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Phenylboronic acid modification-based novel dumbbell-shaped Au–Ag nanorod SERS substrates for ultrasensitive detection of SO42−

Anal. Methods, 2024, 16,2311-2321
DOI: 10.1039/D3AY01831H, Paper
Kang Shen, Caili Bi, Haifan Yang, Miaowen Xu, Lili Huang, Youwei Wang
Based on the coordination principle of Lewis acids, a novel 4-MPBA-modified dumbbell-shaped Au–Ag nanorod (4-MPBA@DS Au–AgNR) SERS substrate was developed to realize the high sensitivity and specificity of SO42− detection.
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Advancements in the development of fluorescent chemosensors based on CN bond isomerization/modulation mechanistic approaches

Anal. Methods, 2024, 16,2198-2228
DOI: 10.1039/D3AY02321D, Critical Review
Arpna Tamrakar, Manzoor Ahmad Wani, Gargi Mishra, Ankur Srivastava, Rampal Pandey, Mrituanjay D. Pandey
The CN bond isomerization/modulation as a fluorescence signalling mechanism was explored by studying the photophysical properties of conformationally restricted molecules.
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Characterizing a visual lateral flow device for rapid SARS-CoV-2 virus protein detection: pre-clinical and system assessment

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D3AY02075D, Paper
Natpapas Wiriyachaiporn, Jetnapang Kongrueng, Kannika Sukkuea, Rattana Tanrattanawong, Jarunee Vanichtanankul, Thanaya Saeyang, Tararat Jantra, Deanpen Japrung, Weerakanya Maneeprakorn, Suwussa Bamrungsap, Pareena Janchompoo, Ekawat Pasomsub
Analytical and pre-clinical evaluation of a visual screening lateral flow device for SARS-CoV-2 virus protein detection and its system characterization.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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A complementary method with PFBBr-derivatization based on a GC-EI-MS platform for the simultaneous quantitation of short-, medium- and long-chain fatty acids in murine plasma and feces samples

Anal. Methods, 2024, 16,2330-2339
DOI: 10.1039/D3AY02271D, Paper
Hong-Xu Zhou, Qing Jiang, Xin He, Xian Fu, Jun-Yan Liu
Fatty acids (FAs) are essential molecules in all organisms and are involved in various physiological and pathophysiological processes.
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Dual-functional porphyrinic zirconium-based metal–organic framework for the fluorescent sensing of histidine enantiomers and Hg2+

Anal. Methods, 2024, 16,2386-2399
DOI: 10.1039/D3AY02241B, Paper
Shili Qin, Fanshu Meng, Fenglong Jin, Xidi Xu, Ming Zhao, Hongtao Chu, Lidi Gao, Shuren Liu
L-Cys/PCN-222 as a novel and dual-functional fluorescent sensor was developed. It not only showed a higher chiral fluorescent recognition of L-histidine but also performed as a visual sensor for Hg2+ in actual surface water.
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Solvation effect enabled visualized discrimination of multiple metal ions

Anal. Methods, 2024, 16,2301-2310
DOI: 10.1039/D4AY00060A, Paper
Yang Cheng, Yuan Liu, Jiguang Li, Yudong Li, Da Lei, Dezhong Li, Xincun Dou
Highly efficient detection of environmental residual potentially toxic species is of concern worldwide as their presence in an excessive amount would greatly endanger the health of human beings as well as environmental sustainability.
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Construction of coumarin-appended calix[4]arene-based fluorescence sensor for the detection of carbofuran in cabbage

Anal. Methods, 2024, 16,2400-2411
DOI: 10.1039/D4AY00030G, Paper
Heni Soni, Nidhi Verma, Divyesh Y. Chaudhari, Sahaj A. Gandhi, Alok Pandya, Pinkesh G. Sutariya
This study presents a novel approach for the detection of carbofuran (CBF) insecticide by exploring a calix[4]arene-derived fluorescence probe, CouC4S, functionalized with two coumarin-labelled at the narrow edge of the calix[4]arene platform.
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Fe3+-induced luminescence quenching in carbon dots – mechanism unveiled

Anal. Methods, 2024, 16,2349-2358
DOI: 10.1039/D3AY02202A, Paper
Varsha Raveendran P.T., Anjali C., Renuka Neeroli Kizhakayil
Luminescence quenching in carbon dots with an increase in Fe3+ concentration and the quantitative variation in luminescence intensity with added ferric ions.
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Anti-aggregation colorimetric sensing of cysteine using silver nanoparticles in the presence of Pb2+

