vi Unhinged Liberal Women Cry On Social Media Over Trump’s Victory And Falsely Claim They’ve Lost All Their Rights By conservativefiringline.com Published On :: Sun, 10 Nov 2024 04:15:48 +0000 The following article, Unhinged Liberal Women Cry On Social Media Over Trump’s Victory And Falsely Claim They’ve Lost All Their Rights, was first published on Conservative Firing Line. (Natural News) Liberals have been working hard to portray Trump as a misogynist, and it worked on a lot of women – with some of them buying into the false narrative that he will work against women so wholeheartedly that they are now having very public meltdowns over his victory. Revolver put together some of the … Continue reading Unhinged Liberal Women Cry On Social Media Over Trump’s Victory And Falsely Claim They’ve Lost All Their Rights ... Full Article Politics democrats election liberals rights Trump unhinged victory women
vi GOP Rep. Luna Says ‘Criminal Prosecutions Necessary’ For Anti-Trump Lawfare Schemers In Government (Video) By conservativefiringline.com Published On :: Sun, 10 Nov 2024 20:15:48 +0000 The following article, GOP Rep. Luna Says ‘Criminal Prosecutions Necessary’ For Anti-Trump Lawfare Schemers In Government (Video), was first published on Conservative Firing Line. As President Donald Trump prepares to re-enter the White House after his landslide victory in Tuesday’s election, a U.S. congresswoman says “criminal prosecutions” are “necessary” for the government officials who have been promoting the massive lawfare campaign against the president-elect. On “Sunday Morning Futures” on the Fox News Channel, host Maria Bartiromo asked U.S. Rep. … Continue reading GOP Rep. Luna Says ‘Criminal Prosecutions Necessary’ For Anti-Trump Lawfare Schemers In Government (Video) ... Full Article Politics criminal Justice lawfare Luna prosecutions schemers Trump
vi Biden’s Corrupt FEMA Told Workers Not to Help Hurricane Victims Who Had Trump Signs By conservativefiringline.com Published On :: Mon, 11 Nov 2024 16:15:51 +0000 The following article, Biden’s Corrupt FEMA Told Workers Not to Help Hurricane Victims Who Had Trump Signs, was first published on Conservative Firing Line. Joe Biden’s corrupt Federal Emergency Management Administration (FEMA) has been caught telling its on-the-ground operatives not to help anyone with a Donald Trump campaign sign in their yard. The news broke late last week when a whistleblower revealed agency messages that told workers to refuse to help Trump supporters in the wake of Hurricane Milton … Continue reading Biden’s Corrupt FEMA Told Workers Not to Help Hurricane Victims Who Had Trump Signs ... Full Article Politics aid FEMA fired Florida Helene North Carolina Trump signs
vi Major Ruling In CNN Defamation Fight With James O’Keefe (Video) By conservativefiringline.com Published On :: Tue, 12 Nov 2024 18:15:00 +0000 The following article, Major Ruling In CNN Defamation Fight With James O’Keefe (Video), was first published on Conservative Firing Line. A federal appeals court has ruled against CNN in its attempt to have dismissed a defamation complaint from James O’Keefe and Project Veritas. O’Keefe launched Project Veritas and worked years with the organization, doing undercover interviews to uncover political scandals. He later left and now works with O’Keefe Media Group. But the dispute arose during … Continue reading Major Ruling In CNN Defamation Fight With James O’Keefe (Video) ... Full Article Politics CNN defamation lawsuit O'Keefe Veritas
vi Steve Bannon Issues 90-Second WARNING To Deep State At Trump Victory Party (Video) By conservativefiringline.com Published On :: Tue, 12 Nov 2024 20:15:31 +0000 The following article, Steve Bannon Issues 90-Second WARNING To Deep State At Trump Victory Party (Video), was first published on Conservative Firing Line. (Natural News) Steve Bannon, one of Donald Trump’s most fired-up supporters and allies all throughout the former president’s tumultuous political career, delivered a powerful speech after Trump’s victory warning the deep state that justice is coming. Fresh out of federal prison for his involvement in the events of Jan. 6, 2021, Bannon took the stage to deliver … Continue reading Steve Bannon Issues 90-Second WARNING To Deep State At Trump Victory Party (Video) ... Full Article Opinion Politics Bannon Cheney deep state January 6 Trump
vi Left Already Losing It As Trump Announces Starting Lineup (Video) By conservativefiringline.com Published On :: Tue, 12 Nov 2024 22:15:17 +0000 The following article, Left Already Losing It As Trump Announces Starting Lineup (Video), was first published on Conservative Firing Line. Trump learned some hard lessons from his first kick at the can. This time, he’s not making the same mistakes. Personnel IS policy. Last time around DJT was hamstrung right out of the gate when the Alabama Senator he tapped to be his AG was stuck in purgatory under bogus Russia allegations. The Deep State … Continue reading Left Already Losing It As Trump Announces Starting Lineup (Video) ... Full Article Opinion Politics administration appointments Biden Harris Homan Miller Senate Trump
vi Video: Merlin's Time & Attention Talk (Improvised Rutgers Edition) By www.43folders.com Published On :: Tue, 27 Apr 2010 19:57:09 +0000 Video: Merlin Mann - "Time & Attention Talk (improvised)" Audio (mp3): "Merlin Mann - 'Rutgers Time & Attention Talk'" This is a talk I did at Rutgers earlier this month. I kinda like it, but for a weird reason. Something something, perfect storm of technology Ragnarok, and yadda yadda, I had to start the talk 20 minutes late with no slides. Nothing. So, I riffed. And, I ended up talking about a lot of the new stuff you can expect to see in the Inbox Zero book—work culture, managing expectations, the 3 deadly qualities of email, and one surprising reason email's not as much fun as Project Runway. Some people liked it. I think. I liked it. I hope you do, too. Here's the slides I would have shown. ;-) Who Moved My Brain? Revaluing Time & Attention Many thanks, again, to my great pal, Dr. Donald Schaffner, for bringing me in for this visit. I had a great time and met some fantastic, passionate people. Much appreciated. Hey—know anybody who should hear this talk? Hmmm? I’ll bet. Lucky you, you can hire me to deliver this or any of my other talks to the time- and attention-addled people you work with as well. Current topics include email, meetings, social media, and future-proofing your passion. Drop a note if you have an upcoming event where you think we two might be a good fit. update 2010-04-27_13-50-00 Apologies—my friends at Rutgers (inexplicably) have placed this video under lock and key. Fortunately, I have a lock-picker called Firefox. Samizdat video available soon... update 2010-04-27_14-42-24 Yay, fixed! Many thanks to my hero, Jesse Schibilia. ”Video: Merlin's Time & Attention Talk (Improvised Rutgers Edition)” was written by Merlin Mann for 43Folders.com and was originally posted on April 27, 2010. Except as noted, it's ©2010 Merlin Mann and licensed for reuse under CC BY-NC-ND 3.0. "Why a footer?" Full Article Time and Attention Videos world of work
vi Video: "Broken Meetings (and how you'll fix them)" By www.43folders.com Published On :: Wed, 06 Oct 2010 19:40:08 +0000 A couple weeks ago, my pals at Twitter were kind enough to invite me in to visit with their (rapidly growing) team. The topic was meetings, so I used it as an opportunity to publicly premiere a talk I've been presenting to private clients over the past few months. I hope you'll enjoy, Broken Meetings (and how you'll fix them). Slides: Supplementary links and commentary forthcoming, but I wanted to go ahead and post the talk as quickly as the video was available. Special thanks to Michelle, Jeremy, and the crackerjack Twitter crew for a swell afternoon. I really like this talk and sincerely hope you will find it useful in helping to un-break your own meetings. ”Video: "Broken Meetings (and how you'll fix them)"” was written by Merlin Mann for 43Folders.com and was originally posted on October 06, 2010. Except as noted, it's ©2010 Merlin Mann and licensed for reuse under CC BY-NC-ND 3.0. "Why a footer?" Full Article Meetings Merlin Speaking Twitter Videos world of work
vi Video: John Roderick on String Art Owls, Copper Pipe, and Bono's Boss By www.43folders.com Published On :: Fri, 21 Jan 2011 18:51:26 +0000 [jump to video] Long story (not very) short? One night in 2003--after killing it in front of audience of about 30 lucky people in Oakland--The Long Winters needed a place to crash, and my wife and I were happy to oblige. So, they drove their Big Stinky Blue Van over the bridge, slept on our floor, and by breakfast the next morning, it'd become clear to me that I'd provided lodging to a man who was not only very likely a member of my karass--he was also one of the smartest bullshit artists I'd ever met. Almost eight years later, although I don't see him nearly as much as I'd like, I still count the guy as one of my best pals ever. That's John Roderick. And, I think you need to know about him. John doesn't read this site--he's more of a Twitter person--so I don't risk feeding his astounding excess of dignity by saying he's one of the most gifted writers and bon vivants of our generation. He's just the best. In large part because he's congenitally incapable of suffering bullshit. This was never more apparent than the Saturday morning in 2007 when we sat in my back yard and talked about a lot of stuff. Playing guitar, advertising on the web, the evil work of promoters, and why everyone is always trying to shortchange everyone on copper pipe. That talking became a four-part interview I ran on the late and occasionally lamented The Merlin Show, and, to this day, it's one of my favorite things I've been lucky enough to post to the web. So, y'know how I'm definitely "not for everyone?" Well, John is really "not for everyone." He's opinionated and arrogant and undiplomatic and unironically loves Judas Priest--meaning everyone will find at least one thing not to like about him. Despite being hairy and enjoying laying on your bed, John is not exactly a teddy bear. But, John's also right a lot. And, he never sands off the edges of his personality or opinions to make you theoretically "like" him. Which, it will come as no surprise to you, is a big