ma A New 3D Scan, Created from 25,000 High-Resolution Images, Reveals the Remarkably Well-Preserved Wreck of Shackleton’s Endurance By www.openculture.com Published On :: Wed, 13 Nov 2024 10:00:16 +0000 Photos on this page courtesy of the Falklands Maritime Heritage Few who hear the story of the Endurance could avoid reflecting on the aptness of the ship’s name. A year after setting out on the Imperial Trans-Antarctic Expedition in 1914, it got stuck in a mass of drifting ice off Antarctica. There it remained for ten months, […] Full Article Film History
ma Pregnant woman dies in road accident in Salem By www.thehindu.com Published On :: Wed, 13 Nov 2024 18:46:18 +0530 Full Article Coimbatore
ma Legal battle over permanent English teacher appointments in high school continues By www.thehindu.com Published On :: Wed, 13 Nov 2024 20:27:56 +0530 Govt cites financial problems; PSC rank-holders say posts are being created for other language subjects Full Article Kerala
ma Ambulance aggregator service under consideration: Ganesh Kumar By www.thehindu.com Published On :: Wed, 13 Nov 2024 20:31:35 +0530 Aimed at enhancing emergency response across Kerala Full Article Kerala
ma Watch: Which are the smaller parties in the fray in Maharashtra? | Election Cheatsheet By www.thehindu.com Published On :: Wed, 13 Nov 2024 21:02:53 +0530 We take a look at the various political alliances in the Maharashtra ahead of the Assembly elections in the State. Full Article Videos
ma Pilgrims visiting Sabarimala to get nowcast from Nov. 15 By www.thehindu.com Published On :: Wed, 13 Nov 2024 21:18:46 +0530 Hygrometers to measure humidity and thermometers will be installed on the shrine premises soon to provide weather services to pilgrims, says IMD Director Full Article Kerala
ma Omar seeks compensation from Centre over losses due to Indus Water Treaty By www.thehindu.com Published On :: Thu, 14 Nov 2024 07:34:51 +0530 Jammu and Kashmir Chief Minister’s remarks that the IWT hinders J&K’s power capacity spark row; the focus should be the return of power projects from National Hydroelectric Power Corporation, says former Chief Minister Mehbooba Mufti Full Article India
ma BJP accuses Congress of releasing election manifesto during “silence” period in Jharkhand By www.thehindu.com Published On :: Thu, 14 Nov 2024 07:40:16 +0530 Mr. Patra claimed that the Congress wanted to give 4% reservation to the Muslim organisations and contractors in public tenders Full Article Jharkhand Assembly
ma NIFT’s craft cluster projects enriching J&K’s artisans, crafts: L-G Manoj Sinha By www.thehindu.com Published On :: Thu, 14 Nov 2024 07:46:32 +0530 He described J&K as “a repository of Indian creative traditions Full Article India
ma ED arrests four, including two Bangladeshi nationals, in human trafficking case By www.thehindu.com Published On :: Thu, 14 Nov 2024 07:52:22 +0530 Full Article India
ma Mamata calls for unity of hills and plains; focuses on development in north Bengal By www.thehindu.com Published On :: Thu, 14 Nov 2024 07:55:01 +0530 This is her first official visit to Darjeeling in two years; she did not go to the hills even during the 2024 Lok Sabha election campaigns Full Article West Bengal
ma BRSV and AISF demand thorough probe into RGUKT student’s death By www.thehindu.com Published On :: Wed, 13 Nov 2024 14:02:18 +0530 Full Article Telangana
ma Nirmal Municipality junior assistant in ACB net By www.thehindu.com Published On :: Wed, 13 Nov 2024 19:03:40 +0530 Full Article Telangana
ma Hyderabad GPO extends operating hours for mail bookings By www.thehindu.com Published On :: Wed, 13 Nov 2024 20:49:21 +0530 Full Article Telangana