Anal. Methods, 2024, 16,2378-2385
DOI: 10.1039/D4AY00351A, Paper
Lihui Mao, Yi Zhang, Huan Zhang, Huili Liu, Yong-ping Gao
In this study, an unmodified AgNPs was synthesized to prepare AgNPs-Pb2+ as a probe for colorimetric sensing of cysteine. We developed a AgNPs colorimetric method for the determination of cysteine in urine, utilizing the anti-aggregation principle.
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On-chip light sheet illumination for nanoparticle tracking in microfluidic channels

Anal. Methods, 2024, 16,2229-2240
DOI: 10.1039/D3AY02290K, Communication
Théo Travers, Gaétan Delhaye, Martinus H. V. Werts, Denis Gindre, Matthieu Loumaigne
A simple and inexpensive method is presented to efficiently integrate light sheet illumination in a microfluidic chip for dark-field microscopic tracking and sizing of nanoparticles.
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A chemiluminescence immunoassay for type IV collagen as a promising marker for liver fibrosis and cirrhosis

Anal. Methods, 2024, 16,2248-2255
DOI: 10.1039/D3AY02240D, Paper
Xiaoling Fu, Fan Zhang, Fangda Zhen, Lian Duan, Jian Zhou, Jianguo Ma
Herein, a magnetic bead-based chemiluminescence assay is reported to detect type IV collagen (col-IV) in serum samples.
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Analysing micro- and nanoplastics with cutting-edge infrared spectroscopy techniques: a critical review

Anal. Methods, 2024, 16,2177-2197
DOI: 10.1039/D3AY01808C, Critical Review
Open Access
Junhao Xie, Aoife Gowen, Wei Xu, Junli Xu
In this review, we discussed and compared the applications of Fourier transform infrared spectroscopy, quantum cascade laser infrared spectroscopy, atomic force microscopy-based infrared spectroscopy, and optical photothermal infrared spectroscopy in MNP research from multiple perspectives.
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An overview of electrochemical biosensors used for COVID-19 detection

Anal. Methods, 2024, 16,2164-2176
DOI: 10.1039/D3AY02042H, Minireview
Tatiana Lima Valerio, Raquel Anastácio, Stella Schuster da Silva, Carolina Camargo de Oliveira, Marcio Vidotti
This short review presents the latest advances in the field of electrochemical biosensors, focusing particularly on impedimetric biosensors for the direct measurement of analytes.
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A new colorimetric aptasensor for paraquat detection based on the designed aptamer with multiple paraquat binding sites in combination with gold nanoparticles

Anal. Methods, 2024, 16,2340-2348
DOI: 10.1039/D4AY00053F, Paper
Pakawat Kongpreecha, Sineenat Siri
Given paraquat's environmental health risks, there is a need for a fast and simple detection method. This study presents a novel colorimetric aptasensor with a tailored aptamer, boosting sensitivity by targeting multiple paraquat binding sites.
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Online quantification of nicotine in e-cigarette aerosols by vacuum ultraviolet photoionization mass spectrometry

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00279B, Paper
Shaoxin Ye, Zuoying Wen, Kai Xie, Xuejun Gu, Jian Wang, Xiaofeng Tang, Weijun Zhang
A new method for quantifying nicotine in e-cigarette aerosols within a few seconds using a homemade VUV-AMS.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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An immunochromatographic strip sensor for rapid and sensitive detection of candesartan, olmesartan medoxomil, and irbesartan in herbal beverages

Anal. Methods, 2024, 16,2359-2367
DOI: 10.1039/D4AY00151F, Paper
Dingyu Li, Aihong Wu, Liqiang Liu, Hua Kuang, Chuanlai Xu, Xiaoling Wu
Sartans, as a class of antihypertensive drugs, pose a threat to human health when illegally added to herbal beverages.
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A novel electrophoretic assisted hydrophobic microdevice for enhancing blood cell sorting: design and numerical simulation

Anal. Methods, 2024, 16,2368-2377
DOI: 10.1039/D4AY00196F, Paper
Xinkun Chen, Xueye Chen
Microfluidic technology has great advantages in the precise manipulation of micro–nano particles, and the hybrid microfluidic separation technology has attracted much attention due to the advantages of both active and passive separation technology at the same time.
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A highly sensitive and selective fluorescent biosensor for breast cancer derived exosomes using click reaction of azide–CD63 aptamer and alkyne-polymer dots

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00146J, Paper
Dumei Ma, Yiting Luo, Xiaoya Zhang, Zehu Xie, Yinghua Yan, Chuan-Fan Ding
A fluorescence method based on Cu-triggered click reaction of azide modified CD63 aptamer and alkyne capped Pdots was developed for breast cancer derived exosome detection.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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Analysis of brominide disinfection by-products in aquaculture water using ultra-high-performance liquid chromatography–quadrupole–time-of-flight mass spectrometry

