
Various strategies in the microscale/nanoscale have been developed to improve oral absorption of therapeutics. Among them, gastrointestinal (GI)-transporter/receptor-mediated nanosized drug delivery systems (NDDSs) have drawn attention due to their many...
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Biomater. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4BM00214H, Review Article

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Xin-Gui Li, Junjian Li, Jinfeng Chen, Liangmei Rao, Libin Zheng, Fei Yu, Yijing Tang, Jie Zheng, Jie Ma
Covalent organic frameworks (COFs) constitute a class of highly functional porous materials characterized by ordered structures, high crystallinity, and a substantial specific surface area, primarily composed of light atoms such...
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Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM00182F, Paper

Renquan Xing, Rui Gao, Yini Huangfu, Yufeng Zhang, Shuangyang Li, Chuangnian Zhang, Pingsheng Huang, Weiwei Wang, Anjie Dong, Zujian Feng
A promising bioactive microgel-coated electrospun membrane with cell-instructive interfaces and topology for abdominal wall defect repair.
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Biomater. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D3BM02020G, Paper

Gayathri Ediriweera, Neville Butcher, Ashok Kothapalli, Jiacheng Zhao, Joanne Therese Blanchfield, Christopher N. Subasic, James Lynden Grace, Changkui Fu, Xiao Tan, John F. Quinn, David Ascher, Michael R Whittaker, Andrew Whittaker, Lisa Kaminskas
Inhalable nanomedicines are increasingly being developed to optimise the pharmaceutical treatment of respiratory diseases. Large lipid-based nanosystems at the forefront of the inhalable nanomedicines development pipeline, though, have a number...
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Biomater. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4BM00099D, Paper

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Maya Rima, Christina Villeneuve-Faure, Marvine Soumbo, Fatima El Garah, Ludovic Pilloux, Christine Roques, Kremena Makasheva
The interaction of foreign implants with its surrounding environment is significantly influenced by the adsorption of proteins on the biomaterial surfaces, playing role in the microbial adhesion. Therefore, understanding protein...
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Biomater. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4BM00107A, Paper

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Lesley Trask, Niamh A. Ward, Ruth Tarpey, Rachel Beatty, Eimear Wallace, Joanne O'Dwyer, William Ronan, Garry P. Duffy, Eimear B. Dolan
Implantable medical devices that can facilitate therapy transport to localized sites are being developed for a number of diverse applications, including the treatment of diseases such as diabetes and cancer,...
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Biomater. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4BM00039K, Paper

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Siobhan Crilly, Victor Sebastian Tapia, Carlo Bawn, Annalisa Tirella
Intracerebral haemorrhage (ICH) is a devastating neurovascular attack with limited treatment options. Alternative, pre-clinical modelling approaches are required to identify and trial therapeutic drug compounds. In this study we have...
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