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Global Icons : Stephen Hawking [electronic resource]




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Against the grain [electronic resource] : advances in postcolonial organization studies / Anshuman Prasad (editor)




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The art of community [electronic resource] : seven principles for belonging / Charles H. Vogl

Vogl, Charles H., author




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City of Crisis [electronic resource] : The Multiple Contestation of Southern European Cities / edited by Frank Eckardt, Javier Ruiz Sánchez




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Class and campus life [electronic resource] : managing and experiencing inequality at an elite college / Elizabeth M. Lee

Lee, Elizabeth M., 1974- author




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The econosphere [electronic resource] : what makes the economy really work, how to protect it, and maximize your opportunity for financial prosperity / Craig Thomas

Thomas, Craig, 1969-




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L'évaluation du travail à l'épreuve du réel [electronic resource] : critique des fondements de l'évaluation : une conférence-débat organisée par le groupe Sciences en questions, Paris, INRA, 20 mars 2003

Dejours, Christophe, author




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L'évaluation du travail à l'épreuve du réel [electronic resource] : critique des fondements de l'évaluation : une conférence-débat organisée par le groupe Sciences en questions, Paris, INRA, 20 Mars 2003

Dejours, Christophe, author




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Gender, Masculinity and Video Gaming [electronic resource] : Analysing Reddit's r/gaming Community / by Marcus Maloney, Steven Roberts, Timothy Graham

Maloney, Marcus. author




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Living with climate change [electronic resource] : how communities are surviving and thriving in a changing climate / Jane A. Bullock, George D. Haddow, Kim S. Haddow, Damon P. Coppola

Bullock, Jane A., author




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Où cache biodiversité ville se en la ? [electronic resource] : 90 clés pour comprendre la nature en ville / Philippe Clergeau, Nathalie Machon

Clergeau, Philippe, author




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Sociologie des Grandes Cultures [electronic resource] : Au Cœur du Modèle Industriel Agricole / Antoine Bernard de Raymond, Frédééric Goulet, coordinateurs




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Rural Cinema Exhibition and Audiences in a Global Context [electronic resource]




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Female criminality [electronic resource] : infanticide, moral panics and the female body / Annie Cossins

Cossins, Anne, author




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Understanding street culture : poverty, crime, youth and cool / Jonathan Ilan

Ilan, Jonathan




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Variable protein expression in marine-derived filamentous fungus Penicillium chrysogenum in response to varying copper concentrations and salinity

Metallomics, 2020, Advance Article
DOI: 10.1039/C9MT00316A, Paper
Nikita Lotlikar, Samir Damare, Ram Murti Meena, Saranya Jayachandran
Copper is one of the essential trace dietary minerals for all living organisms, but is potentially toxic at higher concentrations, mainly due to the redox reactions in its transition state.
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Characterization of the Fe metalloproteome of a ubiquitous marine heterotroph, Pseudoalteromonas (BB2-AT2): multiple bacterioferritin copies enable significant Fe storage

Metallomics, 2020, Advance Article
DOI: 10.1039/D0MT00034E, Paper
Open Access
Michael G. Mazzotta, Matthew R. McIlvin, Mak A. Saito
Despite the extreme scarcity of Fe in seawater, the marine heterotroph Pseudoalteromonas has expansive Fe storage capacity and utilization strategies.
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Chromatographic detection of low-molecular-mass metal complexes in the cytosol of Saccharomyces cerevisiae

Metallomics, 2020, Advance Article
DOI: 10.1039/C9MT00312F, Paper
Open Access
Trang Q. Nguyen, Joshua E. Kim, Hayley N. Brawley, Paul A. Lindahl
Labile metal pools in the cytosol of yeast, including those of iron, copper, zinc, and manganese, can be detected and characterized using size-exclusion chromatography with online ICP-MS.
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Hydrogen sulfide increases copper-dependent neurotoxicity via intracellular copper accumulation

Metallomics, 2020, Advance Article
DOI: 10.1039/D0MT00015A, Paper
Norika Goto, Hirokazu Hara, Mao Kondo, Naomi Yasuda, Tetsuro Kamiya, Kensuke Okuda, Tetsuo Adachi
Copper (Cu) is an essential trace element and acts as a redox cofactor for many enzymes; however, excess Cu is toxic to cells.
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Proteomic analysis of the S. cerevisiae response to the anticancer ruthenium complex KP1019

