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Letter to survivors / by Gébé; translated and with an introduction by Edward Gauvin ; english lettering by Francois Vigneault

By library.mit.edu
Published On :: Sun, 26 Apr 2020 07:06:33 EDT

Barker Library - PN6747.G4 L4813 2018


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A biodegradable CO2-based polymeric antitumor nanodrug via a one-pot surfactant- and solvent-free miniemulsion preparation

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Biomater. Sci., 2020, 8,2234-2244
DOI: 10.1039/C9BM01931F, Paper
Qiaojie Luo, Xiaojun Li, Ying Wang, Jianfang He, Qiao Zhang, Pengfei Ge, Xia Cai, Qiang Sun, Weipu Zhu, Zhiquan Shen, Xiaodong Li
A biodegradable CO2-based polymeric nanodrug is obtained via a surfactant- and solvent-free miniemulsion preparation, which can be concentrated at tumor site by EPR and releases the encapsulated drug through pH responsiveness.
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A polymeric nanocarrier with a tumor acidity-activatable arginine-rich (R9) peptide for enhanced drug delivery

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Biomater. Sci., 2020, 8,2255-2263
DOI: 10.1039/D0BM00069H, Paper
Liting Zhang, Chengtao Jiang, Fanjun Zeng, Haiyu Zhou, Dongdong Li, Xinyu He, Song Shen, Xianzhu Yang, Jun Wang
The cell-penetrating function of R9 peptide of DA@R9-NPDOX was masked in the blood circulation, while reactivated in tumor tissue for enhanced tumor cellular uptake.
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Ultra pH-sensitive polymeric nanovesicles co-deliver doxorubicin and navitoclax for synergetic therapy of endometrial carcinoma

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Biomater. Sci., 2020, 8,2264-2273
DOI: 10.1039/D0BM00112K, Paper
Jie Ding, Xu Zhang, Chuangqi Chen, Yuqiang Huang, Xingsu Yu, Xiaomao Li
An ultra pH-sensitive polymeric nanovesicle was constructed to co-deliver doxorubicin and navitoclax for highly efficient synergetic treatment of endometrial carcinoma.
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Two-step tumor-targeting therapy via integrating metabolic lipid-engineering with in situ click chemistry

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Biomater. Sci., 2020, 8,2283-2288
DOI: 10.1039/D0BM00088D, Paper
Guihong Lu, Liping Zuo, Jinfeng Zhang, Houshun Zhu, Wanru Zhuang, Wei Wei, Hai-Yan Xie
A highly efficient two-step targeting strategy integrating metabolic lipid-engineering with in situ click chemistry is developed, thus significantly improved the tumor theranostic performance of the red blood cells ghosts based drug delivery.
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MT1-MMP activatable fluorogenic probes with enhanced specificity via high-affinity peptide conjugation for tumor imaging

By pubs.rsc.org
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Biomater. Sci., 2020, 8,2308-2317
DOI: 10.1039/C9BM02007A, Paper
Xiuru Ji, Shuping Xie, Yan Jiao, Xiaojuan Zhang, Duxin Sun, Victor C. Yang, Mei Wang, Huining He, Lu Sun
A novel MT1-MMP activatable fluorogenic probe for tumor detection with enhanced specificity was developed via high-affinity and specific peptide conjugation.
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Hydrophilic titanium surfaces reduce neutrophil inflammatory response and NETosis

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Biomater. Sci., 2020, 8,2289-2299
DOI: 10.1039/C9BM01474H, Paper
Open Access
Jefferson O. Abaricia, Arth H. Shah, Ryan M. Musselman, Rene Olivares-Navarrete
Neutrophils are sensitive to biomaterial surface properties, controlling activation and inflammatory microenvironment, revealing a novel target for enhancing biomaterial integration.
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Methylcellulose – a versatile printing material that enables biofabrication of tissue equivalents with high shape fidelity

