ed Youth injured in accident in Idukki By www.thehindu.com Published On :: Wed, 13 Nov 2024 21:02:46 +0530 Full Article Kerala
ed Food prices rising due to failed policies of Modi govt., says Congress By www.thehindu.com Published On :: Wed, 13 Nov 2024 21:03:46 +0530 Tomatoes, onions, and potatoes disappearing from common man’s plate, says Jairam Ramesh Full Article India
ed New rest norms for pilots will reduce their salary, Air India tells DGCA By www.thehindu.com Published On :: Wed, 13 Nov 2024 21:12:20 +0530 Meeting held as part of mediation ordered by Delhi High Court between pilots and airlines Full Article India
ed Children’s Day: public meet, rally led by girls to be held in Thiruvananthapuram By www.thehindu.com Published On :: Wed, 13 Nov 2024 21:41:04 +0530 25,000 students from 200 schools will be part of the rally Full Article Kerala
ed Try to stand on your own legs, Supreme Court tells NCP led by Ajit Pawar to stop using Sharad Pawar’s pictures, videos By www.thehindu.com Published On :: Wed, 13 Nov 2024 21:49:46 +0530 The Bench asked the Ajit Pawar camp to circulate an online message among its leaders, party workers and representatives against using the pictures or video/audio clips of Sharad Pawar, whether old or new Full Article India
ed Hope SC will hold accountable those who reduced homes to rubble: Mehdi By www.thehindu.com Published On :: Thu, 14 Nov 2024 07:44:10 +0530 “I hope that the court will hold accountable those who have committed these crimes, and have reduced homes to rubble.” Full Article India
ed ED arrests four, including two Bangladeshi nationals, in human trafficking case By www.thehindu.com Published On :: Thu, 14 Nov 2024 07:52:22 +0530 Full Article India
ed Indian households accumulated USD 9.7 trillion in wealth over last ten years: Morgan Stanley By www.newkerala.com Published On :: Wed, 13 Nov 2024 17:34:02 +0530 Full Article
ed 'Any relief on bank guarantee will be provided across the sector': Scindia on Vodafone Idea request for waiver of bank guarantees for spectrum By www.newkerala.com Published On :: Wed, 13 Nov 2024 17:36:01 +0530 Full Article
ed India IT spending to reach USD 160 billion in 2025 fueled by application and infrastructure software market growth: Gartner By www.newkerala.com Published On :: Wed, 13 Nov 2024 17:38:01 +0530 Full Article
ed Google.org awards USD 1 mn grant to Karya to boost ai-based economic opportunities for low-income communities By www.newkerala.com Published On :: Wed, 13 Nov 2024 17:40:02 +0530 Full Article
ed Integrated manufacturing cluster to be developed in Bihar's Gaya By www.newkerala.com Published On :: Wed, 13 Nov 2024 17:56:03 +0530 Full Article
ed An Efficient All-Visible Light-Activated Photoswitches Based on Diarylethenes and CdS Quantum Dots By pubs.rsc.org Published On :: Chem. Sci., 2024, Accepted ManuscriptDOI: 10.1039/D4SC06110A, Edge Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Kezhou Chen, Jiayi Liu, Joakim Andréasson, Bo Albinsson, Tiegen Liu, Lili HouAll-visible light-activated diarylethene (DAE) photoswitches are highly attractive for applications in smart photoresponsive materials. Photocyclization of DAE via the low-lying excited triplet state through triplet energy transfer (TET) from a...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ed Phase transition induced hydrogen activation for enhanced furfural reductive amination over CoCu bimetallic catalyst By pubs.rsc.org Published On :: Chem. Sci., 2024, Accepted ManuscriptDOI: 10.1039/D4SC05885B, Edge Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Yilin Wei, Zixu Ma, Beibei Liu, Jialin Yang, Dan Wu, Yongsheng Zhang, Yuexing Zhang, Charles Chunbao Xu, Renfeng NieThe synthesis of primary amines from renewable biomass and its derivatives through reductive amination has garnered significant attention. How to construct efficient non-noble-metal catalysts that enable low-temperature catalysis still remains...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ed TcESTIME: predicting high-temperature hydrogen-based superconductors By pubs.rsc.org Published On :: Chem. Sci., 2024, Accepted ManuscriptDOI: 10.1039/D4SC04465G, Edge Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Trinidad Novoa, Matías E. di Mauro, Diego Inostroza, Kaoutar El Haloui, Nicolas Sisourat, Yvon Maday, Julia Contreras-GarcíaSuperconductivity can be considered among the most exciting discoveries in material science of the XXth century. However, the hard conditions for the synthesis and the difficult characterization, make the statement...