ma Amaran collection in TN crosses ₹100 crore within two weeks; global collection ₹250 crore By www.thehindubusinessline.com Published On :: Wed, 13 Nov 2024 09:27:11 +0530 Global collection of Amaran in the first 11 days was ₹248 crore, which was far less than the Vijay starrer The GOAT that had a whopping collection of ₹397 crore but ahead of Rajinikanth’s Vettaiyan at ₹225 crore, according to data Full Article Variety
ma India IT spending to reach USD 160 billion in 2025 fueled by application and infrastructure software market growth: Gartner By www.newkerala.com Published On :: Wed, 13 Nov 2024 17:38:01 +0530 Full Article
ma EU, Belgium, Denmark and Germany envoys visit Adani's Khavda, Mundra businesses, Gautam Adani says It was a privilege By www.newkerala.com Published On :: Wed, 13 Nov 2024 17:42:02 +0530 Full Article
ma Public Sector Banks records strong performance in 1st half of FY25 By www.newkerala.com Published On :: Wed, 13 Nov 2024 17:50:02 +0530 Full Article
ma India will continue to be vocal about climate finances at COP29 By www.newkerala.com Published On :: Wed, 13 Nov 2024 17:52:02 +0530 Full Article
ma Integrated manufacturing cluster to be developed in Bihar's Gaya By www.newkerala.com Published On :: Wed, 13 Nov 2024 17:56:03 +0530 Full Article
ma India among top 10 countries in patents, trademarks, and industrial designs: WIPO 2024 report By www.newkerala.com Published On :: Wed, 13 Nov 2024 17:58:02 +0530 Full Article
ma India set to become 'major producer' of electric vehicles like China: Mark Mobius By www.newkerala.com Published On :: Wed, 13 Nov 2024 18:50:02 +0530 Full Article
ma Synthesis of highly condensed phospholes by Lewis acid-assisted dehydrogenative Mallory reaction under visible light irradiation By pubs.rsc.org Published On :: Chem. Sci., 2024, Accepted ManuscriptDOI: 10.1039/D4SC05657D, Edge Article Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Ikki Kamiyoshi, Yuki Kojima, Shibo Xu, Kosuke Yasui, Yuji Nishii, Koji HiranoA photo-promoted oxidative cyclization, that is, Mallory reaction of 2,3-diarylbenzophopholes has been developed. With an assistance of Bi(OTf)3 Lewis acid, the reaction proceeds smoothly under visible light irradiation even without...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ma $19 mn Loss & Damage funding pledged by Sweden at COP29, bringing total pledged funding to $720 mn By www.newkerala.com Published On :: Wed, 13 Nov 2024 16:12:02 +0530 Full Article
ma UP: Devotees celebrate 'Tulsi Vivah' at Balua Ghat in Prayagraj, marking sacred union of Lord Vishnu, Vrinda By www.newkerala.com Published On :: Wed, 13 Nov 2024 19:10:02 +0530 Full Article
ma Indian Coast Guard evacuates critically ill fisherman off Diu coast By www.newkerala.com Published On :: Wed, 13 Nov 2024 19:24:02 +0530 Full Article
ma Union Jal Shakti Minister CR Paatil chairs 13th high-powered review meeting of Brahmaputra Board By www.newkerala.com Published On :: Wed, 13 Nov 2024 19:34:02 +0530 Full Article
ma AI and hi-tech technologies will be used in CCTV arrangements: UP DGP Prashant Kumar on Mahakumbh 2025 preparations By www.newkerala.com Published On :: Wed, 13 Nov 2024 19:40:02 +0530 Full Article
ma DRDO conducts maiden flight test of Long-Range Land Attack Cruise Missile (LRLACM) By www.newkerala.com Published On :: Wed, 13 Nov 2024 19:44:02 +0530 Full Article
ma HC modifies the status quo order on maintaining constructions for Tent City in two islands of Lakshadweep By www.thehindu.com Published On :: Wed, 13 Nov 2024 19:14:08 +0530 Full Article Kochi
ma No gaps in management of biodegradable waste, Kerala tells NGT By www.thehindu.com Published On :: Wed, 13 Nov 2024 19:23:47 +0530 Full Article Kerala
ma HC quashes magistrate court’s directive to register FIR against police officers By www.thehindu.com Published On :: Wed, 13 Nov 2024 19:36:51 +0530 Magistrate court’s order to file FIR against police officers, including IPS officer and former Malappuram Superintendent of Police Sujith Das, in connection with an alleged sexual assault case quashed Full Article Kerala