reason I love the guy more than a free prime rib dinner. So, why the jizzfest about that awful jerk, John Roderick? Because, as I noted the other day on the Twitter, in our first episode of Back to Work I misattributed a line that should have been credited to John. Which in itself is unimportant, except inasmuch as finding that link to correct the error got me watching our 50-some minutes of chatting again. I also received some at-responses and emails that reminded me how much people enjoyed our chat. But, really it made me realize how much that rambling morning in my back yard still resonates so much with stuff I care a lot about. Independence. Agency. Directness. And, never apologizing for wanting to get paid. Also, guitars and talkative hippies. So, anyway. John. I edited all four parts of the video into one big (streamable/downloadable) movie that should make it way easier to watch at a sitting. Should that interest you. Which it may not. Which, as ever, is totally fine, and kind of the point. But. If you like Dan and my new show (and, seriously—God bless you magnificent bastards who helped briefly make B2W the most popular podcast in the world [gulp]), I think you'll really like this interview a lot too. I hope so, anyway. Thus, submitted for your disapproval, permit me to present my four-year-old visit with the acerbic, opinionated, and reportedly unlikeable bullshit artist whom I respect and adore more than just about anybody. Meet Hotrod. Vimeo Page Direct Download Link (589 mb, requires login) ”Video: John Roderick on String Art Owls, Copper Pipe, and Bono's Boss” was written by Merlin Mann for 43Folders.com and was originally posted on January 21, 2011. Except as noted, it's ©2010 Merlin Mann and licensed for reuse under CC BY-NC-ND 3.0. "Why a footer?" Full Article Brady's Bits John Roderick The Merlin Show video
vi Nerdiest Interview Ever: MPU Workflows Part II By www.43folders.com Published On :: Sun, 27 Mar 2011 20:34:26 +0000 MPU 046: Workflows with Merlin Mann II « Mac Power Users Download MP3 Huffduff It I have the life that I have because I've made a lot of weird decisions, and they've worked out well. Not gonna lie to you. I'm a huge nerd. Surprised? Yep. I can recite big chunks of The Big Lebowski from memory. I can argue for an hour on the merits of Dick York over Dick Sargent. And, I can—and frequently do—catch myself thinking Catwoman, Batgirl, Princess Leia, and Emma Peel should have a light-hearted pillow fight that ends with an hour of genial french-kissing. Pretty much like you, probably. I dunno, maybe your version includes Kitty Pryde. Po-tay-to/Po-taht-o, right? Perhaps most saliently, by virtue of having spent a solid 2,399 days as a Fake Productivity Guru, I have been provided with an unquestionably Janusian monkey's paw of a gift; I now know a lot about workflows. Nerdy, nerdy workflows. I can tell you a few things that almost always work, I can tell you a handful of things that almost never work, and—best or worst of all—I can tell you thousands of things that might work. Sometimes. Maybe. Kinda. For some people. For now. And, at the risk of gay-marrying my arrogance to my hypocrisy, I can tell you that I also know enough about the unholy diarrhea of potential options for Theoretical Productivity to share two big patterns: Getting your workflow right matters. Getting your workflow right to the exclusion of the actual work is a fool's game. But. Managing to get the most useful and most elegant and least fiddly mix of 1 and 2 right is super-hard. Especially for nerds. Especially for me. So, as I type this today, I believe there can be no greater testament to these claims—or, at least, no greater place to test the veracity of these claims for yourself—than in this TWO AND A HALF HOUR-long interview for Mac Power Users. It is reeeeeeeeally nerdy. Almost intolerably nerdy. Just…overwhelmingly nerdy. But, man, is it ever really good, and really fat with the most insanely granular details of How I Work. Lo, even these 928.5 days after officially retiring from productivity pr0n, my desire to not "vend stroke material for your joyless addiction to puns about procrastination and systems for generating more taxonomically satisfying meta-work" is tempered by a (widely under-reported) practical streak. Yes: I continue to despise empty advice about rearranging deck chairs on The Titanic. But, yes: I do also still very much enjoy talking about how all the tips and tricks can or can't work in the context of work you care about. That matters. It really does. So. Here goes. A one hundred and forty six minute-long, Joyce-ian amble through the Big Stuff and the Little Stuff. David and Katie were very patient. How I name text files. Why I break iOS apps. Why I love the letter "x." Why I won't row out to islands any more. How a 115,000 word book manuscript is "like a house full of confederate money." How "The Cloud" broke in New Zealand. How I use MultiMarkdown, Scrivener, TextExpander, OmniFocus, TextMate, Notational Velocity, Dropbox, and an explosive combination of Elements, Notesy, Nebulous, Simplenote, CF Outliner, iThoughts, Instacast, Good Reader, and wow wow wow. How I try not to fiddle—how I sometimes succeed and often don't. But, how I try. Anyhow. There you go. A perfectly nerdy bookend to last year's first Magnum Opus MPU interview on these same topics, Mac Power Users Episode 46 is just insanely nerdy. And, what have you. I hope you like it. I hope it's useful. I hope you don't use it to replace real work. And, as ever, I really hope Batgirl starts having more sexy pillow fights. Enjoy. And, God save you. MPU 046: Workflows with Merlin Mann II « Mac Power Users Download MP3 Huffduff It ”Nerdiest Interview Ever: MPU Workflows Part II” was written by Merlin Mann for 43Folders.com and was originally posted on March 27, 2011. Except as noted, it's ©2010 Merlin Mann and licensed for reuse under CC BY-NC-ND 3.0. "Why a footer?" Full Article Elsewhere Interviews Productivity Pr0n Workflows
vi Visiting Locorotondo, Italy – A Guide to the Trulli Town By www.adventurouskate.com Published On :: Wed, 21 Aug 2024 15:59:03 +0000 Have you heard of Locorotondo, Italy? Locorotondo is one of Southern Italy’s most beautiful villages, in my opinion, but it isn’t yet overwhelmed with tourist crowds. A true hidden gem, Locorotondo is just a 12-minute drive from busy Alberobello in the Puglia region, but feels like a world away. Planning your trip to Locorotondo last […] The post Visiting Locorotondo, Italy – A Guide to the Trulli Town appeared first on Adventurous Kate. Full Article Italy puglia
vi What’s SearchGPT Really About? Moving Past the Training Data Dilemma. By battellemedia.com Published On :: Fri, 26 Jul 2024 14:18:26 +0000 This morning we awoke to one story dominating the tech news landscape: OpenAI is “expanding into search,” launching SearchGPT, a prototype that appears to be a direct competitor to Google (and Bing and Perplexity, not that they really matter). But despite the voluminous coverage, my initial take is that once the hype cycle passes – … Continue reading "What’s SearchGPT Really About? Moving Past the Training Data Dilemma." Full Article AI Future of Search Internet Big Five Joints After Midnight & Rants Media/Tech Business Models ai media publishing search
vi OOPS: SNL Tried To Help Kamala… But Boosted TRUMP Instead (VIDEO) By clashdaily.com Published On :: Mon, 04 Nov 2024 10:40:07 +0000 It was supposed to be a push to help her over the finish line. It ended up giving Trump a free shot with their audience instead. The post OOPS: SNL Tried To Help Kamala… But Boosted TRUMP Instead (VIDEO) appeared first on Clash Daily. Full Article Videos
vi WATCH: Vivek Puts On A Clinic… Flips Bro From Kamala To MAGA In Just A Few Questions (VIDEO) By clashdaily.com Published On :: Tue, 05 Nov 2024 10:00:52 +0000 When he first showed up, he was echoing the Jan-6-threat-to-democracy talking point. By the time he left, he had other considerations to chew over. The post WATCH: Vivek Puts On A Clinic… Flips Bro From Kamala To MAGA In Just A Few Questions (VIDEO) appeared first on Clash Daily. Full Article Videos
vi Convicted Jihadi Terrorist Hired As Social Justice Prof In Western University By clashdaily.com Published On :: Wed, 06 Nov 2024 04:39:39 +0000 For anyone thinking that 'social justice' is less about 'justice' and more about being a delivery system for a poisoned ideology, the story of Dr Hassan Diab, is the proverbial 'Exhibit A'. The post Convicted Jihadi Terrorist Hired As Social Justice Prof In Western University appeared first on Clash Daily. Full Article News Clash
vi TRUMP TRIUMPHS: Victory Speech As He Completes The YUGE Comeback By clashdaily.com Published On :: Wed, 06 Nov 2024 13:12:14 +0000 Trump asked the question: are you better now than when I was in office? America's answer could not have been more clear. The post TRUMP TRIUMPHS: Victory Speech As He Completes The YUGE Comeback appeared first on Clash Daily. Full Article Videos
vi WATCH: Carville Has NO ‘Effs’ Left To Give — Blasts ‘Woke’ In Epic ‘I Told You So’ Rant By clashdaily.com Published On :: Tue, 12 Nov 2024 10:10:59 +0000 One of the best parts about the first days after a Trump win is how the left has begun to devour themselves. The post WATCH: Carville Has NO ‘Effs’ Left To Give — Blasts ‘Woke’ In Epic ‘I Told You So’ Rant appeared first on Clash Daily. Full Article Videos
vi Left Already Losing It As Trump Announces His Starting Lineup (VIDEO) By clashdaily.com Published On :: Tue, 12 Nov 2024 10:20:30 +0000 He learned some hard lessons from his first kick at the can. This time, he's not making the same mistakes. Personnel IS policy. The post Left Already Losing It As Trump Announces His Starting Lineup (VIDEO) appeared first on Clash Daily. Full Article News Clash
vi Footage of Jill Biden and Kamala Harris Sitting Side-by-Side at Veterans Day Event Goes Viral By www.westernjournal.com Published On :: Mon, 11 Nov 2024 23:03:57 +0000 There appeared to be a definite frost between first lady Jill Biden and Vice President Kamala Harris during a Veterans Day event at Arlington National Cemetery on Monday. A close-up […] The post Footage of Jill Biden and Kamala Harris Sitting Side-by-Side at Veterans Day Event Goes Viral appeared first on The Western Journal. Full Article Commentary 2024 election Jill Biden Joe Biden Kamala Harris Veterans Day