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ed Gaining the Molecular Design Principles for Efficient Diarylethene Photoacid and Photohydride Generators Based on Photochemical Reaction Mechanism By pubs.rsc.org Published On :: Chem. Sci., 2024, Accepted ManuscriptDOI: 10.1039/D4SC06202G, Edge Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Yifan Su, Dexin Zheng, Lingfeng Ge, Le Yu, David Lee Phillips, Jiani Ma, Yu FangAbstract: Photoacid generators (PAGs) and photohydride generators (PHGs) are specific photolabile protecting groups that release acid and hydride, respectively. Over the past decade, great efforts have been devoted to developing...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ed Synthesis of highly condensed phospholes by Lewis acid-assisted dehydrogenative Mallory reaction under visible light irradiation By pubs.rsc.org Published On :: Chem. Sci., 2024, Accepted ManuscriptDOI: 10.1039/D4SC05657D, Edge Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Ikki Kamiyoshi, Yuki Kojima, Shibo Xu, Kosuke Yasui, Yuji Nishii, Koji HiranoA photo-promoted oxidative cyclization, that is, Mallory reaction of 2,3-diarylbenzophopholes has been developed. With an assistance of Bi(OTf)3 Lewis acid, the reaction proceeds smoothly under visible light irradiation even without...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ed $19 mn Loss & Damage funding pledged by Sweden at COP29, bringing total pledged funding to $720 mn By www.newkerala.com Published On :: Wed, 13 Nov 2024 16:12:02 +0530 Full Article
ed Assam: Army celebrates 'National Education Day' with students in Tinsukia By www.newkerala.com Published On :: Wed, 13 Nov 2024 19:08:01 +0530 Full Article
ed UP: Devotees celebrate 'Tulsi Vivah' at Balua Ghat in Prayagraj, marking sacred union of Lord Vishnu, Vrinda By www.newkerala.com Published On :: Wed, 13 Nov 2024 19:10:02 +0530 Full Article
ed There will be census in country but not based on caste: Union Minister Shobha Karandlaje By www.newkerala.com Published On :: Wed, 13 Nov 2024 19:18:02 +0530 Full Article
ed Union Education Minister Dharmendra Pradhan urges states to support exam reforms for zero-error entrance test By www.newkerala.com Published On :: Wed, 13 Nov 2024 19:22:01 +0530 Full Article
ed Akashteer: Transforming India's air defence with cutting-edge technology By www.newkerala.com Published On :: Wed, 13 Nov 2024 19:26:02 +0530 Full Article
ed Union Jal Shakti Minister CR Paatil chairs 13th high-powered review meeting of Brahmaputra Board By www.newkerala.com Published On :: Wed, 13 Nov 2024 19:34:02 +0530 Full Article
ed AI and hi-tech technologies will be used in CCTV arrangements: UP DGP Prashant Kumar on Mahakumbh 2025 preparations By www.newkerala.com Published On :: Wed, 13 Nov 2024 19:40:02 +0530 Full Article
ed All cases related to loan fraud at Perumbavoor Urban Cooperative Society to be handed over to Crime Branch By www.thehindu.com Published On :: Wed, 13 Nov 2024 18:46:46 +0530 Police say 29 cases have been registered. Probe by district joint registrar of Cooperative department finds 26 persons, mostly members of previous director boards, accountable for irregularities to the tune of ₹33.33 crore Full Article Kerala
ed French lower house rejects massively amended 2025 budget By www.thehindu.com Published On :: Wed, 13 Nov 2024 09:53:03 +0530 Prime Minister Michel Barnier's minority government now has a largely free hand in submitting a cleaned-up text to the Senate upper house Full Article World
ed Uzbekistan to make media, songs and films pass 'moral test' By www.thehindu.com Published On :: Wed, 13 Nov 2024 11:45:22 +0530 President Shavkat Mirziyoyev has introduced some reforms since coming to power after the 2016 death of dictator Islam Karimov, but rights groups say the country remains deeply authoritarian Full Article World
ed ‘Anti-war’ comedy play riles Bulgarian nationalists By www.thehindu.com Published On :: Wed, 13 Nov 2024 11:50:04 +0530 Last week’s premiere of Arms and the Man by renowned Irish-born playwright George Bernard Shaw sparked raucous protests by nationalist groups Full Article World
ed Xi leaves China for APEC meeting in Peru: state media By www.thehindu.com Published On :: Wed, 13 Nov 2024 12:55:46 +0530 Chinese leader Xi Jinping travels to Peru for APEC summit amid trade tensions with U.S., inaugurates Chinese-funded port Full Article News
