es COVID-19 outcomes in patients with hematologic disease By feeds.nature.com Published On :: 2020-05-06 Full Article
es Rituximab for desensitization during HLA-mismatched stem cell transplantation in patients with a positive donor-specific anti-HLA antibody By feeds.nature.com Published On :: 2020-05-08 Full Article
es NT5DC2 promotes tumor cell proliferation by stabilizing EGFR in hepatocellular carcinoma By feeds.nature.com Published On :: 2020-05-07 Full Article
es Irradiation induces cancer lung metastasis through activation of the cGAS–STING–CCL5 pathway in mesenchymal stromal cells By feeds.nature.com Published On :: 2020-05-07 Full Article
es Differential effectiveness of tyrosine kinase inhibitors in 2D/3D culture according to cell differentiation, p53 status and mitochondrial respiration in liver cancer cells By feeds.nature.com Published On :: 2020-05-07 Full Article
es The HMGB1-RAGE axis modulates the growth of autophagy-deficient hepatic tumors By feeds.nature.com Published On :: 2020-05-07 Full Article
es QKI deficiency leads to osteoporosis by promoting RANKL-induced osteoclastogenesis and disrupting bone metabolism By feeds.nature.com Published On :: 2020-05-07 Full Article
es WTAP and BIRC3 are involved in the posttranscriptional mechanisms that impact on the expression and activity of the human lactonase PON2 By feeds.nature.com Published On :: 2020-05-07 Full Article
es LncRNA <i>SNORD3A</i> specifically sensitizes breast cancer cells to 5-FU by sponging miR-185-5p to enhance UMPS expression By feeds.nature.com Published On :: 2020-05-07 Full Article
es NF-kappa B interacting long noncoding RNA enhances the Warburg effect and angiogenesis and is associated with decreased survival of patients with gliomas By feeds.nature.com Published On :: 2020-05-07 Full Article
es Chromosome 11 open reading frame 30 (C11orf30), calpain small subunit 1 (CAPNS1; CAPN4), signal transducer and activator of transcription 6 (STAT6) and ankyrin repeat domain 27 (ANKRD27) as diagnostic markers for eosinophilic esophagitis (EoE) By feeds.nature.com Published On :: 2014-12-18 Genomewide association studies identified four genes that could serve as diagnostic markers and/or therapeutic targets for EoE. Full Article
es Extending therapeutic protein half-lives via fusion to affibodies with pH-dependent binding to neonatal Fc receptor By feeds.nature.com Published On :: 2014-12-18 Fusing therapeutic proteins to affibodies with pH-dependent binding to neonatal Fc receptor could improve the proteins' half-lives. Full Article
es Nanomolar-scale, high throughput chemical synthesis of drug-like molecules By feeds.nature.com Published On :: 2014-12-18 A high throughput, miniaturized chemical synthesis platform could enable rapid discovery of lead compounds. Full Article
es Dermatophagoides pteronyssinus peptidase 1 (DERP1) By feeds.nature.com Published On :: 2014-12-18 In vitro and rat studies suggest inhibiting the enzymatic activity of house dust mite (HDM) allergens could help treat allergic asthma. Full Article
es Angiopoietin 2 (ANG2; ANGPT2); placental growth factor (PGF; PlGF); tissue inhibitor of metalloproteinases 3 (TIMP3) By feeds.nature.com Published On :: 2014-12-18 Mouse studies suggest inhibiting PGF could help treat hypertension. Full Article
es Estrogen receptor; LYN kinase (LYN); phosphoinositide 3-kinase (PI3K) By feeds.nature.com Published On :: 2014-12-18 Studies in mice and human samples suggest inhibiting LYN could help treat estrogen receptor–positive breast cancers resistant to anti-estrogen therapy. Full Article
es Resurrecting a magic bullet By feeds.nature.com Published On :: 2014-12-18 Heidelberg Pharma has resuscitated a long-dead ADC toxin with updated conjugation techniques, and its partner Roche has thrown the company a lifeline that could help validate the platform. Full Article
es Neutralizing the negatives of RNAi By feeds.nature.com Published On :: 2014-12-18 The siRNN technology that Solstice licensed from UCSD could take RNAi-based therapies to tissues outside the liver and expand their use to a host of new diseases. Full Article
es Pac1/LIS1 stabilizes an uninhibited conformation of dynein to coordinate its localization and activity By feeds.nature.com Published On :: 2020-04-27 Full Article
es Tissue-resident ductal macrophages survey the mammary epithelium and facilitate tissue remodelling By feeds.nature.com Published On :: 2020-04-27 Full Article