Metallomics, 2020, Advance Article
DOI: 10.1039/D0MT00008F, Paper
Open Access
Laura K. Stultz, Alexandra Hunsucker, Sydney Middleton, Evan Grovenstein, Jacob O’Leary, Eliot Blatt, Mary Miller, James Mobley, Pamela K. Hanson
Proteomic analysis reveals that the anticancer ruthenium KP1019 induces proteotoxic, genotoxic, and oxidative stress responses in Saccharomyces cerevisiae.
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The first copper(II) complex with 1,10-phenanthroline and salubrinal with interesting biochemical properties

Metallomics, 2020, Advance Article
DOI: 10.1039/D0MT00006J, Paper
Sebastiano Masuri, Enzo Cadoni, Maria Grazia Cabiddu, Francesco Isaia, Maria Giovanna Demuru, Lukáš Moráň, David Buček, Petr Vaňhara, Josef Havel, Tiziana Pivetta
The novel complex Cu(phen)2(salubrinal)(ClO4)2 shows high free radical scavenging activity and good cytotoxic activity and induces cell death through ER-stress.
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Gold(III) bis(dithiolene) complexes: from molecular conductors to prospective anticancer, antimicrobial and antiplasmodial agents

Metallomics, 2020, Accepted Manuscript
DOI: 10.1039/D0MT00064G, Paper
Diana Fontinha, Silvia Andreia Sousa, Tânia S. Morais, Miguel Prudêncio, Jorge Leitão, Yann Le Gal, Dominique Lorcy, Rafaela Silva, Mariana Velho, Dulce Belo, Manuel Almeida, Joana Guerreiro, Teresa Pinheiro, Fernanda M. Marques
The anticancer, antimicrobial and antiplasmodial activities of six gold(III) bis(dithiolene) complexes were studied. Complexes (1-6) showed relevant anticancer properties against A2780/A2780cisR ovarian cancer cells (IC50 values of 0.08-2 µM), also...
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Enantiomeric Copper Based Anticancer Agents Promoting Sequence-Selective Cleavage of G-Quadruplex Telomeric DNA and non-random cleavage of plasmid DNA

Metallomics, 2020, Accepted Manuscript
DOI: 10.1039/D0MT00084A, Paper
Sabiha Parveen, J. A. Cowan, Zhen Yu, Farukh Arjmand
Copper-based binuclear enantiomeric complexes 1S and 1R were synthesized as anticancer chemotherapeutic agents to target G-quadruplex rich region of DNA and thoroughly characterized by various spectroscopic and single X-ray crystal...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Chiral Ru(II) complexes act as a potential non-viral gene carrier for directional transportation to the nucleus and cytoplasm

Metallomics, 2020, 12,504-513
DOI: 10.1039/C9MT00192A, Paper
Qiong Wu, Shuang-Yan Zhang, Si-Yan Liao, Jie-Qiong Cao, Wen-Jie Zheng, Li Li, Wen-Jie Mei
A novel approach has been proposed to develop a potent gene carrier system for enantioselectivity on the self-assembly of G-quadruplex DNA promoted by chiral Ru(II) complexes, and the different assembled nanostructures of cellular uptake to the nucleus and cytoplasm.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Heterobimetallic Ru(II)/Fe(II) complexes as potent anticancer agents against breast cancer cells, inducing apoptosis through multiple targets

Metallomics, 2020, 12,547-561
DOI: 10.1039/C9MT00272C, Paper
Adriana Pereira Mundim Guedes, Francyelli Mello-Andrade, Wanessa Carvalho Pires, Maria Alice Montes de Sousa, Paula Francinete Faustino da Silva, Mariana S. de Camargo, Hendryk Gemeiner, Menegário A. Amauri, Clever Gomes Cardoso, Paulo Roberto de Melo Reis, Elisângela de Paula Silveira-Lacerda, Alzir A. Batista
Antimetastatic activity, high selectivity and cytotoxicity for human tumor cell lines make ruthenium(II) complexes attractive for the development of new chemotherapeutic agents for cancer treatment.
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Copper accumulation and the effect of chelation treatment on cerebral amyloid angiopathy compared to parenchymal amyloid plaques