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Biomater. Sci., 2020, 8,2102-2110
DOI: 10.1039/D0BM00027B, Minireview
Open Access
T. Ahlfeld, V. Guduric, S. Duin, A. R. Akkineni, K. Schütz, D. Kilian, J. Emmermacher, N. Cubo-Mateo, S. Dani, M. v. Witzleben, J. Spangenberg, R. Abdelgaber, R. F. Richter, A. Lode, M. Gelinsky
This minireview highlights the use of the polysaccharide methylcellulose for biofabrication applications. Its properties are useful for printing of dissolvable support structures as well as the development of novel bioinks.
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Cu, Zn doped borate bioactive glasses: antibacterial efficacy and dose-dependent in vitro modulation of murine dendritic cells

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Biomater. Sci., 2020, 8,2143-2155
DOI: 10.1039/C9BM01691K, Paper
Open Access
Katharina Schuhladen, Lena Stich, Jochen Schmidt, Alexander Steinkasserer, Aldo R. Boccaccini, Elisabeth Zinser
Bioactive borate glasses additionally doped with copper and/or zinc have enthralling immune-modulatory effects on immune cells.
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Balancing the thickness of sensitizing and inert layers in neodymium-sensitized tetralayer nanoconstructs for optimal ultraviolet upconversion and near-infrared cross-linked hydrogel tissue sealants

By pubs.rsc.org
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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00453G, Paper
Zhongzheng Yu, Yong Yao Chun, Jingwen Xue, Jodie Zu Yi Tan, Wen Kiat Chan, Weizheng Cai, Yan Zhang, Timothy Thatt Yang Tan
Balancing the thickness of sensitizing and inert layers in neodymium-sensitized tetralayer nanoconstructs for optimal ultraviolet upconversion.
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A bioartificial liver support system integrated with a DLM/GelMA-based bioengineered whole liver for prevention of hepatic encephalopathy via enhanced ammonia reduction

By pubs.rsc.org
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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/C9BM01879D, Paper
Guohua Wu, Di Wu, James Lo, Yimin Wang, Jianguo Wu, Siming Lu, Han Xu, Xin Zhao, Yong He, Jun Li, Utkan Demirci, Shuqi Wang
The developed bioartificial liver support system integrated with the decellularized liver matrix/GelMA-based bioengineered whole liver can potentially help elevate liver functions and prevent hepatic encephalopathy via enhanced ammonia reduction.
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Influence of the mechanical properties of biomaterials on degradability, cell behaviors and signaling pathways: current progress and challenges

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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00269K, Review Article
Lu Wang, Cunyang Wang, Shuai Wu, Yubo Fan, Xiaoming Li
We have clarified the influence of the mechanical properties of biomaterials on degradability and cell response, and also mechanical design targets and approaches.
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High antimicrobial photodynamic activity of photosensitizer encapsulated dual-functional metallocatanionic vesicles against drug-resistant bacteria S. aureus

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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00323A, Paper
Bunty Sharma, Gurpreet Kaur, Ganga Ram Chaudhary, Santosh L. Gawali, P. A. Hassan
Developments in the field of photodynamic therapy (PDT) are being made by investigating appropriate photosensitizers (PSs) and enhancing the penetration effect of light by developing new metallocatanionic vesicles.
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Arbitrarily-shaped microgels composed of chemically unmodified biopolymers

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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/C9BM02056J, Paper
Yadu N. Vakkipurath Kodakkadan, Kristyna Idzakovicova, Josef Sepitka, Daniël ten Napel, Eric Safai, Petr Cigler, Frantisek Štěpánek, Ivan Rehor
We introduce a method for photolithographic synthesis of arbitrarily shaped microgels composed purely of a biopolymer of choice.
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Bacterial nanocellulose as a corneal bandage material: a comparison with amniotic membrane