vi Insult to Injury: MSNBC and CNN Suffer Staggering Ratings Plunge Following Trump Victory By www.westernjournal.com Published On :: Tue, 12 Nov 2024 14:25:40 +0000 Left-wing networks had plenty of bad news for their viewers as former President Donald Trump stormed to victory in the Nov. 5 election. Now, they’re getting plenty of bad news […] The post Insult to Injury: MSNBC and CNN Suffer Staggering Ratings Plunge Following Trump Victory appeared first on The Western Journal. Full Article News 2024 election CNN Donald Trump Fox & Friends Liberal media Media watch MSNBC Politics U.S. News
vi CNN Host Reportedly Leaving Network After Short-Lived Stay: His Career Change Is Completely Absurd By www.westernjournal.com Published On :: Tue, 12 Nov 2024 14:42:13 +0000 Three years ago, Chris Wallace walked away from Fox News over concerns that those at the “Fair and Balanced” network were beginning to, as he put it, “question the truth.” […] The post CNN Host Reportedly Leaving Network After Short-Lived Stay: His Career Change Is Completely Absurd appeared first on The Western Journal. Full Article Commentary Chris Wallace CNN Establishment media Fox News Social media
vi Flashback: Video of Tom Homan Taking Down AOC Resurfaces, Showing Why Trump Picked Him By www.westernjournal.com Published On :: Tue, 12 Nov 2024 15:27:01 +0000 Shortly after President-elect Donald Trump appointed Tom Homan as “border czar,” the immigration hardliner’s hilarious 2019 smackdown of Democratic Rep. Alexandria Ocasio-Cortez of New York went viral on social media. […] The post Flashback: Video of Tom Homan Taking Down AOC Resurfaces, Showing Why Trump Picked Him appeared first on The Western Journal. Full Article Commentary Alexandria Ocasio-Cortez Border crisis Border security Donald Trump Illegal immigration Trump administration
vi Democratic Politician Crashes Her Car While Allegedly Drunk, Hurls Vile Insults at Responding Officer: Police Report By www.westernjournal.com Published On :: Tue, 12 Nov 2024 21:35:14 +0000 A Chicago-area Democrat hurled an insult at police Sunday after being charged with drunken driving, according to local news reports. Samantha Steele represents the Second District on the Cook County […] The post Democratic Politician Crashes Her Car While Allegedly Drunk, Hurls Vile Insults at Responding Officer: Police Report appeared first on The Western Journal. Full Article News Alcohol Chicago Democrats Investigation Police U.S. News
vi Sport | Boks will be Boks while evolving attack under Brown: 'I won't teach us to play like All Blacks' By www.news24.com Published On :: Tuesday Nov 12 2024 22:03:44 The Springboks will continue to evolve their attack, but they must do so within the framework of what has made them so successful, says attack coach Tony Brown. Full Article
vi Sport | Makgopa's rise evidence of Broos' Bafana impact: 'You don't want to disappoint such a person' By www.news24.com Published On :: Wednesday Nov 13 2024 05:00:31 Evidence Makgopa wore a sheepish smile when Bafana Bafana coach Hugo Broos showered him with praise before literally patting the forward on the back, making him blush at Dobsonville Stadium. Full Article
vi Sport | BIG PREVIEW | SA v India: Jansen wary of India's blazing batters as Centurion run fest awaits By www.news24.com Published On :: Wednesday Nov 13 2024 05:01:33 Wednesday's third T20 between South Africa and India at SuperSport Park in Centurion is shaping up to be a run-drenched one, especially if the weather holds and SA's bowling centre doesn't. Full Article
vi French mention of Farahat’s Book: Iran : « Femme, vie, liberté ! » By cynthiafarahat.com Published On :: Mon, 17 Oct 2022 21:32:11 +0000 By JEAN-PIERRE LLEDO MABATIM Oct. 16, 2022 Toutes les informations qui nous parviennent d’Iran nous disent que cette nouvelle révolte est totalement inédite. Elle se distingue de toutes les précédentes parce que ce sont les femmes qui en ont pris l’initiative et plus encore parce que ce qui est ciblé n’est pas seulement le pouvoir, […] Full Article Featured Articles
vi Farahat’s Arabic Book Review in Mekka Newspaper By cynthiafarahat.com Published On :: Sun, 30 Oct 2022 15:23:58 +0000 Mekka Newspaper, Mecca, Saudi Arabia: Oct. 28, 2022 It was my distinct honor to Arabic receive a wonderful review by Mecca Newspaper, one of the oldest newspapers in the Middle East. I am deeply grateful and humbled to be part of the historic reformation and renaissance taking place in the Middle East. When Mecca newspaper […] Full Article Featured Articles
vi Egyptian Government Television Episode About Farahat’s Book By cynthiafarahat.com Published On :: Mon, 31 Oct 2022 13:25:24 +0000 Cairo, Egypt Oct. 28, 2022 On Egyptian TV show, “Headlines,” Dr. Hossam Farouk dedicated an episode to discussing national and international coverage of the Secret Apparatus: The Muslim Brotherhood’s Industry of Death. It was a great honor having the book featured on this great show. Full Article Featured Articles
vi The Secret Apparatus Book Review: Conspiracy? Yes, A Century of Muslim Brotherhood Jihad By cynthiafarahat.com Published On :: Sat, 10 Dec 2022 15:53:06 +0000 By Walter Donway, Savvy Street originally published on Dec. 4, 2022 Book Review: The Secret Apparatus: The Muslim Brotherhood’s Industry of Death by Cynthia Farahat, Post Hill Press, Bombardier Books (2022) A grim irony of twentieth-century history (but, of course, also predating it) is that the most horrendous threats to humanity have simply been too monstrously evil […] Full Article 9/11 Academia Afghanistan Al-Azhar University Al-Qaeda CAIR Infiltration Muslim Brotherhood
vi Farahat’s Interview with FDD By cynthiafarahat.com Published On :: Wed, 11 Jan 2023 12:42:02 +0000 FDD’s Foreign Podicy Podcast with Cynthia Farahat Dec. 27, 2022 The Muslim Brotherhood has been around for close to a century but most people – certainly most Americans and Europeans – know very little about it. Is it reformist and non-violent as its spokesmen and defenders claim? Or is it – as Cynthia Farahat argues in a […] Full Article Featured Articles
vi Commentary: Secret Service Agents Placed on Leave After Trump Assassination Attempt By deneenborelli.com Published On :: Fri, 23 Aug 2024 19:57:50 +0000 Commentary by Susan Crabtree originally published by RealClearPolitics and RealClearWire Three weeks ago, Acting Secret Service Director Ronald Rowe angrily pushed back on senators’ calls to immediately fire or discipline key agents directly responsible for the security failures that led to the assassination attempt against former President Trump at last month’s campaign rally in Butler, … Full Article Commentaries News
vi Commentary: Harris Pushed To Explain Policy Shifts in First Interview as Dem Nominee By deneenborelli.com Published On :: Fri, 30 Aug 2024 15:47:39 +0000 Commentary by Philip Wegmann originally published by RealClearPolitics and RealClearWire Kamala Harris shrugged. Asked about former President Donald Trump’s questioning of her racial identity, the vice president replied, “Same old, tired playbook. Next question, please.” And then she laughed. “That’s it?” protested CNN’s Dana Bash, probing for more during the first sit-down interview with the … Full Article Commentaries Government Policies News
vi Commentary: Second Assassination Attempt Forces New Reckoning for Trump, Secret Service By deneenborelli.com Published On :: Tue, 17 Sep 2024 14:23:52 +0000 Commentary by Susan Crabtree and Philip Wegmann originally published by The second assassination attempt against former President Donald Trump while he was golfing at one of his Florida courses on Sunday is forcing the United States Secret Service to further tighten security around the Republican presidential nominee and to reevaluate just how much Trump should … Full Article Commentaries News
vi Interview: Steve Brooking By www.chathamhouse.org Published On :: Tue, 27 Sep 2022 18:35:28 +0000 Interview: Steve Brooking The World Today mhiggins.drupal 27 September 2022 The Afghanistan expert tells Mike Higgins the Taliban are reneging on their promises and that the region’s powers must intercede. Steve Brooking is the former chargé d’affaires at the British Embassy in Kabul and was special adviser to the UN Assistance Mission in Afghanistan from 2015 to 2021. How has day-to-day life become worse for Afghans since the United States and its allies withdrew abruptly from Afghanistan in the late summer of 2021? That depends on where those Afghans are living and what they were doing. Life for lots of ordinary rural Afghans hasn’t changed much, it is still subsistence farming. Until last year, the success stories of girls in education, new hospitals, schools and clinics were concentrated in the towns and cities. When the Americans left, there was a mass exodus of the educated middle class In fact, there has been a shortage of teachers and medics for years. Many Afghans left those jobs to work for the coalition forces or the international development presence in the country. When the Americans left last year, along with them was a mass exodus of the educated middle class from the country, which affected the cities and towns. The emerging middle class was also hit by the disappearance of the jobs that went with those foreign troops. Spending power has collapsed. Many Afghans in cities support a dozen or more extended family members, but now they don’t have the money. Afghans are relying on external humanitarian aid but the agencies are only getting about half what they are asking for because there are competing humanitarian crises – in the Horn of Africa, Syria, Ukraine. In September, Washington announced it would transfer $3.5 billion into a Swiss-based trust fund to try to stabilize Afghanistan. How far will that money go and are the US wise to avoid Afghanistan’s central bank? It is enough to make a significant humanitarian difference. Bypassing the Afghan central bank indicates that the US government is keen the money does not fall into the hands of the Taliban, or international terrorists. The American assassination of the Al-Qaeda leader, Ayman al-Zawahiri, in Kabul in July showed the Taliban have not kept to their promise to prevent the country being used as a terrorist base. Also, it is clear the US doesn’t want to be seen to be supporting the Taliban government or to start