es Myeloid PTEN promotes chemotherapy-induced NLRP3-inflammasome activation and antitumour immunity By feeds.nature.com Published On :: 2020-05-04 Full Article
es In vitro capture and characterization of embryonic rosette-stage pluripotency between naive and primed states By feeds.nature.com Published On :: 2020-05-04 Full Article
es FBP1 loss disrupts liver metabolism and promotes tumorigenesis through a hepatic stellate cell senescence secretome By feeds.nature.com Published On :: 2020-05-04 Full Article
es MicroRNA binding site polymorphism in inflammatory genes associated with colorectal cancer: literature review and bioinformatics analysis By feeds.nature.com Published On :: 2020-03-23 Full Article
es In vivo antitumor activity by dual stromal and tumor-targeted oncolytic measles viruses By feeds.nature.com Published On :: 2020-03-31 Full Article
es Oncolytic adenovirus encoding LIGHT (TNFSF14) inhibits tumor growth via activating anti-tumor immune responses in 4T1 mouse mammary tumor model in immune competent syngeneic mice By feeds.nature.com Published On :: 2020-04-20 Full Article
es TMB: a promising immune-response biomarker, and potential spearhead in advancing targeted therapy trials By feeds.nature.com Published On :: 2020-04-28 Full Article
es UNC5B mediates G2/M phase arrest of bladder cancer cells by binding to CDC14A and P53 By feeds.nature.com Published On :: 2020-05-06 Full Article
es High-purity orbital angular momentum states from a visible metasurface laser By feeds.nature.com Published On :: 2020-04-27 Full Article
es Engineering nanomedicines through boosting immunogenic cell death for improved cancer immunotherapy By feeds.nature.com Published On :: 2020-04-21 Full Article
es Nintedanib inhibits keloid fibroblast functions by blocking the phosphorylation of multiple kinases and enhancing receptor internalization By feeds.nature.com Published On :: 2020-04-23 Full Article
es Diabetes downregulates peptide transporter 1 in the rat jejunum: possible involvement of cholate-induced FXR activation By feeds.nature.com Published On :: 2020-04-27 Full Article
es An in vitro Förster resonance energy transfer-based high-throughput screening assay identifies inhibitors of SUMOylation E2 Ubc9 By feeds.nature.com Published On :: 2020-04-27 Full Article
es Compound LM9, a novel MyD88 inhibitor, efficiently mitigates inflammatory responses and fibrosis in obesity-induced cardiomyopathy By feeds.nature.com Published On :: 2020-04-27 Full Article
es Nanomedicines based on nanoscale metal-organic frameworks for cancer immunotherapy By feeds.nature.com Published On :: 2020-04-30 Full Article
es Head-to-head trials in inflammatory bowel disease: past, present and future By feeds.nature.com Published On :: 2020-04-17 Full Article
es Microbiota and colorectal cancer: colibactin makes its mark By feeds.nature.com Published On :: 2020-04-21 Full Article
es Colons or semi-colons: punctuating the regional variation of intestinal microbial–immune interactions By feeds.nature.com Published On :: 2020-04-22 Full Article
es Inducing senescence sensitizes pancreatic tumours to therapies By feeds.nature.com Published On :: 2020-04-28 Full Article
es Universal screening for hepatitis C virus infection should be linked to universal treatment access By feeds.nature.com Published On :: 2020-04-29 Full Article
es Author Correction: Management of IBD during the COVID-19 outbreak: resetting clinical priorities By feeds.nature.com Published On :: 2020-05-06 Full Article
es Effects of acute and repeated treatment with methocinnamox, a mu opioid receptor antagonist, on fentanyl self-administration in rhesus monkeys By feeds.nature.com Published On :: 2020-05-06 Full Article
es A novel multidimensional reinforcement task in mice elucidates sex-specific behavioral strategies By feeds.nature.com Published On :: 2020-05-06 Full Article
es Correction: Ketamine metabolites, clinical response, and gamma power in a randomized, placebo-controlled, crossover trial for treatment-resistant major depression By feeds.nature.com Published On :: 2020-05-06 Full Article
es Nesfatin-1 puts the brakes on reward-based feeding By feeds.nature.com Published On :: 2020-05-06 Full Article
es Evaluating the impact of trauma and PTSD on epigenetic prediction of lifespan and neural integrity By feeds.nature.com Published On :: 2020-05-07 Full Article
es Obesity affects skeletal muscle ketone oxidation By feeds.nature.com Published On :: 2020-04-20 Full Article