CBC Sports sat down with Hockey Hall of Famer Mats Sundin, showing him video of some of the biggest moments of his career.

Hired in July by the Seattle Kraken as an assistant coach after two seasons with their AHL affiliate, Jessica Campbell is starting to get to know the team, schedule demands and managing "the vigorous push through it all." It's also about managing the attention as a trailblazer.

Nine games into the Washington Capitals' season, Alex Ovechkin is scoring at a rate that would put him past Wayne Gretzky as soon as this spring.

The records just keep falling for the Jets under new head coach Scott Arniel.

U.S. president-elect Donald Trump spoke with Russian President Vladimir Putin and advised him not to escalate the Ukraine war, a source familiar with the conversation said, but the Kremlin denied the two had spoken.

Italian police have uncovered a large-scale pan-European forgery network making and selling fake artworks attributed to some of the biggest names in modern and contemporary art including Banksy, Pablo Picasso and Andy Warhol.

An Israeli airstrike killed seven people late Monday at a café near the southern Gaza city of Khan Younis, Palestinian medics said, bringing the death toll from Israeli strikes since Sunday night to at least 37.

Sgt. Harman Dhaliwal, who is from Calgary, says he's proud to be a part of the growing exhibit that highlights the relationship between the Sikh faith and military service.

The provincial government is seeking contractors to restore hundreds of kilometres of land where fireguards were created during the 2023 wildfire season.

The Calgary-based team beat Hamilton Forge FC in a 2-1 nail-biter at home on Saturday, in front of a sold-out crowd of over 7,000 fans at Spruce Meadows.

After Canada Post workers gave a 72-hour notice to strike early Tuesday, some Calgary business owners are worried about what this means for holiday season sales. 

CME Group, the world's leading derivatives marketplace, today announced that open interest in its global benchmark Henry Hub futures contract reached a record 1.73 million contracts on October 30,...

Sleep is likely a whole-brain phenomenon, with most of the brain probably benefiting from this state of decreased arousal. Recent advances in our understanding of some potential sleep functions, such as metabolite clearance and synaptic homeostasis, make it evident why the whole brain is likely impacted by sleep: All neurons have synapses, and all neurons produce waste metabolites. Sleep experiments in the fly Drosophila melanogaster suggest that diverse sleep functions appear to be conserved across all animals. Studies of brain activity during sleep in humans typically involve multidimensional data sets, such as those acquired by electroencephalograms (EEGs) or functional magnetic resonance imaging (fMRI), and these whole-brain read-outs often reveal important qualities of different sleep stages, such as changes in frequency dynamics or connectivity. Recently, various techniques have been developed that allow for the recording of neural activity simultaneously across multiple regions of the fly brain. These whole-brain-recording approaches will be important for better understanding sleep physiology and function, as they provide a more comprehensive view of neural dynamics during sleep and wake in a relevant model system. Here, we present a brief summary of some of the findings derived from sleep activity recording studies in sleeping Drosophila flies and discuss the value of electrophysiological versus calcium imaging techniques. Although these involve very different preparations, they both highlight the value of multidimensional data for studying sleep in this model system, like the use of both EEG and fMRI in humans.

The establishment of neural connectivity is a major part of neural development. The central nervous system (CNS) midline is the most characterized axon guidance choice point, and work in Drosophila has played a pivotal role in understanding the molecular mechanisms responsible. Axons respond to attractive cues such as Netrin via the Frazzled receptor, and repulsive cues such as Slit via Robo receptors. Both signals are expressed at the CNS midline, affect pioneer axons, and have dramatic effects on the axon scaffold as a whole. Here, we focus on previous research analyzing classic mutants in the Slit/Robo pathway, which can readily be detected with a dissecting microscope. We also discuss analyzing these mutants in a teaching lab situation. The combination of sophisticated genetics and reliable axonal markers in Drosophila allows phenotypic analysis to be performed at the single-cell level. The elaborate architecture of neurons is very sensitive to disruption by genetic mutations, allowing the effects of novel mutations to be easily detected and assessed.

Analysis of taste sensory responses has been a powerful approach for understanding principles of taste detection and coding. The shared architecture of external taste sensing units, called sensilla, in insects opened up the study of tastant-evoked responses in any model of choice using a single-sensillum tip recording method that was developed in the mid-1900s. Early studies in blowflies were instrumental for identifying distinct taste neurons based on their responses to specific categories of chemicals. Broader system-wide analyses of whole organs have since been performed in the genetic model insect Drosophila melanogaster, revealing principles of stereotypical organization and function that appear to be evolutionarily conserved. Although limited in scope, investigations of taste sensory responses in mosquitoes showcase conservation in sensillar organization, as well as in groupings of functionally distinct taste neurons in each sensillum. The field is now poised for more thorough dissections of mosquito taste function, which should be of immense value in understanding close-range chemosensory interactions of mosquitoes with their hosts and environment. Here, we provide an introduction to the basic structure of a taste sensillum and functional analysis of the chemosensory neurons within it.