recognizing it or getting anywhere near recognizing it. It remains concerned about all sorts of violations of basic rights – the most egregious being girls not allowed in secondary schools and women not being allowed to work except in certain sectors. The Americans and other donor countries were paying teachers’ salaries through the UN but that stopped when the new Afghan school year began in March and girls still weren’t allowed back to school. The Taliban need to show a responsible level of governance and ability before people will trust them with their money. But it’s difficult to see the Taliban making the necessary concessions to move beyond humanitarian aid to receive development funding. As the attention of the US is focused on Ukraine and further eastwards towards China, what will be the cost if the West doesn’t engage with Afghanistan seriously? You could argue the costs will be minimal. The Americans tried a lot over 20 years, they failed and then left overnight. It caused complete shock around the region. To be fair, though, the Americans warned the region’s powers that they were leaving and that this would be a problem in the region unless they got help from those same powers. The Taliban complain about sanctions, travel restrictions and the freezing of assets. But they have made no attempt to honour the Doha Agreement Europe and the UK are more likely to experience the fallout from a deteriorating Afghanistan. The refugee flows will continue. To stem that, they want to persuade the Taliban to make a more inclusive government. There are few levers to pull with the Taliban, unfortunately. They complain about sanctions, travel restrictions for various leaders, the freezing of assets. But they haven’t made any attempt to speak to the political opposition or honour the terms of the Doha Agreement, let alone engage in other issues. I think the onus to act falls on the regional powers because they will feel the first effects of instability in Afghanistan. China, Russia, India and other regional powers are members of the Shanghai Cooperation Organization (SCO), which had its summit in Samarkand last month. Some have been arguing that the SCO should take a more active role in Afghanistan, which has SCO observer status. Iran is worried about the persecution of Shia minorities in Afghanistan, but they are trying to have constructive relations with the Taliban because they need water from Afghanistan to feed the southeast of Iran, which is very dry. Pakistan has not been able to control the Taliban, but has succeeded in establishing a regime in Kabul that is hostile to India. China would like to see stability in Afghanistan to access its natural resources, but otherwise it largely follows Pakistan’s lead. Russia is preoccupied with Ukraine, but is worried about the spread of narcotics and Islamic extremism up through central Asian states. None of those regional powers, it should be said, is willing to recognize a Taliban government. How secure is the Taliban government? Cross-border trade continues, with revenues from mining, timber, coal and natural resources. The Taliban are still involved in heroin production, which they tax heavily despite having said they would suppress it. A senior Afghan woman told me recently: ‘We feel more secure, but less certain about our future than ever before.’ They don’t want to upset the poppy farmers who helped return them to power. There is a level of security that has bought the Taliban some time. Previously, in the south there was a lot of fighting and there were daily car bombs and attacks in some cities. Now, on the whole, mothers know they can send their kids to the water pump. A friend, a senior Afghan female in the country, told me recently: ‘We feel more secure, but less certain about our future than ever before.’ They can see that the economy is going downhill. One scenario is a disintegration of the country along regional lines, in which, say, the people of Badakhshan decide they will no longer let the central government take all the revenue from their lapis lazuli and ruby mines. Local warlords may re-emerge whom the Taliban would find it more difficult to deal with. As for the terrorist threat in Afghanistan, the Taliban never broke their ties to Al-Qaeda, and at one point the Americans were saying that there were more than two dozen terrorist groups in Afghanistan. I’m sure the Taliban will be able to rein in most of these, the exception being Islamic State – that is a battle of extreme ideologies. Another problem is a lot of these international terrorists have married Afghans and are now well enmeshed into local society. You paint a bleak picture of Afghanistan’s future. What, if anything, gives you hope for the country? Ordinary Afghans are resilient and entrepreneurial. They also have a strong sense of being Afghan and that their country is one of the longest-existing countries in that part of the world. But the Taliban need to make people feel they are included in that national identity. Sadly, I think it will take war, famine, plague and disaster in order for the Taliban to unbend sufficiently to realize that they need better ethnic and gender representation in government, as well as economic expertise. I hope the Afghan diaspora will be asked to come together to forge a better future for the country. Full Article
vi Book preview: Guide to Chinese Climate Policy 2022 By www.chathamhouse.org Published On :: Wed, 28 Sep 2022 15:52:14 +0000 Book preview: Guide to Chinese Climate Policy 2022 20 October 2022 — 10:00AM TO 11:15AM Anonymous (not verified) 28 September 2022 Chatham House and Online Join authors David Sandalow and Michal Meidan to discuss their upcoming book. China is the world’s largest emitter of greenhouse gases and a key player in tackling the global climate crisis. Its stated climate policies, namely its high-level targets to peak emissions by 2030 and to achieve carbon neutrality by 2060, are significant. But while national-level ministries, local governments and businesses are setting climate roadmaps, implementation is challenging at times. In the current context of the global energy market and geopolitical turmoil, China’s need to maintain energy security can seem at odds with its climate pledges. The authors will present the book, which examines Chinese emissions, the impacts of climate change in China, as well as China’s domestic and international climate change policies and the main implementation challenges these policies face. Full Article
vi The G20 will survive but needs major repair By www.chathamhouse.org Published On :: Tue, 15 Nov 2022 11:57:21 +0000 The G20 will survive but needs major repair Expert comment NCapeling 15 November 2022 Russia’s attack on Ukraine is the biggest challenge to the existence of the G20 since its foundation. The leader-level version of the G20 was founded in 2008 to coordinate the international response to the global financial crisis across advanced and major emerging economies. At the outset it was judged a great success. The 2009 London Summit demonstrated a high degree of unity among the world’s largest economies on a comprehensive action plan to tackle the crisis. The group’s subsequent performance has disappointed. Particularly during the pandemic and the Donald Trump presidency in the US, the group made only a limited additional contribution to policies which national governments were pursuing in any case. The existing G20 approach for tackling debt distress in low-income countries, the ‘Common Framework’, is progressing far too slowly Nonetheless, its members continued to see it as an essential forum without which it would be even harder to tackle a growing list of global economic challenges. This faith was partly repaid when, following the election of the Joe Biden administration in the US, agreement was reached on the $650 billion special drawing rights (SDR) general allocation by the International Monetary Fund (IMF) in summer 2021. Impact of the war in Ukraine Following Russia’s attack on Ukraine earlier this year, leading western members of the group called for Russia to be suspended from the G20 as Russia’s action ran directly against the key principles of the rules-based international system on which the G20 was founded. Western countries also walked out of meetings of the G20 Finance Ministers’ and International Monetary and Financial Committee this spring rather than sit at the same table as Russian representatives. This contrasted with 2014 when Russia was suspended indefinitely from the G7 for its takeover of Crimea but no action was taken against it in the G20. However, China and India, supported by several other emerging economies declined to suspend Russia, creating a standoff which could have resulted in a rapid collapse of the G20, particularly as its informal structure means that, in contrast to the international financial institutions (IFIs), there are no legal principles or procedures to determine how to address such a situation. It appears the West has now concluded (rightly) that the G20 is too important as a forum for working with China and the other major emerging economies to be allowed to disappear. This is likely to be because there are no straightforward alternatives. The G7 is too narrow to fill the role and China is now highly unlikely to attend a future G7 Summit as a guest. The boards of the IFIs are not equipped to coordinate across institutions, which is a vital role of the G20, and the United Nations (UN) system does not offer the scope, speed, leader-level engagement, or flexibility of the G20. Moreover, as evidenced by the chair’s summary of the third G20 Finance Ministers’ and Central Bank Governors’ meeting in July, once the group gets past the dispute over how to handle Russia, there is a worthwhile agenda of issues which can be agreed on. Russia is unlikely to play a disruptive role as preserving its membership of the group will be its key objective, and it will not want to undermine support among other emerging economies As the 2022 president of the G20, Indonesia has been determined to produce a final communique for the leaders’ summit and it looks increasingly like this will be achieved, even though it was impossible to agree concluding statements for some earlier G20 ministerial meetings. The key will be to deal with the differences over Ukraine