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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00083C, Paper
Open Access
Irene Anton-Sales, Justin Christopher D'Antin, Jorge Fernández-Engroba, Victor Charoenrook, Anna Laromaine, Anna Roig, Ralph Michael
Bacterial nanocellulose exhibits valuable properties to act as a corneal bandage material in terms of conformability, suturability, durability and ease of manipulation in ophthalmological environments.
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In situ preparation of gold–polyester nanoparticles for biomedical imaging

By pubs.rsc.org
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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00175A, Paper
Mohamed F. Attia, Meenakshi Ranasinghe, Roman Akasov, Jeffrey N. Anker, Daniel C. Whitehead, Frank Alexis
Hybrid gold-polyester nanoparticles were synthesized by UV irradiation of a gold salt and photoinitiator encapsulated in a polyester nanoparticle. The resulting materials exhibit excellent cellular imaging and surface plasmon resonance properties.
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Matrix stiffness-regulated cellular functions under different dimensionalities

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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/C9BM01809C, Review Article
Jiajun Zhong, Yuexiong Yang, Liqiong Liao, Chao Zhang
The microenvironments that cells encounter with in vitro.
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Polydopamine-assisted one-step modification of nanofiber surfaces with adenosine to tune the osteogenic differentiation of mesenchymal stem cells and the maturation of osteoclasts

By pubs.rsc.org
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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/C9BM01990A, Paper
Taufiq Ahmad, Hayeon Byun, Hyeok Jun Shin, Jinkyu Lee, Sajeesh Kumar Madhurakkat Perikamana, Eun Mi Kim, Young Min Shin, Heungsoo Shin
Adenosine and its receptors have emerged as alternative targets to control cellular functions for bone healing.
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The potential role of borophene as a radiosensitizer in boron neutron capture therapy (BNCT) and particle therapy (PT)

By pubs.rsc.org
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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00318B, Communication
Pengyuan Qi, Qianyuan Chen, Dong Tu, Songhuan Yao, Yupeng Zhang, Jike Wang, Conghua Xie, Chunxu Pan, Hao Peng
The potential role of borophene as a radiosensitizer in PT and BNCT was investigated.
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An engineered exosome for delivering sgRNA:Cas9 ribonucleoprotein complex and genome editing in recipient cells

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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00427H, Paper
Yangyang Ye, Xiang Zhang, Fei Xie, Bin Xu, Ping Xie, Ting Yang, Qian Shi, Chen-Yu Zhang, Yujing Zhang, Jiangning Chen, Xiaohong Jiang, Jing Li
CRISPR-Cas9 components delivered by engineered exosomes achieve genome editing in recipient cells.
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Enhanced nanoparticle accumulation by tumor-acidity-activatable release of sildenafil to induce vasodilation

By pubs.rsc.org
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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00466A, Paper
Peng Zhang, Yu Zhang, Xiaoya Ding, Chunsheng Xiao, Xuesi Chen
An efficient strategy to selectively promote nanoparticle accumulation in solid tumors was developed by encapsulating sildenafil in cisplatin-incorporated polymeric micelles.
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Dendritic cells reprogrammed by CEA messenger RNA loaded multi-functional silica nanospheres for imaging-guided cancer immunotherapy

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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00395F, Communication
Yue Hu, Yuyin Tang, Xiao-Jing Zhang, Xiao-Tong Yang, Ying-Ying Tang, Su Li, Linyu Hu, Peng Chen, Dong Zhu
Multi-functional and hierarchically structured silica nanospheres are rationally designed and fabricated, which encapsulate quantum dots to permit near infrared deep tissue imaging and are loaded with carcinoembryonic antigen messenger RNA (CEAmRNA) to enable stable and abundant antigen expression in DCs.
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A photothermal-hypoxia sequentially activatable phase-change nanoagent for mitochondria-targeting tumor synergistic therapy