Anal. Methods, 2024, Accepted Manuscript
DOI: 10.1039/D4AY00396A, Paper
Weimin Yang, Yi Zhang, Jilong Huang, Xing Yang, Ning Jiang
Background: Halogenic disinfectants have been shown to produce toxic and carcinogenic disinfection by-products (DBPs) during water disinfection. Dibromohydantoin (DBDMH) is a commonly used water disinfectant in aquaculture. Aquaculture water has...
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Detection of Free DNA Based on Metal-Enhanced Fluorescence Triggered by CRISPR-Cas12a and Colorimetric Analysis

Anal. Methods, 2024, Accepted Manuscript
DOI: 10.1039/D4AY00149D, Paper
Ming-Qiu Zheng, Yuyao Li, Liling Zhang, Cheng-Yu Li, Menghan Liu, Hongwu Tang
The CRISPR-Cas system has been found to be extremely sensitive and there is an urgent demand to extend its potential in bioassay. Herein, we developed a novel nanobiosensor to detect...
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A simple and rapid colorimetric detection of Staphylococcus Aureus relied on the distance-dependent optical properties of silver nanoparticles

Anal. Methods, 2024, Accepted Manuscript
DOI: 10.1039/D3AY02189K, Paper
Ngoc Anh Thu Phan, Hoang Men Nguyen, Cam Duyen Thi Vo, Toi Vo Van, Phuoc Long Truong
The quick and accurate diagnosis of pathogens has appeared as a pressing issue in clinical diagnostics, environmental monitoring, and food safety. The current assays are suffering from limited capacities in...
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Paper-based sensors: affordable, versatile, and emerging analyte detection platforms

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D3AY02258G, Critical Review
Open Access
Sumit Malik, Joginder Singh, Kajal Saini, Vivek Chaudhary, Ahmad Umar, Ahmed A. Ibrahim, Sheikh Akbar, Sotirios Baskoutas
The schematic representation of distance based paper sensor to identify lead in food samples.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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Simple fluorescence “turn-off” assay for Congo red using commercial 2-aminophthalic acid

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00506F, Paper
Jiaqi Qian, Jie Li, Yihan Jiang, Chaoyong Liu, Jiayao Zhu, Liyu Gu, Yongming Guo
2-Aminophthalic acid with a high quantum yield of 38.49% was utilized for fluorescence “turn-off” sensing of Congo red with a linear range of 0.05–50 μM and a limit of detection of 1.72 μM.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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A reaction based carbazole–indolium conjugate probe for the selective detection of environmentally toxic ions

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00301B, Paper
Jayasudha Palanisamy, Mansour K. Gatasheh, Ashraf Atef Hatamleh
Carbazole–indolium based colorimetric probe was designed for detecting cyanide ions in various water samples. An outstanding response was shown by paper test strips prepared using the probe for the easy detection of cyanide in real time.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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Electroanalysis overview: additive manufactured biosensors using fused filament fabrication

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00278D, Minireview
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Robert D. Crapnell, Craig E. Banks
Additive manufacturing (3D-printing), in particular fused filament fabrication, presents a paradigm shift in the way electrochemical based biosensing platforms are produced, giving rise to a new generation of personalized and on-demand biosensors.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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Quantifying platinum binding on protein-functionalized magnetic microparticles using single particle-ICP-TOF-MS

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00268G, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Veronica C. Bradley, Benjamin T. Manard, Lyndsey Hendriks, Daniel R. Dunlap, Amber N. Bible, Ada Sedova, Patricia Saint-Vincent, Brian C. Sanders, Hunter B. Andrews
This work describes an analytical procedure, single particle-inductively coupled plasma-time-of-flight-mass spectrometry (SP-ICP-TOF-MS), that was developed to determine the platinum binding efficiency of protein-coated magnetic microparticles.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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Polymeric membrane potentiometric sensors based on template-removal-free imprinted receptors for determination of antibiotics

Anal. Methods, 2024, Accepted Manuscript
DOI: 10.1039/D4AY00263F, Paper
Xinyao Wang, Guohua Cui, Rongning Liang, Wei Qin
Currently, Nernstian-response-based polymeric membrane potentiometric sensors using the molecularly imprinted polymers (MIPs) as the receptors have been successfully developed for determination of organic ionic species. However, the preparation of these...
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Proximity hybridization based “turn-on” DNA tweezer for accurate and enzyme-free small extracellular vesicles analysis