between the West and emerging economies with a short opening paragraph reflecting both views. This would then be followed by a consensus text on all the areas where the two groups do agree. Russia is unlikely to play a disruptive role as preserving its membership of the group will be its key objective, and it will not want to undermine support among other emerging economies by blocking issues that all agree on. However, even with a final communique achieved, returning to a fully functioning agenda setting, coordination, and decision-making role for G20 will be very challenging, particularly while the war in Ukraine continues. Tackling sovereign debt distress should be a top priority There are critically important issues on which G20 action is urgently needed. Top of the list is the acute problem of sovereign debt distress. Some 60 per cent of low-income countries are now judged to be in debt distress or at high risk of debt distress. But the existing G20 approach for tackling debt distress in low-income countries, the ‘Common Framework’, is progressing far too slowly, and there is no agreed mechanism for handling the growing list of emerging economies in debt distress. Without tackling debt distress, it is extremely hard to see how it will be possible to generate the vast flow of private sector climate finance necessary to help the developing world progress to net zero. And yet the G20 is one of the few forums in which a high-level approach to debt distress can be defined because China – along with the IFIs and the western-based private sector – is a key player in any solution. Urgent repairs needed However, there is a critical lack of trust among G20 participants which, although in part a reflection of the disagreements over handling Russia, is also about longer-term factors such as the growing geopolitical tensions between China and the US on trade and investment in high tech. An example of how this has played out was the action China and India took at the Rome G20 Summit in 2021 in blocking Italy’s efforts to establish a new ministerial task force designed to address the threat of future pandemics – a subject which all G20 countries agree is important. Full Article
vi China’s zero-COVID cannot continue, reopening is needed By www.chathamhouse.org Published On :: Thu, 01 Dec 2022 11:16:46 +0000 China’s zero-COVID cannot continue, reopening is needed Expert comment NCapeling 1 December 2022 Unsure of how to loosen rules, local officials have doubled down on severe restrictions behind so much economic damage. Reopening will quell public anger. When President Xi Jinping was seen unmasked at the G20 summit in Indonesia, he maintained a largely positive tone with President Joe Biden and other world leaders. This left an impression that China was on the verge of withdrawing its zero-COVID strategy. A set of loosening policy measures introduced by Beijing seemed to further suggest that China was on track to reopen. As outlined in the 20th party congress, Xi wants to forge a pathway towards economic modernization and this means building economic resilience and a further increase in household incomes. However, a series of displays of public defiance against the government’s zero-COVID policy has left the rest of the world perplexed. Some loosening of restrictions announced on 11 November by the central government, with the number of new cases still rising rapidly, left the provincial governments in confusion as to which direction to turn. Absolute political loyalty The persistent slogan of ‘zero-COVID’ was in stark contrast to the slackening of restrictions. Local officials decided to double down on stringent COVID measures as a way of displaying absolute political loyalty to the top, which inevitably caused daily agonies among large parts of the Chinese population. The strategy has intensified economic pressures, exacerbated rising levels of youth unemployment, and tested the patience of the entire country This decision-making process sheds some light on the way the Chinese bureaucracy approaches crises at a time when the party leadership is tightening political control. Lower-level officials avoided making important decisions and instead decided to wait for instructions from the top. As the rules were unclear, they implemented policies according to past precedents, in this case zero-COVID, which had worked relatively well for China in 2020 and 2021. For decades, local governments have been major political actors in China and have known what works best under local conditions. But with tighter regulation being exercised by lower-level bureaucrats and civil servants, there is less opportunity for the input of local knowledge, increasing the risk of ineffective policies being implemented. Away from Beijing, those not employed by the state have been hit particularly hard by zero-COVID measures. The strategy has intensified economic pressures, exacerbated rising levels of youth unemployment, and tested the patience of the entire country. It is difficult to see how China’s economy can crank up again until the country reduces its internal restrictions and reconnects with the world Billions of Chinese people want to have their life return to normal without the fear of having the wrong colour – yellow or red – on their COVID health QR code or endless mandatory testing. Only a green code shows that a person is healthy and able to move around freely. Economy is suffering China is still balancing its twin aims of containing the spread of COVID and re-engineering its economy along similar lines to the rest of the world. It is difficult to see how China’s economy can crank up again until the country reduces its internal restrictions and reconnects with the world. Full Article
vi Review: The Cultural Revolution still haunts China By www.chathamhouse.org Published On :: Mon, 30 Jan 2023 13:01:21 +0000 Review: The Cultural Revolution still haunts China The World Today mhiggins.drupal 30 January 2023 Tania Branigan’s searching ‘Red Memory’ reveals the costs to Chinese society of not addressing that upheaval’s lingering injustices, writes Nathan Law. Red Memory: Living, Remembering and Forgetting China’s Cultural RevolutionTania Branigan, Faber, £20 The Cultural Revolution, a decade-long socio-political upheaval initiated by Chairman Mao Zedong in 1966, caused as many as two million deaths and reshaped China. Under the influence of Mao’s personality cult, an entire nation was mobilized to purge the ‘reactionary elements’ in society and the Chinese Communist Party through public denunciation and demolition of traditional heritages. Children turned on their parents; pupils murdered their teachers, and those who survived the summary public trials were often banished – as a young Xi Jinping himself was, living in a cave for seven years, after his father fell from favour. Impossible moral choices In her engaging and sensitive narrative account of the revolution’s upheaval and its consequences, Tania Branigan, the Guardian’s China correspondent between 2008 and 2015, speaks to some of those who survived those terrible years, considers their impossible moral choices and explores the far-reaching legacy of the revolution in present-day China. Mao urged the party to cleanse itself of its ‘class enemies’: ‘capitalists’ such as landowners and shopkeepers, but also artists, farmers and university professors. Often their family members were tainted by association and persecuted. Branigan captures the awful sense of intimate betrayal and tragedy nowhere more than in the testimony of Zhang Hongbing, a lawyer turned zealous Red Guard. What I did to my mother was worse even than to an animal Zhang Hongbing, former Red Guard Zhang denounced his mother, a hospital worker, as a ‘counter-revolutionary’ because her father owned land. She was eventually executed but not before her son struck her twice during her arrest to show his party loyalty. ‘What I did to my mother was worse even than to an animal,’ the remorseful Zhang tells Branigan. Zhang points out that his actions were far from uncommon: ‘The whole country was doing it.’ This unreconciled sense of betrayal and fear still blights China: ‘Our society is ethically hollow. If we trace these problems to their roots, we are likely to find them in the Cultural Revolution,’ one survivor is quoted as writing. Branigan encapsulates the difficulties around reconciliation and remembering in the story of Song Binbin. As a schoolgirl in 1966, she and two classmates were the first to pin up a poster attacking teachers for urging students to focus on their work instead of the revolution. Song’s classmates then beat the school vice principal Bian Zhongyun to death in the playground. The case was never properly investigated, and the death was dismissed as an accident. The pain of remembering In 2014, Song apologized publicly for the poster and expressed a sense of guilt for not intervening on Bian’s behalf. But Bian’s widower rejected the apology. Song did not speak to Branigan herself, instead allowing her friends to speak in her defence. ‘They had spoken of truth and reconciliation, but not once of justice. Every remark brought them towards closure, not accountability,’ Branigan writes. The inability to come to terms with the past pervades the book, most of whose interviewees express feelings of resentment, fear and shame about the Cultural Revolution. I sensed the same emotions when, as a boy, I talked to a neighbour in Hong Kong who was then in his 70s. He escaped from China in the late 1960s due to political and economic strains. He simply nodded and fell silent when I asked him to elaborate. The Cultural Revolution warrants no more than a few paragraphs in official textbooks As Branigan writes: ‘Most Cultural Revolution survivors had learnt to bend with the will of the time; not only to do as they were told but to imply that doing so was their own idea. It was better – safer – to stay silent or lie.’ This collective trauma is exacerbated by official unwillingness to address the past. The Cultural Revolution warrants no more than a few paragraphs in official textbooks with no mention of the suffering it unleashed. Documents of the period that might tarnish the CCP remain unavailable; any attempts to interrogate the Cultural Revolution are condemned as ‘historical nihilism’ by the party. Full Article