By pubs.rsc.org
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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00003E, Paper
Jia Qu, Dengke Teng, Guoqing Sui, Shihui Guan, Yang Wang, Qimeihui Wang, Yuanqiang Lin, Haitao Ran, Zhigang Wang, Hui Wang
The advantages of PCM@Lip/IT NPs include mitochondrial-targeting, on-demand drug release, and prodrug activation by hypoxia with guidance/monitoring by PA and FL imaging.
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Sustainable release of vancomycin from micro-arc oxidised 3D-printed porous Ti6Al4V for treating methicillin-resistant Staphylococcus aureus bone infection and enhancing osteogenesis in a rabbit tibia osteomyelitis model

By pubs.rsc.org
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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/C9BM01968E, Paper
Teng Zhang, Qingguang Wei, Hua Zhou, Wenhao Zhou, Daoyang Fan, Xinhong Lin, Zehao Jing, Hong Cai, Yan Cheng, Xiaoguang Liu, Weishi Li, Chunli Song, Yun Tian, Nanfang Xu, Yufeng Zheng, Zhongjun Liu
Sustainable release of vancomycin from micro-arc oxidised 3D-printed porous Ti6A14V for treating MRSA bone infection and enhancing osteogenesis.
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A Fe3+-crosslinked pyrogallol-tethered gelatin adhesive hydrogel with antibacterial activity for wound healing

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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00188K, Paper
Ning Han, Ziyang Xu, Chunyan Cui, Yuan Li, Dongfei Zhang, Meng Xiao, Chuanchuan Fan, Tengling Wu, Jianhai Yang, Wenguang Liu
A tunicate-inspired gelatin-based hydrogel prepared by a simple mixing method, exhibits strong adhesion and antibacterial capacity, and facilitates wound healing.
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ZBTB20-mediated titanium particle-induced peri-implant osteolysis by promoting macrophage inflammatory responses

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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00147C, Paper
Open Access
Junxiong Qiu, Peng Peng, Min Xin, Zhenkang Wen, Zhong Chen, Sipeng Lin, Manyuan Kuang, Yuan Fu, Guibin Fang, Shixun Li, Changchuan Li, Jiaji Mao, Ling Qin, Yue Ding
Aseptic loosening (AL) caused by wear particles released from implant surfaces is one of the main causes for the failure of artificial joints, which is initiated by macrophage inflammatory responses.
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Additively manufactured functionally graded biodegradable porous zinc

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Biomater. Sci., 2020, 8,2404-2419
DOI: 10.1039/C9BM01904A, Paper
Open Access
Y. Li, P. Pavanram, J. Zhou, K. Lietaert, F. S. L. Bobbert, Yusuke Kubo, M. A. Leeflang, H. Jahr, A. A. Zadpoor
First report on the effect of topology design on the biodegradation, mechanical properties, and cell responses of additively manufactured Zn.
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In situ conversion of rose bengal microbubbles into nanoparticles for ultrasound imaging guided sonodynamic therapy with enhanced antitumor efficacy

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Biomater. Sci., 2020, 8,2526-2536
DOI: 10.1039/C9BM02046B, Paper
Rui Hou, Xiaolong Liang, Xiaoda Li, Xu Zhang, Xiaotu Ma, Fan Wang
Sonosensitizer microbubbles enhance drug accumulation and the antitumor efficacy of sonodynamic therapy by ultrasound mediated micro to nano conversion.
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A riboflavin–ultraviolet light A-crosslinked decellularized heart valve for improved biomechanical properties, stability, and biocompatibility

By pubs.rsc.org
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Biomater. Sci., 2020, 8,2549-2563
DOI: 10.1039/C9BM01956A, Paper
Chungeng Liu, Weihua Qiao, Hong Cao, Jinchi Dai, Fei Li, Jiawei Shi, Nianguo Dong
Riboflavin–ultraviolet light A could effectively crosslink a decellularized heart valve to improve its biomechanical properties, stability and biocompatibility.
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Tumor localization of oncolytic adenovirus assisted by pH-degradable microgels with JQ1-mediated boosting replication and PD-L1 suppression for enhanced cancer therapy