Anal. Methods, 2024, Accepted Manuscript
DOI: 10.1039/D4AY00487F, Paper
Jinlin Wu, Xi Mei, Xiaoqin Zhan, Fang Liu, Dongfang Liu
Small extracellular vesicles (sEVs) are a type of extracellular vesicles that carry many types of molecular information. The identification of sEVs is essential for the non-invasive detection and treatment of...
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Design and fabrication of La-based perovskites incorporated with functionalized carbon nanofibers for the electrochemical detection of roxarsone in water and food samples

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00264D, Paper
Mariya Antony John Felix, Santhiyagu Sahayaraj Rex Shanlee, Shen-Ming Chen, Sundaresan Ruspika, Ramachandran Balaji, Narendhar Chandrasekar, Periyanayagam Arockia Doss
Fabrication of potent electrocatalyst, La-based perovskites coupled with functionalized carbon nanofibers (LMO/f-CNF) for ultrasensitive electrochemical detection of roxarsone in edible and water samples.
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The preparation of a boronate affinity-based controlled oriented imprinting coating on a silica nanoparticle surface for the separation and purification of shikimic acid in herbal medicine

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00219A, Paper
Yumin Yang, Daojin Li, Bingqian Liu
Shikimic acid (SA) is one of the most effective drugs against the A (H1N1) virus and has high medicinal value.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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Α simplified lateral flow immunosensor for the assay of carcinoembryonic antigen in low-resource settings

Anal. Methods, 2024, Accepted Manuscript
DOI: 10.1039/D4AY00381K, Paper
Open Access
Ioanna Tsogka, Electra Mermiga, Varvara Pagkali, Christos Kokkinos, Anastasios Economou
Carcinoembryonic antigen (CEA) is a glycoprotein widely used as a tumor marker. In this work, a colorimetric lateral flow immunosensor is developed for rapid and low-cost quantification of CEA in...
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A chemodosimetric chemosensor for the ratiometric detection of nerve agent-mimic DCP in solution and vapor phases

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00451E, Paper
Shilpita Banerjee, Pintu Ghosh, Anirban Karak, Dipanjan Banik, Ajit Kumar Mahapatra
The probe MNFZ undergoes a hydrolysis reaction in the presence of DCP to exhibit a naked eye color change from blue to cyan. It was successfully applied to sense DCP in the vapor phase.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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Novel advanced materials and magnetic solid phase extraction as approaches in sample preparation to enhance the analysis of ochratoxin A in peanuts

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00246F, Paper
Bingchen Wang, Yifan Wang, Xiuyuan Zhang, Kuo He
In order to improve the detection efficiency of ochratoxin, a superparamagnetic nano-material was synthesized for solid phase extraction of ochratoxin.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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Three-dimensional hotspot structures constructed from nanoporous gold with a V-cavity and gold nanoparticles for surface-enhanced Raman scattering

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00348A, Paper
Yang Xu, Yan Wu, Jianjun Wei, Yuanyu Zhao, Peili Xue
A nanoporous gold V-shaped resonant cavity (NPGVRC) structure constructed with plasmonic resonance coupling effect. The NPGVRC has excellent SERS performance and 3D hotspot properties.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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A highly selective probe engineered to detect polarity and distinguish normal cells and tumor cells in tissue sections

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00438H, Paper
Sai Zhu, Lixuan Dai, Xiaoli Zhong, Weiying Lin
We have designed a polarity fluorescent probe (DCI-Cou-polar) with high selectivity for diagnosing cancer.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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Monolith stationary phases prepared via cyclic anhydride ring-opening polymerization as tunable platforms for chromatographic applications

Anal. Methods, 2024, Accepted Manuscript
DOI: 10.1039/D4AY00251B, Paper
Ahmad Aqel, Ayman Ghafr, A. Yacine Badjah-Hadj-Ahmed, Zeid Abdullah ALOthman
Polymer monolithic stationary phases were prepared based on a cyclic anhydride as a reactive and tunable platform via ring-opening post-polymerization using primary amines; octadecylamine and benzylamine. The characterization techniques indicated...
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A colorimetric tandem combination of CRISPR/Cas12a with dual functional hybridization chain reaction for ultra-sensitive detection of mycobacterium bovis

Anal. Methods, 2024, Accepted Manuscript
DOI: 10.1039/D3AY02200E, Paper
Qiong Liu, Mei Yang, He Zhang, Wenjie Ma, Xin Fu, Huiqing Li, Sainan Gao
Tuberculosis caused by Mycobacterium bovis poses a global infectious threat to humans and animals. Therefore, there is an urgent need to develop a sensitive, precise, and easy-to-readout strategy. Here, a...
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Solutions and Tools for Dealing with Broken Links in Web Pages

A couple of months ago a post by Leo Blanchette got to the front page of Hacker News and there was an interesting discussion on dealing with broken links and external content – the main problem being links that become out of date due to paywalls, altered content, or content getting taken down.