Metallomics, 2020, 12,539-546
DOI: 10.1039/C9MT00306A, Paper
Xiayoue Zhu, Tiffany W. Victor, Ashwin Ambi, Joseph K. Sullivan, Joshua Hatfield, Feng Xu, Lisa M. Miller, William E. Van Nostrand
Multimodal imaging studies show that Aβ amyloid in brain vessels of Tg2576 mice (green) preferentially binds copper (red) – a pathology that can be reduced with copper chelators.
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Comparative differential cuproproteomes of Rhodobacter capsulatus reveal novel copper homeostasis related proteins

Metallomics, 2020, 12,572-591
DOI: 10.1039/C9MT00314B, Paper
Nur Selamoglu, Özlem Önder, Yavuz Öztürk, Bahia Khalfaoui-Hassani, Crysten E. Blaby-Haas, Benjamin A. Garcia, Hans-Georg Koch, Fevzi Daldal
Cuproproteome of model bacterium Rhodobacter capsulatus reveals 75 Cu-responsive proteins that are strongly influenced (2–300 fold) by Cu availability.
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Correction: Bis(ethylmaltolato)oxidovanadium(IV) inhibited the pathogenesis of Alzheimer's disease in triple transgenic model mice

Metallomics, 2020, 12,631-631
DOI: 10.1039/D0MT90008G, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Zhijun He, Shuangxue Han, Chong Wu, Lina Liu, Huazhang Zhu, Ang Liu, Qiying Lu, Jingqiang Huang, Xiubo Du, Nan Li, Qingguo Xie, Lu Wan, Jiazuan Ni, Lingling Chen, Xiaogai Yang, Qiong Liu
The content of this RSS Feed (c) The Royal Society of Chemistry




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Hierarchical binding of copperII to N-truncated Aβ4–16 peptide

Metallomics, 2020, 12,470-473
DOI: 10.1039/C9MT00299E, Communication
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Xiangyu Teng, Ewelina Stefaniak, Paul Girvan, Radosław Kotuniak, Dawid Płonka, Wojciech Bal, Liming Ying
Multiple intermediates were found in Cu(II) binding to Aβ4–16 before the formation of a tight complex.
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Ruthenium(III) complexes containing thiazole-based ligands that modulate amyloid-β aggregation

Metallomics, 2020, 12,491-503
DOI: 10.1039/D0MT00054J, Paper
Samantha E. Huffman, Gideon K. Yawson, Samuel S. Fisher, Paige J. Bothwell, David C. Platt, Marjorie A. Jones, Christopher G. Hamaker, Michael I. Webb
Alzheimer's Disease (AD) is a devastating neurodegenerative disorder where one of the commonly observed pathological hallmarks is extracellular deposits of the peptide amyloid-β (Aβ).
The content of this RSS Feed (c) The Royal Society of Chemistry




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Peptide bond cleavage in the presence of Ni-containing particles

Metallomics, 2020, Accepted Manuscript
DOI: 10.1039/D0MT00070A, Communication
Nina Ewa Wezynfeld, Tomasz Frączyk, Arkadiusz Bonna, Wojciech Bal
NiO nanoparticles and non-stoichiometric black NiO were shown to be effective sources of Ni2+ ions causing sequence-selective peptide bond hydrolysis. NiO nanoparticles were as effective in this reaction as their...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Correction: Identification and determination of selenocysteine, selenosugar, and other selenometabolites in turkey liver

Metallomics, 2020, Advance Article
DOI: 10.1039/D0MT90015J, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Katarzyna Bierla, Rachel M. Taylor, Joanna Szpunar, Ryszard Lobinski, Roger A. Sunde
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Investigation of the impact of magnesium versus titanium implants on protein composition in osteoblast by label free quantification

Metallomics, 2020, Advance Article
DOI: 10.1039/D0MT00028K, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
M. Omidi, N. Ahmad Agha, A. Müller, F. Feyerabend, H. Helmholz, R. Willumeit-Römer, H. Schlüter, B. J. C. Luthringer-Feyerabend
To our knowledge, this is the first report describing and comparing the effects of magnesium and titanium biomaterials on human osteoblast proteome.
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The study of levels from redox-active elements in cerebrospinal fluid of amyotrophic lateral sclerosis patients carrying disease-related gene mutations shows potential copper dyshomeostasis