By pubs.rsc.org
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Biomater. Sci., 2020, 8,2472-2480
DOI: 10.1039/D0BM00172D, Paper
Haishi Qiao, Xingmei Chen, Qiming Wang, Junmei Zhang, Dechun Huang, Enping Chen, Hongliang Qian, Yinan Zhong, Qi Tang, Wei Chen
Illustration of pH-degradable microgels (MGs) for the simultaneous encapsulation of OA and JQ1 for an enhanced oncolytic viral treatment with JQ1-meidated boosting viral replication and PD-L1 suppression.
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Engineering red-emitting multi-functional nanocapsules for magnetic tumour targeting and imaging

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Biomater. Sci., 2020, 8,2590-2599
DOI: 10.1039/D0BM00314J, Paper
Julie Tzu-Wen Wang, Umberto Martino, Rehan Khan, Maasoomeh Bazzar, Paul Southern, Dönüş Tuncel, Khuloud T. Al-Jamal
Self-red-emitting magnetic PLGA-PEG nanocapsules for optical imaging and magnetic tumour targeting.
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Super-assembled core/shell fibrous frameworks with dual growth factors for in situ cementum–ligament–bone complex regeneration

By pubs.rsc.org
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Biomater. Sci., 2020, 8,2459-2471
DOI: 10.1039/D0BM00102C, Paper
Tian Ding, Jianhua Li, Xingshuang Zhang, Lingqian Du, Yang Li, Dengwang Li, Biao Kong, Shaohua Ge
In this work, a super-assembled framework (SAF) was fabricated to achieve sequential delivery of bFGF and BMP-2 for in situ cementum–ligament–bone complex regeneration.
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A nanosystem loaded with perfluorohexane and rose bengal coupled upconversion nanoparticles for multimodal imaging and synergetic chemo-photodynamic therapy of cancer

By pubs.rsc.org
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Biomater. Sci., 2020, 8,2488-2506
DOI: 10.1039/C9BM02081K, Paper
Hai-yan Wang, Li Hou, Hai-liang Li, Xu Wang, Yang Cao, Bo-yu Zhang, Jing-tao Wang, Shi-jie Wei, Hong-wan Dang, Hai-tao Ran
A novel nanosystem (FURH-PFH-NPs) combined with LIFU and laser irradiation realized multimodal imaging, targeted release of HCPT, UCNPs-RB and synergetic chemo-photodynamic therapy of cancer.
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Enhanced selectivity, cellular uptake, and in vitro activity of an intrinsically fluorescent copper–tirapazamine nanocomplex for hypoxia targeted therapy in prostate cancer

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Biomater. Sci., 2020, 8,2420-2433
DOI: 10.1039/C9BM01905G, Paper
Vera L. Silva, Abdessamad Kaassis, Ashkan Dehsorkhi, Cédrik-Roland Koffi, Maja Severic, Moustafa Abdelhamid, Duuamene Nyimanu, Christopher J. Morris, Wafa’ T. Al-Jamal
Cu(TPZ)2 complex as a promising hypoxia selective cytotoxin in prostate cancer.
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Assembly of FN-silk with laminin-521 to integrate hPSCs into a three-dimensional culture for neural differentiation

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Biomater. Sci., 2020, 8,2514-2525
DOI: 10.1039/C9BM01624D, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Carolina Åstrand, Veronique Chotteau, Anna Falk, My Hedhammar
The functionalized recombinant spider silk protein FN-silk can self-assemble into a 3D microfiber network. When combined with recombinant laminin521 it provides a 3D culture system suitable for expansion of hPSCs and following neural differentiation.
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Injectable hydrogel systems with multiple biophysical and biochemical cues for bone regeneration