vi Mutation of an atypical oxirane oxyanion hole improves regioselectivity of the {alpha}/{beta}-fold epoxide hydrolase Alp1U [Enzymology] By www.jbc.org Published On :: 2020-12-11T00:06:20-08:00 Epoxide hydrolases (EHs) have been characterized and engineered as biocatalysts that convert epoxides to valuable chiral vicinal diol precursors of drugs and bioactive compounds. Nonetheless, the regioselectivity control of the epoxide ring opening by EHs remains challenging. Alp1U is an α/β-fold EH that exhibits poor regioselectivity in the epoxide hydrolysis of fluostatin C (compound 1) and produces a pair of stereoisomers. Herein, we established the absolute configuration of the two stereoisomeric products and determined the crystal structure of Alp1U. A Trp-186/Trp-187/Tyr-247 oxirane oxygen hole was identified in Alp1U that replaced the canonical Tyr/Tyr pair in α/β-EHs. Mutation of residues in the atypical oxirane oxygen hole of Alp1U improved the regioselectivity for epoxide hydrolysis on 1. The single site Y247F mutation led to highly regioselective (98%) attack at C-3 of 1, whereas the double mutation W187F/Y247F resulted in regioselective (94%) nucleophilic attack at C-2. Furthermore, single-crystal X-ray structures of the two regioselective Alp1U variants in complex with 1 were determined. These findings allowed insights into the reaction details of Alp1U and provided a new approach for engineering regioselective epoxide hydrolases. Full Article
vi The endosomal trafficking regulator LITAF controls the cardiac Nav1.5 channel via the ubiquitin ligase NEDD4-2 [Computational Biology] By www.jbc.org Published On :: 2020-12-25T00:06:30-08:00 The QT interval is a recording of cardiac electrical activity. Previous genome-wide association studies identified genetic variants that modify the QT interval upstream of LITAF (lipopolysaccharide-induced tumor necrosis factor-α factor), a protein encoding a regulator of endosomal trafficking. However, it was not clear how LITAF might impact cardiac excitation. We investigated the effect of LITAF on the voltage-gated sodium channel Nav1.5, which is critical for cardiac depolarization. We show that overexpressed LITAF resulted in a significant increase in the density of Nav1.5-generated voltage-gated sodium current INa and Nav1.5 surface protein levels in rabbit cardiomyocytes and in HEK cells stably expressing Nav1.5. Proximity ligation assays showed co-localization of endogenous LITAF and Nav1.5 in cardiomyocytes, whereas co-immunoprecipitations confirmed they are in the same complex when overexpressed in HEK cells. In vitro data suggest that LITAF interacts with the ubiquitin ligase NEDD4-2, a regulator of Nav1.5. LITAF overexpression down-regulated NEDD4-2 in cardiomyocytes and HEK cells. In HEK cells, LITAF increased ubiquitination and proteasomal degradation of co-expressed NEDD4-2 and significantly blunted the negative effect of NEDD4-2 on INa. We conclude that LITAF controls cardiac excitability by promoting degradation of NEDD4-2, which is essential for removal of surface Nav1.5. LITAF-knockout zebrafish showed increased variation in and a nonsignificant 15% prolongation of action potential duration. Computer simulations using a rabbit-cardiomyocyte model demonstrated that changes in Ca2+ and Na+ homeostasis are responsible for the surprisingly modest action potential duration shortening. These computational data thus corroborate findings from several genome-wide association studies that associated LITAF with QT interval variation. Full Article
vi In conversation with David Miliband: Finding a new approach to tackle conflict, climate and extreme poverty By www.chathamhouse.org Published On :: Thu, 15 Aug 2024 09:57:13 +0000 In conversation with David Miliband: Finding a new approach to tackle conflict, climate and extreme poverty 11 September 2024 — 5:00PM TO 5:45PM Anonymous (not verified) 15 August 2024 Chatham House and Online David Miliband discusses how the climate crisis, extreme poverty and conflict are becoming inextricably linked and how the global community must respond. Combatting the climate crisis, ending protracted conflicts, and alleviating poverty are three of the greatest priorities for international action. However, these three challenges become increasingly concentrated in a handful of countries. The subsequent feedback loop makes addressing these challenges even more complex.The International Rescue Committee’s (IRC’s) work in crisis-affected communities highlights this new geography of crisis. Just 16 countries, which are both climate-vulnerable and conflict-affected. This represents 43% of all people living in extreme poverty, 44% of all people affected by natural disasters and 79% of all people in humanitarian need. This trend towards the concentration of crisis is only deepening. In three decades, the number of conflict-affected, climate-vulnerable states has increased from 44% to more than two-thirds.Affected countries - like Sudan, Myanmar, and Syria - are also among the least supported financially. Debt burdens are siphoning away critical resources needed for adaptation and resilience. Humanitarian aid budgets are being slashed by donor governments. The private sector refuses to invest in these communities they view as too risky. And the international financial institutions meant to alleviate poverty and spur climate action are not well-designed to work with crisis-affected states or local communities. With the upcoming COP29 Summit in Azerbaijan focused on the New Collective Quantified Goal for climate finance, vulnerable communities will be watching closely whether they will get support in their fight against the worst impacts of the climate crisis.Conflict, the climate crisis, and extreme poverty are taking their toll. But how can the world best respond?Key questions to be discussed during the session include:At a time of political disruption, how does the West engage with vulnerable countries? What actions should be prioritised in providing support to such countries?Can global institutions evolve to better protect vulnerable and displaced people from conflict and climate-risk, particularly as geopolitical rivalries reduce space for cooperation?What is the UK’s role in supporting climate action in fragile states and how does this align with its agenda on the Sustainable Development Goals and extreme poverty? Full Article
vi In conversation with Martin Griffiths: How can a divided world address conflict? By www.chathamhouse.org Published On :: Mon, 16 Sep 2024 19:52:13 +0000 In conversation with Martin Griffiths: How can a divided world address conflict? 1 October 2024 — 10:00AM TO 11:00AM Anonymous (not verified) 16 September 2024 Chatham House and Online The former United Nations Under-Secretary-General describes how a weakening multilateralism system and dysfunctional political diplomacy can be revitalized by a humanitarian approach. The international community is failing to stop conflict. Despite efforts by international organisations and state actors to resolve or prevent it from breaking out, wars around the world have left millions of people suffering. Unstable governments and global insecurity are contributing to an age of poly-crisis, compounded by growing inequity and impunity.How can a divided world work better to prevent and resolve conflict and reduce the suffering of the civilians affected?Martin Griffiths has spent decades working within the United Nations system and other institutions on conflict resolution and humanitarian action, most recently as Under-Secretary General for Humanitarian Affairs and the Emergency Relief Coordinator. He worked on peace deals in Indonesia, Spain, Thailand, Myanmar, Darfur, Syria and Yemen and responded to emergencies in Ethiopia, Haiti, Afghanistan, Syria, Ukraine, Sudan, Turkiye and Gaza and elsewhere. In this discussion, he casts his expertise over the biggest challenges in the world today and assess the prospects for international cooperation on conflict resolution in the future.Key questions to be discussed include:How can a lasting peace be secured in the conflict between Israel and Palestine ?Is the world too fragmented to prevent or resolve conflicts around the world?What role can the United Nations play in today’s geopolitical environment?How can the West and Global South better engage to limit conflict ?Individual membership provides you with the complete Chatham House experience, connecting you with a unique global policy community. Find out more about membership. Full Article
vi Civilian priorities for ending the war in Sudan By www.chathamhouse.org Published On :: Tue, 08 Oct 2024 08:17:13 +0000 Civilian priorities for ending the war in Sudan 31 October 2024 — 12:30PM TO 1:30PM Anonymous (not verified) 8 October 2024 Chatham House and Online Dr Abdalla Hamdok, former prime minister of Sudan and chairperson of the Coordination of Civil Democratic Forces (Tagadum), will discuss the prospects for conflict resolution in Sudan. The intensification of fighting across Sudan demonstrates that both warring parties and their allies are continuing to pursue an outright military victory in the war, with little regard for the human cost. Diplomatic efforts, including the US-led Geneva talks in August, have produced little progress towards a ceasefire. Meanwhile, the conflict has resulted in widespread devastation, mass displacement, and an escalating hunger crisis.Civilian perspectives on ending the war, their vital efforts in providing lifesaving humanitarian assistance, and the aspiration of many Sudanese for a more inclusive and democratic Sudan, have been sidelined by the interests and actions of the belligerent parties.At this event, Dr Abdalla Hamdok will discuss options for reaching a ceasefire and seeking a peaceful political resolution to the conflict. He will also address the urgent need for an international response to what has become the world’s largest humanitarian crisis.Please note that in-person attendance for this event will be balloted. Guests looking to join in-person must ‘register interest’ in joining. Full confirmations to successful applicants will be sent on Monday 28 October at 15:00.Individual membership provides you with the complete Chatham House experience, connecting you with a unique global policy community. Find out more about membership. Full Article