Metallomics, 2020, Advance Article
DOI: 10.1039/D0MT00051E, Paper
Federica Violi, Nikolay Solovyev, Marco Vinceti, Jessica Mandrioli, Marianna Lucio, Bernhard Michalke
Gene-environment interaction is as a possible key factor in the development of ALS. The levels of redox species of Cu, Fe, and Mn were assessed in cerebrospinal fluid, showing a possible positive association between Cu and genetic ALS.
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A Companion to the Harlem Renaissance


 

A Companion to the Harlem Renaissance presents a comprehensive collection of original essays that address the literature and culture of the Harlem Renaissance from the end of World War I to the middle of the 1930s.



Read More...




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Arms and ammos recovered

Arms and ammos recovered




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[ASAP] In Vitro Identification of the Hamiltonian Cycle Using a Circular Structure Assisted DNA Computer

ACS Combinatorial Science
DOI: 10.1021/acscombsci.9b00150




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[ASAP] Development of Mischmetal–Fe–Co–B Permanent Magnet Alloys via High-Throughput Methods

ACS Combinatorial Science
DOI: 10.1021/acscombsci.9b00190




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[ASAP] Ce(OTf)<sub>3</sub>-Catalyzed Multicomponent Reaction of Alkynyl Carboxylic Acids, <italic toggle="yes">tert</italic>-Butyl Isocyanide, and Azides for the Assembly of Triazole–Oxazole Derivatives

ACS Combinatorial Science
DOI: 10.1021/acscombsci.0c00012




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[ASAP] Immobilized Carbodiimide Assisted Flow Combinatorial Protocol to Facilitate Amide Coupling and Lactamization

ACS Combinatorial Science
DOI: 10.1021/acscombsci.0c00001




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[ASAP] Update to Our Reader, Reviewer, and Author Communities—April 2020

ACS Combinatorial Science
DOI: 10.1021/acscombsci.0c00061




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[ASAP] Optimized Multimetal Sensitized Phosphor for Enhanced Red Up-Conversion Luminescence by Machine Learning

ACS Combinatorial Science
DOI: 10.1021/acscombsci.0c00035




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[ASAP] Experimental and Theoretical Investigation on Phase Formation and Mechanical Properties in Cr–Co–Ni Alloys Processed Using a Novel Thin-Film Quenching Technique

ACS Combinatorial Science
DOI: 10.1021/acscombsci.9b00170




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Annual Report to the Nation: Overall cancer mortality continues to decline; Special section on adults ages 20 to 49 shows higher cancer incidence and mortality for women than men

The 2019 Annual Report to the Nation on the Status of Cancer finds overall cancer death rates continue to decline and cancer incidence dropped in men and remained stable in women. A special section reports on recent cancer trends in younger adults.




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NCI study finds long-term increased risk of cancer death following common treatment for hyperthyroidism

Findings from a new NCI study of patients who received radioactive iodine (RAI) treatment for hyperthyroidism show an association between the dose of treatment and long-term risk of death from solid cancers, including breast cancer.




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Immunotherapy drug improves outcomes for some children with relapsed leukemia

For children and young adults with certain relapsed B-cell acute lymphoblastic leukemia (B-ALL), the immunotherapy drug blinatumomab is superior to standard chemotherapy, an NCI-sponsored Children’s Oncology Group trial shows.




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Testing with combined biopsy method improves prostate cancer diagnosis in NCI study

Testing for prostate cancer with a combined biopsy method led to more accurate diagnosis and prediction of the course of the disease in an NCI study. The method is poised to reduce the risk of prostate cancer overtreatment and undertreatment.




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Annual Report to the Nation: Cancer death rates continue to decline

The 2020 Annual Report to the Nation on the Status of Cancer finds overall cancer death rates continue to decline in the United States for all cancer sites combined. A companion study looked at Healthy People 2020 targets for four common cancers.




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NCI study provides genetic insights into osteosarcoma in children

A new study offers insight into genetic alterations associated with osteosarcoma, the most common bone tumor of children and adolescents, and the findings have implications for genetic testing of children with osteosarcoma and their families.




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NCI statement on clinical trials during COVID-19 pandemic

Statement from the National Cancer Institute providing information regarding treatment of cancer patients and participation in clinical trials during the COVID-19 pandemic.