ed Iran executes in public a serial rapist convicted in dozens of cases By www.thehindu.com Published On :: Wed, 13 Nov 2024 14:43:02 +0530 Iran’s state media say authorities have executed in public a man convicted of raping dozens of women over two decades Full Article World
ed Lebanon media claims Israeli strike hit apartment south of Beirut By www.thehindu.com Published On :: Wed, 13 Nov 2024 15:10:43 +0530 Israeli warplanes launched a strike at dawn targeting a residential apartment in a building in the Dawhet Full Article World
ed France’s bullfighters see red over bill to ban under-16s By www.thehindu.com Published On :: Wed, 13 Nov 2024 16:10:52 +0530 Although public opinion favours outlawing bullfighting in France, a bid to ban the practice failed in 2022 Full Article World
ed Senior Russian naval officer killed in car bombing claimed by Kyiv By www.thehindu.com Published On :: Wed, 13 Nov 2024 21:28:48 +0530 Russia's state Investigative Committee said in a statement that an improvised explosive device had detonated in an act of terrorism, killing a serviceman whom it did not identify Full Article World
ed In vitro identification of oridonin hybrids as potential anti-TNBC agents inducing cell cycle arrest and apoptosis by regulation of p21, γH2AX and cleaved PARP By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3674-3694DOI: 10.1039/D4MD00580E, Research ArticleJinhua Ning, Nini Zhan, Zhanpan Wu, Yuzhe Li, Die Zhang, Yadian Shi, Yingxun Zhou, Chuan-Huizi Chen, Wenbin JinOridonin analogue 11a showed significant antitumor efficacy in vitro via cell cycle arrest and apoptosis by regulation of p21, γH2AX and cleaved PARP accumulation, meanwhile, displayed much more stable than oridonin in human plasma.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ed New ATP-competitive inhibitors of E. coli GyrB obtained from the mapping of the hydrophobic floor at the binding site: synthesis and biological evaluation By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3759-3777DOI: 10.1039/D4MD00498A, Research ArticleLucas Gutierrez, Peter Peršolja, Rodrigo Tosso, Nace Zidar, Danijel Kikelj, Ricardo D. EnrizA diagram of the active site of E. coli gyrase B, highlighting the hydrophobic subsite, including key residues relevant to ligand binding.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ed Discovery of hybrid Glypromate conjugates with neuroprotective activity against paraquat-induced toxicity By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3711-3727DOI: 10.1039/D4MD00584H, Research ArticleSara C. Silva-Reis, Vera M. Costa, Daniela Correia da Silva, David M. Pereira, Xavier Cruz Correia, Xerardo García-Mera, José E. Rodríguez-Borges, Ivo E. Sampaio-DiasA series of bicyclic-based Glypromate conjugates with reduction of protein aggregation elicited by Aβ25–35 and neuroprotective activity against paraquat-induced toxicity is reported, paving the way for the discovery of novel neurotherapeutics.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ed Stachydrine, a pyrrole alkaloid with promising therapeutic potential against metabolic syndrome and associated organ dysfunction By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3652-3673DOI: 10.1039/D4MD00425F, Review ArticleSemim Akhtar Ahmed, Prasenjit Manna, Jagat Chandra BorahMetabolic syndrome is a multifaceted condition marked by interconnected risk factors, significantly increasing the risk of serious diseases like cardiovascular disease, type 2 diabetes, and stroke.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ed Pyridinyl 4-(2-oxoalkylimidazolidin-1-yl)benzenesulfonates and their hydrochloride salts as novel water soluble antimitotic prodrugs bioactivated by cytochrome P450 1A1 in breast cancer cells By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3728-3745DOI: 10.1039/D4MD00476K, Research ArticleVincent Ouellette, Chahrazed Bouzriba, Atziri Corin Chavez Alvarez, Quentin Bruxelles, Geneviève Hamel-Côté, Sébastien FortinNew water soluble antimitotic CYP1A1-activated prodrugs named PYRAIB-SOs and their hydrochlorides targeting breast cancers.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ed Prediction of synergistic gemcitabine-based combination treatment through a novel tumor stemness biomarker NANOG in pancreatic cancer By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3853-3861DOI: 10.1039/D4MD00165F, Research ArticleJiongjia Cheng, Ting Zhu, Shaoxian Liu, Jiayu Zhou, Xiaofeng Wang, Guangxiang LiuThe synergistic effect observed in gemcitabine-based combination therapies targeting pancreatic cancer stem cells was correlated with the inhibiting effect on the expression of stemness-related gene NANOG.