ma French lower house rejects massively amended 2025 budget By www.thehindu.com Published On :: Wed, 13 Nov 2024 09:53:03 +0530 Prime Minister Michel Barnier's minority government now has a largely free hand in submitting a cleaned-up text to the Senate upper house Full Article World
ma Afghanistan attends U.N. climate talks for first time since Taliban return to power By www.thehindu.com Published On :: Wed, 13 Nov 2024 11:33:16 +0530 Afghanistan’s first delegation at United Nations climate talks since the Taliban’s return to power in 2021 has arrived in Baku, Azerbaijan Full Article Environment
ma Uzbekistan to make media, songs and films pass 'moral test' By www.thehindu.com Published On :: Wed, 13 Nov 2024 11:45:22 +0530 President Shavkat Mirziyoyev has introduced some reforms since coming to power after the 2016 death of dictator Islam Karimov, but rights groups say the country remains deeply authoritarian Full Article World
ma COP29: India, other developing countries demand fair climate finance commitments By www.thehindu.com Published On :: Wed, 13 Nov 2024 13:33:21 +0530 India, LMDCs advocate for equitable climate finance at COP29, pushing for transparency, fairness, and flexibility in financial commitments Full Article Environment
ma 5.3 magnitude earthquake jolts parts of Pakistan By www.thehindu.com Published On :: Wed, 13 Nov 2024 13:40:21 +0530 No casualties have been reported so far for the earthquake that had its epicentre around the Hindukush mountain range Full Article World
ma New ATP-competitive inhibitors of E. coli GyrB obtained from the mapping of the hydrophobic floor at the binding site: synthesis and biological evaluation By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3759-3777DOI: 10.1039/D4MD00498A, Research ArticleLucas Gutierrez, Peter Peršolja, Rodrigo Tosso, Nace Zidar, Danijel Kikelj, Ricardo D. EnrizA diagram of the active site of E. coli gyrase B, highlighting the hydrophobic subsite, including key residues relevant to ligand binding.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ma Discovery of hybrid Glypromate conjugates with neuroprotective activity against paraquat-induced toxicity By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3711-3727DOI: 10.1039/D4MD00584H, Research ArticleSara C. Silva-Reis, Vera M. Costa, Daniela Correia da Silva, David M. Pereira, Xavier Cruz Correia, Xerardo García-Mera, José E. Rodríguez-Borges, Ivo E. Sampaio-DiasA series of bicyclic-based Glypromate conjugates with reduction of protein aggregation elicited by Aβ25–35 and neuroprotective activity against paraquat-induced toxicity is reported, paving the way for the discovery of novel neurotherapeutics.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ma Fexinidazole optimization: enhancing anti-leishmanial profile, metabolic stability and hERG safety By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3837-3852DOI: 10.1039/D4MD00426D, Research ArticleAbdrrahman Shemsu Surur, Chin Fung Chan, Frieda-Marie Bartz, Iris L. K. Wong, Van T. D. Nguyen, Lukas Schulig, Andreas Link, Tak Hang Chan, Larry M. C. Chow, Patrick J. BednarskiStructure-guided optimization of fexinidazole led to analog (S)-51, a promising lead compound with superior activity, improved metabolic stability, and enhanced hERG safetyThe content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ma Asymmetric imidazole-4,5-dicarboxamide derivatives as SARS-CoV-2 main protease inhibitors: design, synthesis and biological evaluation By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3880-3888DOI: 10.1039/D4MD00414K, Research ArticlePhuong Nguyen Hoai Huynh, Phatcharin Khamplong, Minh-Hoang Phan, Thanh-Phuc Nguyen, Phuong Ngoc Lan Vu, Quang-Vinh Tang, Phumin Chamsodsai, Supaphorn Seetaha, Truong Lam Tuong, Thien Y. Vu, Duc-Duy Vo, Kiattawee Choowongkomon, Cam-Van T. VoNovel asymmetric imidazole-4,5-dicarboxamide derivatives were synthesized, evaluated for SARS-CoV-2 MPro inhibitory activity in vitro, and investigated for binding ability in silico.