I’ve been running this blog since May 2008. If you’ve run a content-driven site for even a fraction of that, you know that link rot is a problem. In this post I’ll go over some of the suggestions in that thread along with some tools to use to check for broken links.

The post Solutions and Tools for Dealing with Broken Links in Web Pages appeared first on Impressive Webs.



  • HTML5
  • Web Design Articles

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Fading in a Page on Load with CSS & JavaScript

When I visit a page, I get annoyed when I try to interact with elements while the website is still loading. Often stuff is moving around, fonts aren’t quite loaded, and it feels broken.

I know nowadays we’re obsessed in this industry with gaining every millisecond in page performance. But in a couple of projects that I recently overhauled, I added a subtle and clean loading mechanism that I think makes the experience nicer, even if it does ultimately slightly delay the time that the user is able to start interacting with my page.

The post Fading in a Page on Load with CSS & JavaScript appeared first on Impressive Webs.




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Are These the Most Interesting Front-end Developer Tools for 2021?

When I come to the end of any given year, it’s always interesting to look back through the click-through stats for my weekly newsletter Web Tools Weekly to see which tools got the most attention.

This year wasn’t all that different from previous years. I’ve learned that clicks happen for basically one of two reasons:

The post Are These the Most Interesting Front-end Developer Tools for 2021? appeared first on Impressive Webs.



  • Roundups and Resources

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A Review of ipwhois.io for Reliable Geolocation Data

[Sponsored] If you’re building an app that requires delivering a dynamic experience based on the user’s location or other location-related data, a fast and easy-to-use Geolocation API will certainly come in handy. One such option is ipwhois.io. The service, which is free for small non-commercial projects that need fewer than 10,000 requests per month, is easy to integrate with your tech stack.

As usual, it’s always best to look at a few examples so you can see it in action. Their documentation is short and easy to follow, so I’ll demonstrate using the following example request:

The post A Review of ipwhois.io for Reliable Geolocation Data appeared first on Impressive Webs.




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How to Disable JavaScript in Almost Any Browser

In 2022 I think it’s still important as a web developer to test your how your websites look and function when users disable JavaScript in their browser. Developing in this way used to be a cornerstone of Progressive Enhancement and can be handy on both desktop or mobile.

I still find myself wanting disabling JavaScript on pages I visit. Sometimes it’s to test a page I’m working on, but in other instances it’s simply to visit a web page that’s not functioning correctly and I want to see if JavaScript is the culprit.

The post How to Disable JavaScript in Almost Any Browser appeared first on Impressive Webs.




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Filestack: A File Uploader and Powerful APIs to Deliver and Transform App Content

[Sponsored] If you’re building an app that requires a lot of user-generated content and media that needs to be processed, tagged, filtered, or otherwise manipulated in real-time, you definitely want a solution that’s fast and seamless and doesn’t get in the way of your app’s primary functionality. Filestack is a service you’ll want to consider. Here’s what Filestack offers:

The post Filestack: A File Uploader and Powerful APIs to Deliver and Transform App Content appeared first on Impressive Webs.




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Don’t Let ChatGPT Write Your Code

We can all agree it's ridiculous to suggest that we should ignore a modern tool that makes it exponentially easier to finish our work.

But as I've learned in 20+ years of writing code, there's always going to be a drawback to using any tool that "makes life easier". In this case, AI-based tools that use ChatGPT or some other AI-based foundation are similar to the frameworks we've been using for years.

The post Don’t Let ChatGPT Write Your Code appeared first on Impressive Webs.



  • Web Design Articles

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YouTube’s Time-Based UX Problem for Live Sports

I like to play beach volleyball here in the Toronto area. I also watch beach volleyball on YouTube, which includes a lot of live streams from the AVP league in the US. It's a fun sport that I recommend to anyone looking for a new athletic competition to follow.

In most leagues and tournaments, beach volleyball games have a 3-set format, with each set finishing when a team reaches 21 points (or higher if they're not yet ahead by 2). The third set (played if needed) will go up to 15 points (again, win by 2). Some leagues/tournaments will play all three sets up to 15. It depends on the venue, tournament, etc.

The post YouTube’s Time-Based UX Problem for Live Sports appeared first on Impressive Webs.



  • UX
  • Web Design Articles

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Upward bound




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Being Mobile




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More 'dead' mobile services?




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A better Twitter app for Android, at last




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Facebook Home is here. Now what?