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Biomater. Sci., 2020, 8,2537-2548
DOI: 10.1039/D0BM00104J, Paper
Weinan Cheng, Zhaozhao Ding, Xin Zheng, Qiang Lu, Xiangdong Kong, Xiaozhong Zhou, Guozhong Lu, David L. Kaplan
Tunable multiple angiogenic and osteogenic cues were introduced into hydrogel systems simultaneously to optimize the niches for bone regeneration.
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NIR-emitting semiconducting polymer nanoparticles for in vivo two-photon vascular imaging

By pubs.rsc.org
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Biomater. Sci., 2020, 8,2666-2672
DOI: 10.1039/C9BM02063B, Paper
Xiao-Ting Gong, Wenguang Xie, Jing-Jing Cao, Shengxiang Zhang, Kanyi Pu, Hao-Li Zhang
A NIR-emitting TPF probe (NESPN) was prepared using semiconducting polymers and used for continuously monitoring the whole process of ischemic stroke and subsequent reperfusion. This work provides a new and versatile tool for vascular research and diagnosis of vascular diseases.
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The electrospinning of a thermo-responsive polymer with peptide conjugates for phenotype support and extracellular matrix production of therapeutically relevant mammalian cells

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Biomater. Sci., 2020, 8,2611-2626
DOI: 10.1039/C9BM01965K, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
F. A. A. Ruiter, L. E. Sidney, K. L. Kiick, J. I. Segal, C. Alexander, F. R. A. J. Rose
The fabrication and application of a biocompatible peptide conjugated thermo-responsive fibrous scaffolds for cellular phenotype support and enzymatic-free passaging of mammalian cells.
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Biodegradable nanocomposite fibrous scaffold mediated local delivery of vancomycin for the treatment of MRSA infected experimental osteomyelitis

By pubs.rsc.org
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Biomater. Sci., 2020, 8,2653-2665
DOI: 10.1039/D0BM00140F, Paper
Amit G. Krishnan, Raja Biswas, Deepthy Menon, Manitha B. Nair
The study shows the development of a biodegradable bi-functional composite scaffold that can reduce bacterial infection, while promotes bone regeneration in osteomyelitis, without the need for revision surgery.
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Interfacing human induced pluripotent stem cell-derived neurons with designed nanowire arrays as a future platform for medical applications

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Biomater. Sci., 2020, 8,2434-2446
DOI: 10.1039/D0BM00182A, Paper
Jann Harberts, Undine Haferkamp, Stefanie Haugg, Cornelius Fendler, Dennis Lam, Robert Zierold, Ole Pless, Robert H. Blick
Nanostructured substrates such as nanowire arrays form a powerful tool for building next-generation medical devices.
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An intelligent vancomycin release system for preventing surgical site infections of bone tissues

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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00255K, Paper
Yuan Li, Guang Li, Xiaoling Sha, Litao Li, Kuo Zhang, Daohong Liu, Yanfei Hao, Xu Cui, Lei Wang, Hao Wang
An intelligent anti-bacterial system can be constructed on implants during surgery.
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A multifunctional metal-biopolymer coordinated double network hydrogel combined with multi-stimulus responsiveness, self-healing, shape memory and antibacterial properties

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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00425A, Paper
Kun Yan, Feiyang Xu, Chunyu Wang, Yingying Li, Yuanli Chen, Xiufang Li, Zhentan Lu, Dong Wang
A universal, straightforward macroscale assembly technology has been presented for fabrication of polysaccharide-based multifunctional DN gels based on metal coordination chemistry.
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A versatile ultrafine and super-absorptive H+-modified montmorillonite: application for metabolic syndrome intervention and gastric mucosal protection

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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00474J, Paper
Qiwen Wang, Jie Shen, Enqi Mo, Haotian Zhang, Jianwei Wang, Xiurong Hu, Jun Zhou, Hongzhen Bai, Guping Tang
An H+-modified montmorillonite (H-MMT) was prepared using an acid modification method to obtain powerful absorption ability as a theranostic platform for both metabolic syndrome and gastric mucosa protection.
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Coupling PEG-LZM Polymer Network with Polyphenol Yields Suturable Biohydrogel for Tissue Patching

