The World Curling Federation announced Thursday it is proposing to the International Olympic Committee that the 2021 world curling championships will determine which countries will book their tickets to Beijing 2022.

The time was right for Lisa Weagle to join forces with Olympic champion Jennifer Jones. Jones told CBC Sports' Anastasia Bucsis that the latest addition to her five-person rink "was like the clouds parted and the sun came out."

Will he, given his obsession with the economy?

He’s not rising to the challenge of the coronavirus pandemic. He’s shriveling into nothingness.

The notion that he is bound for four more years is pure superstition.

Laurie Garrett, the prophet of this pandemic, expects years of death and “collective rage.”

Flattening the curve has been so successful and two areas around Hamilton — Brant and Haldimand-Norfolk — haven't had a new case of COVID-19 in three days, and Burlington has only had two.

The province says no one has to tell others if they get COVID-19. The same goes for businesses or landlords, should employees or tenants get sick. But should you tell?

Government restrictions designed to limit the spread of COVID-19 have virtually crippled Ontario's wine-making industry, as retail and wholesale revenues dry up but the costs of producing wine remains constant.

Front-line nurses from the West 5th campus use a special van to meet patients with mental health problems — primarily those living with schizophrenia— and treat them by doing their blood work.

Fears that COVID-19 would spread at the Hamilton-Wentworth Detention Centre appear not to have materialized — at least not yet.

Two additional men have been charged with first-degree murder in the death of a 17-year-old Brampton boy shot and killed on New Year's Eve.

Curbside pickups offer a bit of hope after months of being shuttered by COVID-19, but while retailers are happy to start getting back to business some are raising questions of fairness and access to opportunity.

Flurries or rain showers are in the forecast for Hamilton on Friday, Environment Canada says.

A search warrant executed by Hamilton police vice and drugs officers at an address in the city’s east end has resulted in the arrest of a couple and multiple charges, police said in a Friday release.

Normal life is slowly resuming as the city of Hamilton begins to relax tight measures set in place because of COVID-19. Mayor Fred Eisenberger said now it's up to the public to help the city move in the right direction by continuing to stay two metres apart from each other and be cautious.

Determining the concentration of protein samples generally is accomplished either by measuring the UV absorbance at 280 nm or by reacting the protein quantitatively with dyes and/or metal ions (Bradford, Lowry, or BCA assays). For purified proteins, UV absorbance remains the most popular method because it is fast, convenient, and reproducible; it does not consume the protein; and it requires no additional reagents, standards, or incubations. No method of protein concentration determination is perfect because each is subject to a different set of constraints such as interference of buffer components and contaminating proteins in direct UV determination (A₂₈₀) or reactivity of individual proteins and buffer components with the detecting reagents in colorimetric assays. In cases in which protein concentration is critical (e.g., determination of catalytic rate constants for an enzyme), it may be advisable to compare the results of several assays.

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One of the main mechanisms of azole resistance of Aspergillus fumigatus is thought to be a reduction in the drug’s affinity for the target molecule, Cyp51A, due to its amino acid mutation(s). It is known that the azole resistance pattern is closely related to the mutation site(s) of the molecule. In this study, we tried to develop a simple and rapid detection method for cyp51A mutations using the endonuclease Surveyor nuclease. The Surveyor nuclease assay was verified using several azole-resistant strains of A. fumigatus that possess point mutations in Cyp51A. For validation of the Surveyor nuclease assay, blind tests were conducted using 48 strains of A. fumigatus (17 azole-resistant and 31 azole-susceptible strains). The Surveyor nuclease assay could rapidly detect cyp51A mutations with one primer set. Also, all the tested strains harboring different cyp51A single point mutations could be clearly distinguished from the wild type. The Surveyor nuclease assay is a simple method that can detect cyp51A mutations rapidly.

This report outlines the progress made by banks in implementing the Basel Committee's Principles for effective risk data aggregation and risk reporting ("the Principles" or "BCBS 239")1 based on supervisors' assessments conducted in 2019.

FSI Briefs No 5, April 2020. In response to the Covid-19 pandemic, governments have launched guarantee programmes to support bank lending to companies, especially small and medium-sized enterprises. This is essential to avoid a sharp contraction in bank credit that would exacerbate the pandemic's adverse impact. The design of such programmes needs to strike a difficult balance between responding promptly to the pandemic and maintaining a sufficient level of prudence. Key features of a sample of programmes (eg target beneficiaries, coverage of the guarantee, loan terms, length of the programme) reflect this tension. Incentives were created for the banks to join these programmes by exploiting flexibility in existing prudential requirements, while central banks have often provided liquidity support. Programmes are, however, subject to operational challenges and, ultimately, fiscal capacity limits.

Introductory statement by Ms Christine Lagarde, President of the European Central Bank, and Mr Luis de Guindos, Vice-President of the European Central Bank, Frankfurt am Main, 30 April 2020.

Advanced preliminary release for Q4 2019 quarterly data on total credit to the non-financial sectors; comprising private non-financial sector and general government for 44 economies and regional aggregates have been updated. Data are available for the following borrowing subsectors: general government, private non-financial sector (series on credit from domestic banks as lending sector are also available), non-financial corporations and households. Data are presented in three versions: in billions of local currency and US dollars, and as a percentage of GDP.

Advanced preliminary release for Q4 2019 quarterly data on debt service ratios (DSRs) for the private non-financial sector (PNFS) for 32 countries have been updated. DSRs for PNFS breakdown sectors, ie for households and for non-financial corporations are also available for 17 countries.

The BIS's data set on consumer prices contains long monthly and annual time series for 60 countries.

BCBS Press release "Basel Committee publishes stocktake report on climate-related financial risk initiatives'", 30 April 2020