vi Calpain activation mediates microgravity-induced myocardial abnormalities in mice via p38 and ERK1/2 MAPK pathways [Molecular Bases of Disease] By www.jbc.org Published On :: 2020-12-04T00:06:06-08:00 The human cardiovascular system has adapted to function optimally in Earth's 1G gravity, and microgravity conditions cause myocardial abnormalities, including atrophy and dysfunction. However, the underlying mechanisms linking microgravity and cardiac anomalies are incompletely understood. In this study, we investigated whether and how calpain activation promotes myocardial abnormalities under simulated microgravity conditions. Simulated microgravity was induced by tail suspension in mice with cardiomyocyte-specific deletion of Capns1, which disrupts activity and stability of calpain-1 and calpain-2, and their WT littermates. Tail suspension time-dependently reduced cardiomyocyte size, heart weight, and myocardial function in WT mice, and these changes were accompanied by calpain activation, NADPH oxidase activation, and oxidative stress in heart tissues. The effects of tail suspension were attenuated by deletion of Capns1. Notably, the protective effects of Capns1 deletion were associated with the prevention of phosphorylation of Ser-345 on p47phox and attenuation of ERK1/2 and p38 activation in hearts of tail-suspended mice. Using a rotary cell culture system, we simulated microgravity in cultured neonatal mouse cardiomyocytes and observed decreased total protein/DNA ratio and induced calpain activation, phosphorylation of Ser-345 on p47phox, and activation of ERK1/2 and p38, all of which were prevented by calpain inhibitor-III. Furthermore, inhibition of ERK1/2 or p38 attenuated phosphorylation of Ser-345 on p47phox in cardiomyocytes under simulated microgravity. This study demonstrates for the first time that calpain promotes NADPH oxidase activation and myocardial abnormalities under microgravity by facilitating p47phox phosphorylation via ERK1/2 and p38 pathways. Thus, calpain inhibition may be an effective therapeutic approach to reduce microgravity-induced myocardial abnormalities. Full Article
vi High affinity binding of SARS-CoV-2 spike protein enhances ACE2 carboxypeptidase activity [Molecular Bases of Disease] By www.jbc.org Published On :: 2020-12-25T00:06:31-08:00 The novel severe acute respiratory syndrome coronavirus (SARS-CoV-2) has emerged to a pandemic and caused global public health crisis. Human angiotensin-converting enzyme 2(ACE2) was identified as the entry receptor for SARS-CoV-2. As a carboxypeptidase, ACE2 cleaves many biological substrates besides angiotensin II to control vasodilatation and vascular permeability. Given the nanomolar high affinity between ACE2 and SARS-CoV-2 spike protein, we investigated how this interaction would affect the enzymatic activity of ACE2. Surprisingly, SARS-CoV-2 trimeric spike protein increased ACE2 proteolytic activity ∼3-10 fold against model peptide substrates, such as caspase-1 substrate and Bradykinin-analog. The enhancement in ACE2 enzymatic function was mediated by the binding of SARS-CoV-2 spike RBD domain. These results highlighted the potential for SARS-CoV-2 infection to enhance ACE2 activity, which may be relevant to the cardiovascular symptoms associated with COVID-19. Full Article
vi Virtual Roundtable: The Economic Implications of COVID-19 on Asia By www.chathamhouse.org Published On :: Fri, 27 Mar 2020 16:35:01 +0000 Virtual Roundtable: The Economic Implications of COVID-19 on Asia 2 April 2020 — 11:00AM TO 12:00PM Anonymous (not verified) 27 March 2020 Chatham House | 10 St James's Square | London | SW1Y 4LE The COVID-19 pandemic is likely to have a damaging economic impact on Asia, potentially the most serious since the financial crisis two decades ago. While early estimates suggest that a recession is inevitable, differing countries in Asia are generally deploying modest fiscal and monetary measures. This is true even in China, compared with the ‘whatever it takes’ approach pursued by Europe and America. How effective will these measures be in reviving growth and in easing the pain, particularly on the poor in developing countries in Asia? Is Asia witnessing a sudden but temporary halt in economic activity rather than a prolonged slowdown? At this virtual roundtable, the speakers will consider the likelihood of a recovery for trade in the region and will explore what lessons can be learned from countries like Singapore, who seem to be successfully managing the health and economic aspects of COVID-19. This event is online only. After registering, you will receive a follow-up confirmation email with details of how to join the webinar. Full Article
vi China's Evolving Economic Relations with North Africa: Before and After COVID-19 By www.chathamhouse.org Published On :: Thu, 20 Aug 2020 14:30:01 +0000 China's Evolving Economic Relations with North Africa: Before and After COVID-19 10 September 2020 — 12:00PM TO 1:30PM Anonymous (not verified) 20 August 2020 Online China’s economic presence across North Africa has grown in recent years. The global power has forged close economic relationships with Egypt and Algeria, while also continuing to develop ties with Morocco and Tunisia. Beijing, which views the region as a geostrategic intersection between Mediterranean, Middle East, and Africa, has primarily focused its efforts on developing bilateral relations, while also working within the Forum on China–Africa Cooperation (FOCAC) and the China–Arab States Cooperation Forum (CASCF). All countries of the region have agreed to participate in China’s Belt and Road initiative (BRI), which has raised concerns among Western powers. As North African countries grapple with fiscal constraints as part of the fallout from COVID-19 (and the oil price drop for hydrocarbon exporters such as Algeria), it is yet to be seen whether China’s ambitions and relations within the region will continue to develop at the same pace going forward. In this webinar, organized by Chatham House’s MENA and Asia-Pacific Programmes, experts will discuss the evolving economic relationship between China and North African states, and explore the impact of China’s pandemic diplomacy across the region. How asymmetric are economic relations between China and North African states? Which sectors are most important, and what are the prospects for China to develop the region’s digital and healthcare infrastructure? Will China’s increasing economic interests necessitate an increasing political and security engagement? Should North African states be wary of Chinese loans? What is the public opinion of China’s economic presence in North Africa? Have Chinese ‘soft power’ efforts helped to bolster economic (and political) ties? What will be the likely fallout of COVID-19 on BRI and infrastructure projects in the region? You can express your interest in attending by following this link. You will receive a Zoom confirmation email should your registration be successful. Alternatively, you can watch the event live on the MENA Programme Facebook page. Full Article
vi Interview: Nicole Hemmer By www.chathamhouse.org Published On :: Tue, 27 Sep 2022 17:38:39 +0000 Interview: Nicole Hemmer The World Today rescobales.drupal 27 September 2022 The political historian talks to Mike Higgins about how Donald Trump has transformed the US midterm elections and the Republican party’s lurch further right. Partisans: The Conservative Revolutionaries Who Remade American Politics in the 1990sNicole Hemmer, Basic Books, $18.99 In Partisans, you argue that the American political far right had been preparing the conditions for Donald Trump for 25 years and ‘the puzzle pieces snapped into place’ when he was nominated in 2016. What did you mean by that? There were changes happening in plain sight over a quarter of a century. Such as the rise of presidential candidates who had never held elected office but who had a following in conservative media and cable news more broadly. There was also a turn towards pessimism, to connections with extreme groups and to procedural extremism in the Republican Party, such as the impeachment of Bill Clinton over what most Americans agreed was a small indiscretion. All that accelerates in the 2000s and 2010s to the point where if you look back from Trump’s election, he suddenly seems eligible in a way that I don’t think he was in 2015 during his ascendancy. How did the end of the Cold War open the door for the hard right in the early 1990s? The Cold War is so important to making sense of conservative politics in the United States because it sat at the core of American conservatism for 50 years. Opposition to Soviet communism held together the conservative coalition. It brought together religious conservatives who talked about the atheistic Soviet Union with the libertarians who were fearful of a big state. The Cold War forced conservatives to talk in a language of freedom and democracy The Cold War forced conservatives to talk in a language of freedom and democracy because that was the way that the US was different from the Soviet Union. Ronald Reagan, in particular, was a master of this. It had real implications for domestic policy. Reagan embraced free trade and talked about immigration and diversity as things that were great for America. And then the Cold War ends, and you have politicians like Pat Buchanan [a former White House Communications Director] who had been beating the Reagan line for years, coming out and saying: ‘You know what? Immigration is bad and immigrants are bad. They are harmful for the United States. Free Trade is bad. We need to have more protectionist economy and build Fortress America. And, by the way, democracy might not actually be the best form of government for our country. The Marine Corps and IBM are better run than the federal government, and those are autocratic governed institutions.’ It allowed a resurgence of a right-wing politics that the US hadn’t seen since the 1930s and 1940s. It would become a powerful political movement within conservatism that we ultimately see taking over the Republican Party by the 2010s. What was it that allowed far-right figures such as Rush Limbaugh to take advantage of the transformation of the media in the 1990s? Part of what they saw in it was interactivity. We tend to associate that with the internet and with the rise of social media, but call-in national radio and cable TV gave people an opportunity to have their voices heard. The most popular TV show on CNN was Larry King Live, a call-in show. That interactivity fed into this idea that a frustrated populace suddenly had a voice, and it was easy to play on that sense of frustration. Also, the right was innovative because they had been focused on alternative media for decades. The right was innovative because they had been focused on alternative media for decades So, as you get new formats in the 1990s like political talk radio and cable news, conservatives were already in that space looking for ways to get their message across. Also, journalistic objectivity in the 1990s became getting a voice from the right and a voice from the left, which opened the door for a new generation of conservative pundits such as TV hosts Laura Ingraham and Ann Coulter. You have these incentives drawing the right into this new media and all of these conservatives in the base who are looking for right-wing voices. There are hearings into the January 6, 2021, Capitol invasion and an FBI investigation into the alleged presence of confidential papers at Trump’s residence Mar-a-Lago. Are we about to witness the insurgent far right within the Republican Party being brought to account legally? There has been more accountability than I anticipated at the beginning of the Trump presidency. Some innovative legal techniques are being used successfully, such as sedition and conspiracy charges against some of the Capitol rioters. Steve Bannon, one of Trump’s chief advisers in the 2016 campaign, has been charged with money laundering, conspiracy and fraud during the Trump presidency. Will that accountability lead to a fundamental transformation of right-wing politics in the US? I wouldn’t bet on that. How is the radicalism of the Republican party shaping the upcoming mid-term elections? The real radicalism in the Republican Party now is its willingness to use both procedural mechanisms but also mob violence to get the electoral outcomes that it wants – something that we saw with the insurrection on January 6, 2021. If Republicans at the midterms vote in candidates prepared to overturn election results they dislike, that’s a challenge to American democracy That makes the mid-terms an existential election if Republicans are able to vote in candidates who are running on a platform of throwing out election results if Republicans don’t win. That is a real challenge to the future of American democracy. As long as the political system is organized around one party that respects the rules of democracy and one party that fights against them, each election is going to be existential. It will make mid-term elections have the weight that the 2016 and 2020 presidential elections had. Did the far right misunderstand the electorate when it comes to abortion, considering the strong reaction to the Dobbs ruling? I think that is exactly right, and it’s fascinating. A major turn happens in American politics between the 1980s and the 1990s, especially on the right. Ronald Reagan built these broad coalitions. He was winning landslide elections, and building this ‘big tent’ party that would bring in people who didn’t identify as Republicans or conservatives. By the time you get to the 1990s, you have this idea of the Rino – politicians who are ‘Republican in name only’. You had to be purer and purer when it came to your right-wing politics. And the Republican Party grew a lot more unpopular. It has lost elections because of the extremism of its candidates, but it has still been able to win democratic elections without majorities, something we saw in 2000 and 2016. The outcome of it all is exactly what you are seeing right now, that in many ways the conservative movement has got something it wanted for half a century, which is the overturning of Roe v Wade – something that energized its space for a very long time. Now that the dog has caught the fire truck, it is looking around and saying: ‘Oh, people do not like this.’ August’s referendum in Kansas that upheld the right to abortion mobilized lots of voters August’s referendum in Kansas that upheld the right to abortion mobilized lots of voters who normally wouldn’t have come out for an off-year election. As you get more stories of 10-year-old rape victims who have to go to a different state to get an abortion, or stories of women who have high-risk pregnancies not able to get medical care because of these new extremist laws, that really does mobilize a population who understand what is at stake. It is not just their access to abortion, but to reproductive healthcare more broadly. Not everywhere, but in some places that is going to change the dynamics of these mid-term races. Full Article
vi Divided US support shows time is not on Ukraine’s side By www.chathamhouse.org Published On :: Fri, 17 Feb 2023 12:29:08 +0000 Divided US support shows time is not on Ukraine’s side Expert comment LJefferson 17 February 2023 Growing public opinion evidence and uncertainty about the future of the war suggests that continued American support for aiding Ukraine should not be assumed. One year into Russia’s war on Ukraine, fears that American support for Kyiv would rapidly wane have proven demonstrably wrong. Western financial and military backing has been robust thanks to allied unity and an unexpectedly mild winter. But, as financial analysts constantly remind us, past performance is no guarantee of future results. People like to back winners. If the anticipated Russian spring offensive looks successful or the counterpart Ukrainian offensive is uninspiring, expect louder US voices calling for a negotiated settlement. The warning signs are already here. American officials privately express growing apprehension that there will be an early resolution of the conflict. As one White House official recently observed to me, by the end of the year the war could well be about where it is today. And a plurality of Americans intuitively grasp this: 46 per cent believe neither Russia nor Ukraine currently has the advantage in the conflict. Momentum matters In public opinion, perception of momentum matters. Americans’ support for the Vietnam War waned as the conflict persisted, falling from six-in-ten Americans in 1965 to four-in-ten in 1973. Similarly, backing for the Iraq war fell from more than seven-in-ten in 2003 to barely four-in-ten in 2008. And with Afghanistan, as the war dragged on, support for US involvement fell from more than nine-in-ten in 2002 to less than five-in-ten in 2021. Notably, once the American public turned on these wars, support never returned. Of course, Americans were fighting and dying in those wars, which is not the case in the Ukraine conflict. But initially the Vietnam, Iraq, and Afghanistan war support was buoyed by the belief that continued US engagement was justified, otherwise American sons and daughters had died in vain. With no American lives at stake in Ukraine, only financial and military resources, there is a growing wariness of throwing good money after bad. In the last year, the share of Americans who say the United States is doing too much for Ukraine has nearly quadrupled, from seven to 26 per cent. And the portion that believe Washington has not done enough has halved, from 49 per cent to 17 per cent. Sentiment about Ukraine support has become increasingly partisan. In March 2022, nine per cent of Republicans and five per cent of Democrats said the US was doing too much for Ukraine. By January 2023, 40 per cent of Republicans but just 15 per cent of Democrats complained Washington was doing too much. In the last year, the share of Americans who say the United States is doing too much for Ukraine has nearly quadrupled, from 7% to 26%. This erosion of Americans’ support for Ukraine does not bode well for the future. Less than half (48 per cent) of the public in November, compared to 58 per cent in July, believed Washington should support Ukraine for as long as it takes, even if it means American households have to pay higher gas and food prices as a consequence. A similar share, 47 per cent – up from 38 per cent in July – said the United States should urge Ukraine to settle for peace as soon as possible so the costs aren’t so great for American households, even if that means Ukraine will lose some territory. A partisan divide The partisan divide over Ukraine is largely driven by Republican political rhetoric during and after the 2022 midterm elections. Current Republican Speaker of the House Kevin McCarthy observed last October: ‘I think people are going to be sitting in a recession and they’re not going to write a blank cheque to Ukraine.’ More recently, in the wake of Ukrainian president Zelenskyy’s December speech to Congress, Florida Republican Representative Matt Gaetz, whose vote was pivotal in making McCarthy Speaker, tweeted: ‘Hemorrhaging billions in taxpayer dollars for Ukraine while our country is in crisis is the definition of America last.’ In January, newly-elected Ohio Republican Senator J.D. Vance told a Cleveland radio station that it was ‘ultimately not in our national security interest’ to send M1 Abrams tanks to Ukraine, despite the fact that they will be built by his constituents in Ohio. In addition, ten Republican members of the House of Representatives have introduced legislation asserting ‘that the United States must end its military and financial aid to Ukraine, and urges all combatants to reach a peace agreement.’ And this month former President Donald Trump said: ‘That war has to stop, and it has to stop now, and it’s easy to do’ and it ‘can be negotiated within 24 hours’. Why worry about continued support for the war if it’s about to be over? The road to 2024 With the 2024 US presidential election already revving up, Americans’ appetite for continued backing for Ukraine may hinge on how voters judge the Biden administration’s handling of the conflict. Democrats are more than twice as likely as Republicans (61 per cent versus 27 per cent) to approve of the Biden administration’s response to the Russia invasion, suggesting Ukraine will be yet another partisan talking point as the campaign heats up. Notably, men are much more likely than women to approve of Biden’s efforts, as are older Americans compared with younger Americans. Full Article