Transposon-mediated transgenesis of mosquito vectors of disease pathogens followed the early success of transgenesis in the vinegar fly, Drosophila melanogaster. The P transposable element used in Drosophila does not function canonically in mosquitoes, and repeatable, routine transgenesis in mosquitoes was not accomplished until new transposable elements were discovered and validated. A number of distinct transposons were subsequently identified that mediate the introduction of exogenous DNA in a stable and heritable manner in mosquito species, including members of the genera Aedes, Anopheles, and Culex. The most versatile element, piggyBac, is functional in all of these mosquito genera, as well as in many other insects in diverse orders, and has been used extensively outside the class. Transposon-mediated transgenesis of recessive and dominant marker genes and reporter systems has been used to define functional fragments of gene control sequences, introduce exogenous DNA encoding products beneficial to medical interests, and act as "enhancer traps" to identify endogenous genes with specific expression characteristics.

Volker (OM Montenegro) describes how their outdoor lessons for Roma kids were threatened by bad weather. Then God provided not only the solution - building a carport as a shelter - but also the funds and manpower needed to build it.

Pioneering Technology Allows Surgeons to Cut Precisely and Control Bleeding Without Causing Heat Damage to Tissue

Centuries-old university standardizes on SolidWorks Education Edition software so students can learn CAD and design validation skills

Knee replacement doesn’t have to be ‘total’

Flagship Data Management Solution Introduces‘Item-Centric’ PDM and New BOM Functionality

Quick design turnaround and easy documentation process help UK-based company move products to market faster

Robotics programmers can now use SolidWorks 3D CAD models for more powerful simulations

R&D ‘Sandbox’ Previews Some Potential Capabilities for 3D CAD Software

Switch to SolidWorks 3D CAD and Simulation Software Delivers Productivity Increase over AutoCAD

Sir Richard Branson, Jeff Ray, Jon Hirschtick, and World-Class Companies to Shine at World’s Largest Annual SolidWorks Gathering

2008 Class 1 World Powerboat Champions Design Faster Boats Using SolidWorks 3D CAD and Simulation Software

Austrian manufacturer also optimizes creation of assembly documentation and related bills of material

Eliminates the Cost and Complexity of Maintaining Online Parts Catalogs; Improves Search, Navigation, and Communication for Engineers Seeking 3D Part Models

SolidWorks World 2009 Wraps Up Exhilarating Week of Learning and Networking

Control Engineering Recognizes SolidWorks® 2009 for Design Simulation

Free SolidWorks 3D CAD Software, Training, and Certification will Build Valuable New Skills Employers Need

Business-Critical Solutions are Now Free to any Subscriber for an Additional Year

Solutions Catch Problems Early and Drive Cost Out of Designs

New Licensing, Support Programs For Certification Accompany Software Upgrades

Leading elevator components supplier implements 550 licenses of the SolidWorks PDM solution

One Of Only Four Companies To Place Among Top Employers In Each Year Of The Publication’s Survey

Maker of NHL Hockey Boards Uses SolidWorks and Robotics to Speed Production by More than 60 Percent

Displaced Workers Get Free SolidWorks CAD Software,Learn It, and Obtain New Jobs

Integrated Tools Make Mechatronics-Oriented Design and Seamless Deployment to Hardware Easy

Leading CAD Software Optimizes Core Design Functions for an Improved Design Experience

3D CAD Software’s Superior Data Translation Capabilities Support Growth of Tech Publishing and Engineering Services

SolidWorks’ ‘Balance of Ease of Use and Powerful Capabilities’Prompts Rapid Expansion of Student Access

Non-Profit Cooperative Assembled Virtual Team to Prove $1,000 Incubator Was Possible, Safe, and Reliable

SolidWorks Drives Custom 3D CAD Models, Helping the Company Outperform Competition

Engineers Use 3D CAD and Simulation To Customize Products With Quick Modifications, Testing, and Demonstrations

367.382 mph in a Two-Wheeled Missile

Curventa and RuRoc Adapt Original Design for Formula One Pit Crew Safety Wear