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ma Prediction of synergistic gemcitabine-based combination treatment through a novel tumor stemness biomarker NANOG in pancreatic cancer By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3853-3861DOI: 10.1039/D4MD00165F, Research ArticleJiongjia Cheng, Ting Zhu, Shaoxian Liu, Jiayu Zhou, Xiaofeng Wang, Guangxiang LiuThe synergistic effect observed in gemcitabine-based combination therapies targeting pancreatic cancer stem cells was correlated with the inhibiting effect on the expression of stemness-related gene NANOG.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ma Evaluating the therapeutic potential of genetically engineered probiotic Zbiotics (ZB183) for non-alcoholic steatohepatitis (NASH) management via modulation of the cGAS-STING pathway By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3817-3836DOI: 10.1039/D4MD00477A, Research ArticleMaha Saad, Walaa Ibrahim, Amany Helmy Hasanin, Aya Magdy Elyamany, Marwa MatboliZBiotics administration in the NASH model downregulated the RNA panel (MAPK3, EDN1, TNF, miR-6888-5p, lncRNA RABGAP1L-DT-206), restored intestinal barrier integrity, reduced hepatic inflammation, and improved lipid profiles and liver enzymes.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ma Correction: computational design, synthesis, and assessment of 3-(4-(4-(1,3,4-oxadiazol-2-yl)-1H-imidazol-2-yl)phenyl)-1,2,4-oxadiazole derivatives as effective epidermal growth factor receptor inhibitors: a prospective strategy for anticancer therapy By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3912-3912DOI: 10.1039/D4MD90040E, Correction Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Nilesh Raghunath Khedkar, Milind Sindkhedkar, Alex JosephThe content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ma Advances in Detecting Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) Using Molecular Receptors and Nanostructured Assemblies By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4MD00661E, Review ArticleAvijit Kumar DasThe detection and quantification of non-steroidal anti-inflammatory drugs (NSAIDs) are crucial due to their widespread use and potential impact on human health and the environment. This review provides a comprehensive...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ma IIT Madras to conduct two-day summit on extended reality By www.thehindu.com Published On :: Wed, 13 Nov 2024 13:19:23 +0530 The aim is to develop academic partnership programmes to boost research in XR or extended reality Full Article Chennai
ma Amaran is a film about a soldier’s life, nothing more: Seeman By www.thehindu.com Published On :: Wed, 13 Nov 2024 14:55:42 +0530 Full Article Tamil Nadu
ma Tamil Nadu CM Stalin to launch Phase II of nutritional intervention programme for malnourished children, mothers By www.thehindu.com Published On :: Wed, 13 Nov 2024 17:23:48 +0530 Mothers of over 76,700 babies in the age group of zero to six months, identified as malnourished, would be covered under Phase II of the programme Full Article Tamil Nadu
ma Rival Zomato's CEO congratulates Swiggy on stock market listing By www.thehindu.com Published On :: Wed, 13 Nov 2024 15:25:51 +0530 Swiggy got listed at ₹420, a jump of nearly 8% from the issue price on the NSE Full Article India
ma Wall Street makes wagers on the likely winners and losers in a second Trump term By www.thehindu.com Published On :: Wed, 13 Nov 2024 16:55:27 +0530 Wall Street is already making big bets on what take two for a White House led by Donald Trump will mean for the economy and markets Full Article Business