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ed Evaluating the therapeutic potential of genetically engineered probiotic Zbiotics (ZB183) for non-alcoholic steatohepatitis (NASH) management via modulation of the cGAS-STING pathway By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3817-3836DOI: 10.1039/D4MD00477A, Research ArticleMaha Saad, Walaa Ibrahim, Amany Helmy Hasanin, Aya Magdy Elyamany, Marwa MatboliZBiotics administration in the NASH model downregulated the RNA panel (MAPK3, EDN1, TNF, miR-6888-5p, lncRNA RABGAP1L-DT-206), restored intestinal barrier integrity, reduced hepatic inflammation, and improved lipid profiles and liver enzymes.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ed Hydrophobic CPP/HDO conjugates: a new frontier in oligonucleotide-warheaded PROTAC delivery By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3695-3703DOI: 10.1039/D4MD00546E, Research ArticleMiyako Naganuma, Nobumichi Ohoka, Motoharu Hirano, Daishi Watanabe, Genichiro Tsuji, Takao Inoue, Yosuke DemizuA novel hydrophobic cell-penetrating peptide (CPP) and heteroduplex oligonucleotide (HDO)-conjugated PROTAC, CPP/HDO-PROTAC, was designed to enhance its intracellular delivery and degradation efficiency.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ed Anticancer potential of copper(I) complexes based on isopropyl ester derivatives of bis(pyrazol-1-yl)acetate ligands By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4MD00610K, Research Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Maura Pellei, Carlo Santini, Miriam Caviglia, Jo' Del Gobbo, Chiara Battocchio, Carlo Meneghini, Simone Amatori, Chiara Donati, Eleonora Zampieri, Valentina Gandin, Cristina MarzanoIn this paper, the isopropyl ester derivatives LOiPr and L2OiPr of bis(pyrazol-1-yl)acetic acid and bis(3,5-dimethyl-pyrazol-1-yl)acetic acid were used as chelators for the preparation of the new Cu(I) phosphane complexes 1-4....The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ed Advances in Detecting Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) Using Molecular Receptors and Nanostructured Assemblies By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4MD00661E, Review ArticleAvijit Kumar DasThe detection and quantification of non-steroidal anti-inflammatory drugs (NSAIDs) are crucial due to their widespread use and potential impact on human health and the environment. This review provides a comprehensive...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ed IIT Madras to conduct two-day summit on extended reality By www.thehindu.com Published On :: Wed, 13 Nov 2024 13:19:23 +0530 The aim is to develop academic partnership programmes to boost research in XR or extended reality Full Article Chennai
ed Tamil Nadu CM Stalin to launch Phase II of nutritional intervention programme for malnourished children, mothers By www.thehindu.com Published On :: Wed, 13 Nov 2024 17:23:48 +0530 Mothers of over 76,700 babies in the age group of zero to six months, identified as malnourished, would be covered under Phase II of the programme Full Article Tamil Nadu
ed T.N. govt. to take a call on verifying criminal antecedents before appointing schoolteachers By www.thehindu.com Published On :: Wed, 13 Nov 2024 18:15:58 +0530 It also assures Madras High Court of putting in place an effective complaint redressal mechanism in the interest of school students Full Article Tamil Nadu
ed Southern Railway refuses to share inquiry report of Perumon train tragedy By www.thehindu.com Published On :: Wed, 13 Nov 2024 20:15:33 +0530 105 people had died in after several coaches of the Island Express fell into the Ashtamudi Lake in 1988 Full Article Tamil Nadu
ed Four Swedish companies, including IKEA, looking to set up base in Tamil Nadu: Swedish Ambassador to India By www.thehindu.com Published On :: Wed, 13 Nov 2024 20:56:01 +0530 There are 70 Swedish companies in Tamil Nadu, employing about 25,000 people. But we want to do more, says Jan Thesleff Full Article Tamil Nadu
ed DUSU election results to be announced on November 21 By www.thehindu.com Published On :: Wed, 13 Nov 2024 13:18:26 +0530 The counting of votes for both the central panel and college representatives will begin at 8:30 a.m. on November 21 at the DU Conference Centre Full Article Delhi