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Biomater. Sci., 2020, Accepted Manuscript
DOI: 10.1039/D0BM00429D, Paper
Haoqi Tan, Junjie Sun, Dawei Jin, Jialin Song, Miao Lei, Artem Antoshin, Xin Chen, Meng Yin, Xue Qu, Changsheng Liu
Poor mechanical performances severely limit the application of hydrogel in vivo, for example, it is difficult to perform a very common suturing operation on hydrogel during surgery. There is a...
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Surface engineering of titanium alloy using metal-polyphenol network coating with magnesium ions for improved osseointegration

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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00566E, Paper
Sangmin Lee, Yun-Young Chang, Jinkyu Lee, Sajeesh Kumar Madhurakkat Perikamana, Eun Mi Kim, Yang-Hun Jung, Jeong-Ho Yun, Heungsoo Shin
Although titanium-based implants are widely used in orthopedic and dental clinics, improved osseointegration at the bone–implant interface is still required.
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A biomimetic orally targeted delivery of Bindarit for immunotherapy of atherosclerosis

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Biomater. Sci., 2020, Accepted Manuscript
DOI: 10.1039/D0BM00418A, Paper
Luqi Yin, Cuiping Peng, Yue Tang, Yuchuan Yuan, Jiaxing Liu, Tingting Xiang, Feila Liu, Zhou Xing, Xiaohui Li
Monocyte chemoattractant protein-1 (MCP-1) plays an important role in the development of atherosclerosis. However, the application of bindarit (a specific synthetic inhibitor of MCP-1) in atherosclerosis has not been confirmed...
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Integrated network pharmacology and targeted metabolomics to reveal the mechanism of nephrotoxicity of triptolide

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Toxicol. Res., 2019, 8,850-861
DOI: 10.1039/C9TX00067D, Paper
Wei Huang, Chuanxin Liu, Lijuan Xie, Yuming Wang, Yanyan Xu, Yubo Li
Integrated network pharmacology and targeted metabolomics to reveal the nephrotoxicity mechanism of triptolide.
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Eco-friendly synthesis of glutathione-capped CdTe/CdSe/ZnSe core/double shell quantum dots: their cytotoxicity and genotoxicity effects on Chinese hamster ovary cells

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Toxicol. Res., 2019, 8,868-874
DOI: 10.1039/C9TX00113A, Paper
Neo Mervyn Monaheng, Sundararajan Parani, Mary Gulumian, Oluwatobi Samuel Oluwafemi
In this work, we report green one-pot synthesis, cytotoxicity and genotoxicity of glutathione-capped CdTe/CdSe/ZnSe heterostructured quantum dots (QDs) using a label-free xCELLigence RTCA system as well as the Cytokinesis Blocked Micronucleus assay.
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miR-140-5p mediates bevacizumab-induced cytotoxicity to cardiomyocytes by targeting the VEGFA/14-3-3γ signal pathway

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Toxicol. Res., 2019, 8,875-884
DOI: 10.1039/C9TX00100J, Paper
Xuan-Ying Chen, Wei-Lin Huang, Xiao-Ping Peng, Yan-Ni Lv, Jun-He Li, Jian-Ping Xiong
Bevacizumab (BVZ) is a widely investigated angiogenesis inhibitor in cancer patients. Although the anti-tumor effects has been verified, cardiotoxicity may be the most serious side-effect for BVZ.
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Characteristic synergistic cytotoxic effects toward cells in graphene oxide dressing with cadmium and copper ions

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Toxicol. Res., 2019, 8,908-917
DOI: 10.1039/C9TX00146H, Paper
Yiyang Dong, Yulin Chang, Haidi Gao, Victoria Arantza León Anchustegui, Qiang Yu, Haifang Wang, Jia-Hui Liu, Shihui Wang
Cadmium ions exerted synergistic toxic effects with graphene oxide on Hela cells.
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